Page last updated: 2024-09-05

erlotinib and colchicine

erlotinib has been researched along with colchicine in 7 studies

Compound Research Comparison

Studies
(erlotinib)
Trials
(erlotinib)
Recent Studies (post-2010)
(erlotinib)
Studies
(colchicine)
Trials
(colchicine)
Recent Studies (post-2010) (colchicine)
221018015,4724042,974

Protein Interaction Comparison

ProteinTaxonomyerlotinib (IC50)colchicine (IC50)
Tubulin alpha-1A chainSus scrofa (pig)3.7639
Tubulin beta chainSus scrofa (pig)3.8663
Tubulin beta-4A chainHomo sapiens (human)2.4334
Tubulin beta chainHomo sapiens (human)2.7244
Tubulin alpha-3C chainHomo sapiens (human)2.4334
Serine/threonine-protein kinase pim-1Homo sapiens (human)4.3
Tubulin alpha-1B chainHomo sapiens (human)2.4334
Tubulin alpha-4A chainHomo sapiens (human)2.4334
Tubulin beta-4B chainHomo sapiens (human)2.4334
Vesicular acetylcholine transporterTetronarce californica (Pacific electric ray)2.62
Tubulin beta-3 chainHomo sapiens (human)2.4334
Tubulin beta-2A chainHomo sapiens (human)2.4334
Tubulin beta-8 chainHomo sapiens (human)2.4334
Tubulin beta-2B chainBos taurus (cattle)2.8255
Tubulin alpha-3E chainHomo sapiens (human)2.4334
Tubulin alpha-1A chainHomo sapiens (human)2.4334
Similar to alpha-tubulin isoform 1 Bos taurus (cattle)3.0611
Similar to alpha-tubulin isoform 1 Bos taurus (cattle)3.1553
Tubulin alpha-1C chainHomo sapiens (human)2.4334
Tubulin beta-6 chainHomo sapiens (human)2.4334
Tubulin beta-2B chainHomo sapiens (human)2.4334
Tubulin beta-1 chainHomo sapiens (human)2.4334

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (14.29)29.6817
2010's3 (42.86)24.3611
2020's3 (42.86)2.80

Authors

AuthorsStudies
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
El-Ashmawy, MB; El-Gohary, NS; Shehata, IA; Warda, ET1
Abuo-Rahma, GEA; Badr, M; Bass, AKA; El-Zoghbi, MS; Mohamed, MFA; Nageeb, EM1
Arya, GC; Jaitak, V; Kaur, K1

Reviews

3 review(s) available for erlotinib and colchicine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Comprehensive review for anticancer hybridized multitargeting HDAC inhibitors.
    European journal of medicinal chemistry, 2021, Jan-01, Volume: 209

    Topics: Androgen Antagonists; Animals; Antineoplastic Agents; Benzimidazoles; Cyclic Nucleotide Phosphodiesterases, Type 5; Daunorubicin; Doxorubicin; fms-Like Tyrosine Kinase 3; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Molecular Targeted Therapy; Morpholines; Nicotinamide Phosphoribosyltransferase; Nitric Oxide; Pyrimidines; Quinazolines; Structure-Activity Relationship; Transcription Factors

2021
Isoxazole derivatives as anticancer agent: A review on synthetic strategies, mechanism of action and SAR studies.
    European journal of medicinal chemistry, 2021, Oct-05, Volume: 221

    Topics: Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Proliferation; Drug Screening Assays, Antitumor; Female; Humans; Isoxazoles

2021

Other Studies

4 other study(ies) available for erlotinib and colchicine

ArticleYear
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
New series of isoxazole derivatives targeting EGFR-TK: Synthesis, molecular modeling and antitumor evaluation.
    Bioorganic & medicinal chemistry, 2020, 11-01, Volume: 28, Issue:21

    Topics: Apoptosis; Binding Sites; Caspase 3; Cell Line, Tumor; Cell Survival; DNA Topoisomerases, Type II; Drug Design; Drug Screening Assays, Antitumor; ErbB Receptors; G2 Phase Cell Cycle Checkpoints; Humans; Isoxazoles; Molecular Docking Simulation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-bcl-2; Structure-Activity Relationship; Up-Regulation; Vascular Endothelial Growth Factor Receptor-2

2020