Compounds > erlotinib
Page last updated: 2024-09-05

erlotinib and genistein

erlotinib has been researched along with genistein in 7 studies

Compound Research Comparison

Studies
(erlotinib)		Trials
(erlotinib)		Recent Studies (post-2010)
(erlotinib)		Studies
(genistein)		Trials
(genistein)		Recent Studies (post-2010) (genistein)
22101807,4232042,311

Protein Interaction Comparison

ProteinTaxonomyerlotinib (IC50)genistein (IC50)
Chain A, Estrogen receptor 1 (alpha)Homo sapiens (human)0.009
Maltase-glucoamylase, intestinalHomo sapiens (human)2.61
Steroid hormone receptor ERR2Homo sapiens (human)0.395
Tyrosine-protein kinase ABL1Homo sapiens (human)5.5
Epidermal growth factor receptorHomo sapiens (human)1.2
TransthyretinHomo sapiens (human)7.8
Estrogen receptorHomo sapiens (human)1.3477
Steroid hormone receptor ERR1Homo sapiens (human)0.01
Polyunsaturated fatty acid lipoxygenase ALOX15Oryctolagus cuniculus (rabbit)9.033
17-beta-hydroxysteroid dehydrogenase type 1Homo sapiens (human)2.21
Protein kinase C alpha typeHomo sapiens (human)1
cAMP-dependent protein kinase catalytic subunit alphaHomo sapiens (human)1
Amine oxidase [flavin-containing] AHomo sapiens (human)4.184
Thromboxane-A synthase Homo sapiens (human)7.72
Amine oxidase [flavin-containing] BHomo sapiens (human)3.9333
Dipeptidyl peptidase 4Homo sapiens (human)0.48
Proteasome subunit beta type-5Homo sapiens (human)9.26
Sodium-dependent serotonin transporterRattus norvegicus (Norway rat)0.395
Tyrosine-protein kinase CSKHomo sapiens (human)1
Dual specificity mitogen-activated protein kinase kinase 4Homo sapiens (human)0.4
Xanthine dehydrogenase/oxidaseBos taurus (cattle)1.73
Aldehyde oxidaseHomo sapiens (human)0.34
Integrase Human immunodeficiency virus 11.1
Estrogen receptor betaHomo sapiens (human)0.3706
Beta-hydroxyacyl-ACP dehydratase precursor (Fatty acid synthesis protein)Plasmodium falciparum (malaria parasite P. falciparum)7
Solute carrier organic anion transporter family member 1B3Homo sapiens (human)3.8905
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)7.85
Solute carrier organic anion transporter family member 1B1Homo sapiens (human)9.1201

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (28.57)29.6817
2010's3 (42.86)24.3611
2020's2 (28.57)2.80

Authors

AuthorsStudies
Bullock, AN; Fedorov, O; Knapp, S; Marsden, B; Müller, S; Pogacic, V; Rellos, P; Schwaller, J; Sundström, M1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Davis, MI; Khan, J; Li, SQ; Patel, PR; Shen, M; Sun, H; Thomas, CJ1
Cao, Z; Duan, ZA; Han, TJ; Li, YQ; Li, Z; Wang, L; Yang, F; Zhao, WJ1
Bharate, SB; Raghuvanshi, R1
Caballero, E; García-Cárceles, J; Gil, C; Martínez, A1

Reviews

1 review(s) available for erlotinib and genistein

ArticleYear
Kinase Inhibitors as Underexplored Antiviral Agents.
    Journal of medicinal chemistry, 2022, 01-27, Volume: 65, Issue:2

    Topics: Animals; Antiviral Agents; Drug Repositioning; Humans; Protein Kinase Inhibitors; Virus Diseases; Viruses

2022

Other Studies

6 other study(ies) available for erlotinib and genistein

ArticleYear
A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases.
    Proceedings of the National Academy of Sciences of the United States of America, 2007, Dec-18, Volume: 104, Issue:51

    Topics: Amino Acid Sequence; Binding Sites; Clinical Trials as Topic; Drug Evaluation, Preclinical; Enzyme Stability; Humans; Molecular Sequence Data; Phylogeny; Protein Array Analysis; Protein Conformation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases

2007
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Identification of potent Yes1 kinase inhibitors using a library screening approach.
    Bioorganic & medicinal chemistry letters, 2013, Aug-01, Volume: 23, Issue:15

    Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship

2013
Phosphoramidate protides of five flavones and their antiproliferative activity against HepG2 and L-O2 cell lines.
    European journal of medicinal chemistry, 2016, Apr-13, Volume: 112

    Topics: Amides; Antineoplastic Agents; Apoptosis; Cell Cycle Checkpoints; Cell Line; Cell Proliferation; Flavones; Hep G2 Cells; Humans; Liver; Liver Neoplasms; Phosphoric Acids

2016
Recent Developments in the Use of Kinase Inhibitors for Management of Viral Infections.
    Journal of medicinal chemistry, 2022, 01-27, Volume: 65, Issue:2

    Topics: Antiviral Agents; COVID-19; COVID-19 Drug Treatment; Drug Approval; Drug Repositioning; High-Throughput Screening Assays; Humans; Protein Kinase Inhibitors; SARS-CoV-2; United States; United States Food and Drug Administration; Virus Diseases

2022