epz004777 and sinefungin

epz004777 has been researched along with sinefungin* in 1 studies

Other Studies

1 other study(ies) available for epz004777 and sinefungin

Article	Year
Design, synthesis and in vitro anti-Zika virus evaluation of novel Sinefungin derivatives. European journal of medicinal chemistry, 2018, Sep-05, Volume: 157 We report herein the design and synthesis of a series of novel Sinefungin (SIN) derivatives, based on the structures of SIN and its analogue EPZ004777. Our results reveal that target compounds 1ad-af, 1ba-bb and 1bf-bh show better activity (IC Topics: Adenosine; Animals; Antiviral Agents; Cell Line; Cell Survival; Cricetinae; Dose-Response Relationship, Drug; Drug Design; Microbial Sensitivity Tests; Molecular Structure; Phenylurea Compounds; Structure-Activity Relationship; Zika Virus	2018

Article

Year

Design, synthesis and in vitro anti-Zika virus evaluation of novel Sinefungin derivatives.

European journal of medicinal chemistry, 2018, Sep-05, Volume: 157

We report herein the design and synthesis of a series of novel Sinefungin (SIN) derivatives, based on the structures of SIN and its analogue EPZ004777. Our results reveal that target compounds 1ad-af, 1ba-bb and 1bf-bh show better activity (IC

Topics: Adenosine; Animals; Antiviral Agents; Cell Line; Cell Survival; Cricetinae; Dose-Response Relationship, Drug; Drug Design; Microbial Sensitivity Tests; Molecular Structure; Phenylurea Compounds; Structure-Activity Relationship; Zika Virus

2018