enzastaurin has been researched along with prednisone in 4 studies
| Studies (enzastaurin) | Trials (enzastaurin) | Recent Studies (post-2010) (enzastaurin) | Studies (prednisone) | Trials (prednisone) | Recent Studies (post-2010) (prednisone) |
|---|---|---|---|---|---|
| 188 | 52 | 99 | 41,222 | 5,274 | 8,409 |
| Protein | Taxonomy | enzastaurin (IC50) | prednisone (IC50) |
|---|---|---|---|
| Glucocorticoid receptor | Homo sapiens (human) | 1.146 | |
| Glycine receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | 1.146 | |
| Glycine receptor subunit beta | Rattus norvegicus (Norway rat) | 1.146 | |
| Glycine receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | 1.146 | |
| Glycine receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | 1.146 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ogura, M | 1 |
| Arrowsmith, ER; Fayad, LE; Hainsworth, JD; Hamid, O; Hsi, ED; Lin, BK; McCleod, M; Shi, P | 1 |
| Crump, M; Di Rocco, A; Fayad, L; Habermann, T; Hagberg, H; Hahka-Kemppinen, M; Hsi, ED; Kahl, B; Lee, JJ; Leppä, S; Lin, B; Mackensen, A; Nguyen, T; Offner, F; Ogura, M; Pinter-Brown, L; Rifkin, R; Savage, KJ; Schmitz, N; Schnell, F; Shi, P; Smith, S; Thornton, D; Tobinai, K; Yeh, SP | 1 |
| Brody, J; Cao, J; Han, I; Heineman, T; Jing, H; Jivani, M; Lansigan, F; Li, L; Liu, Y; Lue, JK; Luo, W; Maly, J; Nowakowski, GS; Rizvi, S; Smith, SD; Song, Y; Sun, J; Sun, X; Zhang, L; Zhang, Q; Zhu, J | 1 |
1 review(s) available for enzastaurin and prednisone
| Article | Year |
|---|---|
[Recent therapeutic progress in non-Hodgkin lymphoma: focusing on diffuse large B-cell lymphoma and follicular lymphoma].
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bendamustine Hydrochloride; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Gene Targeting; Hematopoietic Stem Cell Transplantation; Humans; Indoles; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Nitrogen Mustard Compounds; Prednisone; Prognosis; Purine Nucleosides; Pyrimidinones; Risk; Rituximab; Salvage Therapy; Sirolimus; Transplantation, Autologous; Vincristine | 2008 |
3 trial(s) available for enzastaurin and prednisone
| Article | Year |
|---|---|
A randomized, phase 2 study of R-CHOP plus enzastaurin vs R-CHOP in patients with intermediate- or high-risk diffuse large B-cell lymphoma.
Topics: Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Doxorubicin; Humans; Indoles; Lymphoma, Large B-Cell, Diffuse; Prednisone; Rituximab; Treatment Outcome; Vincristine | 2016 |
Randomized, Double-Blind, Phase III Trial of Enzastaurin Versus Placebo in Patients Achieving Remission After First-Line Therapy for High-Risk Diffuse Large B-Cell Lymphoma.
Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Double-Blind Method; Doxorubicin; Female; Humans; Indoles; Lymphoma, Large B-Cell, Diffuse; Male; Middle Aged; Prednisone; Protein Kinase C beta; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-bcl-2; Rituximab; Vincristine | 2016 |
ENGINE: a Phase III randomized placebo controlled study of enzastaurin/R-CHOP as frontline therapy in high-risk diffuse large B-cell lymphoma patients with the genomic biomarker DGM1.
Topics: Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Cyclophosphamide; Doxorubicin; Female; Genetic Association Studies; Genetic Predisposition to Disease; Humans; Indoles; Lymphoma, Large B-Cell, Diffuse; Male; Prednisone; Research Design; Rituximab; Vincristine | 2020 |