Page last updated: 2024-08-24

epigallocatechin gallate and interleukin-8

epigallocatechin gallate has been researched along with interleukin-8 in 29 studies

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (20.69)29.6817
2010's21 (72.41)24.3611
2020's2 (6.90)2.80

Authors

AuthorsStudies
Chen, PC; Denenberg, AG; Malhotra, V; Odoms, K; Wheeler, DS; Wong, HR1
Denis, A; Schmitt, D; Trompezinski, S; Viac, J1
Catravas, JD; Denenberg, A; Malhotra, V; Odoms, K; Wheeler, DS; Wong, HR1
Drewe, J; Porath, D; Riegger, C; Schwager, J1
Hong, SH; Jeong, HJ; Kim, HM; Kim, SH; Kim, SY; Shin, HY; Shin, TY; Um, JY1
An, NH; Hong, SH; Jeong, HJ; Kim, HM; Kim, SJ; Lee, HJ; Lee, KM; Myung, NY; Park, SK; Um, JY; Yang, WM1
Bonneville, M; Denis, A; Pernet, I; Schmitt, D; Trompezinski, S; Viac, J1
Huang, GS; Lee, CH; Lee, HS; Su, SL; Tseng, CY1
Hirao, K; Hosokawa, Y; Matsuo, T; Mukai, K; Nakanishi, T; Yumoto, H1
Bomser, JA; Ferruzzi, MG; Green, R; Gutierrez-Orozco, F; Neilson, AP; Stephens, BR1
Biasi, F; Chiarpotto, E; Leonarduzzi, G; Maina, M; Mascia, C; Poli, G1
Akhtar, N; Haqqi, TM1
Brückner, M; Domschke, W; Kucharzik, T; Lügering, A; Westphal, S1
Ender, SA; Hönicke, AS; Radons, J1
Choi, DK; Hwang, YL; Im, M; Kim, CD; Kim, SY; Lee, JH; Lee, Y; Seo, YJ; Sohn, KC; Zouboulis, CC1
He, L; Le, AD; Li, X; Shi, J; Tang, X; Zhang, E; Zhang, Q; Zhou, K1
Bona, G; Bossi, A; De Gregorio, F; De Rosa, G; De Stefano, D; Esposito, S; Grassia, R; Guido, S; Kroemer, G; Leone, CA; Maiuri, L; Maiuri, MC; Mehta, A; Pettoello-Mantovani, M; Pinna, LA; Raia, V; Salvadori, L; Sepe, A; Tosco, A; Venerando, A; Villella, VR; Zolin, A1
Ahmed, S; Chourasia, M; Riegsecker, S; Singh, AK; Umar, S1
Grenier, D; Lombardo Bedran, TB; Morin, MP; Palomari Spolidorio, D1
Lee, JY; Lee, SB; Paik, JS; Yang, SW; Yun, M1
Bona, G; Buonpensiero, P; De Gregorio, F; De Rosa, G; De Stefano, D; Di Pasqua, A; Esposito, S; Ferrari, E; Grassia, R; Guido, S; Kroemer, G; Leone, CA; Lusa, S; Maiuri, L; Maiuri, MC; Mehta, A; Raia, V; Salvadori, L; Sana, I; Sepe, A; Stoll, G; Tosco, A1
Allijn, IE; Beukelman, KJ; de Winther, MP; Quarles van Ufford, LC; Schiffelers, RM; Storm, G; Vaessen, SF1
Fan, KJ; Gu, J; Hu, J; Qin, CY; Xiao, Z; Xu, F; Zhang, EY; Zhang, HW1
Ahmed, S; Chourasia, M; Fechtner, S; Singh, A1
Fan, KJ; Gu, J; Hu, J; Liang, HM; Qin, CY; Shen, JY; Xiao, ZH; Xu, F; Zhang, EY; Zhang, HW1
Chen, H; Du, G; Ge, M; Luo, F; Xiao, Y; Zeng, F1
Ip, MSM; Liang, Y; Mak, JCW1
Jeong, HJ; Kang, HG; Kim, HM; Kim, HY; Nam, SY1
Ge, J; Kong, J; Li, Y; Ma, K1

Trials

2 trial(s) available for epigallocatechin gallate and interleukin-8

ArticleYear
Restoration of CFTR function in patients with cystic fibrosis carrying the F508del-CFTR mutation.
    Autophagy, 2014, Volume: 10, Issue:11

    Topics: Adaptor Proteins, Signal Transducing; Administration, Oral; Adolescent; Adult; Animals; Apoptosis Regulatory Proteins; Beclin-1; Catechin; Cell Membrane; Child; Chlorides; Cystamine; Cysteamine; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Female; Homozygote; Humans; Interleukin-8; Male; Membrane Proteins; Mice; Mice, Inbred CFTR; Mice, Transgenic; Mutation; Phenotype; Pilot Projects; Sequestosome-1 Protein; Tumor Necrosis Factor-alpha; Young Adult

2014
A novel treatment of cystic fibrosis acting on-target: cysteamine plus epigallocatechin gallate for the autophagy-dependent rescue of class II-mutated CFTR.
    Cell death and differentiation, 2016, Volume: 23, Issue:8

    Topics: Adolescent; Animals; Autophagy; Biomarkers; Catechin; Child; Cysteamine; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Disease Models, Animal; Drug Therapy, Combination; Homozygote; Humans; Interleukin-8; Lung; Mice; Mice, Knockout; Mutation; Sputum; Tumor Necrosis Factor-alpha

2016

Other Studies

27 other study(ies) available for epigallocatechin gallate and interleukin-8

ArticleYear
A green tea-derived polyphenol, epigallocatechin-3-gallate, inhibits IkappaB kinase activation and IL-8 gene expression in respiratory epithelium.
    Inflammation, 2002, Volume: 26, Issue:5

    Topics: Antioxidants; Catechin; Enzyme Activation; Flavonoids; Humans; I-kappa B Kinase; Interleukin-8; NF-kappa B; Phenols; Polymers; Protein Serine-Threonine Kinases; Respiratory Mucosa; RNA, Messenger; Tea; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha

2002
Comparative effects of polyphenols from green tea (EGCG) and soybean (genistein) on VEGF and IL-8 release from normal human keratinocytes stimulated with the proinflammatory cytokine TNFalpha.
    Archives of dermatological research, 2003, Volume: 295, Issue:3

    Topics: Angiogenesis Inhibitors; Catechin; Cell Division; Cells, Cultured; Down-Regulation; Genistein; Growth Inhibitors; Humans; Interleukin-8; Keratinocytes; Plant Extracts; Tea; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A

2003
Epigallocatechin-3-gallate, a green tea-derived polyphenol, inhibits IL-1 beta-dependent proinflammatory signal transduction in cultured respiratory epithelial cells.
    The Journal of nutrition, 2004, Volume: 134, Issue:5

    Topics: Anti-Inflammatory Agents; Catechin; Cell Line, Tumor; Enzyme Activation; Flavonoids; Gene Expression Regulation; Humans; I-kappa B Kinase; Inflammation Mediators; Interleukin-1; Interleukin-1 Receptor-Associated Kinases; Interleukin-8; Isoenzymes; NF-kappa B; Phenols; Phosphorylation; Polyphenols; Protein Kinases; Protein Serine-Threonine Kinases; Respiratory Mucosa; Signal Transduction; Tea; Transcription Factor RelA

2004
Epigallocatechin-3-gallate impairs chemokine production in human colon epithelial cell lines.
    The Journal of pharmacology and experimental therapeutics, 2005, Volume: 315, Issue:3

    Topics: Antioxidants; Catechin; Cell Line, Tumor; Cell Survival; Chemokines; Colon; Colonic Neoplasms; Dinoprostone; Enzyme-Linked Immunosorbent Assay; Epithelial Cells; HT29 Cells; Humans; Interleukin-8; Kinetics; Macrophage Inflammatory Proteins; Reverse Transcriptase Polymerase Chain Reaction; Tumor Necrosis Factor-alpha; Up-Regulation

2005
Epigallocatechin-3-gallate inhibits secretion of TNF-alpha, IL-6 and IL-8 through the attenuation of ERK and NF-kappaB in HMC-1 cells.
    International archives of allergy and immunology, 2007, Volume: 142, Issue:4

    Topics: Calcimycin; Calcium; Catechin; Cell Line, Tumor; Extracellular Signal-Regulated MAP Kinases; Humans; Interleukin-6; Interleukin-8; Ionophores; NF-kappa B; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha

2007
Epigallocatechin-3-gallate suppresses NF-kappaB activation and phosphorylation of p38 MAPK and JNK in human astrocytoma U373MG cells.
    The Journal of nutritional biochemistry, 2007, Volume: 18, Issue:9

    Topics: Amyloid beta-Peptides; Anti-Inflammatory Agents; Astrocytoma; Catechin; Cyclooxygenase 2; Dinoprostone; Humans; Interleukin-1beta; Interleukin-6; Interleukin-8; JNK Mitogen-Activated Protein Kinases; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Peptide Fragments; Phosphorylation; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A

2007
Gingko biloba extract reduces VEGF and CXCL-8/IL-8 levels in keratinocytes with cumulative effect with epigallocatechin-3-gallate.
    Archives of dermatological research, 2010, Volume: 302, Issue:3

    Topics: Anti-Inflammatory Agents; Catechin; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Down-Regulation; Ginkgo biloba; Humans; Interleukin-8; Keratinocytes; Male; Plant Extracts; Plant Leaves; Time Factors; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A

2010
Effects of (-)-epigallocatechin-3-gallate on cyclooxygenase 2, PGE(2), and IL-8 expression induced by IL-1beta in human synovial fibroblasts.
    Rheumatology international, 2010, Volume: 30, Issue:9

    Topics: Aged; Aged, 80 and over; Catechin; Cyclooxygenase 2; Enzyme-Linked Immunosorbent Assay; Fibroblasts; Genes; Humans; Interleukin-1beta; Interleukin-8; Middle Aged; Osteoarthritis; Prostaglandins E; Reverse Transcriptase Polymerase Chain Reaction; Synovial Membrane; Up-Regulation

2010
Anti-inflammatory effect of catechin on cultured human dental pulp cells affected by bacteria-derived factors.
    European journal of oral sciences, 2010, Volume: 118, Issue:2

    Topics: Anti-Inflammatory Agents; Antioxidants; Catechin; Cells, Cultured; Dental Pulp; Escherichia coli; Flow Cytometry; Humans; Intercellular Adhesion Molecule-1; Interleukin-6; Interleukin-8; Lipopolysaccharides; Peptidoglycan; Reverse Transcriptase Polymerase Chain Reaction; Staphylococcus aureus; Time Factors; Vascular Cell Adhesion Molecule-1

2010
Green and black tea inhibit cytokine-induced IL-8 production and secretion in AGS gastric cancer cells via inhibition of NF-κB activity.
    Planta medica, 2010, Volume: 76, Issue:15

    Topics: Camellia sinensis; Catechin; Cell Line, Tumor; Chromatography, Liquid; Humans; Interleukin-1beta; Interleukin-8; MAP Kinase Signaling System; Mass Spectrometry; NF-kappa B; Plant Extracts; Stomach Neoplasms; Tea

2010
Proinflammatory effect of cholesterol and its oxidation products on CaCo-2 human enterocyte-like cells: effective protection by epigallocatechin-3-gallate.
    Free radical biology & medicine, 2010, Dec-15, Volume: 49, Issue:12

    Topics: Antioxidants; Apoptosis; Caco-2 Cells; Catechin; Cholesterol; Enterocytes; Enzyme Activation; Humans; Hydroxycholesterols; Inflammation Mediators; Interleukin-8; Ketocholesterols; NADPH Oxidases; Onium Compounds; Up-Regulation

2010
Epigallocatechin-3-gallate suppresses the global interleukin-1beta-induced inflammatory response in human chondrocytes.
    Arthritis research & therapy, 2011, Jun-17, Volume: 13, Issue:3

    Topics: Aged; Antioxidants; Catechin; Chondrocytes; Cytoprotection; Drug Interactions; Gene Expression; Humans; Intercellular Signaling Peptides and Proteins; Interleukin-1 Receptor-Associated Kinases; Interleukin-1beta; Interleukin-6; Interleukin-8; MAP Kinase Signaling System; Middle Aged; NF-kappa B; Nitrites; Osteoarthritis; Primary Cell Culture; TNF Receptor-Associated Factor 6; Tumor Necrosis Factor-alpha

2011
Green tea polyphenol epigallocatechin-3-gallate shows therapeutic antioxidative effects in a murine model of colitis.
    Journal of Crohn's & colitis, 2012, Volume: 6, Issue:2

    Topics: Alkaloids; Analysis of Variance; Animals; Antioxidants; Benzodioxoles; Catechin; Colitis; Dextran Sulfate; Female; Glutathione Peroxidase; HT29 Cells; Humans; Interleukin-8; Malondialdehyde; Mice; Mice, Inbred C57BL; Oxidative Stress; Peroxidase; Piperidines; Polyunsaturated Alkamides; Reactive Oxygen Species; Superoxide Dismutase; Weight Loss

2012
Combined administration of EGCG and IL-1 receptor antagonist efficiently downregulates IL-1-induced tumorigenic factors in U-2 OS human osteosarcoma cells.
    International journal of oncology, 2012, Volume: 41, Issue:2

    Topics: Antineoplastic Agents; Caspase 3; Catechin; Cell Line, Tumor; Cell Survival; Cell Transformation, Neoplastic; Drug Synergism; Enzyme Activation; Humans; Interleukin 1 Receptor Antagonist Protein; Interleukin-1; Interleukin-6; Interleukin-8; Matrix Metalloproteinase 2; Osteosarcoma; Receptors, Interleukin-1; Vascular Endothelial Growth Factor A

2012
Epigallocatechin-3-gallate suppresses IGF-I-induced lipogenesis and cytokine expression in SZ95 sebocytes.
    The Journal of investigative dermatology, 2012, Volume: 132, Issue:12

    Topics: Acne Vulgaris; Administration, Topical; Animals; Anti-Inflammatory Agents; Apoptosis; Catechin; Cell Line, Transformed; Cell Proliferation; Cytokines; Ear Auricle; Female; Humans; Insulin-Like Growth Factor I; Interleukin-1; Interleukin-6; Interleukin-8; Lipogenesis; Rabbits; Sebaceous Glands; Sebum; Signal Transduction

2012
(-)-Epigallocatechin-3-gallate inhibits human papillomavirus (HPV)-16 oncoprotein-induced angiogenesis in non-small cell lung cancer cells by targeting HIF-1α.
    Cancer chemotherapy and pharmacology, 2013, Volume: 71, Issue:3

    Topics: Angiogenesis Inhibitors; Animals; Blotting, Western; Carcinoma, Non-Small-Cell Lung; Catechin; Cell Line, Tumor; Enzyme-Linked Immunosorbent Assay; Gene Expression; Human papillomavirus 16; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Interleukin-8; Lung Neoplasms; Male; Mice; Mice, Inbred BALB C; Neovascularization, Pathologic; Oncogene Proteins; Oncogene Proteins, Viral; Papillomavirus E7 Proteins; Platelet Endothelial Cell Adhesion Molecule-1; Proto-Oncogene Proteins c-akt; Real-Time Polymerase Chain Reaction; Repressor Proteins; Signal Transduction; Transfection; Vascular Endothelial Growth Factor A

2013
Regulation of Transforming Growth Factor β-Activated Kinase Activation by Epigallocatechin-3-Gallate in Rheumatoid Arthritis Synovial Fibroblasts: Suppression of K(63) -Linked Autoubiquitination of Tumor Necrosis Factor Receptor-Associated Factor 6.
    Arthritis & rheumatology (Hoboken, N.J.), 2016, Volume: 68, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Arthritis, Rheumatoid; Blotting, Western; Catechin; Disease Models, Animal; Female; Fibroblasts; Humans; Immunoprecipitation; In Vitro Techniques; Interleukin-1 Receptor-Associated Kinases; Interleukin-1beta; Interleukin-6; Interleukin-8; Lysine; MAP Kinase Kinase Kinases; Molecular Docking Simulation; Proteasome Endopeptidase Complex; Protein Processing, Post-Translational; Rats; Rats, Inbred Lew; Synovial Membrane; TNF Receptor-Associated Factor 6; Ubiquitination

2016
Black Tea Extract and Its Theaflavin Derivatives Inhibit the Growth of Periodontopathogens and Modulate Interleukin-8 and β-Defensin Secretion in Oral Epithelial Cells.
    PloS one, 2015, Volume: 10, Issue:11

    Topics: beta-Defensins; Biflavonoids; Catechin; Cell Line; Epithelial Cells; Humans; Interleukin-8; Lipopolysaccharides; Microbial Sensitivity Tests; Mouth; Plant Extracts; Porphyromonas gingivalis; Tea

2015
The Effect of (-)-Epigallocatechin-3-Gallate on IL-1β Induced IL-8 Expression in Orbital Fibroblast from Patients with Thyroid-Associated Ophthalmopathy.
    PloS one, 2016, Volume: 11, Issue:2

    Topics: Antioxidants; Catechin; Fibroblasts; Graves Ophthalmopathy; Humans; Interleukin-1beta; Interleukin-8; MAP Kinase Signaling System; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Reactive Oxygen Species

2016
Head-to-Head Comparison of Anti-Inflammatory Performance of Known Natural Products In Vitro.
    PloS one, 2016, Volume: 11, Issue:5

    Topics: Acetophenones; Animals; Anti-Inflammatory Agents; Berberine; Biological Products; Blood Platelets; Caco-2 Cells; Catechin; Cell Line; Curcumin; Humans; Interleukin-6; Interleukin-8; Macrophages; Mice; Neutrophils; Platelet Activation; Pravastatin; Prednisolone; Primary Cell Culture; Reactive Oxygen Species; Stilbenes; Tumor Necrosis Factor-alpha

2016
[Epigallocatechin-3-gallate Attenuates Myocardial Reperfusion Injury in Rats Through Activation of PI3K/Akt Signaling Pathway].
    Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2016, Volume: 47, Issue:3

    Topics: Animals; Catechin; Creatine Kinase; Interleukin-6; Interleukin-8; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Signal Transduction; Tumor Necrosis Factor-alpha; Up-Regulation

2016
Molecular insights into the differences in anti-inflammatory activities of green tea catechins on IL-1β signaling in rheumatoid arthritis synovial fibroblasts.
    Toxicology and applied pharmacology, 2017, 08-15, Volume: 329

    Topics: Anti-Inflammatory Agents; Antirheumatic Agents; Arthritis, Rheumatoid; Catalytic Domain; Catechin; Cells, Cultured; Cyclooxygenase 2 Inhibitors; Fibroblasts; Humans; Interleukin-1beta; Interleukin-6; Interleukin-8; MAP Kinase Kinase Kinases; Matrix Metalloproteinase 2; Molecular Docking Simulation; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Phytotherapy; Plants, Medicinal; Protein Binding; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-jun; Signal Transduction; Synovial Membrane; Tea

2017
Mitochondrial DNA‑induced inflammatory damage contributes to myocardial ischemia reperfusion injury in rats: Cardioprotective role of epigallocatechin.
    Molecular medicine reports, 2017, Volume: 16, Issue:5

    Topics: Androstadienes; Animals; Catechin; Creatine Kinase; DNA, Mitochondrial; Enzyme-Linked Immunosorbent Assay; Interleukin-6; Interleukin-8; L-Lactate Dehydrogenase; Male; Myocardial Reperfusion Injury; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protective Agents; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Signal Transduction; Tumor Necrosis Factor-alpha; Wortmannin

2017
Multiple antiviral approaches of (-)-epigallocatechin-3-gallate (EGCG) against porcine reproductive and respiratory syndrome virus infection in vitro.
    Antiviral research, 2018, Volume: 158

    Topics: Animals; Antiviral Agents; Catechin; Cell Line; Chlorocebus aethiops; Cytokines; Down-Regulation; Interleukin-6; Interleukin-8; Macrophages, Alveolar; Porcine Reproductive and Respiratory Syndrome; Porcine respiratory and reproductive syndrome virus; Receptors, Virus; Swine; Time Factors; Tumor Necrosis Factor-alpha; Viral Proteins; Virion; Virus Attachment; Virus Replication

2018
(-)-Epigallocatechin-3-gallate suppresses cigarette smoke-induced inflammation in human cardiomyocytes via ROS-mediated MAPK and NF-κB pathways.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2019, Volume: 58

    Topics: Antioxidants; Apoptosis; Catechin; Cell Line; Humans; Interleukin-8; MAP Kinase Signaling System; Myocarditis; Myocytes, Cardiac; NF-kappa B; Oxidative Stress; Reactive Oxygen Species; Signal Transduction; Smoking

2019
Blockade of RANKL/RANK signaling pathway by epigallocatechin gallate alleviates mast cell-mediated inflammatory reactions.
    International immunopharmacology, 2020, Volume: 88

    Topics: Caspase 1; Catechin; Cell Line; Cell Survival; Cytokines; Elafin; Histamine; Humans; Inflammation; Interleukin-1beta; Interleukin-6; Interleukin-8; Mast Cells; Mitogen-Activated Protein Kinases; NF-kappa B; RANK Ligand; Signal Transduction; Thymic Stromal Lymphopoietin

2020
Epigallocatechin-3-gallate exerts protective effect on epithelial function via PI3K/AKT signaling in thrombosis.
    Microvascular research, 2022, Volume: 144

    Topics: Animals; Apoptosis; Catechin; Interleukin-6; Interleukin-8; Myocardial Reperfusion Injury; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats; Signal Transduction; Superoxide Dismutase; Thrombosis; Tumor Necrosis Factor-alpha

2022