Page last updated: 2024-09-05

enrasentan and bosentan anhydrous

enrasentan has been researched along with bosentan anhydrous in 3 studies

Compound Research Comparison

Studies
(enrasentan)
Trials
(enrasentan)
Recent Studies (post-2010)
(enrasentan)
Studies
(bosentan anhydrous)
Trials
(bosentan anhydrous)
Recent Studies (post-2010) (bosentan anhydrous)
32201,836215630

Protein Interaction Comparison

ProteinTaxonomyenrasentan (IC50)bosentan anhydrous (IC50)
Endothelin receptor type BRattus norvegicus (Norway rat)0.095
Endothelin receptor type BHomo sapiens (human)0.3044
Endothelin-1 receptorHomo sapiens (human)0.2317
Endothelin-1 receptorRattus norvegicus (Norway rat)0.0047
Endothelin-1 receptorSus scrofa (pig)0.0075

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (33.33)18.2507
2000's2 (66.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dixon, DB; Jae, HS; Marsh, KC; Nguyen, B; Opgenorth, TJ; von Geldern, TW; Winn, M1
Abraham, WT; Lamba, S; Suresh, DP1
Minushkina, LO; Sidorenko, BA; ZateÄ­shchikov, DA1

Reviews

2 review(s) available for enrasentan and bosentan anhydrous

ArticleYear
New developments in heart failure: role of endothelin and the use of endothelin receptor antagonists.
    Journal of cardiac failure, 2000, Volume: 6, Issue:4

    Topics: Bosentan; Carboxylic Acids; Chronic Disease; Endothelin Receptor Antagonists; Endothelin-1; Heart Failure; Humans; Indans; Peptides, Cyclic; Prognosis; Pyridines; Pyrimidines; Receptors, Endothelin; Sulfonamides; Treatment Outcome

2000
[Endothelin receptor blockers--one more agent for the treatment of pulmonary hypertension].
    Kardiologiia, 2003, Volume: 43, Issue:9

    Topics: Antihypertensive Agents; Bosentan; Carboxylic Acids; Clinical Trials as Topic; Endothelin Receptor Antagonists; Endothelium, Vascular; Humans; Hypertension, Pulmonary; Indans; Pyridines; Sulfonamides; Tetrazoles; Vasodilator Agents

2003

Other Studies

1 other study(ies) available for enrasentan and bosentan anhydrous

ArticleYear
Pyrrolidine-3-carboxylic acids as endothelin antagonists. 2. Sulfonamide-based ETA/ETB mixed antagonists.
    Journal of medicinal chemistry, 1997, Sep-26, Volume: 40, Issue:20

    Topics: Administration, Oral; Animals; Atrasentan; Endothelin Receptor Antagonists; Half-Life; Male; Models, Chemical; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Receptor, Endothelin B; Receptors, Endothelin; Structure-Activity Relationship

1997