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epipodophyllotoxin and podophyllotoxin

epipodophyllotoxin has been researched along with podophyllotoxin in 6 studies

*Podophyllotoxin: A lignan (LIGNANS) found in PODOPHYLLIN resin from the roots of PODOPHYLLUM plants. It is a potent spindle poison, toxic if taken internally, and has been used as a cathartic. It is very irritating to skin and mucous membranes, has keratolytic actions, has been used to treat warts and keratoses, and may have antineoplastic properties, as do some of its congeners and derivatives. [MeSH]

*Podophyllotoxin: A lignan (LIGNANS) found in PODOPHYLLIN resin from the roots of PODOPHYLLUM plants. It is a potent spindle poison, toxic if taken internally, and has been used as a cathartic. It is very irritating to skin and mucous membranes, has keratolytic actions, has been used to treat warts and keratoses, and may have antineoplastic properties, as do some of its congeners and derivatives. [MeSH]

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19901 (16.67)18.7374
1990's3 (50.00)18.2507
2000's1 (16.67)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Brewer, CF; Gensler, WJ; Horwitz, SB; Loike, JD; Sternlicht, H1
Castro, MA; Gordaliza, M; Lopez, JL; Miguel del Corral, JM; Morales, LJ; San Feliciano, A1
Castro, MA; Faircloth, GT; Gordaliza, M; López-Vázquez, ML; Miguel del Corral, JM; San Feliciano, A1
Charlton, JL1
Abad, A; de Pascual-Teresa, B; del Olmo, E; López-Pérez, JL; San Feliciano, A1
Abad, A; Andreu, JM; Barasoain, I; del Olmo, E; Díaz, JF; Francesch, A; García-Fernández, LF; López-Pérez, JL; San Feliciano, A; Trigili, C1

Reviews

1 review(s) available for epipodophyllotoxin and podophyllotoxin

ArticleYear
Antiviral activity of lignans.
    Journal of natural products, 1998, Volume: 61, Issue:11

    Topics: Animals; Antiviral Agents; Humans; Lignans; Plants, Medicinal; Viruses

1998

Other Studies

5 other study(ies) available for epipodophyllotoxin and podophyllotoxin

ArticleYear
Conformational analysis of podophyllotoxin and its congeners. Structure--activity relationship in microtubule assembly.
    Journal of medicinal chemistry, 1979, Volume: 22, Issue:3

    Topics: Animals; Brain; In Vitro Techniques; Magnetic Resonance Spectroscopy; Microtubules; Molecular Conformation; Podophyllotoxin; Structure-Activity Relationship

1979
Methyl ethers of podophyllotoxin-related cyclolignans.
    Journal of natural products, 1995, Volume: 58, Issue:6

    Topics: Animals; Antineoplastic Agents, Phytogenic; Drug Screening Assays, Antitumor; Humans; Magnetic Resonance Spectroscopy; Mice; Podophyllotoxin; Stereoisomerism; Tumor Cells, Cultured

1995
Immunosuppressive cyclolignans.
    Journal of medicinal chemistry, 1996, Jul-05, Volume: 39, Issue:14

    Topics: Animals; Cells, Cultured; Immunosuppressive Agents; Lignans; Lymphocyte Culture Test, Mixed; Mice; Mice, Inbred BALB C; Molecular Structure; Spleen; Structure-Activity Relationship; T-Lymphocytes

1996
Synthesis and cytotoxicity of hydrophobic esters of podophyllotoxins.
    Bioorganic & medicinal chemistry letters, 2004, Mar-08, Volume: 14, Issue:5

    Topics: Animals; Cell Line, Tumor; Esters; Humans; Hydrophobic and Hydrophilic Interactions; Mice; Mice, Inbred DBA; Podophyllotoxin

2004
Synthesis and antimitotic and tubulin interaction profiles of novel pinacol derivatives of podophyllotoxins.
    Journal of medicinal chemistry, 2012, Aug-09, Volume: 55, Issue:15

    Topics: Antimitotic Agents; Antineoplastic Agents; Binding, Competitive; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Humans; Microtubules; Models, Molecular; Podophyllotoxin; Stereoisomerism; Tubulin Modulators

2012