Page last updated: 2024-08-21

ephedrine and dextromethorphan

ephedrine has been researched along with dextromethorphan in 36 studies

Research

Studies (36)

TimeframeStudies, this research(%)All Research%
pre-199013 (36.11)18.7374
1990's6 (16.67)18.2507
2000's14 (38.89)29.6817
2010's3 (8.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Matts, SG1
Thackray, P1
Chao, MK; Fusari, SA; Holcomb, IJ1
Barnhart, JW; Massad, EN1
Gadomski, A; Horton, L1
Board, AW; Magurno, JA1
Beresford, TP; Coleman, JH; Hall, RC; Nasdahl, CS; Stickney, SK1
Bryant, B; Cartwright, GW; Myer, P1
Foust, RT; Jeffers, LJ; Reddy, KR; Schiff, ER1
Julian, TN; Murtha, JL; Radebaugh, GW1
Lewis, ET1
Fleckenstein, JL1
Borodkin, S; Sundberg, DP1
Weippl, G1
Brown, TM; Finkelstein, JA; Magoon, MR; Mareth, TR; Skop, BP1
Hanzlick, R1
Baird, TJ; Briscoe, RJ; Carl, KL; Gauvin, DV; Holloway, FA; Sannerud, CA; Vallett, M; Vanecek, SA1
Cottingham, EM; Keck, PE; Soutullo, CA1
Stewart, JT; Wilcox, ML1
Antal, EJ; Batts, DH; Hendershot, PE; Hopkins, NK; Welshman, IR1
Díaz, JE; Nairn, SJ1
Jacob, JE; Sage, JI; Wagner, ML1
Cutchavaree, A; Kerekhanjananarong, V; Saengpanich, S; Supiyaphun, P1
VAN DONGEN, K1
Boland, DM; Hearn, WL; Lew, EO; Rein, J1
Chen, X; Chen, Y; Dong, Y; Hu, Z1
Ali, MS; Ghori, M; Khatri, AR; Rafiuddin, S1
Baldauf, S1
Chmara, ES; Collins, GL; Mundy, LA; Wingert, WE1
Chen, H; Chen, X; Liu, L; Liu, X1
Hasemann, P; Preu, L; ter Balk, M; Wätzig, H1
Goodale, M; Grender, JM; Hull, JD; Jerdack, GR; Mizoguchi, H; Tyler, BA; Wilson, A1
Essam, HM; Yehia, AM1

Reviews

3 review(s) available for ephedrine and dextromethorphan

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Psychiatric reactions produced by respiratory drugs.
    Psychosomatics, 1985, Volume: 26, Issue:7

    Topics: Adolescent; Adult; Albuterol; Bronchodilator Agents; Calcium Channel Blockers; Child; Cromolyn Sodium; Dextromethorphan; Ephedrine; Expectorants; Humans; Iodides; Mental Disorders; Nasal Decongestants; Parasympatholytics; Phenylpropanolamine; Psychoses, Substance-Induced; Theophylline

1985
Safety of selegiline with cold medications.
    The Annals of pharmacotherapy, 2003, Volume: 37, Issue:3

    Topics: Antiparkinson Agents; Antitussive Agents; Clinical Trials as Topic; Dextromethorphan; Drug Interactions; Ephedrine; Humans; Nasal Decongestants; Nonprescription Drugs; Selegiline

2003

Trials

6 trial(s) available for ephedrine and dextromethorphan

ArticleYear
A trial of Lotussin and linctus diphenhydramine in patients wth an irritant cough.
    The Journal of international medical research, 1977, Volume: 5, Issue:6

    Topics: Ammonium Chloride; Antitussive Agents; Chloroform; Citrates; Clinical Trials as Topic; Cough; Dextromethorphan; Diphenhydramine; Drug Combinations; Drug Evaluation; Ephedrine; Guaifenesin; Humans; Menthol

1977
A double-blind, crossover controlled evaluation of a syrup for the night-time relief of the symptoms of the common cold, containing paracetamol, dextromethorphan hydrobromide, doxylamine succinate and ephedrine sulphate.
    The Journal of international medical research, 1978, Volume: 6, Issue:2

    Topics: Acetaminophen; Adolescent; Adult; Clinical Trials as Topic; Common Cold; Dextromethorphan; Double-Blind Method; Doxylamine; Drug Combinations; Drug Evaluation; Ephedrine; Female; Humans; Male; Middle Aged

1978
Therapeutic approaches to the common cold in children.
    Clinical therapeutics, 1984, Volume: 6, Issue:4

    Topics: Antitussive Agents; Child; Child, Preschool; Clinical Trials as Topic; Common Cold; Cyproheptadine; Dextromethorphan; Diphenhydramine; Double-Blind Method; Drug Combinations; Ephedrine; Expectorants; Histamine H1 Antagonists; Humans; Levorphanol; Pseudoephedrine

1984
Linezolid: pharmacokinetic and pharmacodynamic evaluation of coadministration with pseudoephedrine HCl, phenylpropanolamine HCl, and dextromethorpan HBr.
    Journal of clinical pharmacology, 2001, Volume: 41, Issue:5

    Topics: Acetamides; Adult; Area Under Curve; Blood Pressure; Body Temperature; Dextromethorphan; Dizziness; Double-Blind Method; Drug Interactions; Drug Therapy, Combination; Ephedrine; Female; Headache; Heart Rate; Humans; Linezolid; Male; Mental Processes; Middle Aged; Monoamine Oxidase Inhibitors; Nonprescription Drugs; Oxazolidinones; Phenylpropanolamine; Regression Analysis; Sympathomimetics

2001
Treatment of the common cold.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2003, Volume: 86 Suppl 2

    Topics: Acetaminophen; Adolescent; Adult; Common Cold; Dextromethorphan; Doxylamine; Drug Combinations; Ephedrine; Expectorants; Female; Humans; Male; Middle Aged; Nonprescription Drugs; Patient Satisfaction; Promethazine; Prospective Studies; Pseudoephedrine; Quality of Life; Triprolidine

2003
Efficacy of a single evening dose of syrup containing paracetamol, dextromethorphan hydrobromide, doxylamine succinate and ephedrine sulfate in subjects with multiple common cold symptoms.
    International journal of clinical pharmacology and therapeutics, 2007, Volume: 45, Issue:4

    Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Antitussive Agents; Bronchodilator Agents; Common Cold; Dextromethorphan; Double-Blind Method; Doxylamine; Drug Combinations; Ephedrine; Female; Histamine H1 Antagonists; Humans; Male; Middle Aged; Prospective Studies; Sleep Wake Disorders

2007

Other Studies

27 other study(ies) available for ephedrine and dextromethorphan

ArticleYear
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
    Bioorganic & medicinal chemistry, 2007, Nov-15, Volume: 15, Issue:22

    Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption

2007
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Ion-pair reversed-phase high-pressure liquid chromatography of cough-cold syrups I: pseudoephedrine hydrochloride, brompheniramine maleate, and dextromethorphan hydrobromide.
    Journal of pharmaceutical sciences, 1979, Volume: 68, Issue:11

    Topics: Brompheniramine; Chromatography, High Pressure Liquid; Dextromethorphan; Ephedrine; Levorphanol; Methods; Pyridines

1979
Determination of dextromethorphan in serum by gas chromatography.
    Journal of chromatography, 1979, Aug-21, Volume: 163, Issue:4

    Topics: Administration, Oral; Adult; Animals; Chromatography, Gas; Dextromethorphan; Dogs; Drug Combinations; Ephedrine; Guaifenesin; Humans; Injections, Intraperitoneal; Injections, Intravenous; Levorphanol; Male; Time Factors

1979
The need for rational therapeutics in the use of cough and cold medicine in infants.
    Pediatrics, 1992, Volume: 89, Issue:4 Pt 2

    Topics: Antitussive Agents; Common Cold; Cough; Dextromethorphan; Drug Combinations; Ephedrine; Female; Humans; Infant; Pseudoephedrine; Pyridines; Tremor; Vomiting

1992
MAOIs, OTC drugs, and hypertensive crisis.
    The Journal of clinical psychiatry, 1990, Volume: 51, Issue:5

    Topics: Dextromethorphan; Drug Interactions; Drug Therapy, Combination; Ephedrine; Humans; Hypertension; Monoamine Oxidase Inhibitors; Nonprescription Drugs; Patient Education as Topic; Phenylephrine; Product Labeling

1990
Overdose with a combination decongestant, antihistamine and antitussive syrup.
    Indiana medicine : the journal of the Indiana State Medical Association, 1985, Volume: 78, Issue:9

    Topics: Dextromethorphan; Drug Combinations; Ephedrine; Histamine H1 Antagonists; Humans; Infant; Levorphanol; Male; Pseudoephedrine; Pyridines

1985
Nyquil-associated liver injury.
    The American journal of gastroenterology, 1989, Volume: 84, Issue:4

    Topics: Acetaminophen; Adult; Alcoholism; Chemical and Drug Induced Liver Injury; Dextromethorphan; Doxylamine; Drug Combinations; Ephedrine; Female; Humans; Levorphanol; Liver; Male; Middle Aged; Necrosis; Nonprescription Drugs; Promethazine; Pseudoephedrine; Pyridines

1989
Simultaneous determination of pseudoephedrine hydrochloride, chlorpheniramine maleate, and dextromethorphan hydrobromide by second-derivative photodiode array spectroscopy.
    Journal of pharmaceutical sciences, 1988, Volume: 77, Issue:8

    Topics: Chlorpheniramine; Chromatography, High Pressure Liquid; Delayed-Action Preparations; Dextromethorphan; Ephedrine; Hypromellose Derivatives; Levorphanol; Methylcellulose; Spectrophotometry, Ultraviolet; Tablets

1988
No promethazine in Nyquil.
    The New England journal of medicine, 1986, Apr-03, Volume: 314, Issue:14

    Topics: Acetaminophen; Dextromethorphan; Doxylamine; Drug Combinations; Ephedrine; Levorphanol; Nonprescription Drugs; Promethazine; Pseudoephedrine; Pyridines

1986
Nyquil and acute hepatic necrosis.
    The New England journal of medicine, 1985, Jul-04, Volume: 313, Issue:1

    Topics: Acetaminophen; Adult; Alcoholism; Chemical and Drug Induced Liver Injury; Dextromethorphan; Doxylamine; Drug Combinations; Ephedrine; Humans; Hypnotics and Sedatives; Levorphanol; Male; Nonprescription Drugs; Promethazine; Pseudoephedrine; Pyridines

1985
Polycarboxylic acid ion-exchange resin adsorbates for taste coverage in chewable tablets.
    Journal of pharmaceutical sciences, 1971, Volume: 60, Issue:10

    Topics: Adsorption; Animals; Carboxylic Acids; Dextromethorphan; Drug Compounding; Ephedrine; Histamine H1 Antagonists; Humans; Intestinal Absorption; Ion Exchange Resins; Lethal Dose 50; Mice; Rats; Spectrum Analysis; Tablets; Taste; Time Factors; Ultraviolet Rays

1971
The serotonin syndrome associated with paroxetine, an over-the-counter cold remedy, and vascular disease.
    The American journal of emergency medicine, 1994, Volume: 12, Issue:6

    Topics: Acetaminophen; Acute Disease; Akathisia, Drug-Induced; Blood Platelets; Dextromethorphan; Diagnosis, Differential; Doxylamine; Drug Combinations; Drug Interactions; Drug Therapy, Combination; Endothelium, Vascular; Ephedrine; Humans; Hypertension; Male; Middle Aged; Myoclonus; Nonprescription Drugs; Paroxetine; Peripheral Vascular Diseases; Promethazine; Pseudoephedrine; Sweating; Syndrome

1994
National Association of Medical Examiners Pediatric Toxicology (PedTox) Registry Report 3. Case submission summary and data for acetaminophen, benzene, carboxyhemoglobin, dextromethorphan, ethanol, phenobarbital, and pseudoephedrine.
    The American journal of forensic medicine and pathology, 1995, Volume: 16, Issue:4

    Topics: Acetaminophen; Benzene; Carboxyhemoglobin; Child, Preschool; Coroners and Medical Examiners; Dextromethorphan; Drug-Related Side Effects and Adverse Reactions; Ephedrine; Ethanol; Female; Humans; Infant; Infant, Newborn; Male; Phenobarbital; Registries; Societies, Medical

1995
The stimulus properties of two common over-the-counter drug mixtures: dextromethorphan + ephedrine and dextromethorphan + diphenhydramine.
    Journal of psychopharmacology (Oxford, England), 1998, Volume: 12, Issue:1

    Topics: Adrenergic Agents; Animals; Antitussive Agents; Dextromethorphan; Diphenhydramine; Discrimination Learning; Dose-Response Relationship, Drug; Drug Combinations; Ephedrine; Hypnotics and Sedatives; Male; Nonprescription Drugs; Psychomotor Performance; Rats; Rats, Sprague-Dawley

1998
Psychosis associated with pseudoephedrine and dextromethorphan.
    Journal of the American Academy of Child and Adolescent Psychiatry, 1999, Volume: 38, Issue:12

    Topics: Adolescent; Antitussive Agents; Central Nervous System Stimulants; Child; Dextromethorphan; Ephedrine; Female; Humans; Psychoses, Substance-Induced

1999
HPLC determination of guaifenesin with selected medications on underivatized silica with an aqueous-organic mobile phase.
    Journal of pharmaceutical and biomedical analysis, 2000, Volume: 23, Issue:5

    Topics: Antitussive Agents; Bronchodilator Agents; Capsules; Chromatography, High Pressure Liquid; Codeine; Dextromethorphan; Drug Combinations; Ephedrine; Expectorants; Guaifenesin; Indicators and Reagents; Reference Standards; Reproducibility of Results; Silicon Dioxide; Solutions

2000
Cold-syrup induced movement disorder.
    Pediatric emergency care, 2001, Volume: 17, Issue:3

    Topics: Adrenergic Agents; Antitussive Agents; Child; Common Cold; Cough; Dextromethorphan; Drug Combinations; Drug-Related Side Effects and Adverse Reactions; Ephedrine; Histamine H1 Antagonists; Humans; Male; Movement Disorders; Pseudoephedrine; Pyridines

2001
The effect of narcotine, ticarda and romilar on coughs and on the movements of the cilia in the air passages.
    Acta physiologica et pharmacologica Neerlandica, 1956, Volume: 4, Issue:4

    Topics: Cilia; Cough; Dextromethorphan; Ephedrine; Ketones; Morphine Derivatives; Movement; Noscapine; Respiratory System

1956
Fatal cold medication intoxication in an infant.
    Journal of analytical toxicology, 2003, Volume: 27, Issue:7

    Topics: Brompheniramine; Chromatography, Gas; Common Cold; Dextromethorphan; Ephedrine; Fatal Outcome; Female; Humans; Infant; Liver; Nonprescription Drugs

2003
Separation and determination of pseudoephedrine, dextromethorphan, diphenhydramine and chlorpheniramine in cold medicines by nonaqueous capillary electrophoresis.
    Journal of pharmaceutical and biomedical analysis, 2005, Sep-01, Volume: 39, Issue:1-2

    Topics: Chlorpheniramine; Common Cold; Dextromethorphan; Diphenhydramine; Electrophoresis, Capillary; Ephedrine; Reproducibility of Results

2005
A new hydrophilic interaction liquid chromatographic (HILIC) procedure for the simultaneous determination of pseudoephedrine hydrochloride (PSH), diphenhydramine hydrochloride (DPH) and dextromethorphan hydrobromide (DXH) in cough-cold formulations.
    Journal of pharmaceutical and biomedical analysis, 2007, Jan-04, Volume: 43, Issue:1

    Topics: Acetates; Antitussive Agents; Buffers; Chemical Phenomena; Chemistry, Physical; Chromatography, High Pressure Liquid; Dextromethorphan; Diphenhydramine; Drug Combinations; Ephedrine; Histamine H1 Antagonists; Hydrogen-Ion Concentration; Indicators and Reagents; Nasal Decongestants; Pharmaceutical Solutions; Reference Standards; Reproducibility of Results; Solvents; Spectrophotometry, Ultraviolet

2007
Vanished behind the counter. Starting this week, you'll need help buying your claritin and nyquil.
    U.S. news & world report, 2006, Oct-02, Volume: 141, Issue:12

    Topics: Acetaminophen; Dextromethorphan; Doxylamine; Drug Combinations; Ephedrine; Humans; Legislation, Drug; Loratadine; Methamphetamine; Nasal Decongestants; Promethazine; Pseudoephedrine; United States

2006
Possible role of pseudoephedrine and other over-the-counter cold medications in the deaths of very young children.
    Journal of forensic sciences, 2007, Volume: 52, Issue:2

    Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Antitussive Agents; Brompheniramine; Bronchodilator Agents; Cause of Death; Central Nervous System Depressants; Child; Child, Preschool; Chlorpheniramine; Common Cold; Databases as Topic; Dextromethorphan; Doxylamine; Ephedrine; Ethanol; Female; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Histamine H1 Antagonists; Humans; Infant; Male; Nonprescription Drugs; Philadelphia; Pyridines

2007
Separation and determination of four active components in medicinal preparations by flow injection-capillary electrophoresis.
    Journal of pharmaceutical and biomedical analysis, 2007, Apr-11, Volume: 43, Issue:5

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Antitussive Agents; Bronchodilator Agents; Buffers; Chlorpheniramine; Common Cold; Dextromethorphan; Electrophoresis, Capillary; Ephedrine; Flow Injection Analysis; Histamine H1 Antagonists; Hydrogen-Ion Concentration; Maleates; Reproducibility of Results; Time Factors

2007
Separation of cold medicine ingredients using a precise MEKC method at elevated pH.
    Electrophoresis, 2007, Volume: 28, Issue:11

    Topics: Acetaminophen; Buffers; Chromatography, Micellar Electrokinetic Capillary; Common Cold; Dextromethorphan; Doxylamine; Drug Combinations; Ephedrine; Excipients; Hydrogen-Ion Concentration; Reproducibility of Results; Sodium Dodecyl Sulfate

2007
Development and validation of a generic high-performance liquid chromatography for the simultaneous separation and determination of six cough ingredients: Robustness study on core-shell particles.
    Journal of separation science, 2016, Volume: 39, Issue:17

    Topics: Acetaminophen; Antitussive Agents; Chromatography, High Pressure Liquid; Dextromethorphan; Doxylamine; Ephedrine; Guaifenesin; Humans; Phenylephrine

2016