Page last updated: 2024-08-24

erdosteine and thiophenes

erdosteine has been researched along with thiophenes in 150 studies

Research

Studies (150)

Timeframe	Studies, this research(%)	All Research%
pre-1990	6 (4.00)	18.7374
1990's	13 (8.67)	18.2507
2000's	64 (42.67)	29.6817
2010's	55 (36.67)	24.3611
2020's	12 (8.00)	2.80

Authors

Authors	Studies
Ciaccia, A; Fregnan, B; Papi, A; Tschirky, B	1
Casalini, A; D'Ippolito, R; Del Donno, M; Fregnan, GB; Olivieri, D	1
Amato, A; Civello, IM; De Giovanni, L; Fregnan, GB; Murari, G; Rabitti, C; Sovera, A	1
Casadei, MC; Fregnan, GB; Guerzoni, P; Marchioni, CF; Moretti, M; Muratori, M; Scuri, R	1
Biagi, GL; Fregnan, GB; Gazzani, G; Vandoni, G	1
Fregnan, GB; Vagliasindi, M	1
Fregnan, GB; Gazzani, G; Vandoni, G	1
Fregnan, GB; Gazzani, G; Mazzone, A; Ricevuti, G; Uccelli, E	1
Giannetti, P; Paesano, A; Scuri, R	1
Bradamante, S; Gobetti, M; Pedrazzoli, A	1
Bradamante, S; Fregnan, GB; Inglesi, M; Nicola, M; Pagani, G	1
Hanard, T; Mancini, C; Marchioni, CF; Noseda, G; Polu, JM; Taytard, A	1
Dechant, KL; Noble, S	1
Kobayashi, S; Muramatsu, N; Toyo'oka, T; Yamaguchi, K	1
Hosoe, H; Kaise, T; Ohmori, K	2
Braga, PC; Dal Sasso, M; Gianelle, V; Sala, MT	1
Akuta, K; Hosoe, H; Kaise, T; Manabe, H; Miyake, K; Ohmori, K	1
Hosoe, H; Isohama, Y; Kai, H; Kaise, T; Miyata, T; Ohmori, K; Takahama, K	1
Aubier, M; Berdah, L	1
Fazzio, S; Lizzio, A; Mancini, C; Negri, P; Termini, C; Titti, G	1
Mancini, C; Mitrea, M; Savu, S; Silvestro, L	1
Braga, PC; Dal Sasso, M; Zuccotti, T	1
Hayashi, K; Hosoe, H; Kaise, T; Ohmori, K	1
Bovio, C; Braga, PC; Culici, M; Dal, SM	1
Bovio, C; Braga, PC; Culici, M; Dal Sasso, M; Fonti, E	1
Akyol, O; Iraz, M; Kotuk, M; Odaci, E; Ozyurt, H; Sogut, S; Yildirim, Z	1
Erdoğan, H; Fadillioğlu, E	1
Han, ES; Jang, YY; Lee, CS; Shin, YK; Song, JH	1
Erdogan, H; Fadillioglu, E; Irmak, MK; Sogut, S; Ucar, M; Yagmurca, M	1
Erdogan, H; Fadillioglu, E; Sogut, S; Yilmaz, HR	1
Chang, KY; Han, SB; Kim, H; Lee, HJ; Lee, KR	1
Bianchi, T; Braga, PC; Culici, M; Dal Sasso, M; Fonti, E	1
Akyol, O; Armutcu, F; Iraz, M; Kaplan, S; Kart, L; Ozen, S; Ozyurt, H; Sogut, S; Temel, I; Yildirim, Z	1
Akyol, O; Gergerlioglu, S; Iraz, M; Ozyurt, H; Sogut, S; Yildirim, Z; Yilmaz, HR	1
Akyol, O; Ege, E; Gurel, A; Ilhan, A; Ozen, S	1
Akyol, O; Armutcu, F; Aydogdu, I; Gurel, A; Iraz, M; Kotuk, M; Ozen, S; Turkoz, Y; Yildirim, Z	1
Bottrighi, P; Da Porto, R; Dallari, R; De Gugliemo, M; Dolcetti, A; Garuti, G; Grandi, P; Guffanti, E; Moretti, M; Potena, A; Roversi, P	1
Akyol, O; Egri, M; Gulec, M; Iraz, M; Kalcioglu, MT; Karatas, E; Kizilay, A; Ozturan, O	1
Bianchi, T; Braga, PC; Culici, M; Dal Sasso, M; Fonti, E; Guffanti, EE	1
Basyigit, I; Bulut, O; Cekmen, M; Duman, C; Yildiz, F	1
Aladag, MA; Armutcu, F; Boluk, A; Gurel, A; Ilhan, A; Kocer, A	1
Armutcu, F; Iraz, M; Kotuk, M; Kuku, I; Ozen, S; Ulu, R; Yildirim, Z	1
Fadillioglu, E; Idiz, N; Ilhan, A; Iraz, M; Sahin, S; Terzi, A	1
Arslan, MK; Candir, O; Ciris, M; Oktem, F; Ozguner, F; Uz, E; Yilmaz, HR	1
Cicek, E; Delibas, N; Gokalp, O; Ozcelik, N; Ozer, MK; Sutcu, R; Uz, E; Yilmaz, HR	1
Akcan, R; Ciralik, H; Duru, M; Koc, A; Sogut, S	1
Akaydin, Y; Duru, M; Gergerlioglu, HS; Koc, A; Narci, A; Sogut, S	1
Başyiğit, I; Boyaci, H; Dillioğlugil, MO; Erçin, C; Maral, H; Pala, A; Tugay, M; Turan, G; Yildiz, F	1
Demiralay, R; Erdem, H; Gürsan, N	3
Erdogan, H; Fadillioglu, E; Irmak, MK; Uçar, M; Yagmurca, M	1
Akcay, A; Bayrak, R; Isik, B; Sogut, S	1
Arbak, P; Balbay, O; Comunoğlu, NU; Erbaş, M; Güler, S; Nihat Annakkaya, A; Silan, C; Uzun, O; Yavuz, O	1
Arslan, C; Cam, H; Olgar, S; Sahin, M; Tunc, SE; Uz, E; Yilmaz, HR	1
Braga, PC; Culici, M; Dal Sasso, M; Lo Verso, R; Marabini, L; Verducci, P	1
Alkan, A; Alsancak, G; Cerçi, C; Ergin, C; Eroğlu, E; Eroğlu, F	1
Ercan, F; Gedik, N; Sehirli, AO; Sener, G; Toklu, HZ; Yuksel, M	1
Assereto, R; Balli, F; Bergamini, B; Calistru, P; Ciofu, EP; Domenici, R; Doros, G; Dragomir, D; Gherghina, I; Iordachescu, F; Murgoci, G; Orasanu, D; Plesca, D; Vaccaro, A	1
Marchioni, CF; Moretti, M	1
Bas, O; Karaman, O; Mollaoglu, H; Nacar, A; Sahin, O; Songur, A; Yagmurca, M	1
Aksoy, H; Aral, C; Cetinel, S; Gedik, N; Sehirli, O; Sener, G; Yeğen, BC; Yüksel, M	1
Ağaçkiran, Y; Altuntaş, I; Delibaş, N; Kilbaş, A; Sirmali, M; Sirmali, R; Uz, E; Yilmaz, HR	1
Akcay, A; Bayrak, R; Karanfil, A; Kaya, A; Ozkara, A; Sahin, S; Selcoki, Y; Uz, B; Uz, E	1
Altuntaş, I; Delibaş, N; Kilbaş, A; Naziroğlu, M; Sirmali, M; Sirmali, R; Uz, E; Vural, H; Yilmaz, HR	1
Dal Negro, RW; Micheletto, C; Tognella, S; Visconti, M	2
Cabuk, M; Demircan, N; Gurel, A; Sen, F	1
Bertini, M; Clini, EM; Coletti, O; Costi, S; Crisafulli, E; Fabbri, LM; Lorenzi, C; Lucic, S; Zanasi, E	1
Dal Negro, RW	1
Duru, M; Helvaci, R; Kaya, H; Koc, A; Kozlu, T; Kuvandik, G; Nacar, A; Sogüt, S; Yonden, Z	1
Cobanoğlu, B; Deveci, F; Erden, ES; Ilhan, N; Kirkil, G; Muz, MH; Turgut, T	1
Akyol, O; Bilgic, S; Cigli, A; Ilhan, A; Iraz, M; Ozerol, E	1
Ciçek, E; Gökalp, O; Ozçelik, N; Ozer, MK; Uz, E; Yilmaz, HR	1
Güven, A; Korkmaz, A; Kul, M; Ongürü, O; Oter, S; Sarici, U; Topal, T; Tunc, T	1
Bertacco, S; Dal Negro, R; Micheletto, C; Tognella, S; Trevisan, F; Visconti, M	1
Ağackiran, Y; Naziroğlu, M; Ozden, A; Sirmali, R; Uz, E; Vural, H; Yesildağ, A; Yesildağ, M; Yilmaz, HR; Yilmaz, N	1
Moretti, M	1
Dogan, M; Donmez, S; Gokalp, O; Gumral, N; Karahan, N; Kocak, A; Koyu, A; Oktem, F; Yilmaz, N	1
Atabek, C; Caliskan, B; Ersoz, N; Guven, A; Kesik, V; Oter, S; Oztas, E; Tunc, T; Uysal, B	1
Karapolat, S	1
Avunduk, MC; Barişkaner, H; Byükbaş, S; Ertemli, E; Gokçe, G; Kocabas, V; Kulaksizoglu, H; Pişkin, MM; Yurdakul, T	1
Cazzola, M; Floriani, I; Page, CP	1
Kim, HS; Kim, MC; Lee, JY; Park, CS	1
Aydin, S; Guler, N; Kilic, A; Kilic, G; Oguz, F; Sidal, M; Tamay, Z; Toprak, S; Unuvar, E; Yildiz, I	1
Braga, PC; Culici, M; Dal Sasso, M; Falchi, M; Spallino, A	1
Abut, E; Bölükbaş, C; Bölükbaş, FF; Dalay, AR; Güveli, H; Kurdaş, OO; Yaşar, B	1
Aydin, M; Davarci, M; Gökçe, A; Koç, A; Meydan, S; Oktar, S; Oztürk, OH	1
Bayrak, R; Delibasi, T; Ekiz, F; Erarslan, E; Koca, C; Turkcu, UO; Uz, B	1
Erbaş, M; Erkan, ME; Gezer, S; Güneş, H; Kandiş, H; Kara, IH; Yildirim, HA; Yildirim, U	1
Arica, S; Arica, V; Basarslan, F; Erden, ES; Kaya, H; Oktar, S; Ozturk, OH; Tutanc, M	1
Dhoka, MV; Gandhi, SV; Gawande, VT; Joshi, PP; Patil, NG	1
Dumlu, T; Gezer, S; Iskender, A; Kandis, H; Karapolat, B; Karapolat, S; Ozaydin, I; Saritas, A; Yasar, M; Yildirim, U	1
Akpınar, D; Aslan, M; Derin, N; Ozcan, F; Yargıçoğlu, P	1
Albayrak, A; Aydın Erden, I; Bilgiç, I; Erden, G; Yesilyurt, A	1
Arica, V; Basarslan, F; Nacar, A; Nacar, E; Tutanc, M; Tutanc, OD; Yılmaz, N; Zararsiz, I	1
El Fata, F; Saliba, I	1
Arica, V; Aydin, M; Basarslan, F; Erden, ES; Motor, S; Ozturk, OH; Tutanc, M; Zararsiz, I	1
Daniel, SJ; Dupuis, I; Waissbluth, S	1
Braga, PC; Calò, R; Marabini, L	1
Kang, HR; Kang, MG; Shim, EJ; Sohn, SW; Song, WJ	1
Baltaci, D; Colakoglu, S; Kandis, H; Kara, IH; Karakus, A; Kaya, H; Memisogullari, R; Saritas, A; Yildirim, U	1
Bakar, C; Balbay, O; Gulec Balbay, E; Guven, A; Ickin, M; Uzun, O	1
Ma, L; Wang, WN; Yao, TW; Zhang, LD	1
Chen, XY; Jin, J; Ma, ZY; Zhang, YF; Zhong, DF	1
Hoza, J; Kellnerova, R; Salzman, R; Schalek, P; Starek, I	1
Crockett, A; Crossingham, I; Hart, A; Milan, SJ; Sugumar, K; Wilkinson, M	1
Arli, C; Cevik, C; Dokuyucu, R; Ozgur, T; Ozler, GS; Sefil, F; Yonden, Z	1
Carlson, JM; Deng, W; deSouza, MS; Dommaraju, K; Edlefsen, PT; Geraghty, DE; Kaewkungwal, J; Kijak, G; Kim, JH; Larsen, BB; Maust, BS; Michael, NL; Mullins, JI; Nitayaphan, S; O'Connell, RJ; Pitisuttihum, P; Ratto-Kim, S; Rerks-Ngarm, S; Robb, ML; Rolland, M; Sanders-Buell, E; Tovanabutra, S	1
Dokuyucu, R; Duru, M; Gokce, H; Karateke, A; Karateke, F; Kurt, RK; Ozcan, O; Ozturk, S; Tas, ZA	1
Elkady, AA; Ibrahim, IM	1
Armağan, A; Dönmezs, S; Kirbas, A; Öktem, F; Silay, MS; Sirmali, M; Sirmali, R; Uz, E; Yilmaz, HR	1
Alacam, H; Duran, L; Gunaydin, M; Guzel, A; Kayhan, S; Murat, N; Selcuk, MY; Torun, AC; Tutuncu, S; Yilmaz, MZ	1
Dal Negro, RW; Turco, P; Visconti, M	1
Choe, SK; Hong, GY; Kim, SJ; Lee, JN; Lim, DJ; Lim, H; Moon, SK; Park, C; Park, R	1
Fagnani, S; Moretti, M	1
Akküçük, S; Karaboğa, I; Motor, S; Nacar, A; Nacar, E; Okuyan, HM; Ozkan, OV; Sefil, NK	1
Cho, YJ; Lee, CT; Lee, JH; Lee, SM; Park, JS; Park, MY; Yoo, CG	1
Dal Negro, RW; Visconti, M	1
Akinpelu, OV; Daniel, SJ; Garnier, D; Salehi, P; Waissbluth, S	1
Akoglu, G; Yavuz, SO	1
Erdem, A; Fadillioglu, E; Gedikli, E; Karaismailoglu, S; Muftuoglu, S; Tuncer, M; Yersal, N	1
Fraňová, S; Jošková, M; Kazimierová, I; Pappová, L; Šutovská, M	1
Calzetta, L; Cazzola, M; Hanania, NA; Matera, MG; Rogliani, P	1
Calverley, PMA; Cicero, AF; Dal Negro, RW; Fontana, G; Iversen, M; Page, C; Pozzi, E; Wedzicha, JA	1
Gurleyik, E; Karapolat, B; Karapolat, S; Yasar, M	1
Adiyaman, Z; Barlas, AM; Cavusoglu, T; Celepli, P; Erel, S; Hucumenoglu, S; Kismet, K; Kuru, S; Pekcici, R; Senes, M	1
Calzetta, L; Cazzola, M; Matera, MG; Page, C; Rogliani, P	3
Çomu, FM; Demirtaş, H; Erer, D; Kılıç, Y; Küçük, A; Mardin, B; Oktar, GL; Özer, A	1
Agturk, G; Dogan, H; Dokuyucu, R; Karateke, A; Ozgur, T; Tas, ZA; Tumer, C; Tutuk, O	1
Cella, SG; Dal Negro, R; Pozzi, E	1
Fraňová, S; Jošková, M; Kazimierová, I; Molitorisová, M; Pappová, L; Šutovská, M	1
Calzetta, L; Cazzola, M; Matera, MG; Page, C; Puxeddu, E; Rogliani, P	1
Dobrakowski, M; Kasperczyk, A; Kasperczyk, S; Machoń-Grecka, A; Maciejczyk, M; Nowak, P; Pryzwan, T; Szczęsny, P	1
Calverley, PM; Cazzola, M; Cicero, AF; Dal Negro, RW; Fontana, G; Page, C; Pozzi, E; Wedzicha, JA	1
Chu, X; Huang, X; Ma, X; Ni, B; Tan, G; Xi, Y; You, H; Zhang, R	1
Elwy, HM; Mahrouse, MA; Salem, EM	1
Arya, DS; Bhatia, J; Malik, S; Mutneja, E; Ray, R; Sahu, AK; Verma, VK	1
Adir, Y; Avdeev, S; Calverley, PMA; Cordeiro, CR; Jesenak, M; Koblížek, V; Papi, A; Petkova, D; Rogliani, P; Tarraf, H; Tzanakis, N; Ulmeanu, R; Uzaslan, E	1
Cheng, Q; Liu, H; Pei, K; Wang, J; Xiong, X; Zhong, Z; Zhou, Z	1
Atik, H; Atik, O; Avci, G; Birdane, FM; Birdane, YO; Turkmen, R	1
Cao, L; Cui, G; Gao, H; Han, S; Jiang, X; Li, P; Li, S; Ma, Z; Ning, X; Ping, F; Zhang, F	1
Dugnani, S; Lucini, V; Pani, A; Scaglione, F	1
Bayram, R; Kaya, E; Yaykasli, KO; Yilmaz, I	1
Chang, AB; Chatfield, MD; Cook, AL; D'Antoine, H; Duncan, EL; Fletcher, S; Grimwood, K; Kruljac, C; Leo, PJ; Marchant, JM; McCallum, GB; McElrea, MS; McInerney-Leo, AM; McPhail, SM; Morgan, LC; Morris, PS; O'Farrell, H; Robinson, PJ; Schultz, A; Smith-Vaughan, HC; Stroil-Salama, E; Versteegh, L; Wurzel, D; Yerkovich, ST; Zhao, Y	1

Reviews

11 review(s) available for erdosteine and thiophenes

Article	Year
Erdosteine. Drugs, 1996, Volume: 52, Issue:6 Topics: Animals; Bronchitis; Chronic Disease; Clinical Trials as Topic; Expectorants; Humans; Thioglycolates; Thiophenes	1996
An overview of erdosteine antioxidant activity in experimental research. Pharmacological research, 2007, Volume: 55, Issue:4 Topics: Animals; Antioxidants; Disease Models, Animal; Humans; Lipid Peroxidation; Lung Diseases; Oxidative Stress; Reactive Oxygen Species; Respiratory System Agents; Thioglycolates; Thiophenes	2007
Erdosteine: antitussive and anti-inflammatory effects. Lung, 2008, Volume: 186 Suppl 1 Topics: Animals; Cough; Expectorants; Humans; Oxidative Stress; Respiratory Tract Infections; Thioglycolates; Thiophenes; Treatment Outcome	2008
Erdosteine: its relevance in COPD treatment. Expert opinion on drug metabolism & toxicology, 2009, Volume: 5, Issue:3 Topics: Animals; Antioxidants; Bronchitis; Clinical Trials as Topic; Expectorants; Humans; Pulmonary Disease, Chronic Obstructive; Quality of Life; Severity of Illness Index; Thioglycolates; Thiophenes	2009
The therapeutic efficacy of erdosteine in the treatment of chronic obstructive bronchitis: a meta-analysis of individual patient data. Pulmonary pharmacology & therapeutics, 2010, Volume: 23, Issue:2 Topics: Adult; Aged; Bronchitis, Chronic; Cough; Expectorants; Female; Humans; Male; Middle Aged; Pulmonary Disease, Chronic Obstructive; Randomized Controlled Trials as Topic; Sputum; Thioglycolates; Thiophenes; Viscosity	2010
Mucolytics for bronchiectasis. The Cochrane database of systematic reviews, 2014, May-02, Issue:5 Topics: Anti-Bacterial Agents; Bromhexine; Bronchiectasis; Deoxyribonucleases; Drug Therapy, Combination; Expectorants; Humans; Randomized Controlled Trials as Topic; Recombinant Proteins; Thioglycolates; Thiophenes	2014
Impact of Mucolytic Agents on COPD Exacerbations: A Pair-wise and Network Meta-analysis. COPD, 2017, Volume: 14, Issue:5 Topics: Acetylcysteine; Ambroxol; Carbocysteine; Disease Progression; Expectorants; Humans; Network Meta-Analysis; Pulmonary Disease, Chronic Obstructive; Randomized Controlled Trials as Topic; Thioglycolates; Thiophenes	2017
Impact of erdosteine on chronic bronchitis and COPD: A meta-analysis. Pulmonary pharmacology & therapeutics, 2018, Volume: 48 Topics: Bronchitis, Chronic; Expectorants; Hospitalization; Humans; Pulmonary Disease, Chronic Obstructive; Randomized Controlled Trials as Topic; Thioglycolates; Thiophenes; Treatment Outcome	2018
Erdosteine: Drug exhibiting polypharmacy for the treatment of respiratory diseases. Pulmonary pharmacology & therapeutics, 2018, Volume: 53 Topics: Anti-Bacterial Agents; Drug Therapy, Combination; Expectorants; Humans; Mucociliary Clearance; Mucus; Polypharmacy; Respiratory Tract Diseases; Thioglycolates; Thiophenes	2018
Efficacy and safety profile of mucolytic/antioxidant agents in chronic obstructive pulmonary disease: a comparative analysis across erdosteine, carbocysteine, and N-acetylcysteine. Respiratory research, 2019, May-27, Volume: 20, Issue:1 Topics: Acetylcysteine; Antioxidants; Carbocysteine; Expectorants; Humans; Pulmonary Disease, Chronic Obstructive; Randomized Controlled Trials as Topic; Thioglycolates; Thiophenes; Treatment Outcome	2019
Multifaceted Beneficial Effects of Erdosteine: More than a Mucolytic Agent. Drugs, 2020, Volume: 80, Issue:17 Topics: Administration, Inhalation; Adrenal Cortex Hormones; Antioxidants; Drug Therapy, Combination; Expectorants; Humans; Lung; Oxidative Stress; Practice Guidelines as Topic; Pulmonary Disease, Chronic Obstructive; Symptom Flare Up; Thioglycolates; Thiophenes; Treatment Outcome	2020

Trials

27 trial(s) available for erdosteine and thiophenes

Article	Year
Protection of erdosteine on smoke-induced peripheral neutrophil dysfunction both in healthy and in bronchitic smokers. Fundamental & clinical pharmacology, 1992, Volume: 6, Issue:8-9 Topics: Adult; Aged; Bronchitis; Chemotaxis, Leukocyte; Female; Free Radical Scavengers; Humans; Male; Middle Aged; Neutrophils; Smoking; Thioglycolates; Thiophenes	1992
Activity of erdosteine on mucociliary transport in patients affected by chronic bronchitis. Respiration; international review of thoracic diseases, 1991, Volume: 58, Issue:2 Topics: Aged; Bronchitis; Bronchoscopy; Chronic Disease; Double-Blind Method; Expectorants; Female; Fenoterol; Humans; Male; Middle Aged; Mucociliary Clearance; Mucus; Placebos; Smoking; Thioglycolates; Thiophenes	1991
Lack of gastric adverse effects of erdosteine in rats and men. International journal of clinical pharmacology, therapy, and toxicology, 1991, Volume: 29, Issue:7 Topics: Administration, Oral; Aged; Animals; Carbocysteine; Female; Gastric Mucosa; Homocysteine; Humans; Male; Middle Aged; Peptic Ulcer; Rats; Rats, Inbred Strains; Thioglycolates; Thiophenes; Tiopronin	1991
Effects of erdosteine on sputum biochemical and rheologic properties: pharmacokinetics in chronic obstructive lung disease. Lung, 1990, Volume: 168, Issue:5 Topics: Bronchitis; Chronic Disease; Double-Blind Method; Expectorants; Humans; Male; Rheology; Sputum; Theophylline; Thioglycolates; Thiophenes	1990
Erdosteine protection against cigarette smoking-induced functional antiprotease deficiency in human bronchiolo-alveolar structures. International journal of clinical pharmacology, therapy, and toxicology, 1989, Volume: 27, Issue:5 Topics: Adult; alpha 1-Antitrypsin; alpha 1-Antitrypsin Deficiency; Bronchi; Bronchoalveolar Lavage Fluid; Double-Blind Method; Female; Humans; Male; Middle Aged; Pulmonary Alveoli; Smoking; Thioglycolates; Thiophenes	1989
Influence of erdosteine, a mucolytic agent, on amoxycillin penetration into sputum in patients with an infective exacerbation of chronic bronchitis. Thorax, 1988, Volume: 43, Issue:8 Topics: Aged; Amoxicillin; Bacterial Infections; Bronchitis; Chronic Disease; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Expectorants; Female; Humans; Male; Middle Aged; Sputum; Thioglycolates; Thiophenes	1988
Evaluation of efficacy and safety of erdosteine in patients affected by chronic bronchitis during an infective exacerbation phase and receiving amoxycillin as basic treatment (ECOBES, European Chronic Obstructive Bronchitis Erdosteine Study). International journal of clinical pharmacology and therapeutics, 1995, Volume: 33, Issue:11 Topics: Aged; Amoxicillin; Bronchitis; Chronic Disease; Double-Blind Method; Expectorants; Female; Humans; Male; Middle Aged; Penicillins; Prospective Studies; Thioglycolates; Thiophenes	1995
[Multicenter, controlled, double-blind study of the efficacy and tolerance of Vectrine (erdostein) versus placebo in the treatment of stabilized chronic bronchitis with hypersecretion]. Revue des maladies respiratoires, 1999, Volume: 16, Issue:4 Topics: Administration, Oral; Adult; Aged; Bronchitis; Chronic Disease; Double-Blind Method; Dyspnea; Expectorants; Female; Humans; Male; Middle Aged; Severity of Illness Index; Thioglycolates; Thiophenes; Treatment Outcome	1999
A controlled multicenter pediatric study in the treatment of acute respiratory tract diseases with the aid of a new specific compound, erdosteine (IPSE, Italian Pediatric Study Erdosteine). International journal of clinical pharmacology and therapeutics, 2000, Volume: 38, Issue:8 Topics: Administration, Oral; Anti-Bacterial Agents; Child, Preschool; Double-Blind Method; Drug Therapy, Combination; Expectorants; Female; Fever; Humans; Infant; Male; Respiratory Tract Diseases; Thioglycolates; Thiophenes; Treatment Outcome	2000
HPLC with on-line mass spectrometry detection application to elucidate erdosteine metabolism: preliminary study. International journal of clinical pharmacology and therapeutics, 2000, Volume: 38, Issue:8 Topics: Chromatography, High Pressure Liquid; Expectorants; Female; Humans; Male; Mass Spectrometry; Middle Aged; Thioglycolates; Thiophenes	2000
The effect of long-term treatment with erdosteine on chronic obstructive pulmonary disease: the EQUALIFE Study. Drugs under experimental and clinical research, 2004, Volume: 30, Issue:4 Topics: Administration, Oral; Aged; Capsules; Drug Administration Schedule; Economics, Pharmaceutical; Exercise Test; Female; Humans; Italy; Male; Patient Selection; Pulmonary Disease, Chronic Obstructive; Quality of Life; Spirometry; Surveys and Questionnaires; Thioglycolates; Thiophenes; Time Factors; Treatment Outcome	2004
Effects of erdosteine on smoking-induced lipid peroxidation in healthy smokers. Drugs in R&D, 2005, Volume: 6, Issue:2 Topics: Adult; Female; Humans; Lipid Peroxidation; Male; Nitrates; Nitrites; Smoking; Thiobarbituric Acid Reactive Substances; Thioglycolates; Thiophenes	2005
Clinical effects of erdosteine in the treatment of acute respiratory tract diseases in children. International journal of clinical pharmacology and therapeutics, 2007, Volume: 45, Issue:1 Topics: Acute Disease; Adolescent; Amoxicillin; Anti-Bacterial Agents; Body Temperature; Child; Child, Preschool; Cough; Double-Blind Method; Drug Combinations; Drug Therapy, Combination; Expectorants; Female; Humans; Italy; Male; Respiratory Sounds; Respiratory Tract Infections; Romania; Severity of Illness Index; Thioglycolates; Thiophenes; Time Factors; Treatment Outcome	2007
Changes in blood ROS, e-NO, and some pro-inflammatory mediators in bronchial secretions following erdosteine or placebo: a controlled study in current smokers with mild COPD. Pulmonary pharmacology & therapeutics, 2008, Volume: 21, Issue:2 Topics: Aged; Analysis of Variance; Antioxidants; Breath Tests; Bronchi; Cytokines; Dinoprost; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Interleukin-6; Interleukin-8; Male; Middle Aged; Nitric Oxide; Pulmonary Disease, Chronic Obstructive; Reactive Oxygen Species; Smoking; Thioglycolates; Thiophenes; Time Factors; Tumor Necrosis Factor-alpha	2008
Effectiveness of erdosteine in elderly patients with bronchiectasis and hypersecretion: a 15-day, prospective, parallel, open-label, pilot study. Clinical therapeutics, 2007, Volume: 29, Issue:9 Topics: Administration, Oral; Aged; Bronchiectasis; Chronic Disease; Combined Modality Therapy; Expectorants; Female; Forced Expiratory Volume; Humans; Male; Mucus; Physical Therapy Modalities; Pilot Projects; Prospective Studies; Respiratory System; Thioglycolates; Thiophenes	2007
Erdosteine enhances airway response to salbutamol in patients with mild-to-moderate COPD. Therapeutic advances in respiratory disease, 2008, Volume: 2, Issue:5 Topics: Adrenergic beta-Agonists; Aged; Albuterol; Bronchi; Drug Synergism; Expectorants; Female; Forced Expiratory Volume; Humans; Lipid Peroxidation; Male; Middle Aged; Oxidative Stress; Pulmonary Disease, Chronic Obstructive; Reactive Oxygen Species; Thioglycolates; Thiophenes	2008
Effectiveness of erdosteine, a second generation mucolytic agent, in children with acute rhinosinusitis: a randomized, placebo controlled, double-blinded clinical study. Acta paediatrica (Oslo, Norway : 1992), 2010, Volume: 99, Issue:4 Topics: Acute Disease; Anti-Bacterial Agents; Bacterial Infections; Child; Double-Blind Method; Drug Therapy, Combination; Expectorants; Female; Humans; Male; Placebos; Rhinitis; Sinusitis; Thioglycolates; Thiophenes	2010
Effect of the mucolytic erdosteine on the success rate of PPI-based first-line triple therapy for Helicobacter pylori eradication: a prospective, double-blind, randomized, placebo-controlled study. Scandinavian journal of gastroenterology, 2010, Volume: 45, Issue:6 Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Administration, Oral; Adult; Amoxicillin; Biopsy; Clarithromycin; Double-Blind Method; Drug Therapy, Combination; Endoscopy, Gastrointestinal; Expectorants; Female; Follow-Up Studies; Gastric Mucosa; Gastritis; Helicobacter Infections; Helicobacter pylori; Humans; Male; Pantoprazole; Prospective Studies; Proton Pump Inhibitors; Thioglycolates; Thiophenes; Treatment Outcome	2010
Erdosteine affects eicosanoid production in COPD. International journal of clinical pharmacology and therapeutics, 2011, Volume: 49, Issue:1 Topics: Aged; Antioxidants; Double-Blind Method; Eicosanoids; Female; Forced Expiratory Volume; Humans; Leukotriene B4; Leukotriene E4; Male; Middle Aged; Pulmonary Disease, Chronic Obstructive; Reactive Oxygen Species; Thioglycolates; Thiophenes	2011
Efficacy and safety of erdosteine in the treatment of chronic rhinosinusitis with nasal polyposis - a pilot study. Rhinology, 2013, Volume: 51, Issue:4 Topics: Adult; Aged; Anti-Inflammatory Agents; Chronic Disease; Drug Therapy, Combination; Expectorants; Female; Humans; Male; Middle Aged; Mometasone Furoate; Nasal Polyps; Pilot Projects; Pregnadienediols; Prospective Studies; Rhinitis; Sinusitis; Thioglycolates; Thiophenes; Treatment Outcome; Young Adult	2013
CD8 and CD4 epitope predictions in RV144: no strong evidence of a T-cell driven sieve effect in HIV-1 breakthrough sequences from trial participants. PloS one, 2014, Volume: 9, Issue:10 Topics: Adolescent; Adult; AIDS Vaccines; Alleles; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Epitopes, T-Lymphocyte; Female; gag Gene Products, Human Immunodeficiency Virus; Genotype; HIV Envelope Protein gp120; HIV Infections; HIV-1; HLA Antigens; Humans; Male; Proteome; Thioglycolates; Thiophenes; Young Adult	2014
Efficacy of erdosteine 900 versus 600 mg/day in reducing oxidative stress in patients with COPD exacerbations: Results of a double blind, placebo-controlled trial. Pulmonary pharmacology & therapeutics, 2015, Volume: 33 Topics: Administration, Oral; Adult; Aged; Albuterol; Antioxidants; Bronchodilator Agents; Dose-Response Relationship, Drug; Double-Blind Method; Expectorants; Female; Follow-Up Studies; Forced Expiratory Volume; Humans; Inflammation; Male; Middle Aged; Oxidative Stress; Pulmonary Disease, Chronic Obstructive; Reactive Oxygen Species; Thioglycolates; Thiophenes	2015
Erdosteine reduces inflammation and time to first exacerbation postdischarge in hospitalized patients with AECOPD. International journal of chronic obstructive pulmonary disease, 2015, Volume: 10 Topics: Adult; Aged; Anti-Inflammatory Agents; Biomarkers; C-Reactive Protein; Disease Progression; Drug Administration Schedule; Expectorants; Female; Forced Expiratory Volume; Humans; Inflammation Mediators; Italy; Lung; Male; Middle Aged; Patient Discharge; Prospective Studies; Pulmonary Disease, Chronic Obstructive; Recovery of Function; Recurrence; Single-Blind Method; Thioglycolates; Thiophenes; Time Factors; Treatment Outcome	2015
Erdosteine reduces the exercise-induced oxidative stress in patients with severe COPD: Results of a placebo-controlled trial. Pulmonary pharmacology & therapeutics, 2016, Volume: 41 Topics: Aged; Anti-Inflammatory Agents; Antioxidants; Double-Blind Method; Exercise; Exercise Test; Expectorants; Female; Humans; Inflammation Mediators; Male; Oxidative Stress; Pulmonary Disease, Chronic Obstructive; Reactive Oxygen Species; Severity of Illness Index; Thioglycolates; Thiophenes	2016
Effect of erdosteine on the rate and duration of COPD exacerbations: the RESTORE study. The European respiratory journal, 2017, Volume: 50, Issue:4 Topics: Aged; Dose-Response Relationship, Drug; Double-Blind Method; Drug Monitoring; Expectorants; Female; Forced Expiratory Volume; Humans; Male; Middle Aged; Pulmonary Disease, Chronic Obstructive; Quality of Life; Severity of Illness Index; Symptom Flare Up; Thioglycolates; Thiophenes; Treatment Outcome	2017
Effect of Erdosteine on COPD Exacerbations in COPD Patients with Moderate Airflow Limitation. International journal of chronic obstructive pulmonary disease, 2019, Volume: 14 Topics: Adult; Aged; Aged, 80 and over; Antioxidants; Disease Progression; Double-Blind Method; Europe; Expectorants; Female; Forced Expiratory Volume; Humans; Lung; Male; Middle Aged; Pulmonary Disease, Chronic Obstructive; Recovery of Function; Severity of Illness Index; Thioglycolates; Thiophenes; Time Factors; Treatment Outcome	2019
Reducing exacerbations in children and adults with primary ciliary dyskinesia using erdosteine and/or azithromycin therapy (REPEAT trial): study protocol for a multicentre, double-blind, double-dummy, 2×2 partial factorial, randomised controlled trial. BMJ open respiratory research, 2022, Volume: 9, Issue:1 Topics: Adult; Australia; Azithromycin; Child; Ciliary Motility Disorders; Humans; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Thioglycolates; Thiophenes	2022

Other Studies

112 other study(ies) available for erdosteine and thiophenes

Article	Year
Erdosteine protection from cigarette smoke-induced loss of alpha 1-antitrypsin activity in rat lungs. International journal of clinical pharmacology, therapy, and toxicology, 1989, Volume: 27, Issue:5 Topics: alpha 1-Antitrypsin; Animals; Bronchoalveolar Lavage Fluid; Lung; Male; Rats; Rats, Inbred Strains; Smoking; Thioglycolates; Thiophenes	1989
In vitro protection by erdosteine against oxidative inactivation of alpha-1-antitrypsin by cigarette smoke. Respiration; international review of thoracic diseases, 1989, Volume: 55, Issue:2 Topics: alpha 1-Antitrypsin; Ascorbic Acid; Free Radicals; Glutathione; Humans; In Vitro Techniques; Nicotiana; Plants, Toxic; Smoke; Thioglycolates; Thiophenes	1989
Effect of erdosteine and its metabolites on tracheobronchial mucus production and transport. Drugs under experimental and clinical research, 1988, Volume: 14, Issue:11 Topics: Administration, Oral; Animals; Bronchi; Columbidae; Expectorants; Injections, Intravenous; Lethal Dose 50; Male; Mice; Mucociliary Clearance; Mucus; Rabbits; Thioglycolates; Thiophenes; Trachea	1988
DL-S-(2-[N-3-(2-oxo-tetrahydrothienyl)acetamido])-thioglycolic acid: a novel mucolytic agent of the class of homocysteine thiolactone derivatives. Il Farmaco; edizione scientifica, 1986, Volume: 41, Issue:1 Topics: Animals; Chemical Phenomena; Chemistry; Expectorants; Magnetic Resonance Spectroscopy; Male; Rabbits; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Thioglycolates; Thiophenes; Viscosity	1986
Synthesis and free radical scavenging properties of the enantiomers of erdosteine. Farmaco (Societa chimica italiana : 1989), 1994, Volume: 40, Issue:11 Topics: Animals; Behavior, Animal; Body Weight; Female; Free Radical Scavengers; Lung; Male; Mice; Paraquat; Stereoisomerism; Thioglycolates; Thiophenes	1994
High-performance liquid chromatographic determination of erdosteine and its optical active metabolite utilizing a fluorescent chiral tagging reagent, R-(-)-4-(N,N-dimethylamiosulfonyl)-7-(3-aminopyrrolidin-1-yl)-2 ,1,3-benzoxadiazole. Journal of chromatography. B, Biomedical sciences and applications, 1998, Nov-20, Volume: 719, Issue:1-2 Topics: Animals; Chromatography, High Pressure Liquid; Fluorescent Dyes; Oxadiazoles; Rats; Spectrometry, Fluorescence; Stereoisomerism; Sulfonamides; Thioglycolates; Thiophenes	1998
Erdosteine enhances mucociliary clearance in rats with and without airway inflammation. Journal of pharmacological and toxicological methods, 1998, Volume: 40, Issue:3 Topics: Albumins; Ambroxol; Animals; Bronchi; Bronchitis; Bronchoalveolar Lavage Fluid; Carbocysteine; Carbon; Expectorants; Glycosaminoglycans; Lipopolysaccharides; Male; Mucociliary Clearance; Particle Size; Rats; Rats, Wistar; Thioglycolates; Thiophenes; Time Factors	1998
Effects of erdosteine and its metabolites on bacterial adhesiveness. Arzneimittel-Forschung, 1999, Volume: 49, Issue:4 Topics: Animals; Bacterial Adhesion; Escherichia coli; Expectorants; Guinea Pigs; Hemagglutination; Humans; In Vitro Techniques; Microscopy, Electron, Scanning; Mouth Mucosa; Staphylococcus aureus; Thioglycolates; Thiophenes	1999
The effect of erdosteine and its active metabolite on reactive oxygen species production by inflammatory cells. Inflammation research : official journal of the European Histamine Research Society ... [et al.], 1999, Volume: 48, Issue:4 Topics: Animals; Anti-Inflammatory Agents; Dose-Response Relationship, Drug; Eosinophils; Expectorants; Guinea Pigs; Humans; Male; Neutrophils; Peritoneal Lavage; Rats; Rats, Wistar; Reactive Oxygen Species; Tetradecanoylphorbol Acetate; Thioglycolates; Thiophenes	1999
Mucolytic and antitussive effects of erdosteine. The Journal of pharmacy and pharmacology, 1999, Volume: 51, Issue:8 Topics: Animals; Antitussive Agents; Citric Acid; Cough; Drug Interactions; Expectorants; Female; Male; Mucociliary Clearance; Mucus; Physical Stimulation; Quail; Rats; Stimulation, Chemical; Swine; Thioglycolates; Thiophenes; Time Factors; Viscosity	1999
Assessment of the antioxidant activity of the SH metabolite I of erdosteine on human neutrophil oxidative bursts. Arzneimittel-Forschung, 2000, Volume: 50, Issue:8 Topics: Acetylglucosamine; Antioxidants; Cell-Free System; Free Radical Scavengers; Humans; Hydrogen Peroxide; Luminescent Measurements; Luminol; Neutrophils; Respiratory Burst; Thioglycolates; Thiophenes; Xanthine Oxidase	2000
Protective effect of erdosteine against hypochlorous acid-induced acute lung injury and lipopolysaccharide-induced neutrophilic lung inflammation in mice. The Journal of pharmacy and pharmacology, 2000, Volume: 52, Issue:11 Topics: Administration, Oral; Animals; Bronchitis; Bronchoalveolar Lavage Fluid; Chronic Disease; Disease Models, Animal; Expectorants; Hypochlorous Acid; Inflammation; Lipopolysaccharides; Lung; Male; Mice; Mice, Inbred BALB C; Reactive Oxygen Species; Thioglycolates; Thiophenes; Tumor Necrosis Factor-alpha	2000
Effects on the reactive oxygen species of erdosteine and its metabolite in vitro. Arzneimittel-Forschung, 2002, Volume: 52, Issue:6 Topics: Acetylcysteine; Antioxidants; Glutathione; Hydrogen Peroxide; Hypochlorous Acid; Kinetics; Reactive Oxygen Species; Superoxides; Thioglycolates; Thiophenes	2002
The combination of the SH metabolite of erdosteine (a mucoactive drug) and ciprofloxacin increases the inhibition of bacterial adhesiveness achieved by ciprofloxacin alone. Drugs under experimental and clinical research, 2002, Volume: 28, Issue:2-3 Topics: Anti-Infective Agents; Bacterial Adhesion; Ciprofloxacin; Drug Synergism; Epithelial Cells; Escherichia coli; Expectorants; Humans; Microbial Sensitivity Tests; Microscopy, Electron, Scanning; Staphylococcus aureus; Thioglycolates; Thiophenes	2002
The SH-metabolite I of erdosteine, a mucolytic drug, enhances the inhibitory effect of salbutamol on the respiratory burst of neutrophils. Drugs under experimental and clinical research, 2002, Volume: 28, Issue:4 Topics: Albuterol; Drug Synergism; Expectorants; Humans; Neutrophils; Respiratory Burst; Thioglycolates; Thiophenes	2002
Oral erdosteine administration attenuates cisplatin-induced renal tubular damage in rats. Pharmacological research, 2003, Volume: 47, Issue:2 Topics: Acute Kidney Injury; Animals; Antineoplastic Agents; Catalase; Cisplatin; Creatinine; Female; Free Radical Scavengers; Glutathione Peroxidase; Kidney; Kidney Function Tests; Kidney Tubular Necrosis, Acute; Kidney Tubules; Malondialdehyde; Nitric Oxide; Rats; Rats, Wistar; Superoxide Dismutase; Thioglycolates; Thiophenes	2003
Effects of erdosteine treatment against doxorubicin-induced toxicity through erythrocyte and plasma oxidant/antioxidant status in rats. Pharmacological research, 2003, Volume: 47, Issue:4 Topics: Animals; Antibiotics, Antineoplastic; Catalase; Doxorubicin; Erythrocytes; Glutathione Peroxidase; Lipid Peroxidation; Male; Nitric Oxide; Oxidative Stress; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Thioglycolates; Thiophenes; Xanthine Oxidase	2003
Depressant effects of ambroxol and erdosteine on cytokine synthesis, granule enzyme release, and free radical production in rat alveolar macrophages activated by lipopolysaccharide. Pharmacology & toxicology, 2003, Volume: 92, Issue:4 Topics: Ambroxol; Animals; Antioxidants; Cytokines; Cytoplasmic Granules; Expectorants; Free Radical Scavengers; Free Radicals; Hydrogen Peroxide; In Vitro Techniques; Lipopolysaccharides; Macrophages, Alveolar; Nitric Oxide; Rats; Rats, Sprague-Dawley; Superoxides; Thioglycolates; Thiophenes	2003
Erdosteine prevents doxorubicin-induced cardiotoxicity in rats. Pharmacological research, 2003, Volume: 48, Issue:4 Topics: Administration, Oral; Animals; Aspartate Aminotransferases; Blood Pressure; Body Weight; Creatine Kinase; Doxorubicin; Drug Administration Schedule; Heart Diseases; Heart Rate; Humans; Injections, Intraperitoneal; L-Lactate Dehydrogenase; Male; Myocardium; Organ Size; Peroxidase; Rats; Rats, Sprague-Dawley; Thioglycolates; Thiophenes; Turkey	2003
The activities of tissue xanthine oxidase and adenosine deaminase and the levels of hydroxyproline and nitric oxide in rat hearts subjected to doxorubicin: protective effect of erdosteine. Toxicology, 2003, Sep-30, Volume: 191, Issue:2-3 Topics: Adenosine Deaminase; Animals; Antibiotics, Antineoplastic; Antioxidants; Cardiomyopathies; Doxorubicin; Hydroxyproline; Male; Nitric Oxide; Random Allocation; Rats; Rats, Sprague-Dawley; Thioglycolates; Thiophenes; Xanthine Oxidase	2003
Sensitive determination of erdosteine in human plasma by use of automated 96-well solid-phase extraction and LC-MS/MS. Journal of pharmaceutical and biomedical analysis, 2004, Feb-18, Volume: 34, Issue:3 Topics: Adult; Chromatography, Liquid; Humans; Male; Mass Spectrometry; Thioglycolates; Thiophenes	2004
Inhibitory effects of metabolite I of erdosteine on the generation of nitric oxide and peroxynitrite chemiluminescence by human neutrophils. Pharmacology, 2004, Volume: 71, Issue:3 Topics: Adult; Expectorants; Humans; In Vitro Techniques; Indicators and Reagents; Luminescent Measurements; Luminol; Neutrophils; Nitric Oxide; Peroxynitrous Acid; Respiratory Burst; Thioglycolates; Thiophenes	2004
Erdosteine prevents bleomycin-induced pulmonary fibrosis in rats. European journal of pharmacology, 2004, Jun-28, Volume: 494, Issue:2-3 Topics: Animals; Antibiotics, Antineoplastic; Antioxidants; Bleomycin; Glutathione Peroxidase; Hydroxyproline; Lung; Male; Malondialdehyde; Oxidative Stress; Peroxidase; Pulmonary Fibrosis; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Thioglycolates; Thiophenes; Vitamin E	2004
The effects of erdosteine on the activities of some metabolic enzymes during cisplatin-induced nephrotoxicity in rats. Pharmacological research, 2004, Volume: 50, Issue:3 Topics: Animals; Cisplatin; Glucosephosphate Dehydrogenase; Kidney; Malate Dehydrogenase; Rats; Renal Insufficiency; Thioglycolates; Thiophenes	2004
Erdosteine ameliorates neurological outcome and oxidative stress due to ischemia/reperfusion injury in rabbit spinal cord. European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, 2004, Volume: 28, Issue:4 Topics: Adenosine Deaminase; Animals; Aorta, Abdominal; Biomarkers; Disease Models, Animal; Expectorants; Glutathione Peroxidase; Malondialdehyde; Models, Cardiovascular; Motor Neurons; Neuroprotective Agents; Nitric Oxide; Oxidative Stress; Psychomotor Performance; Rabbits; Reperfusion Injury; Spinal Cord; Spinal Cord Ischemia; Superoxide Dismutase; Thioglycolates; Thiophenes; Treatment Outcome; Xanthine Oxidase	2004
Effects of aminoguanidine and antioxidant erdosteine on bleomycin-induced lung fibrosis in rats. Nitric oxide : biology and chemistry, 2004, Volume: 11, Issue:2 Topics: Animals; Antioxidants; Bleomycin; Drug Therapy, Combination; Glutathione Peroxidase; Guanidines; Male; Malondialdehyde; Nitric Oxide; Peroxidase; Pulmonary Fibrosis; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Thioglycolates; Thiophenes; Tyrosine	2004
The protective effect of erdosteine against ototoxicity induced by cisplatin in rats. European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2005, Volume: 262, Issue:10 Topics: Animals; Antineoplastic Agents; Antioxidants; Cisplatin; Female; Hearing Loss; Malondialdehyde; Nitric Oxide; Otoacoustic Emissions, Spontaneous; Random Allocation; Rats; Rats, Wistar; Reactive Oxygen Species; Superoxide Dismutase; Thioglycolates; Thiophenes; Xanthine Oxidase	2005
A combination of budesonide and the SH-metabolite I of erdosteine acts synergistically in reducing chemiluminescence during human neutrophil respiratory burst. Pharmacology, 2005, Volume: 74, Issue:3 Topics: Anti-Inflammatory Agents; Budesonide; Dose-Response Relationship, Drug; Drug Synergism; Humans; In Vitro Techniques; Luminescence; Neutrophils; Respiratory Burst; Thioglycolates; Thiophenes	2005
Erdosteine ameliorates PTZ-induced oxidative stress in mice seizure model. Brain research bulletin, 2005, May-30, Volume: 65, Issue:6 Topics: Animals; Anticonvulsants; Brain Chemistry; Cerebral Cortex; Convulsants; Disease Models, Animal; Drug Interactions; Female; Malondialdehyde; Mice; Nitric Oxide; Oxidative Stress; Pentylenetetrazole; Reaction Time; Seizures; Superoxide Dismutase; Thioglycolates; Thiophenes; Xanthine Oxidase	2005
Attenuation of bleomycin-induced lung fibrosis by oral sulfhydryl containing antioxidants in rats: erdosteine and N-acetylcysteine. Pulmonary pharmacology & therapeutics, 2005, Volume: 18, Issue:5 Topics: Acetylcysteine; Animals; Antioxidants; Bleomycin; Disease Models, Animal; Drug Interactions; Male; Pulmonary Fibrosis; Rats; Rats, Sprague-Dawley; Sulfhydryl Compounds; Thioglycolates; Thiophenes	2005
Protective effects of erdosteine on rotenone-induced oxidant injury in liver tissue. Toxicology and industrial health, 2004, Volume: 20, Issue:6-10 Topics: Animals; Chemical and Drug Induced Liver Injury; Free Radical Scavengers; Insecticides; Lipid Peroxidation; Liver; Male; Oxidative Stress; Rats; Rats, Wistar; Rotenone; Thioglycolates; Thiophenes	2004
In vivo evidences suggesting the role of oxidative stress in pathogenesis of vancomycin-induced nephrotoxicity: protection by erdosteine. Toxicology, 2005, Nov-15, Volume: 215, Issue:3 Topics: Acetylglucosaminidase; Administration, Oral; Animals; Anti-Bacterial Agents; Catalase; Disease Models, Animal; Drug Antagonism; Drug Therapy, Combination; Injections, Intraperitoneal; Kidney; Kidney Diseases; Kidney Tubules; Male; Malondialdehyde; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species; Superoxide Dismutase; Thioglycolates; Thiophenes; Vancomycin	2005
The effects of isoniazid on hippocampal NMDA receptors: protective role of erdosteine. Molecular and cellular biochemistry, 2005, Volume: 277, Issue:1-2 Topics: Animals; Antioxidants; Antitubercular Agents; Hippocampus; Isoniazid; Lipid Peroxidation; Male; Malondialdehyde; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Thioglycolates; Thiophenes	2005
Protective agent, erdosteine, against cisplatin-induced hepatic oxidant injury in rats. Molecular and cellular biochemistry, 2005, Volume: 278, Issue:1-2 Topics: Animals; Antioxidants; Catalase; Cisplatin; Free Radical Scavengers; Glutathione Peroxidase; Liver; Male; Malondialdehyde; Microscopy, Polarization; Nitric Oxide; Oxidants; Random Allocation; Rats; Rats, Wistar; Superoxide Dismutase; Thioglycolates; Thiophenes	2005
The protective role of erdosteine on testicular tissue after testicular torsion and detorsion. Molecular and cellular biochemistry, 2005, Volume: 280, Issue:1-2 Topics: Animals; Catalase; Glutathione Peroxidase; Male; Malondialdehyde; Nitric Oxide; Protective Agents; Rats; Rats, Wistar; Seminiferous Tubules; Spermatic Cord Torsion; Thioglycolates; Thiophenes; Xanthine Oxidase	2005
Effects of erdosteine on bleomycin-induced lung fibrosis in rats. Molecular and cellular biochemistry, 2006, Volume: 281, Issue:1-2 Topics: Acute Lung Injury; Animals; Biomarkers; Bleomycin; Bronchoalveolar Lavage Fluid; Male; Oxidative Stress; Pulmonary Fibrosis; Rats; Rats, Sprague-Dawley; Thioglycolates; Thiophenes	2006
The effects of erdosteine, N-acetylcysteine, and vitamin E on nicotine-induced apoptosis of pulmonary cells. Toxicology, 2006, Feb-15, Volume: 219, Issue:1-3 Topics: Acetylcysteine; Animals; Antioxidants; Apoptosis; Bronchoalveolar Lavage Fluid; Epithelial Cells; Expectorants; Lung; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Peroxidase; Rats; Rats, Wistar; Thioglycolates; Thiophenes; Tumor Necrosis Factor-alpha; Vitamin E	2006
Protein oxidation and lipid peroxidation after renal ischemia-reperfusion injury: protective effects of erdosteine and N-acetylcysteine. Urological research, 2006, Volume: 34, Issue:1 Topics: Acetylcysteine; Animals; Free Radical Scavengers; Kidney Diseases; Kidney Tubules; Lipid Peroxidation; Male; Oxidation-Reduction; Oxidative Stress; Proteins; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Thioglycolates; Thiophenes	2006
Erdosteine against acetaminophen induced renal toxicity. Molecular and cellular biochemistry, 2006, Volume: 287, Issue:1-2 Topics: Acetaminophen; Animals; Drug Evaluation, Preclinical; Female; Kidney; Kidney Cortex; Kidney Diseases; Kidney Tubules, Proximal; Lipid Peroxidation; Nitric Oxide; Rats; Rats, Wistar; Thioglycolates; Thiophenes	2006
Hypobaric-hypoxia-induced pulmonary damage in rats ameliorated by antioxidant erdosteine. Acta histochemica, 2006, Volume: 108, Issue:1 Topics: Animals; Antibodies, Monoclonal; Antioxidants; Atmosphere Exposure Chambers; Atmospheric Pressure; Endothelial Cells; Hematocrit; Hemorrhage; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Hypoxia; Immunohistochemistry; Lung; Malondialdehyde; Pulmonary Artery; Random Allocation; Rats; Thioglycolates; Thiophenes	2006
Protective role of erdosteine on vancomycin-induced oxidative stress in rat liver. Molecular and cellular biochemistry, 2006, Volume: 291, Issue:1-2 Topics: Animals; Anti-Bacterial Agents; Catalase; Expectorants; Injections, Intraperitoneal; Liver; Male; Malondialdehyde; Oxidative Stress; Protective Agents; Rats; Rats, Wistar; Superoxide Dismutase; Thioglycolates; Thiophenes; Vancomycin	2006
Effect of metabolite I of erdosteine on the release of human neutrophil elastase. Pharmacology, 2006, Volume: 77, Issue:3 Topics: Adult; Anti-Inflammatory Agents; Cells, Cultured; Humans; Leukocyte Elastase; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Thioglycolates; Thiophenes	2006
Protective effects of N-acetylcysteine and erdosteine on hemorrhagic shock-induced acute lung injury. European journal of emergency medicine : official journal of the European Society for Emergency Medicine, 2006, Volume: 13, Issue:5 Topics: Acetylcysteine; Animals; Blood Pressure; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Free Radical Scavengers; Glutathione; Lung; Macrophages, Alveolar; Male; Malondialdehyde; Neutrophils; Premedication; Random Allocation; Rats; Rats, Wistar; Respiratory Distress Syndrome; Shock, Hemorrhagic; Thioglycolates; Thiophenes	2006
Regulation of sepsis-induced apoptosis of pulmonary cells by posttreatment of erdosteine and N-aceylcysteine. Toxicology, 2006, Dec-07, Volume: 228, Issue:2-3 Topics: Acetylcysteine; Animals; Apoptosis; Bronchoalveolar Lavage Fluid; Epithelial Cells; Free Radical Scavengers; Immunohistochemistry; In Situ Nick-End Labeling; Lipopolysaccharides; Lung; Peroxidase; Pneumonia; Rats; Rats, Wistar; Sepsis; Thioglycolates; Thiophenes; Tissue Embedding; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A	2006
Erdosteine treatment attenuates oxidative stress and fibrosis in experimental biliary obstruction. Pediatric surgery international, 2007, Volume: 23, Issue:3 Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Cytokines; Expectorants; Glutathione; L-Lactate Dehydrogenase; Liver; Liver Cirrhosis, Biliary; Liver Cirrhosis, Experimental; Male; Malondialdehyde; Microbial Collagenase; Oxidative Stress; Peroxidase; Rats; Thioglycolates; Thiophenes	2007
Protective effects of erdosteine on doxorubicin-induced hepatotoxicity in rats. Archives of medical research, 2007, Volume: 38, Issue:4 Topics: Animals; Antibiotics, Antineoplastic; Antioxidants; Chemical and Drug Induced Liver Injury; Doxorubicin; Lipid Peroxidation; Liver; Liver Diseases; Male; Rats; Rats, Sprague-Dawley; Thioglycolates; Thiophenes	2007
Erdosteine prevents colonic inflammation through its antioxidant and free radical scavenging activities. Digestive diseases and sciences, 2007, Volume: 52, Issue:9 Topics: Acridines; Animals; Antioxidants; Colitis; Collagen; Colon; Disease Models, Animal; DNA Fragmentation; Enzyme-Linked Immunosorbent Assay; Expectorants; Female; Free Radical Scavengers; Glutathione; Luminescence; Luminol; Malondialdehyde; Oxidative Stress; Peroxidase; Rats; Rats, Sprague-Dawley; Severity of Illness Index; Thioglycolates; Thiophenes; Trinitrobenzenesulfonic Acid	2007
The effects of erdosteine on lung injury induced by the ischemia-reperfusion of the hind-limbs in rats. The Journal of surgical research, 2008, Volume: 145, Issue:2 Topics: Adenosine Deaminase; Animals; Antioxidants; Bronchoalveolar Lavage Fluid; Hindlimb; Male; Neutrophils; Nitric Oxide; Oxidative Stress; Peroxidase; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Respiratory Distress Syndrome; Thioglycolates; Thiophenes; Xanthine Oxidase	2008
The protective effect of erdosteine against cyclosporine A-induced cardiotoxicity in rats. Toxicology, 2007, Sep-24, Volume: 239, Issue:1-2 Topics: Animals; Catalase; Chemoprevention; Cyclosporine; Disease Models, Animal; Expectorants; Fibrosis; Glutathione Peroxidase; Heart; Heart Diseases; Immunosuppressive Agents; Male; Malondialdehyde; Myocardium; Nitric Oxide; Oxidative Stress; Protein Carbonylation; Rats; Rats, Wistar; Superoxide Dismutase; Thioglycolates; Thiophenes	2007
Protective effects of erdosteine and vitamins C and E combination on ischemia-reperfusion-induced lung oxidative stress and plasma copper and zinc levels in a rat hind limb model. Biological trace element research, 2007, Volume: 118, Issue:1 Topics: Animals; Antioxidants; Ascorbic Acid; Copper; Creatine Kinase; Expectorants; Glutathione; L-Lactate Dehydrogenase; Lower Extremity; Lung; Male; Malondialdehyde; Oxidative Stress; Protective Agents; Random Allocation; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Thioglycolates; Thiophenes; Vitamin E; Zinc	2007
Renoprotective effect of erdosteine in rats against gentamicin nephrotoxicity: a comparison of 99mTc-DMSA uptake with biochemical studies. Molecular and cellular biochemistry, 2008, Volume: 308, Issue:1-2 Topics: Animals; Antioxidants; Blood Urea Nitrogen; Creatinine; Gentamicins; Kidney; Male; Malondialdehyde; Oxidants; Protective Agents; Radionuclide Imaging; Rats; Rats, Wistar; Technetium Tc 99m Dimercaptosuccinic Acid; Thioglycolates; Thiophenes	2008
The effects of erdosteine, N-acetylcysteine, and vitamin E on nicotine-induced apoptosis of hippocampal neural cells. Journal of cellular biochemistry, 2008, Aug-01, Volume: 104, Issue:5 Topics: Acetylcysteine; Animals; Apoptosis; Hippocampus; Neurons; Nicotine; Peroxidase; Rats; Rats, Wistar; Thioglycolates; Thiophenes; Tocopherols; Tumor Necrosis Factor-alpha	2008
Effects of erdosteine on acetaminophen-induced hepatotoxicity in rats. Toxicologic pathology, 2008, Volume: 36, Issue:5 Topics: Acetaminophen; Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Catalase; Dose-Response Relationship, Drug; Drug Interactions; Female; Glutathione Peroxidase; Liver; Malondialdehyde; Necrosis; Nitric Oxide; Oxidants; Rats; Rats, Wistar; Superoxide Dismutase; Thioglycolates; Thiophenes	2008
[Effects of erdosteine on inflammation and fibrosis in rats with pulmonary fibrosis induced by bleomycin]. Tuberkuloz ve toraks, 2008, Volume: 56, Issue:2 Topics: Animals; Bleomycin; Bronchoalveolar Lavage Fluid; Chemokines; Expectorants; Humans; Male; Pulmonary Fibrosis; Random Allocation; Rats; Rats, Wistar; Thioglycolates; Thiophenes	2008
Erdosteine for COPD exacerbations. Drug and therapeutics bulletin, 2008, Volume: 46, Issue:10 Topics: Adult; Anti-Bacterial Agents; Drug Combinations; Expectorants; Humans; Pulmonary Disease, Chronic Obstructive; Randomized Controlled Trials as Topic; Thioglycolates; Thiophenes	2008
The protective effect of erdosteine on short-term global brain ischemia/reperfusion injury in rats. Progress in neuro-psychopharmacology & biological psychiatry, 2009, Feb-01, Volume: 33, Issue:1 Topics: Animals; Antioxidants; Erythrocytes; Male; Nitric Oxide; Rats; Rats, Wistar; Reperfusion Injury; Thiobarbituric Acid Reactive Substances; Thioglycolates; Thiophenes	2009
Protective role of caffeic acid phenethyl ester and erdosteine on activities of purine-catabolizing enzymes and level of nitric oxide in red blood cells of isoniazid-administered rats. Toxicology and industrial health, 2008, Volume: 24, Issue:8 Topics: Adenosine Deaminase; Administration, Oral; Animals; Antioxidants; Antitubercular Agents; Caffeic Acids; Disease Models, Animal; Drinking; Drug Therapy, Combination; Erythrocytes; Injections, Intraperitoneal; Isoniazid; Male; Nitric Oxide; Oxidative Stress; Phenylethyl Alcohol; Purines; Rats; Rats, Wistar; Thioglycolates; Thiophenes; Xanthine Oxidase	2008
Protective effect of sulfhydryl-containing antioxidants against ischemia/reperfusion injury of prepubertal rat intestine. Journal of gastroenterology and hepatology, 2009, Volume: 24, Issue:4 Topics: Acetylcysteine; Animals; Antioxidants; Constriction; Disease Models, Animal; Glutathione Peroxidase; Ileum; Lipid Peroxidation; Male; Malondialdehyde; Mesenteric Artery, Superior; Oxidative Stress; Protein Carbonylation; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Sexual Development; Sulfhydryl Compounds; Superoxide Dismutase; Thioctic Acid; Thioglycolates; Thiophenes	2009
Erdosteine modulates radiocontrast-induced hepatotoxicity in rat. Cell biochemistry and function, 2009, Volume: 27, Issue:3 Topics: Animals; Catalase; Chemical and Drug Induced Liver Injury; Contrast Media; Glutathione; Glutathione Peroxidase; Lipid Peroxidation; Liver; Liver Diseases; Male; Radiopharmaceuticals; Rats; Rats, Wistar; Reactive Oxygen Species; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Thioglycolates; Thiophenes	2009
The protective effect of erdosteine on vancomycin-induced pancreatic damage in rats. Molecular and cellular biochemistry, 2009, Volume: 331, Issue:1-2 Topics: Animals; Male; Pancreas; Protective Agents; Rats; Rats, Wistar; Thioglycolates; Thiophenes; Vancomycin	2009
Erdosteine and ebselen as useful agents in intestinal ischemia/reperfusion injury. The Journal of surgical research, 2009, Volume: 155, Issue:2 Topics: Animals; Antioxidants; Azoles; Biomarkers; Glutathione Peroxidase; Intestinal Mucosa; Intestine, Small; Isoindoles; Male; Malondialdehyde; Models, Animal; Nitrates; Nitrites; Organoselenium Compounds; Oxidative Stress; Protein Carbonylation; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Superoxide Dismutase; Thioglycolates; Thiophenes	2009
[Effects of erdosteine on inflammation and fibrosis in rats with pulmonary fibrosis induced by bleomycin]. Tuberkuloz ve toraks, 2009, Volume: 57, Issue:2 Topics: Animals; Bleomycin; Expectorants; Pulmonary Fibrosis; Rats; Thioglycolates; Thiophenes	2009
Combination antioxidant effect of α-tocoferol and erdosteine in ischemia-reperfusion injury in rat model. International urology and nephrology, 2010, Volume: 42, Issue:3 Topics: alpha-Tocopherol; Animals; Antioxidants; Kidney; Male; Malondialdehyde; Rats; Rats, Wistar; Reactive Oxygen Species; Reperfusion Injury; Superoxide Dismutase; Thioglycolates; Thiophenes; Xanthine Oxidase	2010
Erdosteine in renal ischemia-reperfusion injury: an experimental study in pigs. The Journal of veterinary medical science, 2010, Volume: 72, Issue:1 Topics: Animals; Antioxidants; Free Radical Scavengers; Kidney; Kidney Diseases; Male; Reperfusion Injury; Swine; Swine Diseases; Thioglycolates; Thiophenes	2010
Free radical scavenging activity of erdosteine metabolite I investigated by electron paramagnetic resonance spectroscopy. Pharmacology, 2010, Volume: 85, Issue:4 Topics: Animals; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Humans; Hydrogen Peroxide; Hydroxyl Radical; Iron; Nitroso Compounds; Oxidation-Reduction; Oxidative Stress; Reactive Oxygen Species; Spin Labels; Sulfhydryl Compounds; Thioglycolates; Thiophenes	2010
Beneficial effect of erdosteine on methotrexate-induced testicular toxicity in mice. Toxicology and industrial health, 2010, Volume: 26, Issue:7 Topics: Analysis of Variance; Animals; Drug Interactions; Lipid Peroxidation; Male; Malondialdehyde; Methotrexate; Mice; Oxidative Stress; Peroxidase; Statistics, Nonparametric; Testicular Diseases; Testis; Thioglycolates; Thiophenes	2010
Effects of erdosteine on cyclosporine-A-induced hepatotoxicity in rats. Drug and chemical toxicology, 2011, Volume: 34, Issue:1 Topics: Animals; Antioxidants; Catalase; Chemical and Drug Induced Liver Injury; Cyclosporine; Glutathione Peroxidase; Immunosuppressive Agents; Liver; Liver Function Tests; Male; Malondialdehyde; Nitric Oxide; Oxidative Stress; Rats; Rats, Wistar; Superoxide Dismutase; Thioglycolates; Thiophenes	2011
Comparison of the effects of N-acetyl cysteine and erdosteine in rats with renal injury caused by paracetamol intoxication. Human & experimental toxicology, 2011, Volume: 30, Issue:9 Topics: Acetaminophen; Acetylcysteine; Acute Kidney Injury; Animals; Antioxidants; Data Interpretation, Statistical; Female; Kidney; Kidney Function Tests; Radionuclide Imaging; Rats; Rats, Wistar; Thioglycolates; Thiophenes	2011
Dual effects of erdosteine on hemostasis via its different metabolites in young rats. Human & experimental toxicology, 2011, Volume: 30, Issue:10 Topics: Animals; Expectorants; Hemostasis; International Normalized Ratio; Platelet Count; Prothrombin Time; Rats; Rats, Wistar; Thioglycolates; Thiophenes	2011
Simultaneous estimation of Cefixime and Erdosteine in capsule dosage form by spectrophotometric method. Hindustan antibiotics bulletin, 2009, Volume: 51, Issue:1-4 Topics: Anti-Bacterial Agents; Capsules; Cefixime; Expectorants; Spectrophotometry, Ultraviolet; Thioglycolates; Thiophenes	2009
Prevention of pulmonary complications of pneumoperitoneum in rats. Journal of cardiothoracic surgery, 2011, Feb-08, Volume: 6 Topics: Animals; Carbon Dioxide; Disease Models, Animal; Expectorants; Female; Laparoscopy; Lung Injury; Oxidative Stress; Pneumoperitoneum, Artificial; Rats; Rats, Wistar; Thioglycolates; Thiophenes; Treatment Outcome	2011
Protective effects of erdosteine on amikacin induced visual evoked potentials and lipid peroxidation alterations. Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2011, Volume: 27, Issue:2 Topics: Amikacin; Animals; Anti-Bacterial Agents; Evoked Potentials, Visual; Intravitreal Injections; Lipid Peroxidation; Male; Rats; Rats, Wistar; Thiobarbituric Acid Reactive Substances; Thioglycolates; Thiophenes	2011
The protective effect of erdosteine on radiocontrast induced nephrotoxicity in rats. Environmental toxicology, 2011, Volume: 26, Issue:4 Topics: Animals; Antioxidants; Blood Urea Nitrogen; Contrast Media; Creatinine; Cystatin C; Female; Kidney; Lipocalins; Osteopontin; Oxidants; Oxidative Stress; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; Thioglycolates; Thiophenes; Xenobiotics	2011
Effects of erdosteine on cyclosporin-A-induced nephrotoxicity. Human & experimental toxicology, 2012, Volume: 31, Issue:6 Topics: Animals; Antioxidants; Catalase; Cyclosporine; Glutathione Peroxidase; Immunosuppressive Agents; Kidney; Kidney Diseases; Male; Malondialdehyde; Nitric Oxide; Oxidative Stress; Rats; Rats, Wistar; Superoxide Dismutase; Thioglycolates; Thiophenes	2012
[ Erdosteine (Mucodox), oral administration]. Journal de pharmacie de Belgique, 2011, Issue:2 Topics: Bronchial Diseases; Expectorants; Humans; Pulmonary Disease, Chronic Obstructive; Thioglycolates; Thiophenes	2011
Is intratympanic injection of erdosteine protective against cisplatin-induced ototoxicity? Neurotoxicity research, 2012, Volume: 21, Issue:3 Topics: Animals; Antineoplastic Agents; Auditory Threshold; Cisplatin; Evoked Potentials, Auditory, Brain Stem; Expectorants; Guinea Pigs; Hair Cells, Auditory, Outer; Hearing Loss; Injections; Microscopy, Electron, Scanning; Neuroprotective Agents; Round Window, Ear; Thioglycolates; Thiophenes; Treatment Failure; Tympanic Membrane	2012
Effects of erdosteine on hemostasis: an experimental study. Human & experimental toxicology, 2012, Volume: 31, Issue:6 Topics: Animals; Blood Coagulation; Blood Platelets; Expectorants; Hemostasis; International Normalized Ratio; Male; Partial Thromboplastin Time; Platelet Count; Prothrombin Time; Rats; Rats, Wistar; Thioglycolates; Thiophenes	2012
Protective effect of erdosteine against cisplatin-induced ototoxicity in a guinea pig model. Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2012, Volume: 146, Issue:4 Topics: Animals; Cisplatin; Ear Diseases; Female; Guinea Pigs; Injections, Intraperitoneal; Microscopy, Electron, Scanning; Prospective Studies; Statistics, Nonparametric; Thioglycolates; Thiophenes	2012
Protective effect of erdosteine metabolite I against hydrogen peroxide-induced oxidative DNA-damage in lung epithelial cells. Arzneimittel-Forschung, 2011, Volume: 61, Issue:12 Topics: Antioxidants; Cell Line, Tumor; Cell Survival; Comet Assay; DNA Damage; Epithelial Cells; Humans; Hydrogen Peroxide; Indicators and Reagents; Lung; Oxidants; Oxidative Stress; Reactive Oxygen Species; Thioglycolates; Thiophenes	2011
Severe drug hypersensitivity induced by erdosteine and doxofylline as confirmed by patch and lymphocyte transformation tests: a case report. Journal of investigational allergology & clinical immunology, 2012, Volume: 22, Issue:3 Topics: Adult; Drug Hypersensitivity; Female; Humans; Lymphocyte Activation; Patch Tests; Theophylline; Thioglycolates; Thiophenes	2012
N-Acetyl cysteine and erdosteine treatment in acetaminophen-induced liver damage. Toxicology and industrial health, 2014, Volume: 30, Issue:7 Topics: Acetaminophen; Acetylcysteine; Alanine Transaminase; Animals; Antidotes; Antipyretics; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Female; International Normalized Ratio; Oxidants; Prothrombin Time; Rats; Rats, Wistar; Thioglycolates; Thiophenes	2014
Erdosteine protects rat testis tissue from hypoxic injury by reducing apoptotic cell death. Andrologia, 2014, Volume: 46, Issue:1 Topics: Animals; Apoptosis; Caspase 3; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Male; Rats; Rats, Wistar; Testis; Thioglycolates; Thiophenes	2014
[HPLC determination of the related substances in erdosteine]. Yao xue xue bao = Acta pharmaceutica Sinica, 2012, Volume: 47, Issue:8 Topics: Chromatography, High Pressure Liquid; Drug Contamination; Expectorants; Limit of Detection; Thioglycolates; Thiophenes	2012
[Simultaneous determination of erdosteine and its active metabolite in human plasma by liquid chromatography-tandem mass spectrometry with pre-column derivatization]. Yao xue xue bao = Acta pharmaceutica Sinica, 2013, Volume: 48, Issue:3 Topics: Administration, Oral; Area Under Curve; Chromatography, Liquid; Female; Humans; Male; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Thioglycolates; Thiophenes	2013
Determination of oxidative stress and effect of erdosteine on rhinitis medicamentosa in a rat model. European journal of pharmacology, 2014, Nov-05, Volume: 742 Topics: Animals; Antioxidants; Disease Models, Animal; Male; Nasal Decongestants; Nasal Mucosa; Oxidative Stress; Rats; Rats, Wistar; Rhinitis, Vasomotor; Thioglycolates; Thiophenes	2014
Antioxidant effect of erdosteine and lipoic acid in ovarian ischemia-reperfusion injury. European journal of obstetrics, gynecology, and reproductive biology, 2014, Volume: 183 Topics: Animals; Antioxidants; Drug Therapy, Combination; Female; Models, Animal; Ovarian Follicle; Ovary; Oxidative Stress; Rats; Rats, Wistar; Reperfusion Injury; Thioctic Acid; Thioglycolates; Thiophenes; Torsion, Mechanical	2014
Protective effects of erdosteine against nephrotoxicity caused by gamma radiation in male albino rats. Human & experimental toxicology, 2016, Volume: 35, Issue:1 Topics: Animals; Cytokines; Expectorants; Gamma Rays; Gene Expression Regulation; Kidney Diseases; Male; Rats; Thioglycolates; Thiophenes	2016
Protective effects of erdosteine, vitamin E, and vitamin C on renal injury induced by the ischemia-reperfusion of the hind limbs in rats. Turkish journal of medical sciences, 2015, Volume: 45, Issue:1 Topics: Animals; Antioxidants; Ascorbic Acid; Hindlimb; Kidney; Kidney Diseases; Lipid Peroxidation; Male; Oxidoreductases; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Thioglycolates; Thiophenes; Vitamin E	2015
Attenuation of bleomycin induced lung fibrosis by erdosteine and inhibition of the inducible nitric oxide synthase. Bratislavske lekarske listy, 2015, Volume: 116, Issue:3 Topics: Acute Lung Injury; Animals; Bleomycin; Drug Therapy, Combination; Enzyme Inhibitors; Expectorants; Injections, Intraperitoneal; Isothiuronium; Lung; Male; Nitric Oxide Synthase Type II; Pulmonary Fibrosis; Random Allocation; Rats; Rats, Sprague-Dawley; Thioglycolates; Thiophenes; Tumor Necrosis Factor-alpha	2015
Erdosteine protects HEI-OC1 auditory cells from cisplatin toxicity through suppression of inflammatory cytokines and induction of Nrf2 target proteins. Toxicology and applied pharmacology, 2015, Oct-15, Volume: 288, Issue:2 Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Apoptosis Regulatory Proteins; Cell Line; Cisplatin; Cytokines; Cytoprotection; Dose-Response Relationship, Drug; Ear, Inner; Gene Expression Regulation; Inflammation Mediators; Mice; Mitochondria; NF-E2-Related Factor 2; Oxidative Stress; Phosphatidylinositol 3-Kinase; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Reactive Nitrogen Species; Reactive Oxygen Species; RNA Interference; Signal Transduction; Thioglycolates; Thiophenes; Transfection; Tumor Suppressor Protein p53	2015
Investigation of the protective effect of erdosteine against cyclosporine-induced injury in rat liver with histological and biochemical methods. Turkish journal of medical sciences, 2015, Volume: 45, Issue:6 Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Cyclosporine; Expectorants; Glutathione Peroxidase; Immunosuppressive Agents; Liver; Male; Malondialdehyde; Microscopy; Random Allocation; Rats, Wistar; Superoxide Dismutase; Thioglycolates; Thiophenes	2015
Anti-inflammatory Effect of Erdosteine in Lipopolysaccharide-Stimulated RAW 264.7 Cells. Inflammation, 2016, Volume: 39, Issue:4 Topics: Animals; Anti-Inflammatory Agents; I-kappa B Kinase; Lipopolysaccharides; Mice; NF-kappa B; Pre-Exposure Prophylaxis; RAW 264.7 Cells; Thioglycolates; Thiophenes	2016
The impact of erdosteine on cisplatin-induced ototoxicity: a proteomics approach. European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2017, Volume: 274, Issue:3 Topics: Animals; Antineoplastic Agents; Antioxidants; Blotting, Western; Case-Control Studies; Cisplatin; Cochlea; Female; Hearing Loss, Sensorineural; Mass Spectrometry; Proteins; Proteomics; Rats, Sprague-Dawley; Thioglycolates; Thiophenes; Up-Regulation	2017
Pemphigus herpetiformis-type drug reaction caused by erdosteine containing mucolytic in a child. Cutaneous and ocular toxicology, 2017, Volume: 36, Issue:3 Topics: Child; Desmoglein 1; Drug Eruptions; Expectorants; Humans; Immunoglobulin G; Male; Pemphigus; Skin; Thioglycolates; Thiophenes	2017
Protective role of erdosteine pretreatment on oleic acid-induced acute lung injury. The Journal of surgical research, 2017, 06-01, Volume: 213 Topics: Acute Lung Injury; Administration, Oral; Animals; Antioxidants; Biomarkers; Drug Administration Schedule; Expectorants; Macrophages, Alveolar; Male; Neutrophils; Oleic Acid; Protective Agents; Random Allocation; Rats; Rats, Wistar; Thioglycolates; Thiophenes	2017
Acute and Chronic Effects of Oral Erdosteine on Ciliary Beat Frequency, Cough Sensitivity and Airway Reactivity. Advances in experimental medicine and biology, 2018, Volume: 1023 Topics: Administration, Oral; Animals; Cilia; Citric Acid; Cough; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Male; Reflex; Respiratory Hypersensitivity; Thioglycolates; Thiophenes; Trachea	2018
Effects of Erdosteine on Experimental Acute Pancreatitis Model. Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2017, Volume: 27, Issue:10 Topics: Acute Disease; Amylases; Animals; Ceruletide; Disease Models, Animal; Edema; Expectorants; Lipase; Male; Necrosis; Pancreas; Pancreatitis; Rats; Rats, Wistar; Thioglycolates; Thiophenes; Treatment Outcome	2017
Erdosteine ameliorates the harmful effects of ischemia-reperfusion injury on the liver of rats. Acta cirurgica brasileira, 2017, Volume: 32, Issue:10 Topics: Animals; Disease Models, Animal; Female; Liver; Protective Agents; Rats; Rats, Wistar; Reperfusion Injury; Thioglycolates; Thiophenes	2017
Protective effect of erdosteine on erythrocyte deformability in a rat model of lower limb ischemia/reperfusion injury Turkish journal of medical sciences, 2018, Feb-23, Volume: 48, Issue:1 Topics: Animals; Disease Models, Animal; Erythrocyte Deformability; Erythrocytes; Expectorants; Hindlimb; Ischemia; Lower Extremity; Rats, Wistar; Reperfusion Injury; Thioglycolates; Thiophenes	2018
Investigation of Therapeutic Effects of Erdosteine on Polycystic Ovary Syndrome in a Rat Model. Medical principles and practice : international journal of the Kuwait University, Health Science Centre, 2018, Volume: 27, Issue:6 Topics: Analysis of Variance; Animals; Blood Glucose; Cholesterol; Disease Models, Animal; Estrone; Expectorants; Female; Hypoglycemic Agents; Insulin Resistance; Metformin; Ovary; Oxidative Stress; Polycystic Ovary Syndrome; Random Allocation; Rats; Rats, Wistar; Thioglycolates; Thiophenes; Treatment Outcome; Uterus	2018
The effect of erdosteine on airway defence mechanisms and inflammatory cytokines in the settings of allergic inflammation. Pulmonary pharmacology & therapeutics, 2019, Volume: 54 Topics: Animals; Bronchoalveolar Lavage Fluid; Bronchodilator Agents; Cough; Cytokines; Disease Models, Animal; Expectorants; Guinea Pigs; Inflammation; Male; Mucociliary Clearance; Thioglycolates; Thiophenes	2019
Thiol-Based Drugs in Pulmonary Medicine: Much More than Mucolytics. Trends in pharmacological sciences, 2019, Volume: 40, Issue:7 Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Expectorants; Humans; Lung Neoplasms; Pulmonary Medicine; Sulfhydryl Compounds; Thioglycolates; Thiophenes	2019
The influence of erdosteine administration on lead-induced oxidative stress in rat muscle. Drug and chemical toxicology, 2022, Volume: 45, Issue:1 Topics: Animals; Antioxidants; Catalase; Lead; Male; Malondialdehyde; Muscles; Oxidative Stress; Pilot Projects; Rats; Rats, Wistar; Superoxide Dismutase; Thioglycolates; Thiophenes	2022
Protective effects of Erdosteine on interleukin-1β-stimulated inflammation via inhibiting the activation of MAPK, NF-κB, and Wnt/β-catenin signaling pathways in rat osteoarthritis. European journal of pharmacology, 2020, Apr-15, Volume: 873 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; beta Catenin; Cells, Cultured; Chondrocytes; Dose-Response Relationship, Drug; Extracellular Matrix; Inflammation; Injections, Intra-Articular; Interleukin-1beta; Mitogen-Activated Protein Kinases; NF-kappa B; Osteoarthritis; Rats; Rats, Sprague-Dawley; Signal Transduction; Thioglycolates; Thiophenes; Wnt Signaling Pathway	2020
Simultaneous determination of cefixime and erdosteine in combined dosage form using validated spectrophotometric methods. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2020, Nov-05, Volume: 241 Topics: Cefixime; Reproducibility of Results; Spectrophotometry; Thioglycolates; Thiophenes	2020
Erdosteine salvages cardiac necrosis: Novel effect through modulation of MAPK and Nrf-2/HO-1 pathway. Journal of biochemical and molecular toxicology, 2020, Volume: 34, Issue:12 Topics: Animals; Biomarkers; Cardiomyopathies; Cytokines; Dose-Response Relationship, Drug; Heme Oxygenase (Decyclizing); Inflammation Mediators; Isoproterenol; Male; MAP Kinase Signaling System; Necrosis; NF-E2-Related Factor 2; Rats; Signal Transduction; Thioglycolates; Thiophenes	2020
Use of mucolytics in COPD: A Delphi consensus study. Respiratory medicine, 2020, Volume: 175 Topics: Acetylcysteine; Carbocysteine; Consensus; Drug Therapy, Combination; Expectorants; Female; Health Status; Humans; Internationality; Male; Practice Guidelines as Topic; Pulmonary Disease, Chronic Obstructive; Surveys and Questionnaires; Symptom Flare Up; Thioglycolates; Thiophenes; Treatment Outcome	2020
Determination, Isolation, and Identification of Related Impurities in Erdosteine Bulk Drug. Journal of AOAC International, 2022, Apr-27, Volume: 105, Issue:3 Topics: Chromatography, High Pressure Liquid; Drug Contamination; Ethanol; Solvents; Thioglycolates; Thiophenes	2022
The protective effects of erdosteine on subacute diazinon-induced oxidative stress and inflammation in rats. Environmental science and pollution research international, 2022, Volume: 29, Issue:15 Topics: Acetylcholinesterase; Animals; Diazinon; Inflammation; Insecticides; Male; Organophosphorus Compounds; Oxidative Stress; Rats; Rats, Wistar; Thioglycolates; Thiophenes	2022
Tissue-Protective Effect of Erdosteine on Multiple-Organ Injuries Induced by Fine Particulate Matter. Medical science monitor : international medical journal of experimental and clinical research, 2021, Dec-07, Volume: 27 Topics: Animals; Antioxidants; Biomarkers; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Expectorants; Inflammation; Kidney; Lung Injury; Male; Oxidative Stress; Particulate Matter; Rats; Rats, Wistar; Spleen; Thioglycolates; Thiophenes	2021
Erdosteine enhances antibiotic activity against bacteria within biofilm. International journal of antimicrobial agents, 2022, Volume: 59, Issue:3 Topics: Anti-Bacterial Agents; Biofilms; Extracellular Polymeric Substance Matrix; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Thioglycolates; Thiophenes	2022
Erdosteine reduces cytotoxicity induced by alpha- and beta-amanitin, but not gamma-amanitin, in CA3 hepatocyte cultures. Toxicon : official journal of the International Society on Toxinology, 2022, Jul-15, Volume: 213 Topics: Alpha-Amanitin; Amanitins; Hepatocytes; Humans; Thioglycolates; Thiophenes	2022