Page last updated: 2024-09-05

erlotinib and cb676475

erlotinib has been researched along with cb676475 in 3 studies

Compound Research Comparison

Studies
(erlotinib)
Trials
(erlotinib)
Recent Studies (post-2010)
(erlotinib)
Studies
(cb676475)
Trials
(cb676475)
Recent Studies (post-2010) (cb676475)
22101801706

Protein Interaction Comparison

ProteinTaxonomyerlotinib (IC50)cb676475 (IC50)
Fibroblast growth factor receptor 1Homo sapiens (human)4.025
Vascular endothelial growth factor receptor 1 Homo sapiens (human)2.35
Ephrin type-B receptor 2Homo sapiens (human)8.5
Vascular endothelial growth factor receptor 3Homo sapiens (human)1
Vascular endothelial growth factor receptor 2Homo sapiens (human)1.95

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gangjee, A; Ihnat, MA; Kurup, S; Shenoy, SS; Thorpe, JE1
Disch, B; Gangjee, A; Ihnat, MA; Kurup, S; Thorpe, JE1
Bailey-Downs, LC; Gangjee, A; Ihnat, MA; Namjoshi, OA; Thorpe, JE; Yu, J1

Other Studies

3 other study(ies) available for erlotinib and cb676475

ArticleYear
Synthesis and biological activity of N(4)-phenylsubstituted-6-(2,4-dichloro phenylmethyl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamines as vascular endothelial growth factor receptor-2 inhibitors and antiangiogenic and antitumor agents.
    Bioorganic & medicinal chemistry, 2010, May-15, Volume: 18, Issue:10

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Cell Line, Tumor; Diamines; Indoles; Male; Melanoma; Mice; Mice, Nude; Molecular Structure; Phosphorylation; Pyrimidines; Pyrimidinones; Pyrroles; Structure-Activity Relationship; Vascular Endothelial Growth Factor Receptor-2

2010
N⁴-Aryl-6-substitutedphenylmethyl-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamines as receptor tyrosine kinase inhibitors.
    Bioorganic & medicinal chemistry, 2012, Jan-15, Volume: 20, Issue:2

    Topics: Antineoplastic Agents; Cell Line, Tumor; Diamines; Enzyme Activation; ErbB Receptors; Humans; Protein Kinase Inhibitors; Pyrimidines; Vascular Endothelial Growth Factor Receptor-1; Vascular Endothelial Growth Factor Receptor-2

2012
N2-Trimethylacetyl substituted and unsubstituted-N4-phenylsubstituted-6-(2-pyridin-2-ylethyl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamines: design, cellular receptor tyrosine kinase inhibitory activities and in vivo evaluation as antiangiogenic, antimetastati
    Bioorganic & medicinal chemistry, 2013, Mar-01, Volume: 21, Issue:5

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Disease Models, Animal; Drug Design; Humans; Melanoma, Experimental; Mice; Mice, Nude; Microwaves; Protein Kinase Inhibitors; Pyrimidines; Pyrroles; Receptor Protein-Tyrosine Kinases; Structure-Activity Relationship

2013