Page last updated: 2024-08-25

epicatechin and epigallocatechin gallate

epicatechin has been researched along with epigallocatechin gallate in 27 studies

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's11 (40.74)29.6817
2010's14 (51.85)24.3611
2020's2 (7.41)2.80

Authors

AuthorsStudies
Hong, YS; Hwang, BY; Kim, HS; Lee, JH; Lee, JJ; Lee, KS; Ro, JS1
Grossman, P; Hudson, RA; Hupe, D; Hupe, L; Sherette, A; Tillekeratne, LM1
Backlund, A; Bohlin, L; Gottfries, J; Larsson, J1
Backleh-Sohrt, M; Ekici, P; Leupold, G; Parlar, H1
Brun, R; Lack, G; Perozzo, R; Rüedi, P; Scapozza, L; Tasdemir, D1
Gradisar, H; Jerala, R; Plaper, A; Pristovsek, P1
Acoca, S; Beauparlant, P; Bélec, L; Billot, X; Cluse, L; Goulet, D; Johnstone, RW; Marcellus, RC; Murthy Madiraju, SR; Nguyen, M; Purisima, E; Roulston, A; Serfass, L; Shore, GC; Viallet, J; Watson, M; Wiegmans, A1
Cho, D; Cho, SY; Ham, M; Kim, JB; Lee, TR; Park, J; Shin, DW; Shin, ES; Shin, JM1
Cabezas-Herrera, J; Chazarra, S; Otón, F; Rodríguez-López, JN; Sánchez-del-Campo, L; Tárraga, A1
Gestwicki, JE; Reinke, AA; Seh, HY1
Bisson, WH; Dashwood, RH; Larsen, CA1
Carver, JA; Duggan, PJ; Ecroyd, H; Liu, Y; Meyer, AG; Tranberg, CE1
Amić, D; Lucić, B1
Cho, SJ; Park, KD1
Fujiwara, K; Murakami, N; Tamura, S; Yoshihira, K1
Aihara, Y; Akagawa, M; Furuta, T; Ichikawa, T; Ishii, T; Kaku, M; Kan, T; Kusaka, K; Mori, T; Nakayama, T; Uekusa, Y; Wakimoto, T1
Cai, S; Chu, L; Gao, F; Ji, B; Jia, G; Liu, J; Liu, Y; Wang, A; Wei, Y; Wu, W; Xie, L; Zhang, D; Zhou, F1
Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P1
Bulic, B; Mandelkow, E; Pickhardt, M1
Ceballos, G; Moreno-Ulloa, A; Ramirez-Sanchez, I; Romero-Perez, D; Villarreal, F1
Al-Asri, J; Fazekas, E; Görick, C; Gyémánt, G; Lehoczki, G; Melzig, MF; Mortier, J; Perdih, A; Wolber, G1
Bicknell, KA; Farrimond, JA; Putnam, SE; Swioklo, S; Watson, KA; Williamson, EM1
Adachi, I; Ito, T; Kato, A; Onikata, S; Tomohara, K1
Arnhold, J; Flemmig, J; Gau, J; Prévost, M; Rodewald, S; Sarosi, MB; Van Antwerpen, P1
Abe, H; Adachi, I; Horino, Y; Kesamaru, H; Nose, T; Suyama, K; Tomohara, K1
Albiñana, CB; Brynda, J; Fanfrlík, J; Flieger, M; Hodek, J; Karlukova, E; Konvalinka, J; Kožíšek, M; Machara, A; Majer, P; Radilová, K; Weber, J; Zima, V1
Arora, S; Chaturvedi, A; Heuser, M; Joshi, G; Kumar, R; Patil, S1

Reviews

1 review(s) available for epicatechin and epigallocatechin gallate

ArticleYear
Progress and developments in tau aggregation inhibitors for Alzheimer disease.
    Journal of medicinal chemistry, 2013, Jun-13, Volume: 56, Issue:11

    Topics: Alzheimer Disease; Animals; Clinical Trials as Topic; Humans; Hydrogen Bonding; Models, Molecular; Protein Binding; Protein Conformation; Structure-Activity Relationship; tau Proteins

2013

Other Studies

26 other study(ies) available for epicatechin and epigallocatechin gallate

ArticleYear
Antioxidant benzoylated flavan-3-ol glycoside from Celastrus orbiculatus.
    Journal of natural products, 2001, Volume: 64, Issue:1

    Topics: Antioxidants; Bepridil; Biphenyl Compounds; Catechin; Flavonoids; Free Radical Scavengers; Free Radicals; Hydrolysis; Picrates; Plants, Medicinal

2001
Simplified catechin-gallate inhibitors of HIV-1 reverse transcriptase.
    Bioorganic & medicinal chemistry letters, 2001, Oct-22, Volume: 11, Issue:20

    Topics: Catechin; HIV Reverse Transcriptase; Mutation; Reverse Transcriptase Inhibitors; Structure-Activity Relationship

2001
Expanding the ChemGPS chemical space with natural products.
    Journal of natural products, 2005, Volume: 68, Issue:7

    Topics: Biological Products; Combinatorial Chemistry Techniques; Computer Graphics; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Drug Evaluation, Preclinical; Molecular Structure; Prostaglandin-Endoperoxide Synthases; Structure-Activity Relationship

2005
Efficiency of foam fractionation for the enrichment of nonpolar compounds from aqueous extracts of plant materials.
    Journal of natural products, 2005, Volume: 68, Issue:9

    Topics: Carotenoids; Chemical Fractionation; Chromatography, High Pressure Liquid; Citrus; Curcuma; Curcumin; Cyclohexenes; Daucus carota; Flavanones; Hesperidin; Molecular Structure; Plant Extracts; Tea; Terpenes; Water

2005
Inhibition of Plasmodium falciparum fatty acid biosynthesis: evaluation of FabG, FabZ, and FabI as drug targets for flavonoids.
    Journal of medicinal chemistry, 2006, Jun-01, Volume: 49, Issue:11

    Topics: 3-Oxoacyl-(Acyl-Carrier-Protein) Reductase; Alcohol Oxidoreductases; Animals; Antimalarials; Catechin; Cells, Cultured; Chloroquine; Drug Resistance; Enoyl-(Acyl-Carrier-Protein) Reductase (NADH); Fatty Acids; Flavones; Flavonoids; Humans; Hydro-Lyases; Kinetics; Luteolin; Phenols; Plasmodium falciparum; Polyphenols; Structure-Activity Relationship

2006
Green tea catechins inhibit bacterial DNA gyrase by interaction with its ATP binding site.
    Journal of medicinal chemistry, 2007, Jan-25, Volume: 50, Issue:2

    Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Anti-Bacterial Agents; Binding Sites; Catechin; DNA Gyrase; Escherichia coli; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Models, Molecular; Structure-Activity Relationship; Tea; Topoisomerase II Inhibitors

2007
Small molecule obatoclax (GX15-070) antagonizes MCL-1 and overcomes MCL-1-mediated resistance to apoptosis.
    Proceedings of the National Academy of Sciences of the United States of America, 2007, Dec-04, Volume: 104, Issue:49

    Topics: Animals; Antineoplastic Agents; Apoptosis; bcl-2 Homologous Antagonist-Killer Protein; Boronic Acids; Bortezomib; Cell Line, Tumor; Cysteine Proteinase Inhibitors; Drug Resistance, Neoplasm; Humans; Indoles; Melanoma; Mice; Mitochondria; Myeloid Cell Leukemia Sequence 1 Protein; Neoplasm Proteins; Proteasome Inhibitors; Proto-Oncogene Proteins c-bcl-2; Pyrazines; Pyrroles

2007
Catechin gallates are NADP+-competitive inhibitors of glucose-6-phosphate dehydrogenase and other enzymes that employ NADP+ as a coenzyme.
    Bioorganic & medicinal chemistry, 2008, Apr-01, Volume: 16, Issue:7

    Topics: 3T3-L1 Cells; Adipocytes; Animals; Catechin; Coenzymes; Glucosephosphate Dehydrogenase; Humans; Kinetics; Mice; Molecular Structure; NADP; Structure-Activity Relationship

2008
Synthesis and biological activity of a 3,4,5-trimethoxybenzoyl ester analogue of epicatechin-3-gallate.
    Journal of medicinal chemistry, 2008, Apr-10, Volume: 51, Issue:7

    Topics: Antioxidants; Catechin; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Screening Assays, Antitumor; Folic Acid; Folic Acid Antagonists; Gene Expression Profiling; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Models, Molecular; Molecular Structure; NADP; RNA, Messenger; Stereoisomerism; Structure-Activity Relationship; Tea; Tetrahydrofolate Dehydrogenase; Thymidylate Synthase; Time Factors

2008
A chemical screening approach reveals that indole fluorescence is quenched by pre-fibrillar but not fibrillar amyloid-beta.
    Bioorganic & medicinal chemistry letters, 2009, Sep-01, Volume: 19, Issue:17

    Topics: Amyloid beta-Peptides; Benzothiazoles; Coloring Agents; Congo Red; Fluorescent Dyes; Indoles; Spectrometry, Fluorescence; Thiazoles

2009
Tea catechins inhibit hepatocyte growth factor receptor (MET kinase) activity in human colon cancer cells: kinetic and molecular docking studies.
    Journal of medicinal chemistry, 2009, Nov-12, Volume: 52, Issue:21

    Topics: Antineoplastic Agents; Camellia sinensis; Catechin; Cell Line, Tumor; Colonic Neoplasms; Drug Screening Assays, Antitumor; Flavonoids; Gallic Acid; Humans; Kinetics; Models, Molecular; Phenols; Polyphenols; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-met; Receptors, Growth Factor; Structure-Activity Relationship

2009
Carboxymethylated-kappa-casein: a convenient tool for the identification of polyphenolic inhibitors of amyloid fibril formation.
    Bioorganic & medicinal chemistry, 2010, Jan-01, Volume: 18, Issue:1

    Topics: Alzheimer Disease; Amyloid; Amyloid beta-Peptides; Animals; Caseins; Flavonoids; Humans; Methylation; Milk; Structure-Activity Relationship

2010
Reliability of bond dissociation enthalpy calculated by the PM6 method and experimental TEAC values in antiradical QSAR of flavonoids.
    Bioorganic & medicinal chemistry, 2010, Jan-01, Volume: 18, Issue:1

    Topics: Flavonoids; Free Radical Scavengers; Models, Biological; Quantitative Structure-Activity Relationship; Quantum Theory; Software; Thermodynamics

2010
Synthesis and antimicrobial activities of 3-O-alkyl analogues of (+)-catechin: improvement of stability and proposed action mechanism.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Anti-Infective Agents; Bacteria; Camellia sinensis; Catechin; Drug Design; Drug Stability; Fungi; Humans; Hydrogen-Ion Concentration; Microbial Sensitivity Tests; Molecular Structure; Tea

2010
New inhibitors for expression of IgE receptor on human mast cell.
    Bioorganic & medicinal chemistry letters, 2010, Apr-01, Volume: 20, Issue:7

    Topics: Anthocyanins; Anti-Allergic Agents; Catechin; Cell Line; Flavones; Flavonoids; Gene Expression; Humans; Hypersensitivity; Mast Cells; Receptors, IgE

2010
Structural characteristics of green tea catechins for formation of protein carbonyl in human serum albumin.
    Bioorganic & medicinal chemistry, 2010, Jul-15, Volume: 18, Issue:14

    Topics: Catechin; Humans; Molecular Structure; Protein Carbonylation; Pyrogallol; Serum Albumin; Tea

2010
Comparative study on antioxidant capacity of flavonoids and their inhibitory effects on oleic acid-induced hepatic steatosis in vitro.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:9

    Topics: Antioxidants; Cell Line; Fatty Liver; Flavonoids; Humans; In Vitro Techniques; Oleic Acid; Reactive Oxygen Species; Triglycerides

2011
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
    Bioorganic & medicinal chemistry, 2012, Nov-15, Volume: 20, Issue:22

    Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship

2012
Cell membrane mediated (-)-epicatechin effects on upstream endothelial cell signaling: evidence for a surface receptor.
    Bioorganic & medicinal chemistry letters, 2014, Jun-15, Volume: 24, Issue:12

    Topics: Antioxidants; Catechin; Cell Membrane; Dextrans; Endothelial Cells; Humans; Molecular Structure; Nitric Oxide; Phosphorylation; Receptors, Cell Surface; Signal Transduction

2014
From carbohydrates to drug-like fragments: Rational development of novel α-amylase inhibitors.
    Bioorganic & medicinal chemistry, 2015, Oct-15, Volume: 23, Issue:20

    Topics: alpha-Amylases; Carbohydrates; Dose-Response Relationship, Drug; Drug Discovery; Enzyme Inhibitors; High-Throughput Screening Assays; Humans; Models, Molecular; Molecular Structure; Structure-Activity Relationship

2015
Defining Key Structural Determinants for the Pro-osteogenic Activity of Flavonoids.
    Journal of natural products, 2015, Nov-25, Volume: 78, Issue:11

    Topics: Cell Differentiation; Flavonoids; Humans; Mesenchymal Stem Cells; Molecular Structure; Osteogenesis; Signal Transduction; Structure-Activity Relationship

2015
Discovery of hyaluronidase inhibitors from natural products and their mechanistic characterization under DMSO-perturbed assay conditions.
    Bioorganic & medicinal chemistry letters, 2017, 04-01, Volume: 27, Issue:7

    Topics: Animals; Binding Sites; Catechin; Cattle; Dimethyl Sulfoxide; Drug Discovery; Enzyme Assays; Enzyme Inhibitors; Glycyrrhizic Acid; Hyaluronoglucosaminidase; Male; Octoxynol; Panax; Plant Extracts; Prunus domestica; Saponins

2017
Tannins and Tannin-Related Derivatives Enhance the (Pseudo-)Halogenating Activity of Lactoperoxidase.
    Journal of natural products, 2017, 05-26, Volume: 80, Issue:5

    Topics: Halogenation; Hydrogen Peroxide; Hydrolyzable Tannins; Kinetics; Lactoperoxidase; Molecular Structure; Nitrobenzoates; Oxidation-Reduction; Plant Extracts; Proanthocyanidins; Rhizome; Sulfhydryl Compounds; Tannins; Thiocyanates

2017
DMSO-Perturbing Assay for Identifying Promiscuous Enzyme Inhibitors.
    ACS medicinal chemistry letters, 2019, Jun-13, Volume: 10, Issue:6

    Topics:

2019
Unraveling the anti-influenza effect of flavonoids: Experimental validation of luteolin and its congeners as potent influenza endonuclease inhibitors.
    European journal of medicinal chemistry, 2020, Dec-15, Volume: 208

    Topics: Antiviral Agents; Crystallography, X-Ray; Drug Evaluation, Preclinical; Endonucleases; Enzyme Assays; Enzyme Inhibitors; Flavonoids; Influenza A virus; Microbial Sensitivity Tests; Molecular Structure; Protein Binding; Protein Domains; RNA-Dependent RNA Polymerase; Structure-Activity Relationship; Viral Proteins

2020
A Perspective on Medicinal Chemistry Approaches for Targeting Pyruvate Kinase M2.
    Journal of medicinal chemistry, 2022, 01-27, Volume: 65, Issue:2

    Topics: Allosteric Regulation; Allosteric Site; Carrier Proteins; Chemistry, Pharmaceutical; Glycolysis; Humans; Membrane Proteins; Protein Kinase Inhibitors; Thyroid Hormone-Binding Proteins; Thyroid Hormones

2022