er-086526 and 3-hydroxybutanal

er-086526 has been researched along with 3-hydroxybutanal* in 1 studies

Other Studies

1 other study(ies) available for er-086526 and 3-hydroxybutanal

Article	Year
Practical stereoselective synthesis of eribulin fragment toward building a hybrid macrocyclic toolbox. Organic letters, 2015, Feb-06, Volume: 17, Issue:3 A practical stereoselective synthesis to obtain the substituted furan ring as the substructure of eribulin is developed. An asymmetric syn-aldol and intramolecular oxy-Michael were two key steps in our approach. The functionalized furan derivatives were then utilized further to build the 14- and 12-membered macrocyclic diversity as trans- and cis-fused (C-29 and C-30) compounds. This is the first report of building a chemical toolbox with macrocyclic small molecules having trans- or cis-fused 14- or 12-membered rings containing the substructure of eribulin and its diastereomer. Topics: Aldehydes; Cyclization; Furans; Ketones; Macrocyclic Compounds; Molecular Structure; Stereoisomerism	2015

Article

Year

Practical stereoselective synthesis of eribulin fragment toward building a hybrid macrocyclic toolbox.

Organic letters, 2015, Feb-06, Volume: 17, Issue:3

A practical stereoselective synthesis to obtain the substituted furan ring as the substructure of eribulin is developed. An asymmetric syn-aldol and intramolecular oxy-Michael were two key steps in our approach. The functionalized furan derivatives were then utilized further to build the 14- and 12-membered macrocyclic diversity as trans- and cis-fused (C-29 and C-30) compounds. This is the first report of building a chemical toolbox with macrocyclic small molecules having trans- or cis-fused 14- or 12-membered rings containing the substructure of eribulin and its diastereomer.

Topics: Aldehydes; Cyclization; Furans; Ketones; Macrocyclic Compounds; Molecular Structure; Stereoisomerism

2015