Page last updated: 2024-08-25

epicatechin and apigenin

epicatechin has been researched along with apigenin in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (15.00)18.2507
2000's6 (30.00)29.6817
2010's9 (45.00)24.3611
2020's2 (10.00)2.80

Authors

AuthorsStudies
Habtemariam, S1
Calomme, M; Cimanga, K; Cos, P; Hu, JP; Pieters, L; Van Poel, B; Vanden Berghe, D; Vlietinck, AJ; Ying, L1
Ash, K; Grohmann, K; Manthey, CL; Manthey, JA; Montanari, A1
Broedel, SE; Cihlar, RL; ElSohly, HN; Ferreira, D; Jacob, MR; Joshi, AS; Khan, IA; Khan, SI; Li, XC; Raulli, RE; Walker, LA; Zhang, Z1
Backlund, A; Bohlin, L; Gottfries, J; Larsson, J1
Brun, R; Lack, G; Perozzo, R; Rüedi, P; Scapozza, L; Tasdemir, D1
Katavic, PL; Lamb, K; Navarro, H; Prisinzano, TE1
Medić-Sarić, M; Rastija, V1
Gestwicki, JE; Reinke, AA; Seh, HY1
Amić, D; Lucić, B1
Fujiwara, K; Murakami, N; Tamura, S; Yoshihira, K1
Liu, Y; Nair, MG1
Goettert, M; Koch, P; Laufer, S; Merfort, I; Schattel, V1
Kogami, Y; Matsuda, H; Nakamura, S; Sugiyama, T; Ueno, T; Yoshikawa, M1
Cai, S; Chu, L; Gao, F; Ji, B; Jia, G; Liu, J; Liu, Y; Wang, A; Wei, Y; Wu, W; Xie, L; Zhang, D; Zhou, F1
Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P1
Al-Asri, J; Fazekas, E; Görick, C; Gyémánt, G; Lehoczki, G; Melzig, MF; Mortier, J; Perdih, A; Wolber, G1
Bicknell, KA; Farrimond, JA; Putnam, SE; Swioklo, S; Watson, KA; Williamson, EM1
Albiñana, CB; Brynda, J; Fanfrlík, J; Flieger, M; Hodek, J; Karlukova, E; Konvalinka, J; Kožíšek, M; Machara, A; Majer, P; Radilová, K; Weber, J; Zima, V1
Arora, S; Chaturvedi, A; Heuser, M; Joshi, G; Kumar, R; Patil, S1

Other Studies

20 other study(ies) available for epicatechin and apigenin

ArticleYear
Flavonoids as inhibitors or enhancers of the cytotoxicity of tumor necrosis factor-alpha in L-929 tumor cells.
    Journal of natural products, 1997, Volume: 60, Issue:8

    Topics: Animals; Apoptosis; Drug Synergism; Flavonoids; Mice; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha

1997
Structure-activity relationship and classification of flavonoids as inhibitors of xanthine oxidase and superoxide scavengers.
    Journal of natural products, 1998, Volume: 61, Issue:1

    Topics: Enzyme Inhibitors; Flavonoids; Free Radical Scavengers; Structure-Activity Relationship; Xanthine Oxidase

1998
Polymethoxylated flavones derived from citrus suppress tumor necrosis factor-alpha expression by human monocytes.
    Journal of natural products, 1999, Volume: 62, Issue:3

    Topics: Citrus; Cyclic AMP; Flavonoids; Humans; In Vitro Techniques; Lipopolysaccharides; Monocytes; Phosphodiesterase Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Necrosis Factor-alpha

1999
Fatty acid synthase inhibitors from plants: isolation, structure elucidation, and SAR studies.
    Journal of natural products, 2002, Volume: 65, Issue:12

    Topics: Antifungal Agents; Candida albicans; Combretaceae; Cryptococcus neoformans; Enzyme Inhibitors; Fatty Acid Synthases; Inhibitory Concentration 50; Isoflavones; Melastomataceae; Molecular Structure; Moraceae; Paspalum; Plants, Medicinal; Saccharomyces cerevisiae; Structure-Activity Relationship; Tannins; Triterpenes

2002
Expanding the ChemGPS chemical space with natural products.
    Journal of natural products, 2005, Volume: 68, Issue:7

    Topics: Biological Products; Combinatorial Chemistry Techniques; Computer Graphics; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Drug Evaluation, Preclinical; Molecular Structure; Prostaglandin-Endoperoxide Synthases; Structure-Activity Relationship

2005
Inhibition of Plasmodium falciparum fatty acid biosynthesis: evaluation of FabG, FabZ, and FabI as drug targets for flavonoids.
    Journal of medicinal chemistry, 2006, Jun-01, Volume: 49, Issue:11

    Topics: 3-Oxoacyl-(Acyl-Carrier-Protein) Reductase; Alcohol Oxidoreductases; Animals; Antimalarials; Catechin; Cells, Cultured; Chloroquine; Drug Resistance; Enoyl-(Acyl-Carrier-Protein) Reductase (NADH); Fatty Acids; Flavones; Flavonoids; Humans; Hydro-Lyases; Kinetics; Luteolin; Phenols; Plasmodium falciparum; Polyphenols; Structure-Activity Relationship

2006
Flavonoids as opioid receptor ligands: identification and preliminary structure-activity relationships.
    Journal of natural products, 2007, Volume: 70, Issue:8

    Topics: Flavonoids; Humans; Hypericum; Ligands; Narcotic Antagonists; Plants, Medicinal; Receptors, Opioid; Receptors, Opioid, kappa; Structure-Activity Relationship

2007
QSAR study of antioxidant activity of wine polyphenols.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:1

    Topics: Antioxidants; Flavonoids; Lipid Peroxidation; Molecular Conformation; Phenols; Polyphenols; Quantitative Structure-Activity Relationship; Regression Analysis; Wine

2009
A chemical screening approach reveals that indole fluorescence is quenched by pre-fibrillar but not fibrillar amyloid-beta.
    Bioorganic & medicinal chemistry letters, 2009, Sep-01, Volume: 19, Issue:17

    Topics: Amyloid beta-Peptides; Benzothiazoles; Coloring Agents; Congo Red; Fluorescent Dyes; Indoles; Spectrometry, Fluorescence; Thiazoles

2009
Reliability of bond dissociation enthalpy calculated by the PM6 method and experimental TEAC values in antiradical QSAR of flavonoids.
    Bioorganic & medicinal chemistry, 2010, Jan-01, Volume: 18, Issue:1

    Topics: Flavonoids; Free Radical Scavengers; Models, Biological; Quantitative Structure-Activity Relationship; Quantum Theory; Software; Thermodynamics

2010
New inhibitors for expression of IgE receptor on human mast cell.
    Bioorganic & medicinal chemistry letters, 2010, Apr-01, Volume: 20, Issue:7

    Topics: Anthocyanins; Anti-Allergic Agents; Catechin; Cell Line; Flavones; Flavonoids; Gene Expression; Humans; Hypersensitivity; Mast Cells; Receptors, IgE

2010
An efficient and economical MTT assay for determining the antioxidant activity of plant natural product extracts and pure compounds.
    Journal of natural products, 2010, Jul-23, Volume: 73, Issue:7

    Topics: Antioxidants; Coloring Agents; Formazans; Free Radical Scavengers; Mitochondria; Molecular Structure; NADP; Oxidation-Reduction; Plant Extracts; Singlet Oxygen; Tetrazolium Salts; Thiazoles

2010
Biological evaluation and structural determinants of p38α mitogen-activated-protein kinase and c-Jun-N-terminal kinase 3 inhibition by flavonoids.
    Chembiochem : a European journal of chemical biology, 2010, Dec-10, Volume: 11, Issue:18

    Topics: Animals; Flavonoids; Humans; Mitogen-Activated Protein Kinase 10; Mitogen-Activated Protein Kinase 14; Models, Molecular; Protein Kinase Inhibitors; Structure-Activity Relationship

2010
Structural requirements of flavonoids for the adipogenesis of 3T3-L1 cells.
    Bioorganic & medicinal chemistry, 2011, May-01, Volume: 19, Issue:9

    Topics: 3T3-L1 Cells; Adipogenesis; Animals; CCAAT-Enhancer-Binding Protein-alpha; CCAAT-Enhancer-Binding Protein-beta; CCAAT-Enhancer-Binding Protein-delta; Deoxyglucose; Fatty Acid-Binding Proteins; Flavonoids; Glucose Transporter Type 4; Mice; PPAR gamma; Structure-Activity Relationship

2011
Comparative study on antioxidant capacity of flavonoids and their inhibitory effects on oleic acid-induced hepatic steatosis in vitro.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:9

    Topics: Antioxidants; Cell Line; Fatty Liver; Flavonoids; Humans; In Vitro Techniques; Oleic Acid; Reactive Oxygen Species; Triglycerides

2011
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
    Bioorganic & medicinal chemistry, 2012, Nov-15, Volume: 20, Issue:22

    Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship

2012
From carbohydrates to drug-like fragments: Rational development of novel α-amylase inhibitors.
    Bioorganic & medicinal chemistry, 2015, Oct-15, Volume: 23, Issue:20

    Topics: alpha-Amylases; Carbohydrates; Dose-Response Relationship, Drug; Drug Discovery; Enzyme Inhibitors; High-Throughput Screening Assays; Humans; Models, Molecular; Molecular Structure; Structure-Activity Relationship

2015
Defining Key Structural Determinants for the Pro-osteogenic Activity of Flavonoids.
    Journal of natural products, 2015, Nov-25, Volume: 78, Issue:11

    Topics: Cell Differentiation; Flavonoids; Humans; Mesenchymal Stem Cells; Molecular Structure; Osteogenesis; Signal Transduction; Structure-Activity Relationship

2015
Unraveling the anti-influenza effect of flavonoids: Experimental validation of luteolin and its congeners as potent influenza endonuclease inhibitors.
    European journal of medicinal chemistry, 2020, Dec-15, Volume: 208

    Topics: Antiviral Agents; Crystallography, X-Ray; Drug Evaluation, Preclinical; Endonucleases; Enzyme Assays; Enzyme Inhibitors; Flavonoids; Influenza A virus; Microbial Sensitivity Tests; Molecular Structure; Protein Binding; Protein Domains; RNA-Dependent RNA Polymerase; Structure-Activity Relationship; Viral Proteins

2020
A Perspective on Medicinal Chemistry Approaches for Targeting Pyruvate Kinase M2.
    Journal of medicinal chemistry, 2022, 01-27, Volume: 65, Issue:2

    Topics: Allosteric Regulation; Allosteric Site; Carrier Proteins; Chemistry, Pharmaceutical; Glycolysis; Humans; Membrane Proteins; Protein Kinase Inhibitors; Thyroid Hormone-Binding Proteins; Thyroid Hormones

2022