epz004777 has been researched along with sinefungin* in 1 studies
1 other study(ies) available for epz004777 and sinefungin
Article | Year |
---|---|
Design, synthesis and in vitro anti-Zika virus evaluation of novel Sinefungin derivatives.
We report herein the design and synthesis of a series of novel Sinefungin (SIN) derivatives, based on the structures of SIN and its analogue EPZ004777. Our results reveal that target compounds 1ad-af, 1ba-bb and 1bf-bh show better activity (IC Topics: Adenosine; Animals; Antiviral Agents; Cell Line; Cell Survival; Cricetinae; Dose-Response Relationship, Drug; Drug Design; Microbial Sensitivity Tests; Molecular Structure; Phenylurea Compounds; Structure-Activity Relationship; Zika Virus | 2018 |