epibatidine and a 85380

epibatidine has been researched along with a 85380 in 28 studies

Research

Studies (28)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	7 (25.00)	18.2507
2000's	19 (67.86)	29.6817
2010's	2 (7.14)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Dannals, RF; Gündisch, D; Horti, AG; Kimes, AS; Koren, AO; London, ED; Mukhin, AG	1
Arneric, SP; Bannon, AW; Curzon, P; Decker, MW; Nikkel, AL	1
Bottlaender, M; Coulon, C; Crouzel, C; Dollé, F; Fuseau, C; Guenther, I; Hinnen, F; Ottaviani, M; Valette, H	1
Decker, MW; Meyer, MD; Rueter, LE	1
Collins, AC; Jimenez, M; Marks, MJ; McIntosh, JM; Whiteaker, P	1
Khan, IM; Stanislaus, S; Taylor, P; Yaksh, TL; Zhang, L	1
Långström, B; Nordberg, A; Sihver, W	1
Beaudet, AL; Collins, AC; Marks, MJ; McIntosh, JM; Paylor, R; Peterson, CG; Whiteaker, P; Xu, W	1
Dávila-García, MI; Kellar, KJ; Musachio, JL; Nguyen, HN; Perry, DC; Xiao, Y	1
Ascarrunz, VS; Avila, AM; Dávila-García, MI; Kellar, KJ; Xiao, Y	1
Fan, H; Lai, A; McIntosh, JM; Quik, M; Sum, J	1
Collins, AC; Grady, SR; Marks, MJ; McIntosh, JM; Salminen, O; Whiteaker, P	1
Bisson, WH; Mu, L; Scapozza, L; Schubiger, PA; Westera, G	1
Kellar, KJ; Turner, JR	1
Badyuk, M; Daly, JW; Kellar, KJ; Ohtani, M; Oka, T; Xiao, Y	1
Bordia, T; Fan, H; Langston, JW; McIntosh, JM; Parameswaran, N; Quik, M	1
Bottlaender, M; Coulon, C; Dollé, F; Hinnen, F; Ottaviani, M; Roger, G; Saba, W; Syrota, A; Valette, H	1
Fan, H; Kulak, JM; Schneider, JS	1
Boulter, J; Brennan, RJ; Brown, RW; Collins, AC; Lindstrom, JM; Whiteaker, P; Wilking, JA	1
Blanton, MP; Duddempudi, PK; Hamouda, AK; Jin, X; Pandhare, A; Sanghvi, M; Srivastava, S; Steinbach, JH	1
Fonnum, F; Heath, CJ; Mineur, YS; Picciotto, MR; Walaas, SI; Wigestrand, MB	1
Feng, CS; Liu, Y; Piao, MH; Qiu, JP; Wang, YS	1
Abreo, MA; Anderson, DJ; Arneric, SP; Donnelly-roberts, DL; Garvey, DS; Gunn, DE; Hettinger, AM; Holladay, MW; Lin, NH; Martin, YC; Pavlik, PA; Sullivan, JP; Wasicak, JT; Williams, M	1
Dart, MJ; Holladay, MW; Lynch, JK	1
Anderson, DJ; Arneric, SP; Bannon, AW; Briggs, CA; Buckley, MJ; Campbell, JE; Decker, MW; Donnelly-Roberts, DL; He, Y; Holladay, MW; Kim, DJ; Kuntzweiler, TA; Lin, NH; Piattoni-Kaplan, M; Ryther, KB; Wasicak, JT; Williams, M	1
Bottlaender, M; Coulon, C; Crouzel, C; Dolci, L; Doll, F; Fuseau, C; Guenther, I; Hinnen, F; Valette, H; Vaufrey, F	1
Baydyuk, M; Davis, HE; Kellar, KJ; Wang, HP; Xiao, Y	1
Frølund, B; Jensen, AA; Krogsgaard-Larsen, P; Liljefors, T	1

Reviews

3 review(s) available for epibatidine and a 85380

Article	Year
Ligands for in vivo imaging of nicotinic receptor subtypes in Alzheimer brain. Acta neurologica Scandinavica. Supplementum, 2000, Volume: 176 Topics: Alzheimer Disease; Animals; Azetidines; Blood-Brain Barrier; Bridged Bicyclo Compounds, Heterocyclic; Cholinergic Agents; Humans; Ligands; Primates; Pyridines; Rats; Receptors, Nicotinic; Tomography, Emission-Computed	2000
Neuronal nicotinic acetylcholine receptors as targets for drug discovery. Journal of medicinal chemistry, 1997, Dec-19, Volume: 40, Issue:26 Topics: Acetylcholine; Animals; Binding Sites; Dopamine; Drug Design; Humans; Molecular Structure; Nervous System; Neurons; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Receptors, Nicotinic; Structure-Activity Relationship	1997
Neuronal nicotinic acetylcholine receptors: structural revelations, target identifications, and therapeutic inspirations. Journal of medicinal chemistry, 2005, Jul-28, Volume: 48, Issue:15 Topics: Allosteric Regulation; Amino Acid Sequence; Animals; Humans; Ligands; Mice; Mice, Knockout; Models, Molecular; Molecular Sequence Data; Nicotinic Agonists; Nicotinic Antagonists; Protein Conformation; Protein Subunits; Receptors, Nicotinic	2005

Other Studies

25 other study(ies) available for epibatidine and a 85380

Article	Year
2-, 5-, and 6-Halo-3-(2(S)-azetidinylmethoxy)pyridines: synthesis, affinity for nicotinic acetylcholine receptors, and molecular modeling. Journal of medicinal chemistry, 1998, Sep-10, Volume: 41, Issue:19 Topics: Animals; Azetidines; Binding, Competitive; Bridged Bicyclo Compounds, Heterocyclic; Ligands; Male; Models, Molecular; Nicotinic Agonists; Prosencephalon; Pyridines; Rats; Rats, Inbred F344; Receptors, Nicotinic; Structure-Activity Relationship	1998
Differences between the antinociceptive effects of the cholinergic channel activators A-85380 and (+/-)-epibatidine in rats. The Journal of pharmacology and experimental therapeutics, 1998, Volume: 287, Issue:3 Topics: Analgesics, Non-Narcotic; Anesthetics, Local; Animals; Azetidines; Bridged Bicyclo Compounds, Heterocyclic; Chlorisondamine; Dose-Response Relationship, Drug; Injections, Intraventricular; Lidocaine; Male; Mecamylamine; Nicotinic Agonists; Nicotinic Antagonists; Pain Measurement; Pyridines; Raphe Nuclei; Rats; Rats, Sprague-Dawley	1998
Characterization of the nicotinic ligand 2-[18F]fluoro-3-[2(S)-2-azetidinylmethoxy]pyridine in vivo. Life sciences, 1999, Volume: 64, Issue:5 Topics: Alkaloids; Animals; Azetidines; Azocines; Binding, Competitive; Brain; Bridged Bicyclo Compounds, Heterocyclic; Cerebellum; Fluorine Radioisotopes; Frontal Lobe; Kinetics; Ligands; Male; Mecamylamine; Nicotine; Nicotinic Agonists; Pyridines; Quinolizines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Thalamus; Tissue Distribution	1999
Spinal mechanisms underlying A-85380-induced effects on acute thermal pain. Brain research, 2000, Jul-28, Volume: 872, Issue:1-2 Topics: Adrenergic alpha-Agonists; Animals; Azetidines; Behavior, Animal; Bridged Bicyclo Compounds, Heterocyclic; Bungarotoxins; Clonidine; Dose-Response Relationship, Drug; Hot Temperature; Injections, Intraperitoneal; Injections, Spinal; Lumbosacral Region; Male; Mecamylamine; Microdialysis; Muscarinic Antagonists; Nicotinic Agonists; Nicotinic Antagonists; Norepinephrine; Pain; Pain Measurement; Pyridines; Rats; Rats, Sprague-Dawley; Reaction Time; Serotonin; Serotonin Antagonists; Spinal Cord	2000
Identification of a novel nicotinic binding site in mouse brain using [(125)I]-epibatidine. British journal of pharmacology, 2000, Volume: 131, Issue:4 Topics: Alkaloids; Animals; Autoradiography; Azetidines; Azocines; Binding Sites; Brain; Bridged Bicyclo Compounds, Heterocyclic; Iodine Radioisotopes; Male; Mice; Mice, Inbred C57BL; Nicotine; Nicotinic Agonists; Pyridines; Quinolizines; Receptors, Nicotinic	2000
A-85380 and epibatidine each interact with disparate spinal nicotinic receptor subtypes to achieve analgesia and nociception. The Journal of pharmacology and experimental therapeutics, 2001, Volume: 297, Issue:1 Topics: Analgesics, Non-Narcotic; Animals; Azetidines; Bridged Bicyclo Compounds, Heterocyclic; Dose-Response Relationship, Drug; Injections, Spinal; Male; Nicotinic Agonists; Nicotinic Antagonists; Phentolamine; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic	2001
Involvement of the alpha3 subunit in central nicotinic binding populations. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2002, Apr-01, Volume: 22, Issue:7 Topics: Animals; Autoradiography; Azetidines; Binding Sites; Binding, Competitive; Brain; Bridged Bicyclo Compounds, Heterocyclic; Conotoxins; Genotype; Habenula; Ligands; Mesencephalon; Mice; Mice, Knockout; Nicotinic Antagonists; Protein Binding; Protein Subunits; Pyridines; Receptors, Nicotinic; Tissue Distribution	2002
Measuring nicotinic receptors with characteristics of alpha4beta2, alpha3beta2 and alpha3beta4 subtypes in rat tissues by autoradiography. Journal of neurochemistry, 2002, Volume: 82, Issue:3 Topics: Alkaloids; Animals; Autoradiography; Azetidines; Azocines; Binding, Competitive; Brain; Bridged Bicyclo Compounds, Heterocyclic; Cell Line; Humans; Iodine Radioisotopes; Kidney; Ligands; Male; Nicotinic Antagonists; Organ Specificity; Pineal Gland; Protein Subunits; Pyridines; Quinolizines; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Spinal Cord; Superior Cervical Ganglion; Tissue Distribution	2002
Differential regulation of nicotinic acetylcholine receptors in PC12 cells by nicotine and nerve growth factor. Molecular pharmacology, 2003, Volume: 64, Issue:4 Topics: Animals; Azetidines; Binding Sites; Bridged Bicyclo Compounds, Heterocyclic; Cell Differentiation; Iodine Radioisotopes; Nerve Growth Factor; Nicotine; Nicotinic Agonists; PC12 Cells; Pyridines; Rats; Receptors, Nicotinic; Rubidium Radioisotopes; Tritium	2003
Selective recovery of striatal 125I-alpha-conotoxinmii nicotinic receptors after nigrostriatal damage in monkeys. Neuroscience, 2004, Volume: 127, Issue:2 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Azetidines; Bridged Bicyclo Compounds, Heterocyclic; Conotoxins; Corpus Striatum; Disease Models, Animal; Dopamine Plasma Membrane Transport Proteins; Female; Iodine Radioisotopes; Male; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Mice, Inbred C57BL; Nerve Tissue Proteins; Neural Pathways; Parkinsonian Disorders; Presynaptic Terminals; Pyridines; Receptors, Nicotinic; Recovery of Function; Saimiri; Substantia Nigra; Up-Regulation	2004
The subunit composition and pharmacology of alpha-Conotoxin MII-binding nicotinic acetylcholine receptors studied by a novel membrane-binding assay. Neuropharmacology, 2005, Volume: 48, Issue:5 Topics: Acetylcholine; Alkaloids; Animals; Azetidines; Azocines; Binding, Competitive; Brain; Bridged Bicyclo Compounds, Heterocyclic; Cell Membrane; Conotoxins; Dose-Response Relationship, Drug; Drug Interactions; Hydrogen-Ion Concentration; Iodine Isotopes; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Protein Binding; Protein Subunits; Pyridines; Quinolizines; Radioligand Assay; Receptors, Nicotinic; Time Factors	2005
Ligand selectivity for the acetylcholine binding site of the rat alpha4beta2 and alpha3beta4 nicotinic subtypes investigated by molecular docking. Journal of medicinal chemistry, 2005, Aug-11, Volume: 48, Issue:16 Topics: Acetylcholine; Animals; Azetidines; Binding Sites; Binding, Competitive; Brain; Bridged Bicyclo Compounds, Heterocyclic; Cell Line; Crystallography, X-Ray; Hydrogen Bonding; In Vitro Techniques; Isoxazoles; Ligands; Mice; Models, Molecular; Nerve Tissue Proteins; Oocytes; Pyridines; Pyrrolidines; Rats; Receptors, Nicotinic; Snails; Stereoisomerism; Thermodynamics; Xenopus	2005
Nicotinic cholinergic receptors in the rat cerebellum: multiple heteromeric subtypes. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2005, Oct-05, Volume: 25, Issue:40 Topics: Analysis of Variance; Animals; Azetidines; Bridged Bicyclo Compounds, Heterocyclic; Cerebellum; Competitive Bidding; Dose-Response Relationship, Drug; Immunoprecipitation; Iodine Isotopes; Nicotinic Agonists; Protein Binding; Protein Subunits; Pyridines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; RNA, Messenger; Tritium	2005
Mouse beta-TC6 insulinoma cells: high expression of functional alpha3beta4 nicotinic receptors mediating membrane potential, intracellular calcium, and insulin release. Molecular pharmacology, 2006, Volume: 69, Issue:3 Topics: Alkaloids; Animals; Azetidines; Azocines; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Calcium Signaling; Cell Membrane; Dimethylphenylpiperazinium Iodide; Insulin; Insulin-Secreting Cells; Insulinoma; Membrane Potentials; Mice; Nicotine; Nicotinic Agonists; Pyridines; Quinolizines; Receptors, Nicotinic; Tumor Cells, Cultured	2006
Partial recovery of striatal nicotinic receptors in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-lesioned monkeys with chronic oral nicotine. The Journal of pharmacology and experimental therapeutics, 2006, Volume: 319, Issue:1 Topics: Animals; Azetidines; Binding Sites; Bridged Bicyclo Compounds, Heterocyclic; Conotoxins; Corpus Striatum; Female; MPTP Poisoning; Nicotine; Parkinson Disease; Pyridines; Receptors, Nicotinic; Saimiri	2006
[18F]FPhEP and [18F]F2PhEP, two new epibatidine-based radioligands: evaluation for imaging nicotinic acetylcholine receptors in baboon brain. Synapse (New York, N.Y.), 2007, Volume: 61, Issue:9 Topics: Animals; Azetidines; Binding, Competitive; Brain; Brain Chemistry; Bridged Bicyclo Compounds, Heterocyclic; Dose-Response Relationship, Drug; Fluorine Radioisotopes; Image Interpretation, Computer-Assisted; Magnetic Resonance Imaging; Papio; Pyridines; Receptors, Nicotinic; Time Factors; Tomography, Emission-Computed	2007
Beta2* and beta4* nicotinic acetylcholine receptor expression changes with progressive parkinsonism in non-human primates. Neurobiology of disease, 2007, Volume: 27, Issue:3 Topics: Animals; Autoradiography; Azetidines; Brain; Bridged Bicyclo Compounds, Heterocyclic; Iodine Radioisotopes; Macaca; Nicotinic Agonists; Parkinsonian Disorders; Pyridines; Receptors, Nicotinic	2007
Pharmacological and immunochemical characterization of alpha2* nicotinic acetylcholine receptors (nAChRs) in mouse brain. Acta pharmacologica Sinica, 2009, Volume: 30, Issue:6 Topics: Animals; Autoradiography; Azetidines; Brain; Bridged Bicyclo Compounds, Heterocyclic; Gene Expression Regulation; Immunoprecipitation; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mutation; Nicotinic Agonists; Olfactory Bulb; Protein Subunits; Pyridines; Receptors, Nicotinic; RNA, Messenger	2009
Photoaffinity labeling the agonist binding domain of alpha4beta4 and alpha4beta2 neuronal nicotinic acetylcholine receptors with [(125)I]epibatidine and 5[(125)I]A-85380. Biochimica et biophysica acta, 2009, Volume: 1788, Issue:9 Topics: Amino Acid Sequence; Animals; Azetidines; Binding Sites; Bridged Bicyclo Compounds, Heterocyclic; Cells, Cultured; Humans; Iodine Radioisotopes; Molecular Sequence Data; Nicotinic Agonists; Oocytes; Photoaffinity Labels; Pyridines; Rats; Receptors, Nicotinic; Sequence Alignment; Xenopus	2009
Decreased α4β2 nicotinic receptor number in the absence of mRNA changes suggests post-transcriptional regulation in the spontaneously hypertensive rat model of ADHD. Journal of neurochemistry, 2011, Volume: 119, Issue:1 Topics: Aconitine; Animals; Attention Deficit Disorder with Hyperactivity; Azetidines; Brain Chemistry; Bridged Bicyclo Compounds, Heterocyclic; Bungarotoxins; In Vitro Techniques; Kinetics; Male; Membranes; Nicotinic Agonists; Nicotinic Antagonists; Protein Processing, Post-Translational; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Nicotinic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Thermodynamics	2011
Volatile anesthetic isoflurane inhibits LTP induction of hippocampal CA1 neurons through α4β2 nAChR subtype-mediated mechanisms. Annales francaises d'anesthesie et de reanimation, 2013, Volume: 32, Issue:10 Topics: Anesthetics, Inhalation; Animals; Azetidines; Bridged Bicyclo Compounds, Heterocyclic; CA1 Region, Hippocampal; Dihydro-beta-Erythroidine; Drug Interactions; Electric Stimulation; In Vitro Techniques; Isoflurane; Long-Term Potentiation; Mecamylamine; Muscarinic Agonists; Neural Pathways; Neurons; Nicotine; Nicotinic Agonists; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic	2013
Novel 3-Pyridyl ethers with subnanomolar affinity for central neuronal nicotinic acetylcholine receptors. Journal of medicinal chemistry, 1996, Feb-16, Volume: 39, Issue:4 Topics: Alkaloids; Animals; Azocines; Binding, Competitive; Brain; Cell Line; Cell Membrane; Ethers; Ganglia; Humans; Molecular Structure; Neurons; Nicotinic Agonists; Pyridines; Quinolizines; Radioligand Assay; Rats; Receptors, Nicotinic; Structure-Activity Relationship; Tritium	1996
Identification and initial structure-activity relationships of (R)-5-(2-azetidinylmethoxy)-2-chloropyridine (ABT-594), a potent, orally active, non-opiate analgesic agent acting via neuronal nicotinic acetylcholine receptors. Journal of medicinal chemistry, 1998, Feb-12, Volume: 41, Issue:4 Topics: Administration, Oral; Analgesics, Non-Narcotic; Animals; Azetidines; Diastole; Female; Humans; Injections, Intraperitoneal; Kinetics; Mice; Molecular Structure; Muscle Contraction; Neuroblastoma; Neurons; Nicotinic Agonists; Oocytes; Pain; Pain Measurement; Pyridines; Rats; Receptors, Nicotinic; Recombinant Proteins; Stereoisomerism; Structure-Activity Relationship; Tumor Cells, Cultured; Xenopus	1998
Synthesis and nicotinic acetylcholine receptor in vivo binding properties of 2-fluoro-3-[2(S)-2-azetidinylmethoxy]pyridine: a new positron emission tomography ligand for nicotinic receptors. Journal of medicinal chemistry, 1999, Jun-17, Volume: 42, Issue:12 Topics: Animals; Azetidines; Brain; Fluorine Radioisotopes; Humans; Ligands; Male; Papio; Pyridines; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Tissue Distribution; Tomography, Emission-Computed	1999
Pharmacology of the agonist binding sites of rat neuronal nicotinic receptor subtypes expressed in HEK 293 cells. Bioorganic & medicinal chemistry letters, 2004, Apr-19, Volume: 14, Issue:8 Topics: Animals; Binding Sites; Binding, Competitive; Cell Line; Gene Expression; Humans; Neurons; Nicotinic Agonists; Protein Subunits; Rats; Receptors, Nicotinic; Transfection	2004