Page last updated: 2024-09-05

erlotinib and docetaxel

erlotinib has been researched along with docetaxel in 2 studies

Compound Research Comparison

Studies
(erlotinib)
Trials
(erlotinib)
Recent Studies (post-2010)
(erlotinib)
Studies
(docetaxel)
Trials
(docetaxel)
Recent Studies (post-2010) (docetaxel)
2210180101033

Protein Interaction Comparison

ProteinTaxonomyerlotinib (IC50)docetaxel (IC50)
Tubulin beta-4A chainHomo sapiens (human)0.5
Tubulin beta chainHomo sapiens (human)0.5
Cytochrome P450 3A4Homo sapiens (human)2
Tubulin alpha-3C chainHomo sapiens (human)0.5
Substance-K receptorHomo sapiens (human)1.563
Tubulin alpha-1B chainHomo sapiens (human)0.5
Tubulin alpha-4A chainHomo sapiens (human)0.5
Tubulin beta-4B chainHomo sapiens (human)0.5
Growth hormone-releasing hormone receptorHomo sapiens (human)0.0001
Tubulin beta-3 chainHomo sapiens (human)0.5
Tubulin beta-2A chainHomo sapiens (human)0.5
Tubulin beta-8 chainHomo sapiens (human)0.5
Tubulin alpha-3E chainHomo sapiens (human)0.5
Tubulin alpha-1A chainHomo sapiens (human)0.5
Tubulin alpha-1C chainHomo sapiens (human)0.5
Tubulin beta-6 chainHomo sapiens (human)0.5
Tubulin beta-2B chainHomo sapiens (human)0.5
Tubulin beta-1 chainHomo sapiens (human)0.5

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Benfenati, E; Raska, I; Toropov, AA; Toropova, AP1
Bailey-Downs, LC; Bastian, A; Disch, BC; Dybdal-Hargreaves, NF; Gangjee, A; Hamel, E; Ihnat, M; Mooberry, SL; Raghavan, S; Rohena, CC; Thorpe, JE; Zhang, X1

Other Studies

2 other study(ies) available for erlotinib and docetaxel

ArticleYear
QSPR modeling of octanol/water partition coefficient of antineoplastic agents by balance of correlations.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:4

    Topics: Antineoplastic Agents; Models, Chemical; Octanols; Quantitative Structure-Activity Relationship; Water

2010
The design and discovery of water soluble 4-substituted-2,6-dimethylfuro[2,3-d]pyrimidines as multitargeted receptor tyrosine kinase inhibitors and microtubule targeting antitumor agents.
    Bioorganic & medicinal chemistry, 2014, Jul-15, Volume: 22, Issue:14

    Topics: Aniline Compounds; Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Discovery; Drug Screening Assays, Antitumor; Female; HeLa Cells; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Microtubules; Neoplasms, Experimental; Protein Kinase Inhibitors; Pyrimidines; Receptor Protein-Tyrosine Kinases; Solubility; Structure-Activity Relationship; Water

2014