Page last updated: 2024-08-25

epiroprim and trimetrexate

epiroprim has been researched along with trimetrexate in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (80.00)18.2507
2000's1 (20.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Queener, SF1
Gangjee, A; Kisliuk, RL; Queener, SF; Vasudevan, A1
Griffin, RJ; Grunwaldt, JD; Lambert, PA; Meek, MA; Queener, SF; Robson, C; Schmidt, D1
Cody, V; Galitsky, N; Gangjee, A; Guo, X; Luft, JR; Pangborn, W; Queener, SF1
Chan, DC; Fu, H; Queener, SF; Rosowsky, A1

Reviews

1 review(s) available for epiroprim and trimetrexate

ArticleYear
New drug developments for opportunistic infections in immunosuppressed patients: Pneumocystis carinii.
    Journal of medicinal chemistry, 1995, Nov-24, Volume: 38, Issue:24

    Topics: Animals; Drug Design; Humans; Immunosuppression Therapy; Molecular Structure; Opportunistic Infections; Pneumonia, Pneumocystis; Structure-Activity Relationship

1995

Other Studies

4 other study(ies) available for epiroprim and trimetrexate

ArticleYear
2,4-diamino-5-deaza-6-substituted pyrido[2,3-d]pyrimidine antifolates as potent and selective nonclassical inhibitors of dihydrofolate reductases.
    Journal of medicinal chemistry, 1996, Mar-29, Volume: 39, Issue:7

    Topics: Animals; Antineoplastic Agents; Cell Division; Drug Screening Assays, Antitumor; Folic Acid Antagonists; Humans; Liver; Mice; Molecular Structure; Neoplasms, Experimental; Pneumocystis; Pyrimidines; Rats; Recombinant Proteins; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase; Toxoplasma

1996
Nonclassical 2,4-diamino-5-aryl-6-ethylpyrimidine antifolates: activity as inhibitors of dihydrofolate reductase from Pneumocystis carinii and Toxoplasma gondii and as antitumor agents.
    Journal of medicinal chemistry, 1997, Sep-12, Volume: 40, Issue:19

    Topics: Animals; Antineoplastic Agents; Cell Survival; Folic Acid Antagonists; Indicators and Reagents; Kinetics; Liver; Lymphoma, Large B-Cell, Diffuse; Mice; Pneumocystis; Pyrimidines; Rats; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase; Toxoplasma

1997
Selective Pneumocystis carinii dihydrofolate reductase inhibitors: design, synthesis, and biological evaluation of new 2,4-diamino-5-substituted-furo[2,3-d]pyrimidines.
    Journal of medicinal chemistry, 1998, Apr-09, Volume: 41, Issue:8

    Topics: Animals; Binding Sites; Crystallography, X-Ray; Drug Design; Folic Acid Antagonists; Liver; Models, Molecular; NAD; Naphthalenes; Phenylalanine; Pneumocystis; Pyrimidines; Rats; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase; Toxoplasma

1998
Synthesis of 2,4-diamino-6-[2'-O-(omega-carboxyalkyl)oxydibenz[b,f]azepin-5-yl]methylpteridines as potent and selective inhibitors of Pneumocystis carinii, Toxoplasma gondii, and Mycobacterium avium dihydrofolate reductase.
    Journal of medicinal chemistry, 2004, May-06, Volume: 47, Issue:10

    Topics: Animals; Azepines; Benzazepines; Folic Acid Antagonists; Models, Molecular; Mycobacterium avium; Pneumocystis carinii; Pteridines; Rats; Solubility; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase; Toxoplasma; Water

2004