ergoline has been researched along with propadiene* in 1 studies
1 other study(ies) available for ergoline and propadiene
Article | Year |
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Total synthesis of (+/-)-lysergic acid, lysergol, and isolysergol by palladium-catalyzed domino cyclization of amino allenes bearing a bromoindolyl group.
Ergot alkaloids and their synthetic analogs have been reported to exhibit broad biological activity. We investigated direct construction of the C/D ring system of ergot alkaloids based on palladium-catalyzed domino cyclization of amino allenes. With this biscyclization as the key step, total synthesis of (+/-)-lysergic acid, (+/-)-lysergol, and (+/-)-isolysergol was achieved. Topics: Alkadienes; Bromine; Catalysis; Cyclization; Ergolines; Indoles; Lysergic Acid; Palladium; Stereoisomerism | 2008 |