Page last updated: 2024-08-25

epristeride and finasteride

epristeride has been researched along with finasteride in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's10 (55.56)18.2507
2000's5 (27.78)29.6817
2010's3 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Batchelor, KW; Bramson, HN; Dorsey, GF; Frye, SV; Haffner, CD; Hiner, RN; Maloney, PR; Noe, RA; Stuart, JD; Unwalla, RJ1
Bakshi, RK; Chang, B; Ellsworth, K; Harris, GS; Mosley, RT; Patel, GF; Rasmusson, GH; Tolman, RL1
Baginsky, WF; Bakshi, RK; Bull, H; Chang, B; Cimis, G; Ellsworth, K; Harris, GS; Patel, GF; Rasmusson, GH; Tolman, RL1
Andrews, RC; Cribbs, CM; Dorsey, GF; Frye, SV; Haffner, CD; Hiner, RN; Maloney, PR; Mook, RA; Ray, JA; Wheeler, TN1
Batchelor, KW; Bramson, HN; Dorsey, GF; Frye, SV; Haffner, CD; Hiner, RN; Maloney, PR; Mook, RA; Schweiker, SL; Stuart, JD1
Audia, JE; Hirsch, KS; Jones, CD; Lawhorn, DE; McQuaid, LA; Neubauer, BL; Pennington, PA; Pike, AJ; Stamm, NB; Toomey, RE1
Ballard, S; Blagg, J; Fox, D; Kenny, B1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Biagini, L; Briatico, G; Cominato, C; di Salle, E; Giudici, D; Panzeri, A1
Audia, JE; Bruchovsky, N; Goode, RL; Hsiao, KC; Kaefer, M; Krushinski, JH; Lee, C; Leibovitch, IY; Neubauer, BL; Steidle, CP; Sutkowski, DM1
Berthaut, I; Cussenot, O; Mestayer, C; Mowszowicz, I; Portois, MC1
Diffley, P; Newton, RP; Price, D; Ranjan, M; Stephen, G; Walton, TJ1
Cai, RF; Cui, YG; Di, FS; Jia, Y; Ma, DZ; Tong, JS; Wang, XD; Wang, XH1
Jin, J; Kong, CZ; Li, NC; Na, YQ; Qiu, SP; Song, YS; Sun, G; Sun, YC; Sun, YH; Wang, XF; Wu, SL; Ye, ZQ1
Jiang, S; Liao, C; Nicklaus, MC; Xu, Y; Yao, Z; Zhang, M1
Qiu, Z; Wang, B; Wang, W; Yang, Y; Zhang, P; Zhao, XF1

Reviews

1 review(s) available for epristeride and finasteride

ArticleYear
Pharmacological options in the treatment of benign prostatic hyperplasia.
    Journal of medicinal chemistry, 1997, Apr-25, Volume: 40, Issue:9

    Topics: 5-alpha Reductase Inhibitors; Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Controlled Clinical Trials as Topic; Endothelins; Enzyme Inhibitors; Humans; Male; Prostate; Prostatic Hyperplasia; Receptors, Adrenergic, alpha; Structure-Activity Relationship

1997

Trials

1 trial(s) available for epristeride and finasteride

ArticleYear
[Comparison of different drugs on the treatment of benign prostate hyperplasia].
    Zhonghua wai ke za zhi [Chinese journal of surgery], 2007, Jul-15, Volume: 45, Issue:14

    Topics: 5-alpha Reductase Inhibitors; Adrenergic alpha-Antagonists; Aged; Aged, 80 and over; Androstadienes; Double-Blind Method; Doxazosin; Enzyme Inhibitors; Finasteride; Follow-Up Studies; Humans; Male; Middle Aged; Naphthalenes; Piperazines; Plant Extracts; Prazosin; Prostate; Prostatic Hyperplasia; Quality of Life; Secale; Sulfonamides; Tamsulosin; Treatment Outcome

2007

Other Studies

16 other study(ies) available for epristeride and finasteride

ArticleYear
Structure-activity relationships for inhibition of type 1 and 2 human 5 alpha-reductase and human adrenal 3 beta-hydroxy-delta 5-steroid dehydrogenase/3-keto-delta 5-steroid isomerase by 6-azaandrost-4-en-3-ones: optimization of the C17 substituent.
    Journal of medicinal chemistry, 1995, Jul-07, Volume: 38, Issue:14

    Topics: 3-Hydroxysteroid Dehydrogenases; 5-alpha Reductase Inhibitors; Adrenal Glands; Animals; Azasteroids; Dogs; Humans; Male; Models, Molecular; Rats; Rats, Sprague-Dawley; Steroid Isomerases; Structure-Activity Relationship

1995
4-Aza-3-oxo-5 alpha-androst-1-ene-17 beta-N-aryl-carboxamides as dual inhibitors of human type 1 and type 2 steroid 5 alpha-reductases. Dramatic effect of N-aryl substituents on type 1 and type 2 5 alpha-reductase inhibitory potency.
    Journal of medicinal chemistry, 1995, Aug-18, Volume: 38, Issue:17

    Topics: 5-alpha Reductase Inhibitors; Androstenes; Azasteroids; Humans; Molecular Conformation; Thermodynamics

1995
4,7 beta-Dimethyl-4-azacholestan-3-one (MK-386) and related 4-azasteroids as selective inhibitors of human type 1 5 alpha-reductase.
    Journal of medicinal chemistry, 1994, Nov-11, Volume: 37, Issue:23

    Topics: 5-alpha Reductase Inhibitors; Azasteroids; Humans

1994
6-Azasteroids: structure-activity relationships for inhibition of type 1 and 2 human 5 alpha-reductase and human adrenal 3 beta-hydroxy-delta 5-steroid dehydrogenase/3-keto-delta 5-steroid isomerase.
    Journal of medicinal chemistry, 1994, Jul-22, Volume: 37, Issue:15

    Topics: 3-Hydroxysteroid Dehydrogenases; 5-alpha Reductase Inhibitors; Adrenal Glands; Animals; Azasteroids; Dogs; Humans; Isoenzymes; Rats; Rats, Sprague-Dawley; Steroid Isomerases; Structure-Activity Relationship

1994
6-Azasteroids: potent dual inhibitors of human type 1 and 2 steroid 5 alpha-reductase.
    Journal of medicinal chemistry, 1993, Dec-24, Volume: 36, Issue:26

    Topics: 5-alpha Reductase Inhibitors; Animals; Azasteroids; Baculoviridae; Cell Line; Dihydrotestosterone; Humans; Isoenzymes; Male; Moths; Orchiectomy; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Testosterone; Transfection

1993
Nonsteroidal inhibitors of human type I steroid 5-alpha-reductase.
    Journal of medicinal chemistry, 1993, Feb-05, Volume: 36, Issue:3

    Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; 5-alpha Reductase Inhibitors; Cell Line; Humans; Male; Quinolones; Structure-Activity Relationship

1993
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Effects of 5 alpha-reductase inhibitors on intraprostatic androgens in the rat.
    The Journal of steroid biochemistry and molecular biology, 1995, Volume: 53, Issue:1-6

    Topics: Androstadienes; Androstenes; Animals; Azasteroids; Cholestenone 5 alpha-Reductase; Dihydrotestosterone; Finasteride; Humans; In Vitro Techniques; Male; Oxidoreductases; Prostate; Rats; Testosterone

1995
Characterization of type I 5 alpha-reductase activity in DU145 human prostatic adenocarcinoma cells.
    The Journal of steroid biochemistry and molecular biology, 1996, Volume: 58, Issue:2

    Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; 5-alpha Reductase Inhibitors; Adenocarcinoma; Androstadienes; Benzoquinones; Cell Division; Enzyme Inhibitors; Finasteride; Gene Expression Regulation, Neoplastic; Humans; Isoenzymes; Male; Prostatic Neoplasms; RNA, Messenger; Selection, Genetic; Skin; Testosterone; Tumor Cells, Cultured

1996
Pharmacological and molecular evidence for the expression of the two steroid 5 alpha-reductase isozymes in normal and hyperplastic human prostatic cells in culture.
    The Prostate, 1997, Aug-01, Volume: 32, Issue:3

    Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; 5-alpha Reductase Inhibitors; Androstadienes; Base Sequence; Benzoquinones; Blotting, Northern; Cell Line; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epithelial Cells; Epithelium; Fibroblasts; Finasteride; Gene Expression Regulation, Enzymologic; Humans; Isoenzymes; Male; Oligonucleotides; Polymerase Chain Reaction; Prostate; Prostatic Hyperplasia; RNA, Messenger

1997
Comparative study of human steroid 5alpha-reductase isoforms in prostate and female breast skin tissues: sensitivity to inhibition by finasteride and epristeride.
    Life sciences, 2002, May-31, Volume: 71, Issue:2

    Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; 5-alpha Reductase Inhibitors; Androstadienes; Breast; Enzyme Inhibitors; Female; Finasteride; Humans; In Vitro Techniques; Isoenzymes; Male; Middle Aged; Prostate

2002
[Effect of large-dosage of 5alpha-reductase inhibitors on the spermatogenesis of male rats].
    Zhonghua nan ke xue = National journal of andrology, 2005, Volume: 11, Issue:9

    Topics: 5-alpha Reductase Inhibitors; Androstadienes; Animals; Dose-Response Relationship, Drug; Finasteride; Male; Rats; Rats, Sprague-Dawley; Spermatogenesis

2005
Discovery of a novel hybrid from finasteride and epristeride as 5α-reductase inhibitor.
    Bioorganic & medicinal chemistry letters, 2011, Jan-01, Volume: 21, Issue:1

    Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; 5-alpha Reductase Inhibitors; Androstadienes; Binding Sites; Catalytic Domain; Computer Simulation; Drug Evaluation, Preclinical; Finasteride; Humans

2011
Effects of competitive and noncompetitive 5α-reductase inhibitors on serum and intra-prostatic androgens in beagle dogs.
    Chinese medical journal, 2013, Volume: 126, Issue:4

    Topics: 5-alpha Reductase Inhibitors; Androgens; Androstadienes; Animals; Dihydrotestosterone; Dogs; Finasteride; Male; Prostate

2013