Page last updated: 2024-08-25

epicatechin and quercetin

epicatechin has been researched along with quercetin in 35 studies

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (11.43)18.2507
2000's10 (28.57)29.6817
2010's19 (54.29)24.3611
2020's2 (5.71)2.80

Authors

AuthorsStudies
Chu, SC; Hsieh, YS; Lin, JY1
Habtemariam, S1
Calomme, M; Cimanga, K; Cos, P; Hu, JP; Pieters, L; Van Poel, B; Vanden Berghe, D; Vlietinck, AJ; Ying, L1
Ash, K; Grohmann, K; Manthey, CL; Manthey, JA; Montanari, A1
Broedel, SE; Cihlar, RL; ElSohly, HN; Ferreira, D; Jacob, MR; Joshi, AS; Khan, IA; Khan, SI; Li, XC; Raulli, RE; Walker, LA; Zhang, Z1
Bais, HP; Kennan, AJ; Stermitz, FR; Vivanco, JM; Walker, TS1
Baggett, S; Cui, B; Hequet, V; Kennelly, EJ; Ma, C; Mori, S; Protiva, P; Weinstein, IB; Yang, H1
Backlund, A; Bohlin, L; Gottfries, J; Larsson, J1
Brun, R; Lack, G; Perozzo, R; Rüedi, P; Scapozza, L; Tasdemir, D1
Gradisar, H; Jerala, R; Plaper, A; Pristovsek, P1
Bruno, RD; Chopra, P; Clement, OO; Gediya, LK; Khandelwal, A; Maheshwari, N; Njar, VC; Purushottamachar, P; Vasaitis, TS1
Medić-Sarić, M; Rastija, V1
Chou, CJ; Frei, N; Grigorov, M; Lo Piparo, E; Scheib, H; Williamson, G1
Gestwicki, JE; Reinke, AA; Seh, HY1
Carver, JA; Duggan, PJ; Ecroyd, H; Liu, Y; Meyer, AG; Tranberg, CE1
Amić, D; Lucić, B1
Liu, Y; Nair, MG1
Goettert, M; Koch, P; Laufer, S; Merfort, I; Schattel, V1
Kogami, Y; Matsuda, H; Nakamura, S; Sugiyama, T; Ueno, T; Yoshikawa, M1
Cai, S; Chu, L; Gao, F; Ji, B; Jia, G; Liu, J; Liu, Y; Wang, A; Wei, Y; Wu, W; Xie, L; Zhang, D; Zhou, F1
Alankuş-Çalişkan, Ö; Bedir, E; Ekinci, D; Koz, Ö; Perrone, A; Piacente, S; Supuran, CT1
Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P1
Bisson, J; Cluzet, S; Corio-Costet, MF; Lambert, C; Mérillon, JM; Papastamoulis, Y; Richard, T; Waffo-Téguo, P1
Bazinet, L; Cao, S; Christensen, KA; Clardy, J; Cryan, LM; Habeshian, KA; Rogers, MS1
Burger, MC; Corrêa, CJ; da Silva, MF; de Sousa, LR; de Souza, DH; Fernandes, JB; Iemma, MR; Lima, MI; Nebo, L; Ramalho, SD; Vieira, PC1
Bijak, M; Krotkiewski, H; Nowak, P; Pawlaczyk, I; Ponczek, M; Saluk, J; Wachowicz, B; Ziewiecki, R1
Adfa, M; Efdi, M; Hayashi, M; Kakumu, A; Koketsu, M; Ninomiya, M; Tanaka, K1
Balemba, OB; Frank, O; Hofmann, T; Salger, M; Stark, TD; Wakamatsu, J1
Bicknell, KA; Farrimond, JA; Putnam, SE; Swioklo, S; Watson, KA; Williamson, EM1
Hou, Y; Li, N; Li, W; Li, X; Meng, D; Wang, W; Wang, Y; Zhang, H; Zhang, X; Zhou, D1
Oliveri, V1
Abe, H; Adachi, I; Horino, Y; Kesamaru, H; Nose, T; Suyama, K; Tomohara, K1
Albiñana, CB; Brynda, J; Fanfrlík, J; Flieger, M; Hodek, J; Karlukova, E; Konvalinka, J; Kožíšek, M; Machara, A; Majer, P; Radilová, K; Weber, J; Zima, V1
Du, YP; Ma, BP; Pang, X; Wang, M; Wang, SY; Zhang, J; Zhao, Y; Zheng, XH1
Alunda, JM; Baptista, C; Behrens, B; Bifeld, E; Borsari, C; Clos, J; Cordeiro-da-Silva, A; Corral, MJ; Costantino, L; Costi, MP; Dello Iacono, L; Di Pisa, F; Eick, J; Ellinger, B; Ferrari, S; Gribbon, P; Gul, S; Henrich, S; Jiménez-Antón, MD; Keminer, O; Kohler, M; Kuzikov, M; Landi, G; Luciani, R; Mangani, S; Pellati, F; Poehner, I; Pozzi, C; Reinshagen, J; Santarem, N; Tait, A; Tejera Nevado, P; Torrado, J; Trande, M; Wade, RC; Witt, G; Wolf, M1

Reviews

1 review(s) available for epicatechin and quercetin

ArticleYear
Toward the discovery and development of effective modulators of α-synuclein amyloid aggregation.
    European journal of medicinal chemistry, 2019, Apr-01, Volume: 167

    Topics: alpha-Synuclein; Amyloidogenic Proteins; Drug Discovery; Humans; Protein Aggregation, Pathological; Structure-Activity Relationship

2019

Other Studies

34 other study(ies) available for epicatechin and quercetin

ArticleYear
Inhibitory effects of flavonoids on Moloney murine leukemia virus reverse transcriptase activity.
    Journal of natural products, 1992, Volume: 55, Issue:2

    Topics: DNA Polymerase I; Flavonoids; Leukemia Virus, Murine; Reverse Transcriptase Inhibitors; Structure-Activity Relationship

1992
Flavonoids as inhibitors or enhancers of the cytotoxicity of tumor necrosis factor-alpha in L-929 tumor cells.
    Journal of natural products, 1997, Volume: 60, Issue:8

    Topics: Animals; Apoptosis; Drug Synergism; Flavonoids; Mice; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha

1997
Structure-activity relationship and classification of flavonoids as inhibitors of xanthine oxidase and superoxide scavengers.
    Journal of natural products, 1998, Volume: 61, Issue:1

    Topics: Enzyme Inhibitors; Flavonoids; Free Radical Scavengers; Structure-Activity Relationship; Xanthine Oxidase

1998
Polymethoxylated flavones derived from citrus suppress tumor necrosis factor-alpha expression by human monocytes.
    Journal of natural products, 1999, Volume: 62, Issue:3

    Topics: Citrus; Cyclic AMP; Flavonoids; Humans; In Vitro Techniques; Lipopolysaccharides; Monocytes; Phosphodiesterase Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Necrosis Factor-alpha

1999
Fatty acid synthase inhibitors from plants: isolation, structure elucidation, and SAR studies.
    Journal of natural products, 2002, Volume: 65, Issue:12

    Topics: Antifungal Agents; Candida albicans; Combretaceae; Cryptococcus neoformans; Enzyme Inhibitors; Fatty Acid Synthases; Inhibitory Concentration 50; Isoflavones; Melastomataceae; Molecular Structure; Moraceae; Paspalum; Plants, Medicinal; Saccharomyces cerevisiae; Structure-Activity Relationship; Tannins; Triterpenes

2002
Structure-dependent phytotoxicity of catechins and other flavonoids: flavonoid conversions by cell-free protein extracts of Centaurea maculosa (spotted knapweed) roots.
    Journal of agricultural and food chemistry, 2003, Feb-12, Volume: 51, Issue:4

    Topics: Catechin; Centaurea; Flavonoids; Flavonols; Kaempferols; Plant Extracts; Plant Proteins; Plant Roots; Plants; Quercetin; Structure-Activity Relationship

2003
New bioactive polyphenols from Theobroma grandiflorum ("cupuaçu").
    Journal of natural products, 2003, Volume: 66, Issue:11

    Topics: Antineoplastic Agents, Phytogenic; Antioxidants; Biphenyl Compounds; Catechin; Colonic Neoplasms; Drug Screening Assays, Antitumor; Flavonoids; French Guiana; Glycosides; Humans; Inhibitory Concentration 50; Malvaceae; Molecular Structure; Picrates; Seeds; Tumor Cells, Cultured

2003
Expanding the ChemGPS chemical space with natural products.
    Journal of natural products, 2005, Volume: 68, Issue:7

    Topics: Biological Products; Combinatorial Chemistry Techniques; Computer Graphics; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Drug Evaluation, Preclinical; Molecular Structure; Prostaglandin-Endoperoxide Synthases; Structure-Activity Relationship

2005
Inhibition of Plasmodium falciparum fatty acid biosynthesis: evaluation of FabG, FabZ, and FabI as drug targets for flavonoids.
    Journal of medicinal chemistry, 2006, Jun-01, Volume: 49, Issue:11

    Topics: 3-Oxoacyl-(Acyl-Carrier-Protein) Reductase; Alcohol Oxidoreductases; Animals; Antimalarials; Catechin; Cells, Cultured; Chloroquine; Drug Resistance; Enoyl-(Acyl-Carrier-Protein) Reductase (NADH); Fatty Acids; Flavones; Flavonoids; Humans; Hydro-Lyases; Kinetics; Luteolin; Phenols; Plasmodium falciparum; Polyphenols; Structure-Activity Relationship

2006
Green tea catechins inhibit bacterial DNA gyrase by interaction with its ATP binding site.
    Journal of medicinal chemistry, 2007, Jan-25, Volume: 50, Issue:2

    Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Anti-Bacterial Agents; Binding Sites; Catechin; DNA Gyrase; Escherichia coli; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Models, Molecular; Structure-Activity Relationship; Tea; Topoisomerase II Inhibitors

2007
First pharmacophore-based identification of androgen receptor down-regulating agents: discovery of potent anti-prostate cancer agents.
    Bioorganic & medicinal chemistry, 2007, May-15, Volume: 15, Issue:10

    Topics: Androgen Antagonists; Androgen Receptor Antagonists; Antineoplastic Agents; Blotting, Western; Catalysis; Cell Line, Tumor; Computational Biology; Databases, Factual; Dose-Response Relationship, Drug; Down-Regulation; Humans; Male; Models, Molecular; Neoplasm Proteins; Prostatic Neoplasms; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles

2007
QSAR study of antioxidant activity of wine polyphenols.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:1

    Topics: Antioxidants; Flavonoids; Lipid Peroxidation; Molecular Conformation; Phenols; Polyphenols; Quantitative Structure-Activity Relationship; Regression Analysis; Wine

2009
Flavonoids for controlling starch digestion: structural requirements for inhibiting human alpha-amylase.
    Journal of medicinal chemistry, 2008, Jun-26, Volume: 51, Issue:12

    Topics: alpha-Amylases; Catalytic Domain; Digestion; Flavones; Flavonols; Humans; Hydrogen Bonding; Ligands; Models, Molecular; Protein Conformation; Saliva; Starch; Structure-Activity Relationship

2008
A chemical screening approach reveals that indole fluorescence is quenched by pre-fibrillar but not fibrillar amyloid-beta.
    Bioorganic & medicinal chemistry letters, 2009, Sep-01, Volume: 19, Issue:17

    Topics: Amyloid beta-Peptides; Benzothiazoles; Coloring Agents; Congo Red; Fluorescent Dyes; Indoles; Spectrometry, Fluorescence; Thiazoles

2009
Carboxymethylated-kappa-casein: a convenient tool for the identification of polyphenolic inhibitors of amyloid fibril formation.
    Bioorganic & medicinal chemistry, 2010, Jan-01, Volume: 18, Issue:1

    Topics: Alzheimer Disease; Amyloid; Amyloid beta-Peptides; Animals; Caseins; Flavonoids; Humans; Methylation; Milk; Structure-Activity Relationship

2010
Reliability of bond dissociation enthalpy calculated by the PM6 method and experimental TEAC values in antiradical QSAR of flavonoids.
    Bioorganic & medicinal chemistry, 2010, Jan-01, Volume: 18, Issue:1

    Topics: Flavonoids; Free Radical Scavengers; Models, Biological; Quantitative Structure-Activity Relationship; Quantum Theory; Software; Thermodynamics

2010
An efficient and economical MTT assay for determining the antioxidant activity of plant natural product extracts and pure compounds.
    Journal of natural products, 2010, Jul-23, Volume: 73, Issue:7

    Topics: Antioxidants; Coloring Agents; Formazans; Free Radical Scavengers; Mitochondria; Molecular Structure; NADP; Oxidation-Reduction; Plant Extracts; Singlet Oxygen; Tetrazolium Salts; Thiazoles

2010
Biological evaluation and structural determinants of p38α mitogen-activated-protein kinase and c-Jun-N-terminal kinase 3 inhibition by flavonoids.
    Chembiochem : a European journal of chemical biology, 2010, Dec-10, Volume: 11, Issue:18

    Topics: Animals; Flavonoids; Humans; Mitogen-Activated Protein Kinase 10; Mitogen-Activated Protein Kinase 14; Models, Molecular; Protein Kinase Inhibitors; Structure-Activity Relationship

2010
Structural requirements of flavonoids for the adipogenesis of 3T3-L1 cells.
    Bioorganic & medicinal chemistry, 2011, May-01, Volume: 19, Issue:9

    Topics: 3T3-L1 Cells; Adipogenesis; Animals; CCAAT-Enhancer-Binding Protein-alpha; CCAAT-Enhancer-Binding Protein-beta; CCAAT-Enhancer-Binding Protein-delta; Deoxyglucose; Fatty Acid-Binding Proteins; Flavonoids; Glucose Transporter Type 4; Mice; PPAR gamma; Structure-Activity Relationship

2011
Comparative study on antioxidant capacity of flavonoids and their inhibitory effects on oleic acid-induced hepatic steatosis in vitro.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:9

    Topics: Antioxidants; Cell Line; Fatty Liver; Flavonoids; Humans; In Vitro Techniques; Oleic Acid; Reactive Oxygen Species; Triglycerides

2011
Analysis of saponins and phenolic compounds as inhibitors of α-carbonic anhydrase isoenzymes.
    Journal of enzyme inhibition and medicinal chemistry, 2013, Volume: 28, Issue:2

    Topics: Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Dose-Response Relationship, Drug; Humans; Molecular Structure; Phenols; Protein Isoforms; Saponins; Structure-Activity Relationship; Sulfonamides; Sulfonic Acids

2013
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
    Bioorganic & medicinal chemistry, 2012, Nov-15, Volume: 20, Issue:22

    Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship

2012
Phenolics and their antifungal role in grapevine wood decay: focus on the Botryosphaeriaceae family.
    Journal of agricultural and food chemistry, 2012, Dec-05, Volume: 60, Issue:48

    Topics: Antifungal Agents; Ascomycota; Benzofurans; Host-Pathogen Interactions; Inhibitory Concentration 50; Phenols; Plant Diseases; Plant Stems; Stilbenes; Vitis; Wine; Wood

2012
1,2,3,4,6-Penta-O-galloyl-β-D-glucopyranose inhibits angiogenesis via inhibition of capillary morphogenesis gene 2.
    Journal of medicinal chemistry, 2013, Mar-14, Volume: 56, Issue:5

    Topics: Angiogenesis Inhibitors; Animals; Cell Line, Tumor; Cell Proliferation; Endothelial Cells; Humans; Hydrolyzable Tannins; Mice; Neovascularization, Pathologic; Receptors, Peptide

2013
Isolation of arginase inhibitors from the bioactivity-guided fractionation of Byrsonima coccolobifolia leaves and stems.
    Journal of natural products, 2014, Feb-28, Volume: 77, Issue:2

    Topics: Arginase; Brazil; Flavonoids; Inhibitory Concentration 50; Leishmania; Malpighiaceae; Molecular Structure; Plant Leaves; Plant Stems; Structure-Activity Relationship

2014
Thrombin inhibitory activity of some polyphenolic compounds.
    Medicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents, 2014, Volume: 23

    Topics:

2014
Phytochemical analysis and antileukemic activity of polyphenolic constituents of Toona sinensis.
    Bioorganic & medicinal chemistry letters, 2014, Sep-01, Volume: 24, Issue:17

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; HL-60 Cells; Humans; Leukemia; Meliaceae; Molecular Conformation; Phytochemicals; Phytotherapy; Plant Extracts; Plant Leaves; Structure-Activity Relationship; Wood

2014
Antioxidative compounds from Garcinia buchananii stem bark.
    Journal of natural products, 2015, Feb-27, Volume: 78, Issue:2

    Topics: Antioxidants; Biflavonoids; Depsides; Flavanones; Garcinia; Hydrogen Peroxide; Lactones; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Plant Bark; Tanzania; Terpenes; Xanthones

2015
Defining Key Structural Determinants for the Pro-osteogenic Activity of Flavonoids.
    Journal of natural products, 2015, Nov-25, Volume: 78, Issue:11

    Topics: Cell Differentiation; Flavonoids; Humans; Mesenchymal Stem Cells; Molecular Structure; Osteogenesis; Signal Transduction; Structure-Activity Relationship

2015
Bioactive phenols as potential neuroinflammation inhibitors from the leaves of Xanthoceras sorbifolia Bunge.
    Bioorganic & medicinal chemistry letters, 2016, 10-15, Volume: 26, Issue:20

    Topics: Animals; Anti-Inflammatory Agents; Cell Line; Encephalitis; Magnetic Resonance Spectroscopy; Mice; Phenols; Plant Extracts; Plant Leaves; Sapindaceae; Spectrometry, Mass, Electrospray Ionization

2016
DMSO-Perturbing Assay for Identifying Promiscuous Enzyme Inhibitors.
    ACS medicinal chemistry letters, 2019, Jun-13, Volume: 10, Issue:6

    Topics:

2019
Unraveling the anti-influenza effect of flavonoids: Experimental validation of luteolin and its congeners as potent influenza endonuclease inhibitors.
    European journal of medicinal chemistry, 2020, Dec-15, Volume: 208

    Topics: Antiviral Agents; Crystallography, X-Ray; Drug Evaluation, Preclinical; Endonucleases; Enzyme Assays; Enzyme Inhibitors; Flavonoids; Influenza A virus; Microbial Sensitivity Tests; Molecular Structure; Protein Binding; Protein Domains; RNA-Dependent RNA Polymerase; Structure-Activity Relationship; Viral Proteins

2020
Phenolic compounds from the leaves of Crataegus pinnatifida Bge. var. major N.E.Br. And their lipid-lowering effects.
    Bioorganic & medicinal chemistry letters, 2021, 09-01, Volume: 47

    Topics: Cell Survival; Crataegus; Dose-Response Relationship, Drug; Hep G2 Cells; Humans; Molecular Structure; Phenols; Plant Leaves; Structure-Activity Relationship; Triglycerides

2021
Profiling of Flavonol Derivatives for the Development of Antitrypanosomatidic Drugs.
    Journal of medicinal chemistry, 2016, 08-25, Volume: 59, Issue:16

    Topics: Animals; Biological Products; Cell Line; Dose-Response Relationship, Drug; Flavonols; Humans; Macrophages; Mice; Mice, Inbred BALB C; Models, Molecular; Molecular Structure; Parasitic Sensitivity Tests; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei brucei

2016