epsilon-viniferin and tetrahydrofuran

A new tetramer oligostilbenoid possessing tetrahydrofuran ring, malaysianol C (1), was isolated from the acetone extract of the stem bark of Dryobalanops lanceolata, together with four known oligostilbenoids nepalensinol E (2), ϵ-viniferin (3), laevifonol (4), and ampelopsin F (5). The structures of isolated compounds were elucidated on the basis of spectral evidence. The antibacterial activity of the isolated compounds was evaluated using resazurin microtitre-plate assay, whereas the cytotoxic activity was tested using MTT assay. The plausible biogenetic routes of the isolated compounds are also discussed.

Topics: Anti-Bacterial Agents; Antineoplastic Agents, Phytogenic; Benzofurans; Dipterocarpaceae; Flavonoids; Furans; Humans; Malaysia; Molecular Structure; Plant Bark; Plant Extracts; Plant Stems; Stereoisomerism; Stilbenes