epinastine has been researched along with histamine in 18 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (5.56) | 18.7374 |
| 1990's | 5 (27.78) | 18.2507 |
| 2000's | 8 (44.44) | 29.6817 |
| 2010's | 4 (22.22) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Izushi, K; Kamei, C; Tasaka, K; Tsujimoto, S; Yoshida, T | 1 |
| Kanai, Y; Misawa, M | 1 |
| Adamus, WS; Kuthan, H; Schilling, JC | 1 |
| Adamus, WS; Lohmann, H; Oldigs-Kerber, J | 1 |
| Aritake, K; Hayashi, K; Hayashi, M; Hirotsu, I; Hizue, M; Kimura, Y; Matsushita, N; Mitsui, K; Nakajima, H; Takada, A; Tani, T | 1 |
| Danielson, L; DeVos, C; Grant, JA; Rihoux, JP | 1 |
| Igeta, K; Inagaki, N; Kawasaki, H; Musoh, K; Nagai, H; Nagao, M; Nakamura, N | 1 |
| Furue, M; Koga, T; Terao, H | 1 |
| Hashimoto, K; Murakami, S; Yahata, Y | 1 |
| Hirano, S; Kamei, J; Miyata, S; Onodera, K | 1 |
| Alejandra Hossen, M; Fujii, Y; Kamei, C; Kishi, Y; Tsumuro, T | 1 |
| Beauregard, C; Gamache, D; Roberts, L; Stephens, D; Yanni, J | 1 |
| dos Santos, RV; Lima, HC; Magerl, M; Mlynek, A | 1 |
| Bonini, S; Lambiase, A; Micera, A | 1 |
| Inoue, T; Sugimoto, Y; Suzuki, Y; Yamamoto, A | 1 |
| Ishida, S; Iwata, D; Nakazono, Y; Namba, K; Tagawa, Y | 1 |
| Arai, R; Fukushima, A; Hino, S; Ishida, W; Kishimoto, T; Matsunaga, T; Minami, T; Nakajima, I; Yamagami, S | 1 |
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
1 review(s) available for epinastine and histamine
| Article | Year |
|---|---|
Multiple action agents and the eye: do they really stabilize mast cells?
Topics: Animals; Anti-Inflammatory Agents; Arachidonic Acid; Conjunctivitis, Allergic; Cytokines; Dibenzazepines; Dibenzoxepins; Histamine; Histamine Antagonists; Humans; Imidazoles; Immunity, Innate; Ketotifen; Mast Cells; Olopatadine Hydrochloride; Phthalazines | 2009 |
6 trial(s) available for epinastine and histamine
| Article | Year |
|---|---|
Antihistaminic activity and side effect profile of epinastine and terfenadine in healthy volunteers.
Topics: Administration, Oral; Adult; Affect; Benzhydryl Compounds; Dibenzazepines; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Histamine; Histamine H1 Antagonists; Humans; Imidazoles; Male; Middle Aged; Psychometrics; Reaction Time; Terfenadine | 1990 |
Pharmacodynamics of the new H1-antagonist 3-amino-9,13b-dihydro-1H-dibenz[c,f]imidazo[1,5-a]azepine hydrochloride in volunteers.
Topics: Adult; Azepines; Dibenzazepines; Double-Blind Method; Emotions; Flicker Fusion; Histamine; Histamine H1 Antagonists; Humans; Imidazoles; Ketotifen; Male; Psychomotor Performance; Reaction Time; Skin Tests | 1987 |
A double-blind, single-dose, crossover comparison of cetirizine, ebastine, epinastine, fexofenadine, terfenadine, and loratadine versus placebo: suppression of histamine-induced wheal and flare response for 24 h in healthy male subjects.
Topics: Adult; Butyrophenones; Cetirizine; Cross-Over Studies; Dibenzazepines; Double-Blind Method; Histamine; Histamine H1 Antagonists; Histamine Release; Humans; Hypersensitivity, Immediate; Imidazoles; Loratadine; Male; Piperidines; Skin Tests; Terfenadine; Urticaria | 1999 |
Effects of cetirizine and epinastine on the skin response to histamine iontophoresis.
Topics: Administration, Oral; Adult; Cetirizine; Cross-Over Studies; Dermatitis, Atopic; Dibenzazepines; Double-Blind Method; Drug Administration Schedule; Female; Histamine; Histamine H1 Antagonists; Humans; Imidazoles; Iontophoresis; Male; Skin | 2001 |
Suppression of histamine- and allergen-induced skin reactions: comparison of first- and second-generation antihistamines.
Topics: Adult; Allergens; Animals; Dermatophagoides pteronyssinus; Dibenzazepines; Double-Blind Method; Female; Histamine; Histamine H1 Antagonists; Histamine H1 Antagonists, Non-Sedating; Humans; Hydroxyzine; Imidazoles; Loratadine; Male; Middle Aged; Rhinitis, Allergic, Perennial; Skin Tests; Terfenadine; Treatment Outcome; Urticaria | 2009 |
Evaluating the efficacy of epinastine ophthalmic solution using a conjunctivitis allergen challenge model in patients with birch pollen allergic conjunctivitis.
Topics: Adult; Allergens; Anti-Allergic Agents; Betula; Biomarkers; Conjunctivitis, Allergic; Dibenzazepines; Female; Histamine; Humans; Imidazoles; Male; Middle Aged; Ophthalmic Solutions; Phenotype; Pollen; Tears; Treatment Outcome | 2017 |
11 other study(ies) available for epinastine and histamine
| Article | Year |
|---|---|
Comparison of pharmacological properties of optical isomers and a racemic mixture of epinastine.
Topics: Animals; Dibenzazepines; Electroencephalography; Guinea Pigs; Histamine; Histamine H1 Antagonists; Histamine Release; Imidazoles; Male; Mast Cells; Mice; Mice, Inbred Strains; Motor Activity; Muscle Contraction; p-Methoxy-N-methylphenethylamine; Rats; Rats, Inbred Strains; Sleep; Stereoisomerism | 1991 |
Effect of the new antiallergic drug epinastine on chemical mediator induced bronchoconstrictions in guinea pigs.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Bradykinin; Bronchoconstriction; Dibenzazepines; Guinea Pigs; Histamine; Histamine H1 Antagonists; Imidazoles; Ketotifen; Male; Neurokinin A; Phthalazines; Piperazines; Prostaglandin D2; Prostaglandin Endoperoxides, Synthetic; SRS-A; Substance P | 1991 |
Pharmacological studies on the novel antiallergic drug HQL-79: II. Elucidation of mechanisms for antiallergic and antiasthmatic effects.
Topics: Animals; Anti-Allergic Agents; Anti-Asthmatic Agents; Antigens; Capillary Permeability; Dibenzazepines; Dinoprostone; Dose-Response Relationship, Drug; Free Radical Scavengers; Guinea Pigs; Histamine; Histamine H1 Antagonists; Histamine Release; Ileum; Imidazoles; In Vitro Techniques; Intramolecular Oxidoreductases; Ketotifen; Leukotriene B4; Leukotriene C4; Lipocalins; Lung; Male; Mice; Mice, Inbred ICR; Muscle Contraction; Piperidines; Prostaglandin D2; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Respiratory Hypersensitivity; Serotonin; Sheep; Skin Physiological Phenomena; Trachea | 1998 |
Evaluation of anti-scratch properties of oxatomide and epinastine in mice.
Topics: Animals; Anti-Allergic Agents; Antipruritics; Capillary Permeability; Dibenzazepines; Dinitrofluorobenzene; Edema; Female; Histamine; Histamine H1 Antagonists; Imidazoles; Mice; Mice, Inbred BALB C; Mice, Inbred ICR; Passive Cutaneous Anaphylaxis; Piperazines; Substance P | 2000 |
A new histamine measurement system employing a confocal laser microscope and cultured human dermal microvascular endothelial cells.
Topics: Anti-Allergic Agents; Calcium; Cells, Cultured; Dibenzazepines; Endothelium, Vascular; Histamine; Histamine H1 Antagonists; Humans; Imidazoles; Intracellular Membranes; Microcirculation; Microscopy, Confocal; Osmolar Concentration; Skin | 2003 |
Effects of histamine H(1) receptor antagonists on depressive-like behavior in diabetic mice.
Topics: Animals; Cetirizine; Depression; Dibenzazepines; Dose-Response Relationship, Drug; Histamine; Histamine H1 Antagonists; Hypothalamus; Imidazoles; Male; Mice; Mice, Inbred ICR; Motor Activity | 2006 |
Nasal congestion model in Brown Norway rats and the effects of some H1-antagonists.
Topics: Animals; Chlorpheniramine; Dibenzazepines; Disease Models, Animal; Histamine; Histamine H1 Antagonists; Imidazoles; Ketotifen; Male; Nasal Mucosa; Plethysmography, Whole Body; Rats; Rats, Inbred BN; Rhinitis; Toluene 2,4-Diisocyanate | 2006 |
Duration of action of topical antiallergy drugs in a Guinea pig model of histamine-induced conjunctival vascular permeability.
Topics: Administration, Topical; Animals; Anti-Allergic Agents; Capillary Permeability; Conjunctiva; Delayed-Action Preparations; Dibenzazepines; Dibenzoxepins; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Histamine H1 Antagonists; Imidazoles; Ketotifen; Male; Olopatadine Hydrochloride; Ophthalmic Solutions; Phthalazines | 2007 |
Prophylactic effects of the histamine H1 receptor antagonist epinastine and the dual thromboxane A2 receptor and chemoattractant receptor-homologous molecule expressed on Th2 cells antagonist ramatroban on allergic rhinitis model in mice.
Topics: Animals; Anti-Allergic Agents; Behavior, Animal; Benzoquinones; Carbazoles; Dibenzazepines; Disease Models, Animal; Eosinophils; Female; Heptanoic Acids; Histamine; Histamine H1 Antagonists; Imidazoles; Mice; Mice, Inbred BALB C; Nasal Mucosa; Prostaglandin Antagonists; Receptors, Immunologic; Receptors, Prostaglandin; Receptors, Thromboxane A2, Prostaglandin H2; Rhinitis, Allergic, Seasonal; Severity of Illness Index; Sneezing; Sulfonamides; Th2 Cells | 2011 |
In vitro and in vivo performance of epinastine hydrochloride-releasing contact lenses.
Topics: Animals; Conjunctivitis, Allergic; Contact Lenses, Hydrophilic; Delayed-Action Preparations; Dibenzazepines; Disease Models, Animal; Drug Delivery Systems; Guinea Pigs; Histamine; Histamine H1 Antagonists; Imidazoles; In Vitro Techniques; Male; Ophthalmic Solutions; Osmolar Concentration | 2019 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |