Page last updated: 2024-09-05

erlotinib and gsk 1070916

erlotinib has been researched along with gsk 1070916 in 2 studies

Compound Research Comparison

Studies
(erlotinib)
Trials
(erlotinib)
Recent Studies (post-2010)
(erlotinib)
Studies
(gsk 1070916)
Trials
(gsk 1070916)
Recent Studies (post-2010) (gsk 1070916)
221018023019

Protein Interaction Comparison

ProteinTaxonomyerlotinib (IC50)gsk 1070916 (IC50)
Aurora kinase AHomo sapiens (human)1.1795
Cytochrome P450 3A4Homo sapiens (human)0.076
Fibroblast growth factor receptor 1Homo sapiens (human)0.077
Cytochrome P450 2C9 Homo sapiens (human)0.076
Vascular endothelial growth factor receptor 1 Homo sapiens (human)0.042
Vascular endothelial growth factor receptor 3Homo sapiens (human)0.074
Serine/threonine-protein kinase SIK1Homo sapiens (human)0.07
Angiopoietin-1 receptorHomo sapiens (human)0.059
Aurora kinase BHomo sapiens (human)0.0081
Inner centromere proteinHomo sapiens (human)0.0032
Targeting protein for Xklp2Homo sapiens (human)1.1
Aurora kinase CHomo sapiens (human)0.0065

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bantscheff, M; Bergamini, G; Gohlke, B; Gupta, V; Handa, H; Heinzlmeir, S; Helm, D; Klaeger, S; Kuster, B; Médard, G; Perrin, J; Preissner, R; Qiao, H; Savitski, MM1
Aiche, S; Bassermann, F; Becker, W; Canevari, G; Casale, E; Depaolini, SR; Ehrlich, HC; Felder, ER; Feuchtinger, A; Garz, AK; Gohlke, BO; Götze, K; Greif, PA; Hahne, H; Heinzlmeir, S; Helm, D; Huenges, J; Jeremias, I; Kayser, G; Klaeger, S; Koch, H; Koenig, PA; Kramer, K; Kuster, B; Médard, G; Meng, C; Petzoldt, S; Polzer, H; Preissner, R; Qiao, H; Reinecke, M; Reiter, K; Rueckert, L; Ruland, J; Ruprecht, B; Schlegl, J; Schmidt, T; Schneider, S; Schoof, M; Spiekermann, K; Tõnisson, N; Vick, B; Vooder, T; Walch, A; Wilhelm, M; Wu, Z; Zecha, J; Zolg, DP1

Other Studies

2 other study(ies) available for erlotinib and gsk 1070916

ArticleYear
Chemical Proteomics Reveals Ferrochelatase as a Common Off-target of Kinase Inhibitors.
    ACS chemical biology, 2016, 05-20, Volume: 11, Issue:5

    Topics: Benzocycloheptenes; Cell Line, Tumor; Ferrochelatase; Heme; Humans; Imidazoles; Indoles; Molecular Docking Simulation; Protein Binding; Protein Kinase Inhibitors; Proteomics; Pyrazines; Pyridines; Quinolines; Sulfonamides; Vemurafenib

2016
The target landscape of clinical kinase drugs.
    Science (New York, N.Y.), 2017, 12-01, Volume: 358, Issue:6367

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cytokines; Drug Discovery; fms-Like Tyrosine Kinase 3; Humans; Leukemia, Myeloid, Acute; Lung Neoplasms; Mice; Molecular Targeted Therapy; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Proteomics; Xenograft Model Antitumor Assays

2017