Page last updated: 2024-09-04

enoximone sulfoxide and enoximone

enoximone sulfoxide has been researched along with enoximone in 5 studies

Compound Research Comparison

Studies
(enoximone sulfoxide)
Trials
(enoximone sulfoxide)
Recent Studies (post-2010)
(enoximone sulfoxide)
Studies
(enoximone)
Trials
(enoximone)
Recent Studies (post-2010) (enoximone)
51051614636

Protein Interaction Comparison

ProteinTaxonomyenoximone sulfoxide (IC50)enoximone (IC50)
cAMP-specific 3',5'-cyclic phosphodiesterase 4AHomo sapiens (human)3.95
cAMP-specific 3',5'-cyclic phosphodiesterase 4BHomo sapiens (human)3.95
cAMP-specific 3',5'-cyclic phosphodiesterase 4CHomo sapiens (human)3.95
cAMP-specific 3',5'-cyclic phosphodiesterase 4DHomo sapiens (human)3.95
cGMP-inhibited 3',5'-cyclic phosphodiesterase BHomo sapiens (human)3.8
cGMP-inhibited 3',5'-cyclic phosphodiesterase AHomo sapiens (human)3.8
Endothelin-1 receptorSus scrofa (pig)2.9

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19903 (60.00)18.7374
1990's2 (40.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lissmann, H; Mitrovic, V; Neuzner, J; Pitschner, HF; Schlepper, M1
Kates, RE; Lebsack, C; Mead, RH; Ruder, MA; Smith, N; Winkle, RA1
Cooper, JD; Turnell, DC1
Boxenbaum, H; Hook, RH; Okerholm, RA; Thompson, GA1
Chan, KY; Lang, JF; Ohlweiler, DF; Okerholm, RA1

Trials

1 trial(s) available for enoximone sulfoxide and enoximone

ArticleYear
Disposition kinetics of orally administered enoximone in patients with moderate to severe heart failure.
    Journal of clinical pharmacology, 1991, Volume: 31, Issue:8

    Topics: Administration, Oral; Adult; Aged; Cardiotonic Agents; Enoximone; Female; Half-Life; Heart Failure; Humans; Imidazoles; Male; Metabolic Clearance Rate; Middle Aged; Time Factors

1991

Other Studies

4 other study(ies) available for enoximone sulfoxide and enoximone

ArticleYear
[Continuous enoximone infusion in patients with severe heart failure in dilated cardiomyopathy, hemodynamic, neurohumoral, chemical laboratory and clinical results].
    Zeitschrift fur Kardiologie, 1991, Volume: 80, Issue:6

    Topics: Aldosterone; Atrial Natriuretic Factor; Cardiomyopathy, Dilated; Cardiotonic Agents; Enoximone; Epinephrine; Heart Failure; Hemodynamics; Humans; Imidazoles; Infusions, Intravenous; Neurotransmitter Agents; Norepinephrine; Renin

1991
Automatic preparation of human serum samples for analysis of the drug enoximone and its sulphoxide metabolite using high-performance liquid chromatography.
    Journal of chromatography, 1986, Jul-11, Volume: 380, Issue:1

    Topics: Autoanalysis; Cardiotonic Agents; Chromatography, High Pressure Liquid; Enoximone; Humans; Imidazoles; Indicators and Reagents; Spectrophotometry, Ultraviolet

1986
Human serum and plasma protein binding of enoximone and its sulfoxide metabolite.
    Journal of pharmaceutical sciences, 1988, Volume: 77, Issue:12

    Topics: Animals; Blood Proteins; Cardiotonic Agents; Enoximone; Fatty Acids; Globulins; Hydrogen-Ion Concentration; Imidazoles; Male; Orosomucoid; Protein Binding; Rats; Rats, Inbred Strains; Temperature; Ultrafiltration

1988
Simultaneous analysis of a new cardiotonic agent, MDL 17,043, and its major sulfoxide metabolite in plasma by high-performance liquid chromatography.
    Journal of chromatography, 1984, Mar-09, Volume: 306

    Topics: Cardiotonic Agents; Chromatography, High Pressure Liquid; Drug Stability; Enoximone; Humans; Imidazoles; Mass Spectrometry; Oxidation-Reduction; Time Factors

1984