epinastine has been researched along with terfenadine in 17 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (5.88) | 18.7374 |
| 1990's | 7 (41.18) | 18.2507 |
| 2000's | 8 (47.06) | 29.6817 |
| 2010's | 1 (5.88) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Keserü, GM | 1 |
| Caron, G; Ermondi, G | 1 |
| Nagashima, R; Nishikawa, T; Tobita, M | 1 |
| Jia, L; Sun, H | 1 |
| Adamus, WS; Kuthan, H; Schilling, JC | 1 |
| Bechtel, WD; Fügner, A; Kuhn, FJ; Mierau, J | 1 |
| Iga, T; Kotaki, H; Ohtani, H; Sawada, Y | 1 |
| Funae, Y; Hiroi, T; Igarashi, T; Kishimoto, W; Sakai, K | 1 |
| Chachin, M; Horio, Y; Katayama, Y; Kitagawa, H; Kurachi, Y; Ohmura, T; Uchida, S; Yamada, M | 1 |
| Danielson, L; DeVos, C; Grant, JA; Rihoux, JP | 1 |
| Chachin, M; Igarashi, T; Ikeda, H; Ikegami, K; Kitagawa, H; Nagakura, A; Ohmura, T; Tarui, S; Uchida, S | 1 |
| Hanada, E; Hirota, M; Iga, T; Kotaki, H; Nakaya, H; Ohtani, H; Sato, H; Sawada, Y; Uemura, H | 1 |
| Izu, K; Tokura, Y | 1 |
| Ago, J; Ishikawa, T; Kamei, C; Matsumoto, N; Murakami, A; Rahman, A; Takechi, K | 1 |
| Fukui, H; Izumi, N; Mizuguchi, H; Ogino, S; Umehara, H | 1 |
| dos Santos, RV; Lima, HC; Magerl, M; Mlynek, A | 1 |
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
3 trial(s) available for epinastine and terfenadine
| Article | Year |
|---|---|
Antihistaminic activity and side effect profile of epinastine and terfenadine in healthy volunteers.
Topics: Administration, Oral; Adult; Affect; Benzhydryl Compounds; Dibenzazepines; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Histamine; Histamine H1 Antagonists; Humans; Imidazoles; Male; Middle Aged; Psychometrics; Reaction Time; Terfenadine | 1990 |
A double-blind, single-dose, crossover comparison of cetirizine, ebastine, epinastine, fexofenadine, terfenadine, and loratadine versus placebo: suppression of histamine-induced wheal and flare response for 24 h in healthy male subjects.
Topics: Adult; Butyrophenones; Cetirizine; Cross-Over Studies; Dibenzazepines; Double-Blind Method; Histamine; Histamine H1 Antagonists; Histamine Release; Humans; Hypersensitivity, Immediate; Imidazoles; Loratadine; Male; Piperidines; Skin Tests; Terfenadine; Urticaria | 1999 |
Suppression of histamine- and allergen-induced skin reactions: comparison of first- and second-generation antihistamines.
Topics: Adult; Allergens; Animals; Dermatophagoides pteronyssinus; Dibenzazepines; Double-Blind Method; Female; Histamine; Histamine H1 Antagonists; Histamine H1 Antagonists, Non-Sedating; Humans; Hydroxyzine; Imidazoles; Loratadine; Male; Middle Aged; Rhinitis, Allergic, Perennial; Skin Tests; Terfenadine; Treatment Outcome; Urticaria | 2009 |
14 other study(ies) available for epinastine and terfenadine
| Article | Year |
|---|---|
Prediction of hERG potassium channel affinity by traditional and hologram qSAR methods.
Topics: Cation Transport Proteins; Databases, Factual; Discriminant Analysis; Ether-A-Go-Go Potassium Channels; Holography; Linear Models; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship | 2003 |
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water | 2005 |
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors.
Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated | 2005 |
Support vector machines classification of hERG liabilities based on atom types.
Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Chemical; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Predictive Value of Tests; ROC Curve | 2008 |
In vitro and in vivo studies of the non-sedating antihistamine epinastine.
Topics: Animals; Astemizole; Benzhydryl Compounds; Benzimidazoles; Cats; Dibenzazepines; Dogs; Female; Guinea Pigs; Histamine H1 Antagonists; Histamine Release; Ileum; Imidazoles; In Vitro Techniques; Ketotifen; Male; Promethazine; Rats; Rats, Inbred Strains; Receptors, Histamine H1; Sleep; Terfenadine; Wakefulness | 1988 |
A comparative pharmacokinetic-pharmacodynamic study of the electrocardiographic effects of epinastine and terfenadine in rats.
Topics: Animals; Bradycardia; Chromatography, High Pressure Liquid; Dibenzazepines; Dose-Response Relationship, Drug; Electrocardiography; Half-Life; Heart; Heart Rate; Histamine H1 Antagonists; Imidazoles; Infusions, Intravenous; Male; Rats; Rats, Sprague-Dawley; Terfenadine | 1997 |
Metabolism of epinastine, a histamine H1 receptor antagonist, in human liver microsomes in comparison with that of terfenadine.
Topics: Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2B6; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dibenzazepines; Histamine H1 Antagonists; Humans; Imidazoles; In Vitro Techniques; Intestine, Small; Isoenzymes; Microsomes, Liver; Mixed Function Oxygenases; Oxidoreductases, N-Demethylating; Recombinant Proteins; Terfenadine | 1997 |
Epinastine, a nonsedating histamine H1 receptor antagonist, has a negligible effect on HERG channel.
Topics: Animals; Astemizole; Cation Transport Proteins; Dibenzazepines; DNA-Binding Proteins; Dose-Response Relationship, Drug; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Gene Expression; Histamine H1 Antagonists; Humans; Imidazoles; Membrane Potentials; Oocytes; Potassium Channels; Potassium Channels, Voltage-Gated; Terfenadine; Trans-Activators; Transcriptional Regulator ERG; Xenopus | 1999 |
Effects of terfenadine, astemizole and epinastine on electrocardiogram in conscious cynomolgus monkeys.
Topics: Animals; Arrhythmias, Cardiac; Astemizole; Dibenzazepines; Electrocardiography; Heart Block; Histamine H1 Antagonists; Imidazoles; Macaca fascicularis; Male; Terfenadine; Time Factors | 1999 |
Inhibitory effects of the antihistamines epinastine, terfenadine, and ebastine on potassium currents in rat ventricular myocytes.
Topics: Animals; Butyrophenones; Dibenzazepines; Electrophysiology; Heart Ventricles; Histamine H1 Antagonists; Imidazoles; Male; Patch-Clamp Techniques; Piperidines; Potassium Channels; Rats; Rats, Sprague-Dawley; Terfenadine | 1999 |
The various effects of four H1-antagonists on serum substance P levels in patients with atopic dermatitis.
Topics: Adult; Anti-Allergic Agents; Cetirizine; Dermatitis, Atopic; Dibenzazepines; Dibenzoxepins; E-Selectin; Female; Histamine H1 Antagonists; Humans; Imidazoles; Intercellular Adhesion Molecule-1; Male; Olopatadine Hydrochloride; Substance P; Terfenadine; Vascular Cell Adhesion Molecule-1 | 2005 |
Influences of histamine H1 receptor antagonists on maximal electroshock seizure in infant rats.
Topics: Administration, Oral; Animals; Animals, Suckling; Chlorpheniramine; Cyproheptadine; Dibenzazepines; Diphenhydramine; Dose-Response Relationship, Drug; Electroencephalography; Electroshock; Histamine H1 Antagonists; Imidazoles; Ketotifen; Male; Rats; Rats, Wistar; Seizures; Terfenadine; Time Factors | 2007 |
Analysis of disease-dependent sedative profiles of H(1)-antihistamines by large-scale surveillance using the visual analog scale.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Asthma; Butyrophenones; Cetirizine; Child; Chlorpheniramine; Dermatitis, Atopic; Dibenzazepines; Dibenzoxepins; Female; Histamine H1 Antagonists; Histamine H1 Antagonists, Non-Sedating; Humans; Imidazoles; Japan; Male; Middle Aged; Olopatadine Hydrochloride; Pain Measurement; Piperidines; Population Surveillance; Psychomotor Performance; Pyridines; Quality of Life; Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal; Sleep Stages; Surveys and Questionnaires; Terfenadine; Urticaria | 2008 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |