Page last updated: 2024-08-18

epichlorohydrin and mci-196

epichlorohydrin has been researched along with mci-196 in 46 studies

Research

Studies (46)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's31 (67.39)29.6817
2010's15 (32.61)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Honda, Y; Nakano, M1
Hayashi, Y; Inaba, M; Kubota, H; Nakamura, K; Okamoto, S; Tani, M; Yokohama, S1
Hasegawa, Y; Hojo, M; Ogasawara, T; Ohashi, M; Sato, A; Takikawa, H1
Onishi, T; Sano, N; Takikawa, H1
Matsuzaki, Y1
Sano, N; Takeuchi, A; Takikawa, H1
Date, T; Kawashita, Y; Morita, K; Satake, N; Shigematsu, T1
Daida, H; Miyauchi, K; Shimada, K1
Akiba, T; Nihei, H; Nitta, K1
Mori, C; Saito, Y; Sakurai, K; Todaka, E1
Abe, Y; Kushiya, F; Nakasaki, T; Nobori, T; Noda, M; Ooi, K; Sakaguchi, A; Sakurai, Y; Shiku, H; Tsukada, T; Wada, H1
Fukami, K; Haramaki, N; Iida, S; Ikeda, H; Imaizumi, T; Matsuoka, H; Murase, E; Sugano, R; Umei, H1
Higashikata, T; Inazu, A; Kawashiri, MA; Kobayashi, J; Koizumi, J; Mabuchi, H; Nohara, A1
Kanai, S; Miyashita, Y; Oyama, T; Sasaki, H; Shirai, K1
Kamezaki, F; Kubara, T; Miyamoto, M; Nakashima, Y; Tanaka, S; Tasaki, H; Tsutsui, M; Yamashita, K1
Honda, Y; Kochi, M; Kuratsu, J; Kuroda, J; Makino, K; Nakamura, H; Ushio, Y1
Gylling, H; Miettinen, TA1
Bujo, H; Fukata, H; Mori, C; Saito, Y; Sakurai, K; Todaka, E1
Kadonosono, K; Okamura, A; Takano, T; Utsunomiya, H; Yamakawa, T1
Futami, S; Igari, Y; Kigawa, Y; Matsumura, N; Nakano, H; Oba, K; Ouchi, M; Suzuki, K; Suzuki, T; Watanabe, K1
Babaya, N; Fujisawa, T; Hiromine, Y; Ikegami, H; Itoi-Babaya, M; Kawabata, Y; Kobayashi, M; Nojima, K; Noso, S; Ogihara, T; Shibata, M; Yamaji, K1
Haramaki, N; Ikeda, H; Imaizumi, T; Katoh, A; Matsuoka, H; Sugano, R; Takenaka, K; Yamagishi, S1
Futami-Suda, S; Igari, Y; Kigawa, Y; Matsumura, N; Nakano, H; Oba, K; Ouchi, M; Suzuki, K; Suzuki, T; Watanabe, K1
Kakeya, T; Nagao, T; Nishimaki-Mogami, T; Okuhira, K; Sato, R; Shigemoto-Mogami, Y; Suzuki, K; Tamehiro, N1
Futami-Suda, S; Igari, Y; Kigawa, Y; Matsumura, N; Nakano, H; Oba, K; Ouchi, M; Suzuki, K; Suzuki, T; Watanabe, K; Yasuoka, H1
Amioka, K; Furuta, Y; Wada, I1
Fukusato, T; Kodama, H; Mori, Y; Takikawa, H; Tanaka, A; Uegaki, S1
Date, T; Funakoshi, S; Hashiguchi, J; Itoh, K; Kono, T; Kubo, H; Masaki, K; Nakano, H; Shigematsu, T; Tanaka, M; Uchino, J1
Futami-Suda, S; Kigawa, Y; Nakano, H; Norose, J; Oba, K; Ouchi, M; Sekimizu, K; Suzuki, K; Suzuki, T; Yoshimatsu, H1
Aso, Y; Inukai, T; Matsumoto, S; Suetsugu, M; Takebayashi, K1
Chiba, H; Fujii, S; Kishimoto, N; Sakuma, I; Tsutsui, H1
Miyamori, I; Suzuki, J; Takahashi, S; Zenimaru, Y1
Kadonosono, K; Kaneko, T; Kawaguchi, J; Morita, S; Shigematu, E; Terauchi, Y; Yamakawa, T1
Inagaki, K; Itoh, M; Kanayama, H; Katada, N; Kato, T; Sawai, Y1
Handelsman, Y1
Fujino, N; Hayashi, K; Inazu, A; Kawashiri, MA; Kobayashi, J; Konno, T; Mabuchi, H; Mori, M; Nakanishi, C; Noguchi, T; Nohara, A; Tada, H; Yamagishi, M1
Awata, T; Hosaka, T; Inukai, K; Katayama, S; Kurihara, S; Nakamoto, H; Neda, T; Ono, H1
Arita, E; Auwerx, J; Horai, Y; Houten, SM; Itoh, H; Kaneko-Iwasaki, N; Mataki, C; Morimoto, K; Murahashi, K; Sato, H; Schoonjans, K; Sugizaki, T; Suzuki, T; Watanabe, M1
Aoyama, J; Futami-Suda, S; Hashimoto, M; Igari, Y; Kigawa, Y; Nakano, H; Oba, K; Suzuki, T; Tsunoda-Kubota, M; Watanabe, K1
Kadonosono, K; Muraoka, T; Ogihara, K; Terauchi, Y; Utsunomiya, H; Yamakawa, T1
Hansen, M; Knop, FK; Sonne, DP1
Arakawa, H; Idota, Y; Kakinuma, C; Kasahara, F; Kato, T; Kobayashi, S; Kogure, Y; Miyajima, C; Ogawa, M; Ogihara, T; Yano, K1
Irie, J; Itoh, H; Morimoto, K; Sugizaki, T; Watanabe, M1
Inazu, A; Kawashiri, MA; Kobayashi, J; Mabuchi, H; Miyashita, K; Nakajima, K; Nohara, A; Tada, H; Yamagishi, M1
Furue, M; Honda, A; Imaji, M; Mitoma, C; Takao, Y; Todaka, T1
Gluud, LL; Hansen, M; Knop, FK; Mikkelsen, KH; Sonne, DP; Vilsbøll, T1

Reviews

4 review(s) available for epichlorohydrin and mci-196

ArticleYear
Drug-induced effects on cholesterol catabolism and bile acids.
    Current opinion in investigational drugs (London, England : 2000), 2006, Volume: 7, Issue:3

    Topics: Allylamine; Anticholesteremic Agents; Azetidines; Bile Acids and Salts; Cholesterol; Colesevelam Hydrochloride; Epichlorohydrin; Ezetimibe; Humans; Imidazoles; Resins, Synthetic

2006
Role of bile acid sequestrants in the treatment of type 2 diabetes.
    Diabetes care, 2011, Volume: 34 Suppl 2

    Topics: Allylamine; Bile Acids and Salts; Cholestyramine Resin; Colesevelam Hydrochloride; Colestipol; Diabetes Mellitus, Type 2; Epichlorohydrin; Hypolipidemic Agents; Imidazoles; Resins, Synthetic

2011
Bile acid sequestrants: glucose-lowering mechanisms and efficacy in type 2 diabetes.
    Current diabetes reports, 2014, Volume: 14, Issue:5

    Topics: Bile Acids and Salts; Blood Glucose; Diabetes Mellitus, Type 2; Epichlorohydrin; Female; Gastric Emptying; Glycated Hemoglobin; Humans; Hypercholesterolemia; Hypoglycemic Agents; Imidazoles; Incretins; Lipid Metabolism; Male; Resins, Synthetic; Signal Transduction; Treatment Outcome

2014
Bile acid sequestrants for glycemic control in patients with type 2 diabetes: A systematic review with meta-analysis of randomized controlled trials.
    Journal of diabetes and its complications, 2017, Volume: 31, Issue:5

    Topics: Bile Acids and Salts; Colesevelam Hydrochloride; Diabetes Mellitus, Type 2; Epichlorohydrin; Glycated Hemoglobin; Humans; Hyperglycemia; Hypoglycemia; Hypoglycemic Agents; Imidazoles; Randomized Controlled Trials as Topic; Reproducibility of Results; Resins, Synthetic; Sequestering Agents

2017

Trials

16 trial(s) available for epichlorohydrin and mci-196

ArticleYear
Effect of colestimide on intestinal absorption of ursodeoxycholic acid in men.
    International journal of clinical pharmacology and therapeutics, 2001, Volume: 39, Issue:12

    Topics: Adult; Anion Exchange Resins; Bile Acids and Salts; Cholagogues and Choleretics; Drug Interactions; Epichlorohydrin; Humans; Imidazoles; Intestinal Absorption; Male; Resins, Synthetic; Ursodeoxycholic Acid

2001
Colestimide can be used as a phosphate binder to treat uraemia in end-stage renal disease patients.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2003, Volume: 18 Suppl 3

    Topics: Adult; Anion Exchange Resins; Calcium; Cholesterol; Dose-Response Relationship, Drug; Drug Administration Schedule; Epichlorohydrin; Female; Humans; Imidazoles; Kidney Failure, Chronic; Male; Middle Aged; Phosphates; Resins, Synthetic; Uremia

2003
Effects of atorvastatin on serum lipids, lipoproteins, and hemostasis.
    American journal of hematology, 2005, Volume: 78, Issue:1

    Topics: Adult; Aged; Anion Exchange Resins; Atorvastatin; Electrophoresis, Agar Gel; Epichlorohydrin; Female; Hemostasis; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Imidazoles; Lipids; Lipoproteins; Male; Middle Aged; Pyrroles; Resins, Synthetic

2005
Polymorphonuclear leukocytes may impair endothelial function: results of crossover randomized study of lipid-lowering therapies.
    Arteriosclerosis, thrombosis, and vascular biology, 2005, Volume: 25, Issue:6

    Topics: Anticholesteremic Agents; Atherosclerosis; Cell Adhesion; Cholesterol, LDL; Cross-Over Studies; Endothelium, Vascular; Epichlorohydrin; Fatty Acids, Monounsaturated; Female; Fluvastatin; Humans; Hypercholesterolemia; Imidazoles; Indoles; Lipoproteins, LDL; Male; Middle Aged; Neutrophils; Nitric Oxide Synthase Type III; Phosphorylation; Resins, Synthetic; Serine; Superoxides; Vasodilation

2005
Efficacy of colestimide coadministered with atorvastatin in japanese patients with heterozygous familial hypercholesterolemia (FH).
    Circulation journal : official journal of the Japanese Circulation Society, 2005, Volume: 69, Issue:5

    Topics: Anion Exchange Resins; Anticholesteremic Agents; Atorvastatin; Cholesterol, LDL; Drug Therapy, Combination; Epichlorohydrin; Female; Heptanoic Acids; Humans; Hyperlipoproteinemia Type II; Imidazoles; Japan; Male; Middle Aged; Pyrroles; Resins, Synthetic

2005
Cross-over trial of intensive monotherapy with atorvastatin and combined therapy with atorvastatin and colestimide for Japanese familial hypercholesterolemia.
    Circulation journal : official journal of the Japanese Circulation Society, 2006, Volume: 70, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Anticholesteremic Agents; Atorvastatin; Cholesterol, LDL; Cross-Over Studies; Drug Therapy, Combination; Epichlorohydrin; Female; Genetic Carrier Screening; Heptanoic Acids; Humans; Hyperlipoproteinemia Type I; Imidazoles; Male; Middle Aged; Patient Dropouts; Pyrroles; Resins, Synthetic; Triglycerides

2006
Effect of colestimide therapy for glycemic control in type 2 diabetes mellitus with hypercholesterolemia.
    Endocrine journal, 2007, Volume: 54, Issue:1

    Topics: Aged; Anticholesteremic Agents; Blood Glucose; Diabetes Mellitus, Type 2; Epichlorohydrin; Female; Glycated Hemoglobin; Hemoglobins; Humans; Hypercholesterolemia; Imidazoles; Insulin Resistance; Male; Middle Aged; Pravastatin; Resins, Synthetic

2007
Blood glucose-lowering activity of colestimide in patients with type 2 diabetes and hypercholesterolemia: a case-control study comparing colestimide with acarbose.
    Journal of Nippon Medical School = Nippon Ika Daigaku zasshi, 2006, Volume: 73, Issue:5

    Topics: Acarbose; Aged; Blood Glucose; Diabetes Mellitus, Type 2; Epichlorohydrin; Female; Glycoside Hydrolase Inhibitors; Humans; Hypercholesterolemia; Hypoglycemic Agents; Imidazoles; Lipids; Male; Resins, Synthetic

2006
Fluvastatin alters platelet aggregability in patients with hypercholesterolemia: possible improvement of intraplatelet redox imbalance via HMG-CoA reductase.
    Arteriosclerosis, thrombosis, and vascular biology, 2007, Volume: 27, Issue:6

    Topics: Adult; Anion Exchange Resins; Blood Platelets; Cholesterol; Cross-Over Studies; Dose-Response Relationship, Drug; Epichlorohydrin; Fatty Acids, Monounsaturated; Female; Fluvastatin; Glutathione; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Imidazoles; Indoles; Male; Middle Aged; Nitric Oxide; Oxidation-Reduction; Oxidative Stress; Platelet Aggregation; Polyisoprenyl Phosphates; Prospective Studies; Resins, Synthetic; Treatment Outcome; Triglycerides; Tyrosine

2007
Comparison of sevelamer hydrochloride with colestimide, administered alone or in combination with calcium carbonate, in patients on hemodialysis.
    Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy, 2008, Volume: 12, Issue:2

    Topics: Adult; Aged; Calcium; Calcium Carbonate; Chelating Agents; Drug Therapy, Combination; Epichlorohydrin; Female; Humans; Hyperparathyroidism, Secondary; Hyperphosphatemia; Imidazoles; Japan; Kidney Failure, Chronic; Male; Middle Aged; Phosphorus; Polyamines; Prospective Studies; Renal Dialysis; Resins, Synthetic; Sevelamer

2008
Effects of rosuvastatin and colestimide on metabolic parameters and urinary monocyte chemoattractant protein-1 in type 2 diabetic patients with hyperlipidemia.
    Southern medical journal, 2009, Volume: 102, Issue:4

    Topics: C-Reactive Protein; Chemokine CCL2; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Dinoprost; Enzyme-Linked Immunosorbent Assay; Epichlorohydrin; Female; Fluorobenzenes; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Imidazoles; Male; Middle Aged; Oxidative Stress; Peptide Fragments; Prospective Studies; Pyrimidines; Resins, Synthetic; Retinol-Binding Proteins; Rosuvastatin Calcium; Sulfonamides

2009
Comparison of efficacy of pitavastatin and colestimide in Japanese patients with diabetes mellitus complicated by hyperlipidemia and metabolic syndrome.
    Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 2011, Volume: 119, Issue:9

    Topics: Adult; Aged; Albuminuria; Atherosclerosis; Biomarkers; C-Reactive Protein; Cholesterol, LDL; Diabetes Complications; Epichlorohydrin; Female; Glycated Hemoglobin; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperglycemia; Hyperlipidemias; Hypolipidemic Agents; Imidazoles; Insulin Resistance; Japan; Male; Metabolic Syndrome; Middle Aged; Obesity; Quinolines; Resins, Synthetic; Triglycerides; Weight Loss

2011
Efficacy and safety of coadministration of rosuvastatin, ezetimibe, and colestimide in heterozygous familial hypercholesterolemia.
    The American journal of cardiology, 2012, Feb-01, Volume: 109, Issue:3

    Topics: Aged; Aged, 80 and over; Anion Exchange Resins; Anticholesteremic Agents; Azetidines; Cholesterol, LDL; Dose-Response Relationship, Drug; Drug Therapy, Combination; Epichlorohydrin; Ezetimibe; Female; Fluorobenzenes; Follow-Up Studies; Heterozygote; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipoproteinemia Type II; Imidazoles; Male; Middle Aged; Prospective Studies; Pyrimidines; Resins, Synthetic; Rosuvastatin Calcium; Sulfonamides; Treatment Outcome

2012
Hypoglycemic effects of colestimide on type 2 diabetic patients with obesity.
    Endocrine journal, 2012, Volume: 59, Issue:3

    Topics: Blood Glucose; Body Weight; Diabetes Mellitus, Type 2; Epichlorohydrin; Female; Humans; Hypoglycemic Agents; Imidazoles; Insulin Resistance; Male; Middle Aged; Obesity; Pilot Projects; Resins, Synthetic; Treatment Outcome

2012
Changes in lipoprotein lipase and endothelial lipase mass in familial hypercholesterolemia during three-drug lipid-lowering combination therapy.
    Lipids in health and disease, 2016, Apr-02, Volume: 15

    Topics: Adult; Aged; Anticholesteremic Agents; Drug Therapy, Combination; Epichlorohydrin; Ezetimibe; Female; Humans; Hyperlipoproteinemia Type II; Imidazoles; Lipase; Lipoprotein Lipase; Male; Middle Aged; Receptors, LDL; Resins, Synthetic; Rosuvastatin Calcium

2016
Effect of colestimide on the concentrations of polychlorinated dibenzo-p-dioxins, polychlorinated dizenzofurans, and polychlorinated biphenyls in blood of Yusho patients.
    Environmental health : a global access science source, 2016, 06-04, Volume: 15, Issue:1

    Topics: Aged; Aged, 80 and over; Dibenzofurans, Polychlorinated; Environmental Pollutants; Epichlorohydrin; Female; Humans; Imidazoles; Male; Middle Aged; Polychlorinated Biphenyls; Polychlorinated Dibenzodioxins; Porphyrias; Resins, Synthetic

2016

Other Studies

26 other study(ies) available for epichlorohydrin and mci-196

ArticleYear
Studies on adsorption characteristics of bile acids and methotrexate to a new type of anion-exchange resin, colestimide.
    Chemical & pharmaceutical bulletin, 2000, Volume: 48, Issue:7

    Topics: Anion Exchange Resins; Antidotes; Bile Acids and Salts; Epichlorohydrin; Humans; Imidazoles; Intestinal Absorption; Methotrexate; Resins, Synthetic; Water

2000
Rapid improvement of icterus and pruritus by the oral administration of colestimide in two cases of drug-induced hepatitis.
    Internal medicine (Tokyo, Japan), 2001, Volume: 40, Issue:11

    Topics: Adult; Anion Exchange Resins; Antidotes; Chemical and Drug Induced Liver Injury; Cholestasis, Intrahepatic; Contraceptives, Oral, Combined; Epichlorohydrin; Ethinyl Estradiol-Norgestrel Combination; Female; Humans; Imidazoles; Male; Middle Aged; Pruritus; Resins, Synthetic; Treatment Outcome

2001
Effect of colestimide on absorption of unconjugated bile acids in the rat jejunum.
    Journal of gastroenterology and hepatology, 2002, Volume: 17, Issue:6

    Topics: Animals; Anion Exchange Resins; Bile Acids and Salts; Cholic Acid; Deoxycholic Acid; Epichlorohydrin; Imidazoles; Intestinal Absorption; Jejunum; Male; Rats; Rats, Sprague-Dawley; Resins, Synthetic; Time Factors

2002
Colestimide: the efficacy of a novel anion-exchange resin in cholestatic disorders.
    Journal of gastroenterology and hepatology, 2002, Volume: 17, Issue:11

    Topics: Anion Exchange Resins; Antipruritics; Bile Acids and Salts; Cholagogues and Choleretics; Cholestasis; Cholestyramine Resin; Cholic Acid; Epichlorohydrin; Humans; Imidazoles; Pruritus; Resins, Synthetic; Ursodeoxycholic Acid

2002
Inhibition of ileal bile acid absorption by colestimide.
    Journal of gastroenterology and hepatology, 2003, Volume: 18, Issue:5

    Topics: Animals; Anion Exchange Resins; Bile Acids and Salts; Epichlorohydrin; Ileum; Imidazoles; Intestinal Absorption; Male; Rats; Rats, Sprague-Dawley; Resins, Synthetic

2003
Early intervention with atorvastatin modulates TH1/TH2 imbalance in patients with acute coronary syndrome: from bedside to bench.
    Circulation, 2004, May-11, Volume: 109, Issue:18

    Topics: Acute Disease; Angina Pectoris; Angina, Unstable; Anion Exchange Resins; Anti-Inflammatory Agents, Non-Steroidal; Anticholesteremic Agents; Atorvastatin; CD4 Lymphocyte Count; Coronary Disease; Epichlorohydrin; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Imidazoles; Immunophenotyping; Male; Prospective Studies; Pyrroles; Resins, Synthetic; Th1 Cells; Th2 Cells

2004
Colestimide co-administered with atorvastatin attenuates the progression of vascular calcification in haemodialysis patients.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2004, Volume: 19, Issue:8

    Topics: Anion Exchange Resins; Anticholesteremic Agents; Atorvastatin; Blood Vessels; Calcinosis; Disease Progression; Drug Therapy, Combination; Epichlorohydrin; Heptanoic Acids; Humans; Imidazoles; Prospective Studies; Pyrroles; Renal Dialysis; Resins, Synthetic

2004
Pilot study to reduce dioxins in the human body.
    Internal medicine (Tokyo, Japan), 2004, Volume: 43, Issue:9

    Topics: Adult; Aged; Anion Exchange Resins; Anticholesteremic Agents; Body Burden; Dioxins; Epichlorohydrin; Female; Humans; Hyperlipoproteinemias; Imidazoles; Male; Middle Aged; Pesticide Residues; Pilot Projects; Resins, Synthetic

2004
Usefulness of preheparin lipoprotein lipase mass as a parameter for predicting the efficacy of colestimide.
    Journal of atherosclerosis and thrombosis, 2005, Volume: 12, Issue:4

    Topics: Anion Exchange Resins; Body Weight; Cholesterol; Epichlorohydrin; Female; Humans; Hyperlipidemias; Imidazoles; Lipoprotein Lipase; Male; Middle Aged; Resins, Synthetic; Treatment Outcome; Triglycerides

2005
Effect of oral colestimide on the elimination of high-dose methotrexate in patients with primary central nervous system lymphoma--case report.
    Neurologia medico-chirurgica, 2005, Volume: 45, Issue:12

    Topics: Administration, Oral; Adult; Antimetabolites, Antineoplastic; Central Nervous System Neoplasms; Epichlorohydrin; Humans; Imidazoles; Lymphoma; Male; Methotrexate; Middle Aged; Resins, Synthetic

2005
Colestimide reduces blood polychlorinated biphenyl (PCB) levels.
    Internal medicine (Tokyo, Japan), 2006, Volume: 45, Issue:5

    Topics: Aged; Anion Exchange Resins; Dioxins; Epichlorohydrin; Female; Humans; Imidazoles; Male; Middle Aged; Pilot Projects; Polychlorinated Biphenyls; Resins, Synthetic

2006
Prevention and treatment of obesity, insulin resistance, and diabetes by bile acid-binding resin.
    Diabetes, 2007, Volume: 56, Issue:1

    Topics: Adipose Tissue; Animals; Anticholesteremic Agents; Blood Glucose; Body Weight; Carrier Proteins; Cholestyramine Resin; Diabetes Mellitus, Type 2; Disease Models, Animal; Epichlorohydrin; Fasting; Fatty Liver; Humans; Hyperlipidemias; Imidazoles; Insulin Resistance; Membrane Glycoproteins; Mice; Obesity; Resins, Synthetic; Weight Gain

2007
Effects of colestimide on blood glucose-lowering activity and body weight in patients with type 2 diabetes and hypercholesterolemia.
    Journal of Nippon Medical School = Nippon Ika Daigaku zasshi, 2007, Volume: 74, Issue:1

    Topics: Anion Exchange Resins; Blood Glucose; Body Weight; Diabetes Mellitus, Type 2; Epichlorohydrin; Humans; Hypercholesterolemia; Imidazoles; Lipids; Resins, Synthetic

2007
Sterol regulatory element-binding protein-2- and liver X receptor-driven dual promoter regulation of hepatic ABC transporter A1 gene expression: mechanism underlying the unique response to cellular cholesterol status.
    The Journal of biological chemistry, 2007, Jul-20, Volume: 282, Issue:29

    Topics: Animals; ATP Binding Cassette Transporter 1; ATP-Binding Cassette Transporters; Base Sequence; Bile Acids and Salts; Cell Line, Tumor; Cholesterol; DNA-Binding Proteins; Epichlorohydrin; Gene Expression Regulation; Imidazoles; Liver; Liver X Receptors; Molecular Sequence Data; Orphan Nuclear Receptors; Pravastatin; Promoter Regions, Genetic; Rats; Receptors, Cytoplasmic and Nuclear; Resins, Synthetic; Sterol Regulatory Element Binding Protein 2

2007
Colestimide lowers plasma glucose levels and increases plasma glucagon-like PEPTIDE-1 (7-36) levels in patients with type 2 diabetes mellitus complicated by hypercholesterolemia.
    Journal of Nippon Medical School = Nippon Ika Daigaku zasshi, 2007, Volume: 74, Issue:5

    Topics: Anion Exchange Resins; Blood Glucose; Diabetes Mellitus, Type 2; Epichlorohydrin; Female; Glucagon-Like Peptide 1; Humans; Hypercholesterolemia; Imidazoles; Lipids; Male; Middle Aged; Resins, Synthetic

2007
[In-vitro study of the drug interactions between Miglitol, an alpha-glucosidase inhibitor, and adsorbents].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2007, Volume: 127, Issue:12

    Topics: 1-Deoxynojirimycin; Adsorption; Carbohydrates; Carbon; Cation Exchange Resins; Cholestyramine Resin; Drug Interactions; Enzyme Inhibitors; Epichlorohydrin; Glycoside Hydrolase Inhibitors; Hydrogen-Ion Concentration; Hypoglycemic Agents; Imidazoles; Imino Pyranoses; In Vitro Techniques; Polyamines; Polystyrenes; Resins, Synthetic; Sevelamer

2007
Successful treatment with colestimide for a bout of cholestasis in a Japanese patient with benign recurrent intrahepatic cholestasis caused by ATP8B1 mutation.
    Internal medicine (Tokyo, Japan), 2008, Volume: 47, Issue:7

    Topics: Adenosine Triphosphatases; Adult; Asian People; Cholestasis; Cholestasis, Intrahepatic; Epichlorohydrin; Female; Humans; Imidazoles; Mutation; Resins, Synthetic; Secondary Prevention; Treatment Outcome

2008
Lack of relationship between blood glucose-lowering activity of colestimide and serum cholecystokinin (CCK) concentrations in patients with type 2 diabetes.
    Journal of Nippon Medical School = Nippon Ika Daigaku zasshi, 2008, Volume: 75, Issue:2

    Topics: Aged; Anion Exchange Resins; Blood Glucose; Cholecystokinin; Diabetes Mellitus, Type 2; Epichlorohydrin; Female; Humans; Hypercholesterolemia; Imidazoles; Male; Resins, Synthetic

2008
Colestimide, an anion exchange resin agent, can decrease the number of LDL particles without affecting their size in patients with hyperlipidemia.
    Journal of cardiology, 2010, Volume: 55, Issue:1

    Topics: Anion Exchange Resins; Apolipoproteins B; Epichlorohydrin; Female; Humans; Hyperlipidemias; Imidazoles; Lipoproteins, LDL; Magnetic Resonance Spectroscopy; Male; Middle Aged; Particle Size; Resins, Synthetic

2010
[A case of type 2 diabetes mellitus associated with familial hypercholesterolemia confirming the improvement of blood glucose control by colestimide].
    Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics, 2009, Volume: 46, Issue:6

    Topics: Aged; Diabetes Mellitus, Type 2; Epichlorohydrin; Female; Humans; Hyperlipoproteinemia Type II; Imidazoles; Resins, Synthetic

2009
Glucose-lowering effect of colestimide is associated with baseline HbA1c in type 2 diabetic patients with hypercholesterolemia.
    Endocrine journal, 2011, Volume: 58, Issue:3

    Topics: Aged; Atorvastatin; Blood Glucose; Comorbidity; Diabetes Mellitus, Type 2; Epichlorohydrin; Female; Glycated Hemoglobin; Heptanoic Acids; Humans; Hypercholesterolemia; Hypoglycemic Agents; Imidazoles; Lipids; Male; Middle Aged; Multivariate Analysis; Pravastatin; Pyrroles; Quinolines; Resins, Synthetic; Retrospective Studies; Treatment Outcome

2011
Bile acid binding resin improves metabolic control through the induction of energy expenditure.
    PloS one, 2012, Volume: 7, Issue:8

    Topics: Animals; Bile Acids and Salts; Cholesterol; Cholestyramine Resin; Energy Metabolism; Epichlorohydrin; Glucose; Glucose Tolerance Test; Imidazoles; Insulin Resistance; Male; Metabolic Syndrome; Mice; Mice, Inbred C57BL; Mice, Transgenic; Models, Biological; Protein Binding; Receptors, G-Protein-Coupled; Resins, Synthetic; Signal Transduction

2012
What characteristics at baseline are associated with the glucose-lowering effect of colestimide in patients with type 2 diabetes and hypercholesterolemia according to response to treatment?
    Journal of Nippon Medical School = Nippon Ika Daigaku zasshi, 2013, Volume: 80, Issue:3

    Topics: Aged; Blood Glucose; Body Mass Index; Cholelithiasis; Diabetes Mellitus, Type 2; Epichlorohydrin; Female; Glycated Hemoglobin; Humans; Hypercholesterolemia; Hypoglycemic Agents; Imidazoles; Male; Middle Aged; Pilot Projects; Regression Analysis; Resins, Synthetic; Time Factors; Treatment Outcome; Triglycerides

2013
Colestimide improves glycemic control via hepatic glucose production in db/db mice.
    Endocrine journal, 2014, Volume: 61, Issue:5

    Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Eating; Epichlorohydrin; Glucose; Glucose Clamp Technique; Glucose Tolerance Test; Hypoglycemic Agents; Imidazoles; Insulin Resistance; Liver; Mice; Mice, Inbred C57BL; Resins, Synthetic

2014
Cholesterol-Lowering Effect of Calcium Alginate in Rats.
    Biological & pharmaceutical bulletin, 2016, Volume: 39, Issue:1

    Topics: Alginates; Animals; Cholesterol; Dietary Fats; Dose-Response Relationship, Drug; Epichlorohydrin; Glucuronic Acid; Hexuronic Acids; Hypercholesterolemia; Hypolipidemic Agents; Imidazoles; Lipid Metabolism; Male; Random Allocation; Rats; Rats, Wistar; Resins, Synthetic; Specific Pathogen-Free Organisms

2016
Intestinal Bile Acid Composition Modulates Prohormone Convertase 1/3 (PC1/3) Expression and Consequent GLP-1 Production in Male Mice.
    Endocrinology, 2016, Volume: 157, Issue:3

    Topics: Animals; Bile Acids and Salts; Blood Glucose; Blotting, Western; Diet, High-Fat; Epichlorohydrin; Fluorescent Antibody Technique; Gene Expression; Glucagon-Like Peptide 1; Imidazoles; Insulin; Intestinal Mucosa; Intestines; Male; Mice; Proprotein Convertase 1; Receptors, G-Protein-Coupled; Resins, Synthetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Weight Gain

2016