Page last updated: 2024-08-24

epigallocatechin gallate and luteolin

epigallocatechin gallate has been researched along with luteolin in 35 studies

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (5.71)29.6817
2010's27 (77.14)24.3611
2020's6 (17.14)2.80

Authors

AuthorsStudies
Backlund, A; Bohlin, L; Gottfries, J; Larsson, J1
Brun, R; Lack, G; Perozzo, R; Rüedi, P; Scapozza, L; Tasdemir, D1
Amić, D; Lucić, B1
Fujiwara, K; Murakami, N; Tamura, S; Yoshihira, K1
Abramson, HN1
Cai, S; Chu, L; Gao, F; Ji, B; Jia, G; Liu, J; Liu, Y; Wang, A; Wei, Y; Wu, W; Xie, L; Zhang, D; Zhou, F1
Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P1
Caine, J; Cavanagh, K; Churches, QI; Duggan, PJ; Epa, VC; Meyer, AG; Streltsov, V; Tranberg, CE; Varghese, JN; Waddington, L1
Bicknell, KA; Farrimond, JA; Putnam, SE; Swioklo, S; Watson, KA; Williamson, EM1
Cahlikova, L; Chlebek, J; Havrankova, J; Hofman, J; Hostalkova, A; Lundova, T; Musilek, K; Novotna, E; Wsol, V; Zemanova, L1
Chen, L; Jiao, R; Li, X; Liao, W; Ma, X; Wang, Y1
Aquino, TM; Araújo-Júnior, JX; da Silva-Júnior, EF; Leoncini, GO; Rodrigues, ÉES1
Bai, M; Huang, XX; Ren, Q; Song, SJ; Wang, W; Wang, XB; Wang, YX; Yan, ZY; Zhao, L1
Guo, CL; Guo, SJ; Jiang, B; Li, N; Li, XQ; Shi, DY; Wang, LJ1
Golonko, A; Lazny, R; Lewandowski, W; Pienkowski, T; Roszko, M; Swislocka, R1
Jin, YS1
Kalra, S; Khatik, GL; Kumar, GN; Kumar, R; Narang, R; Nayak, SK; Singh, SK; Sudhakar, K1
Bernatchez, JA; Li, J; Li, R; Luan, Y; Siqueira-Neto, JL; Tran, LT1
Albiñana, CB; Brynda, J; Fanfrlík, J; Flieger, M; Hodek, J; Karlukova, E; Konvalinka, J; Kožíšek, M; Machara, A; Majer, P; Radilová, K; Weber, J; Zima, V1
Fong, J; Korobkova, EA; Maran, U; Oja, M; Rice, M; Samuels, K; Sapse, AM; Williams, AK; Wong, B1
Amin, AR; Brandes, JC; Chen, ZG; Khuri, FR; Peng, S; Shin, DM; Shin, HJ; Tighiouart, M; Wang, D; Zhang, H1
Iwasaki, T; Miyai, S; Ohtsuki, K; Shamsa, F; Yamaguchi, A1
Ali, ZY; El-Hawary, SA; Sokkar, NM; Yehia, MM1
Guo, X; Huang, F; Liu, B; Liu, K; Shao, L; Wang, M1
Ahmad, A; Faisal, M; Farhan, M; Hadi, SM; Khan, HY; Sarkar, FH; Ullah, MF; Zubair, H1
Bringmann, A; Chen, R; Grosche, A; Hollborn, M; Kohen, L; Reichenbach, A; Wiedemann, P1
Cho, JH; Cho, KK; Kang, SN; Kim, IS; Lee, JS; Lee, OH; Park, JH1
Liu, B; Liu, K; Mei, F; Pan, G; Sun, Y; Xiao, N1
Bigelow, RL; Cardelli, JA; Coleman, DT; Gray, AL; Stephens, CA1
Huang, F; Kou, J; Li, Y; Liu, B; Liu, K; Wu, J; Xu, X1
Gutierrez-Merino, C; Lagoa, R; Samhan-Arias, AK1
Yi, YS1
Luca, A; Paduraru, L; Stanciu, GD; Stefanescu, R; Tamba, BI1
Gordon, M; Kehinde, I; Khan, R; Nlooto, M1
Hanci, H; Igan, H1

Reviews

8 review(s) available for epigallocatechin gallate and luteolin

ArticleYear
The medicinal chemistry of Chikungunya virus.
    Bioorganic & medicinal chemistry, 2017, 08-15, Volume: 25, Issue:16

    Topics: Animals; Antiviral Agents; Biological Products; Chemistry, Pharmaceutical; Chikungunya Fever; Chikungunya virus; Dose-Response Relationship, Drug; Humans; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship

2017
Recent progress of the development of dipeptidyl peptidase-4 inhibitors for the treatment of type 2 diabetes mellitus.
    European journal of medicinal chemistry, 2018, May-10, Volume: 151

    Topics: Animals; Blood Glucose; Diabetes Mellitus, Type 2; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Humans; Hypoglycemic Agents; Molecular Docking Simulation; Structure-Activity Relationship

2018
Another look at phenolic compounds in cancer therapy the effect of polyphenols on ubiquitin-proteasome system.
    European journal of medicinal chemistry, 2019, Apr-01, Volume: 167

    Topics: Animals; Diet; Humans; Neoplasms; Phenols; Polyphenols; Proteasome Endopeptidase Complex; Ubiquitin

2019
Recent advances in natural antifungal flavonoids and their derivatives.
    Bioorganic & medicinal chemistry letters, 2019, 10-01, Volume: 29, Issue:19

    Topics: Antifungal Agents; Biological Products; Flavonoids; Fungi; Humans; Mycoses

2019
Recent advancements in mechanistic studies and structure activity relationship of F
    European journal of medicinal chemistry, 2019, Nov-15, Volume: 182

    Topics: Animals; Anti-Bacterial Agents; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium; Proton-Translocating ATPases; Structure-Activity Relationship

2019
Drugs for the Treatment of Zika Virus Infection.
    Journal of medicinal chemistry, 2020, 01-23, Volume: 63, Issue:2

    Topics: Animals; Antiviral Agents; Drug Development; Drug Discovery; Humans; Viral Vaccines; Zika Virus; Zika Virus Infection

2020
Regulatory Roles of Flavonoids on Inflammasome Activation during Inflammatory Responses.
    Molecular nutrition & food research, 2018, Volume: 62, Issue:13

    Topics: Animals; Apigenin; Biflavonoids; Catechin; Chalcones; Drug Development; Flavonoids; Humans; Inflammasomes; Inflammation; Luteolin; Proanthocyanidins; Quercetin; Rutin

2018
Secondary Metabolites from Plants Possessing Inhibitory Properties against Beta-Amyloid Aggregation as Revealed by Thioflavin-T Assay and Correlations with Investigations on Transgenic Mouse Models of Alzheimer's Disease.
    Biomolecules, 2020, 06-06, Volume: 10, Issue:6

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Benzothiazoles; Biological Products; Catechin; Flavonoids; Fluorescent Dyes; Luteolin; Mice; Mice, Transgenic; Protein Aggregates; Silybin

2020

Other Studies

27 other study(ies) available for epigallocatechin gallate and luteolin

ArticleYear
Expanding the ChemGPS chemical space with natural products.
    Journal of natural products, 2005, Volume: 68, Issue:7

    Topics: Biological Products; Combinatorial Chemistry Techniques; Computer Graphics; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Drug Evaluation, Preclinical; Molecular Structure; Prostaglandin-Endoperoxide Synthases; Structure-Activity Relationship

2005
Inhibition of Plasmodium falciparum fatty acid biosynthesis: evaluation of FabG, FabZ, and FabI as drug targets for flavonoids.
    Journal of medicinal chemistry, 2006, Jun-01, Volume: 49, Issue:11

    Topics: 3-Oxoacyl-(Acyl-Carrier-Protein) Reductase; Alcohol Oxidoreductases; Animals; Antimalarials; Catechin; Cells, Cultured; Chloroquine; Drug Resistance; Enoyl-(Acyl-Carrier-Protein) Reductase (NADH); Fatty Acids; Flavones; Flavonoids; Humans; Hydro-Lyases; Kinetics; Luteolin; Phenols; Plasmodium falciparum; Polyphenols; Structure-Activity Relationship

2006
Reliability of bond dissociation enthalpy calculated by the PM6 method and experimental TEAC values in antiradical QSAR of flavonoids.
    Bioorganic & medicinal chemistry, 2010, Jan-01, Volume: 18, Issue:1

    Topics: Flavonoids; Free Radical Scavengers; Models, Biological; Quantitative Structure-Activity Relationship; Quantum Theory; Software; Thermodynamics

2010
New inhibitors for expression of IgE receptor on human mast cell.
    Bioorganic & medicinal chemistry letters, 2010, Apr-01, Volume: 20, Issue:7

    Topics: Anthocyanins; Anti-Allergic Agents; Catechin; Cell Line; Flavones; Flavonoids; Gene Expression; Humans; Hypersensitivity; Mast Cells; Receptors, IgE

2010
The lipogenesis pathway as a cancer target.
    Journal of medicinal chemistry, 2011, Aug-25, Volume: 54, Issue:16

    Topics: Acetyl-CoA Carboxylase; Animals; Antineoplastic Agents; ATP Citrate (pro-S)-Lyase; Biosynthetic Pathways; Fatty Acid Synthases; Fatty Acids; Humans; Lipogenesis; Models, Chemical; Molecular Structure; Neoplasms

2011
Comparative study on antioxidant capacity of flavonoids and their inhibitory effects on oleic acid-induced hepatic steatosis in vitro.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:9

    Topics: Antioxidants; Cell Line; Fatty Liver; Flavonoids; Humans; In Vitro Techniques; Oleic Acid; Reactive Oxygen Species; Triglycerides

2011
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
    Bioorganic & medicinal chemistry, 2012, Nov-15, Volume: 20, Issue:22

    Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship

2012
Naturally occurring polyphenolic inhibitors of amyloid beta aggregation.
    Bioorganic & medicinal chemistry letters, 2014, Jul-15, Volume: 24, Issue:14

    Topics: Amyloid beta-Peptides; Crystallography, X-Ray; Dose-Response Relationship, Drug; Humans; Models, Molecular; Molecular Structure; Peptide Fragments; Polyphenols; Protein Aggregates; Protein Aggregation, Pathological; Structure-Activity Relationship

2014
Defining Key Structural Determinants for the Pro-osteogenic Activity of Flavonoids.
    Journal of natural products, 2015, Nov-25, Volume: 78, Issue:11

    Topics: Cell Differentiation; Flavonoids; Humans; Mesenchymal Stem Cells; Molecular Structure; Osteogenesis; Signal Transduction; Structure-Activity Relationship

2015
Flavones Inhibit the Activity of AKR1B10, a Promising Therapeutic Target for Cancer Treatment.
    Journal of natural products, 2015, Nov-25, Volume: 78, Issue:11

    Topics: Aldehyde Reductase; Aldo-Keto Reductases; Apigenin; Daunorubicin; Enzyme Inhibitors; Flavones; Flavonoids; HCT116 Cells; Humans; Luteolin; Molecular Conformation; Molecular Structure; Neoplasms

2015
Protective effects of kaempferol against reactive oxygen species-induced hemolysis and its antiproliferative activity on human cancer cells.
    European journal of medicinal chemistry, 2016, May-23, Volume: 114

    Topics: Antioxidants; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Erythrocytes; HeLa Cells; Hemolysis; Humans; Kaempferols; MCF-7 Cells; Molecular Structure; Neoplasms; Protective Agents; Reactive Oxygen Species; Structure-Activity Relationship

2016
Flavonoids and their derivatives with β-amyloid aggregation inhibitory activity from the leaves and twigs of Pithecellobium clypearia Benth.
    Bioorganic & medicinal chemistry letters, 2017, 11-01, Volume: 27, Issue:21

    Topics: Amyloid beta-Peptides; Cell Line, Tumor; Cell Survival; Fabaceae; Flavonoids; Humans; Hydrogen Peroxide; Magnetic Resonance Spectroscopy; Molecular Conformation; Neuroprotective Agents; Plant Leaves; Plant Stems; Spectrometry, Mass, Electrospray Ionization

2017
Unraveling the anti-influenza effect of flavonoids: Experimental validation of luteolin and its congeners as potent influenza endonuclease inhibitors.
    European journal of medicinal chemistry, 2020, Dec-15, Volume: 208

    Topics: Antiviral Agents; Crystallography, X-Ray; Drug Evaluation, Preclinical; Endonucleases; Enzyme Assays; Enzyme Inhibitors; Flavonoids; Influenza A virus; Microbial Sensitivity Tests; Molecular Structure; Protein Binding; Protein Domains; RNA-Dependent RNA Polymerase; Structure-Activity Relationship; Viral Proteins

2020
A role of flavonoids in cytochrome c-cardiolipin interactions.
    Bioorganic & medicinal chemistry, 2021, 03-01, Volume: 33

    Topics: Cardiolipins; Cytochromes c; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flavonoids; Humans; Molecular Structure; Oxidation-Reduction; Structure-Activity Relationship

2021
Enhanced anti-tumor activity by the combination of the natural compounds (-)-epigallocatechin-3-gallate and luteolin: potential role of p53.
    The Journal of biological chemistry, 2010, Nov-05, Volume: 285, Issue:45

    Topics: Animals; Anticarcinogenic Agents; Apoptosis; Ataxia Telangiectasia Mutated Proteins; Caspase 3; Catechin; Cell Cycle Proteins; Cell Line, Tumor; DNA Damage; DNA-Binding Proteins; Drug Synergism; Gene Expression Regulation, Neoplastic; Head and Neck Neoplasms; Humans; Ki-67 Antigen; Luteolin; Mice; Mice, Nude; Mitochondria; Neoplasm Transplantation; Phosphorylation; Protein Serine-Threonine Kinases; Protein Stability; Tumor Suppressor Protein p53; Tumor Suppressor Proteins; Xenograft Model Antitumor Assays

2010
Biochemical characterization of epigallocatechin-3-gallate as an effective stimulator for the phosphorylation of its binding proteins by glycogen synthase kinase-3β in vitro.
    Biological & pharmaceutical bulletin, 2010, Volume: 33, Issue:12

    Topics: Animals; Camellia sinensis; Carrier Proteins; Catechin; Cattle; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Intercellular Signaling Peptides and Proteins; Luteolin; Myelin Basic Protein; Nerve Tissue Proteins; Phosphorylation; Plant Extracts; Quercetin; Rats; tau Proteins; Vimentin

2010
A profile of bioactive compounds of Rumex vesicarius L.
    Journal of food science, 2011, Volume: 76, Issue:8

    Topics: 1-Butanol; alpha-Tocopherol; Antioxidants; Apigenin; beta Carotene; Catechin; Chromatography, High Pressure Liquid; Egypt; Food Analysis; Fruit; Glucosides; Herbal Medicine; Luteolin; Phenols; Plant Extracts; Plant Leaves; Plant Roots; Quercetin; Rumex; Silymarin; Tandem Mass Spectrometry

2011
Opposite effects of quercetin, luteolin, and epigallocatechin gallate on insulin sensitivity under normal and inflammatory conditions in mice.
    Inflammation, 2013, Volume: 36, Issue:1

    Topics: 3T3 Cells; Adipose Tissue; Animals; Biological Transport; Blood Glucose; Catechin; Cell Line; Culture Media, Conditioned; Glucose; Glucose Tolerance Test; I-kappa B Kinase; Inflammation; Insulin Receptor Substrate Proteins; Insulin Resistance; Luteolin; Macrophages; Male; Mice; Mice, Inbred ICR; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Quercetin

2013
Plant polyphenol induced cell death in human cancer cells involves mobilization of intracellular copper ions and reactive oxygen species generation: a mechanism for cancer chemopreventive action.
    Molecular nutrition & food research, 2014, Volume: 58, Issue:3

    Topics: Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Apigenin; Apoptosis; Catechin; Cell Death; Cell Line, Tumor; Cell Proliferation; Chelating Agents; Copper; Drug Screening Assays, Antitumor; Humans; Luteolin; Phenanthrolines; Polyphenols; Reactive Oxygen Species; Resveratrol; Stilbenes

2014
Effects of the vegetable polyphenols epigallocatechin-3-gallate, luteolin, apigenin, myricetin, quercetin, and cyanidin in primary cultures of human retinal pigment epithelial cells.
    Molecular vision, 2014, Volume: 20

    Topics: Anthocyanins; Apigenin; Catechin; Cell Death; Cell Proliferation; Cell Survival; Cells, Cultured; Chemotaxis; DNA Fragmentation; Epithelial Cells; Flavonoids; Gene Expression Regulation; Humans; Imidazoles; Indoles; Intracellular Space; Luteolin; Phosphorylation; Polyphenols; Quercetin; Retinal Pigment Epithelium; RNA, Messenger; Signal Transduction; Vascular Endothelial Growth Factor A; Vegetables

2014
In vitro anti-osteoporosis properties of diverse Korean Drynariae rhizoma phenolic extracts.
    Nutrients, 2014, Apr-24, Volume: 6, Issue:4

    Topics: Animals; Antioxidants; Catechin; Cell Proliferation; Cells, Cultured; Chlorogenic Acid; Chromatography, High Pressure Liquid; Coumaric Acids; Emodin; Hydroxybenzoates; Luteolin; Mice; Osteoporosis; Phloroglucinol; Plant Extracts; Plants, Medicinal; Polypodiaceae; Quercetin; Republic of Korea

2014
Quercetin, luteolin, and epigallocatechin gallate promote glucose disposal in adipocytes with regulation of AMP-activated kinase and/or sirtuin 1 activity.
    Planta medica, 2014, Volume: 80, Issue:12

    Topics: 3T3-L1 Cells; Adipocytes; Adipokines; AMP-Activated Protein Kinases; Animals; Anti-Inflammatory Agents; Catechin; Glucose; Hypoglycemic Agents; Insulin; Luteolin; Mice; NF-kappa B; Niacinamide; Phosphorylation; Plant Extracts; Proto-Oncogene Proteins c-akt; Quercetin; Signal Transduction; Sirtuin 1

2014
The polyphenols (-)-epigallocatechin-3-gallate and luteolin synergistically inhibit TGF-β-induced myofibroblast phenotypes through RhoA and ERK inhibition.
    PloS one, 2014, Volume: 9, Issue:10

    Topics: Catechin; Cell Line; Drug Synergism; Extracellular Signal-Regulated MAP Kinases; Humans; Luteolin; Myofibroblasts; Phenotype; rhoA GTP-Binding Protein; Transforming Growth Factor beta

2014
Quercetin, luteolin and epigallocatechin gallate alleviate TXNIP and NLRP3-mediated inflammation and apoptosis with regulation of AMPK in endothelial cells.
    European journal of pharmacology, 2014, Dec-15, Volume: 745

    Topics: AMP-Activated Protein Kinases; Apoptosis; Carrier Proteins; Catechin; Cell Line; Endoplasmic Reticulum Stress; Endothelial Cells; Endothelin-1; Gene Expression; Human Umbilical Vein Endothelial Cells; Humans; Inflammasomes; Inflammation; Luteolin; NLR Family, Pyrin Domain-Containing 3 Protein; Oxidative Stress; Palmitic Acid; Protein Kinase Inhibitors; Quercetin

2014
Correlation between the potency of flavonoids for cytochrome c reduction and inhibition of cardiolipin-induced peroxidase activity.
    BioFactors (Oxford, England), 2017, May-06, Volume: 43, Issue:3

    Topics: Animals; Anthocyanins; Ascorbic Acid; Cardiolipins; Catechin; Cytochromes c; Diphenylhexatriene; Flavonoids; Fluorescent Dyes; Horses; Kaempferols; Luteolin; Oxidation-Reduction; Peroxidases; Phosphatidylcholines; Protein Binding; Protein Conformation; Quercetin; Reducing Agents; Spectrometry, Fluorescence; Static Electricity; Unilamellar Liposomes

2017
Modulatory influences of antiviral bioactive compounds on cell viability, mRNA and protein expression of cytochrome P450 3A4 and P-glycoprotein in HepG2 and HEK293 cells.
    Bioorganic chemistry, 2021, Volume: 107

    Topics: Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Catechin; Cell Survival; Cytochrome P-450 CYP3A; Ellagic Acid; Gene Expression Regulation; HEK293 Cells; Hep G2 Cells; Humans; Luteolin; Plants; Protein Binding; RNA, Messenger

2021
Antimicrobial synergistic effects of apigenin, (-)-epigallocatechin-3-gallate, myricetin and luteolin in combination with some antibiotics.
    Annals of agricultural and environmental medicine : AAEM, 2023, Mar-31, Volume: 30, Issue:1

    Topics: Anti-Bacterial Agents; Apigenin; Drug Synergism; Flavonoids; Luteolin; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests

2023