Compounds > equilenin
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equilenin and 4-hydroxyestrone

equilenin has been researched along with 4-hydroxyestrone in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (25.00)18.2507
2000's2 (50.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Han, X; Liehr, JG1
Blond, SY; Bolton, JL; Chen, Y; Constantinou, AI; Elguindi, EC; Hua, Y; Liu, X; Pisha, E; Shen, L; van Breemen, RB; Zhang, F1
Bolton, JL; Constantinou, AI; Lui, X; Pisha, E1
Bolton, JL; Chandrasena, ER; Peng, KW; Thatcher, GR; van Breemen, RB; Wang, Z; Yuan, Y1

Other Studies

4 other study(ies) available for equilenin and 4-hydroxyestrone

ArticleYear
Microsome-mediated 8-hydroxylation of guanine bases of DNA by steroid estrogens: correlation of DNA damage by free radicals with metabolic activation to quinones.
    Carcinogenesis, 1995, Volume: 16, Issue:10

    Topics: Animals; Biotransformation; Cricetinae; DNA; DNA Damage; Equilenin; Estradiol; Estrogens, Catechol; Estrone; Free Radicals; Guanine; Hydroxyestrones; Hydroxylation; Liver; Male; Mesocricetus; Microsomes, Liver; Quinones

1995
A metabolite of equine estrogens, 4-hydroxyequilenin, induces DNA damage and apoptosis in breast cancer cell lines.
    Chemical research in toxicology, 2000, Volume: 13, Issue:5

    Topics: Apoptosis; Breast Neoplasms; Cell Survival; Comet Assay; DNA Damage; DNA Fragmentation; DNA, Neoplasm; Dose-Response Relationship, Drug; Epithelial Cells; Equilenin; Estradiol Congeners; Estrogens, Catechol; Female; Humans; Hydroxyestrones; Tumor Cells, Cultured

2000
Evidence that a metabolite of equine estrogens, 4-hydroxyequilenin, induces cellular transformation in vitro.
    Chemical research in toxicology, 2001, Volume: 14, Issue:1

    Topics: Animals; Carcinogens; Cell Line; Cell Transformation, Neoplastic; DNA Damage; Epidermal Cells; Epidermis; Equilenin; Estradiol Congeners; Fibroblasts; Horses; Hydroxyestrones; Mice; Mice, Inbred C3H; Reactive Oxygen Species

2001
Redox cycling of catechol estrogens generating apurinic/apyrimidinic sites and 8-oxo-deoxyguanosine via reactive oxygen species differentiates equine and human estrogens.
    Chemical research in toxicology, 2010, Aug-16, Volume: 23, Issue:8

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Cattle; Cell Line, Tumor; Chelating Agents; Copper; Deoxyguanosine; DNA; DNA Damage; DNA, Neoplasm; Equilenin; Estrogens, Catechol; Free Radical Scavengers; Horses; Humans; Hydrogen Peroxide; Hydroxyestrones; Molecular Structure; NADP; Oxidation-Reduction; Reactive Oxygen Species; Structure-Activity Relationship

2010