enkephalinamide-met, ala(2)- has been researched along with naloxone in 133 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 108 (81.20) | 18.7374 |
| 1990's | 19 (14.29) | 18.2507 |
| 2000's | 3 (2.26) | 29.6817 |
| 2010's | 3 (2.26) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cohen, GA; Doze, VA; Madison, DV | 1 |
| Asanuma, M; Hirata, H; Ogawa, N; Ogura, T; Ota, Z; Takayama, H | 1 |
| Koelbel, CB; Leduc, L; Mayer, EA; Snape, WJ; Vandeventer, G | 1 |
| Hernandez, LL; Powell, DA; Valentine, JD | 1 |
| Barnett, JA; Charles, R; Hughes, TK; Smith, EM; Stefano, GB | 1 |
| Chang, PL; Dixon, WR | 1 |
| Hughes, TK; Smith, EM; Stefano, GB | 1 |
| Bastidas, JA; Schmieg, RE; Yeo, CJ; Zinner, MJ | 1 |
| Dalsass, M; Siegel, A | 1 |
| Cacicedo, L; Sánchez Franco, F | 2 |
| Chorev, M; Friedman, ZY; Gilon, C; Laufer, R; Selinger, Z; Wormser, U | 1 |
| Laurent, S; Marsh, JD; Smith, TW | 1 |
| Inoki, R; Shibutani, T; Tsai, HY; Yonehara, N | 1 |
| Rand, MJ; Wong-Dusting, H | 2 |
| Leung, MK; Scharrer, B; Stefano, GB; Zhao, XH | 1 |
| Cripps, MM; Patchen-Moor, K | 1 |
| Makimura, M; Murakoshi, Y | 1 |
| Heyman, JS; Jiang, Q; Mosberg, HI; Porreca, F; Rothman, RB | 1 |
| Bueno, L; Liberge, M; Murillo-Lopez, D; Rivière, PJ | 1 |
| Dibona, GF; Jones, SY; Kapusta, DR; Kopp, UC | 1 |
| Gentle, MJ; Savory, CJ; Yeomans, MR | 1 |
| Baker, BI; Bird, DJ; Buckingham, JC; Mukherjee, S | 1 |
| Childers, SR | 1 |
| Henke, PG; Ray, A; Sullivan, RM | 1 |
| Deguchi, T; Yokoyama, E | 1 |
| Kalivas, PW; Miller, JS; Taylor, S | 1 |
| Inoki, R; Kudo, T; Ohkubo, T; Shibata, M; Takahashi, H | 1 |
| Akita, K; Hatanaka, H; Maruyama, M; Sugino, H | 1 |
| Morrison, S; Reis, DJ; Sapru, HN; Willette, RN | 1 |
| Brutus, M; Siegel, A; Zuabi, S | 2 |
| Cunningham, FJ; Stansfield, SC | 1 |
| Chouvet, G; Henriksen, SJ; Wiesner, JB | 1 |
| Gilbert, JA; Richelson, E | 1 |
| Bures, J; Koroleva, VI; Oitzl, MS | 1 |
| Rand, MJ; Wong-Dusting, HK | 1 |
| Bucarelli, A; De Montis, MG; Devoto, P; Tagliamonte, A | 1 |
| Kameyama, T; Matsuno, K; Nabeshima, T | 1 |
| Fukushima, M; Mizuno, S; Mori, A; Ogawa, N | 1 |
| Haddad, GG; Schaeffer, JI | 1 |
| Portoghese, PS; Takemori, AE | 1 |
| Biondi, C; Borasio, PG; Capuzzo, A; Ferretti, ME | 1 |
| Starr, MS | 1 |
| Laubie, M; Schmitt, H | 1 |
| Kamei, H; Kameyama, T; Matsuno, K; Nabeshima, T; Noda, Y | 1 |
| Borsodi, A; Toth, G | 1 |
| Greenspan, DL; Musacchio, JM | 1 |
| Kotlińska, J; Langwiński, R | 1 |
| Duffy, P; Kalivas, PW; Latimer, LG | 1 |
| Hashimoto, K; Hattori, T; Inoue, H; Kageyama, J; Ota, Z; Suemaru, S; Sugawara, M; Takao, T | 1 |
| Madamba, SG; Moore, SD; Siggins, GR; Zieglgänsberger, W | 1 |
| Barnett, A; Berger, JG; Billard, W; Chapman, R; Chipkin, RE; Iorio, LC | 1 |
| Aicher, SA; Randich, A | 1 |
| Kraras, CM; Lathers, CM; Tumer, N | 1 |
| Del Rio, J; Fernandez-Tome, MP; Gonzalez, Y | 1 |
| Schwartz, JP | 1 |
| Frank, GB; Sudha, TS | 1 |
| Haddad, GG; Jeng, HJ; Lai, TL | 1 |
| Jourdan, ML; Lee, TF; Wang, LC | 1 |
| Kramer, SZ; Pott, CB; Siegel, A | 1 |
| Bentley, AM; Wallis, M | 1 |
| Chan, YS; Cheung, YM; Hwang, JC; Poon, PW; Wong, CL; Wong, TM | 1 |
| Matsuda, T; Mori, M; Tsushima, H | 1 |
| Bruni, P; Hewlett, EL; Moss, J | 1 |
| Agmo, A; de Avila, N | 1 |
| Asdourian, D; Geula, C | 1 |
| Kameyama, T; Matsuno, K; Nabeshima, T; Suzuki, M | 1 |
| Gluckman, PD; Taylor, KM; Villiger, JW | 1 |
| Groves, PM; Ling, N; Nakamura, S; Tepper, JM; Young, SJ | 1 |
| Gaginella, TS; Wu, ZC | 1 |
| Krieger, AJ; Punnen, S; Sapru, HN; Willette, RN | 1 |
| Sun, FY; Yu, GH; Zhang, AZ; Zhang, LM | 1 |
| Fields, HL; Hentall, ID | 1 |
| Groppetti, A; Olgiati, VR; Parenti, M; Tirone, F | 1 |
| Galetta, S; Ling, GS; Pasternak, GW | 1 |
| Huidobro, F; Huidobro-Toro, JP | 1 |
| Byrne, WL; Codd, EE | 1 |
| Coscia, CJ; Laskowski, MB; Roth, BL | 1 |
| Adler, MW; Cowan, A; Tortella, FC | 1 |
| Blume, AJ; Fantozzi, R; Mullikin-Kilpatrick, D | 1 |
| Appel, NM; Van Loon, GR | 1 |
| Pasternak, GW; Wolozin, BL | 1 |
| Cowan, A; Tortella, FC | 1 |
| Bernardini, GL; Clark, WG | 1 |
| Grace, M; Kneip, J; Levine, AS; Morley, JE; Murray, SS | 1 |
| Chesselet, MF; Glowinski, J; Lubetzki, C | 1 |
| Dunwiddie, TV; Palmer, MR; Perez-Reyes, E; Rice, KC | 1 |
| Assanah, P; Scharrer, B; Stefano, GB | 1 |
| Blume, AJ; Larsen, NE; Mullikin-Kilpatrick, D | 1 |
| Gaginella, TS; Rimele, TJ; Wietecha, M | 1 |
| Laurent, S; Schmitt, H | 1 |
| Chan, SH; Tse, SY; Wong, TM | 1 |
| Connor, JD; Drust, EG | 1 |
| Assanah, P; Burrowes, WR; Chapman, A; Gonzales, G; Iannone, B; Leung, MK; Stefano, GB | 1 |
| Copolov, D; Funder, JW; Jefferys, D | 1 |
| Chaillet, P; Costentin, J; Lecomte, JM; Marçais, H; Natan, LB; Uchida, G | 1 |
| Giovino, AA; Glimcher, PW; Hoebel, BG; Margolin, DH | 1 |
| de Groat, WC; Hisamitsu, T | 1 |
| Breese, G; Kalivas, PW; Prange, AJ; Stanley, D; Widerlöv, E | 1 |
| Gandhi, MR; Haddad, GG; Hochwald, GM; Lai, TL | 1 |
| Balderrama, N; Maldonado, H; Miralto, A; Núñez, J | 1 |
| Barnett, A; Chipkin, RE; Iorio, LC; Latranyi, MZ | 1 |
| Allerton, HW; Isom, GE; Zobrist, RH | 1 |
| Bellet, M; Elghozi, JL; Meyer, P | 1 |
| Chéramy, A; Chesselet, MF; Desban, M; Glowinski, J; Lubetzki, C; Reisine, TD | 1 |
| del Río, J; Garzón, J; Rubio, J | 1 |
| Brady, LS; Holtzman, SG | 1 |
| Bloom, FE; Iversen, SD; Joyce, EM; Koob, GF; Strecker, R | 1 |
| Macdonald, RL; Werz, MA | 1 |
| LePiane, FG; Phillips, AG | 1 |
| Flack, HG; Huston, JP; Welzl, H | 1 |
| Huston, JP; Oitzl, MS; Ornstein, K; Sprick, U | 1 |
| Chéramy, A; Chesselet, MF; Glowinski, J; Reisine, TD | 1 |
| Khan, MF | 1 |
| Coy, DH; Dunlap, WP; Harston, CT; Spirtes, MA | 1 |
| Adjroud, O | 1 |
| Capron, A; Duvaux-Miret, O; Leung, MK; Stefano, GB | 1 |
| Casares, F; Liu, U; Stefano, GB | 1 |
| Parenti, C; Scoto, GM | 1 |
| Abe, T; Kotegawa, T; Tsutsui, K | 1 |
| Cui, Y; Lee, TF; Wang, LC | 1 |
| Bhatia, SC; Manchanda, SK; Nayar, U; Saha, SN | 1 |
| Severson, K; Tackett, RL | 1 |
| Fukunaga, Y; Inoue, N; Kishioka, S; Miyamoto, M; Yamamoto, H | 1 |
| Bergasa, NV; Ravi, J; Shi, Q; Zhou, J | 1 |
| Ally, A; Chayaikul, P; Ishide, T; Maher, TJ; Mancini, M | 1 |
| Ally, A; Maher, TJ; Nauli, SM; Pearce, WJ | 1 |
| Schneider, JS; Schroeder, JA | 1 |
| Barson, JR; Hoebel, BG; Leibowitz, SF; Rada, P | 1 |
| Barson, JR; Carr, AJ; Hoebel, BG; Leibowitz, SF; Rada, P; Sobhani, NC; Soun, JE | 1 |
| Barson, JR; Chen, A; Chen, YW; Hoebel, BG; Leibowitz, SF | 1 |
2 review(s) available for enkephalinamide-met, ala(2)- and naloxone
| Article | Year |
|---|---|
Opioids in the hippocampus: progress obtained from in vivo electrophysiological analyses.
Topics: Animals; beta-Endorphin; Electroencephalography; Electrophysiology; Endorphins; Enkephalin, Methionine; Hippocampus; Immunohistochemistry; Naloxone | 1988 |
[Enkephalinergic regulation of cardiovascular centers].
Topics: Animals; Blood Pressure; Brain Mapping; Cardiovascular Physiological Phenomena; Cats; Dextromoramide; Dogs; Enkephalin, Methionine; Enkephalins; Heart Rate; Medulla Oblongata; Naloxone; Naltrexone; Nervous System Physiological Phenomena; Pressoreceptors; Rats; Receptors, Opioid; Reflex; Reticular Formation; Sympathetic Nervous System; Vagus Nerve; Vasomotor System | 1985 |
131 other study(ies) available for enkephalinamide-met, ala(2)- and naloxone
| Article | Year |
|---|---|
Opioid inhibition of GABA release from presynaptic terminals of rat hippocampal interneurons.
Topics: Action Potentials; Animals; Electric Conductivity; Electric Stimulation; Enkephalin, Methionine; gamma-Aminobutyric Acid; Hippocampus; Interneurons; Male; Molecular Sequence Data; Naloxone; Rats; Rats, Inbred Strains; Synapses; Tetrodotoxin | 1992 |
Effects of beta-adrenergic blocking agents on specific binding of [3H]D-Ala2-Met5-enkephalinamide and [3H]naloxone.
Topics: Adrenergic beta-Antagonists; Animals; Enkephalin, Methionine; In Vitro Techniques; Male; Naloxone; Rats; Rats, Inbred Strains; Receptors, Opioid; Sodium | 1991 |
Neurokinin inhibition of cholinergic myenteric neurons in canine antrum.
Topics: Acetylcholine; Animals; Atropine; Dinoprostone; Dogs; Electric Stimulation; Enkephalin, Methionine; Female; Hexamethonium; Hexamethonium Compounds; In Vitro Techniques; Indomethacin; Male; Muscle, Smooth; Myenteric Plexus; Naloxone; Neurokinin A; Neurons; Nifedipine; Phentolamine; Propranolol; Pyloric Antrum; Substance P; Tetrodotoxin; Vasoactive Intestinal Peptide | 1990 |
Opioid modulation of pavlovian learning in rabbits: involvement of sublenticular pathways.
Topics: Animals; Association Learning; Attention; Conditioning, Classical; Discrimination Learning; Enkephalin, Methionine; Extinction, Psychological; Female; Heart Rate; Male; Naloxone; Rabbits; Substantia Innominata | 1991 |
Lipopolysaccharide and opioids activate distinct populations of Mytilus edulis immunocytes.
Topics: Animals; Bivalvia; Enkephalin, Methionine; Hemocytes; Lipopolysaccharides; Naloxone | 1991 |
Changes in cardiovascular responses of conscious rats to endogenous opioids following treatment with catecholamine-depleting agents.
Topics: Animals; Atropine; Blood Pressure; Cardiovascular Physiological Phenomena; Catecholamines; Dynorphins; Endorphins; Enkephalin, Methionine; Heart Rate; Hydroxydopamines; Male; Motor Activity; Naloxone; Narcotics; Neurotoxins; Oxidopamine; Peptide Fragments; Rats; Rats, Inbred Strains; Reserpine; Verapamil | 1990 |
Opioid induction of immunoreactive interleukin-1 in Mytilus edulis and human immunocytes: an interleukin-1-like substance in invertebrate neural tissue.
Topics: Animals; Bivalvia; Enkephalin, Methionine; Ganglia; Glycopeptides; Humans; Immune System; Interleukin-1; Naloxone; Nerve Tissue | 1991 |
The proabsorptive effect of D-ala2-metenkephalinamide is mediated by naloxone-sensitive opiate receptors in the isolated perfused ileum.
Topics: Absorption; Animals; Dose-Response Relationship, Drug; Electrolytes; Enkephalin, Methionine; Ileum; In Vitro Techniques; Naloxone; Perfusion; Rabbits; Receptors, Opioid; Water | 1990 |
Opioid peptide regulation of neurons in the bed nucleus of the stria terminalis: a microiontophoretic study.
Topics: Animals; Electrophysiology; Enkephalin, Methionine; Female; Iontophoresis; Naloxone; Neurons; Rats; Rats, Inbred Strains; Thalamus | 1990 |
Role of naloxone and opioid peptides on thyrotrophin, alpha subunit and beta thyrotrophin by dispersed rat pituitary cells.
Topics: Animals; beta-Endorphin; Cells, Cultured; Endorphins; Enkephalin, Methionine; Glycoprotein Hormones, alpha Subunit; Male; Naloxone; Peptide Fragments; Pituitary Gland; Pituitary Hormones, Anterior; Rats; Rats, Inbred Strains; Receptors, Opioid; Thyrotropin; Thyrotropin-Releasing Hormone; Triiodothyronine | 1985 |
Neurokinin B is a preferred agonist for a neuronal substance P receptor and its action is antagonized by enkephalin.
Topics: Animals; Atropine; Enkephalin, Methionine; Guinea Pigs; Ileum; Muscle Contraction; Muscle, Smooth; Naloxone; Nerve Tissue Proteins; Neurokinin A; Neurokinin B; Neurons; Neurotransmitter Agents; Oligopeptides; Peptide Fragments; Receptors, Muscarinic; Receptors, Neurokinin-1; Receptors, Neurotransmitter; Substance P; Substrate Specificity; Tachykinins | 1985 |
Enkephalins increase cyclic adenosine monophosphate content, calcium uptake, and contractile state in cultured chick embryo heart cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Calcium; Cells, Cultured; Chick Embryo; Cyclic AMP; Enkephalin, Methionine; Enkephalins; GTP-Binding Proteins; Heart; Myocardial Contraction; Myocardium; Naloxone | 1986 |
Effects of opioids and opioid peptide on the release of substance P-like material induced by tooth pulp stimulation in the trigeminal nucleus caudalis of the rabbit.
Topics: Animals; Dental Pulp; Electric Stimulation; Enkephalin, Methionine; Male; Morphine; Naloxone; Pain; Rabbits; Substance P; Trigeminal Nuclei | 1986 |
Inhibition of sympathetic neurotransmission by the opioid delta-receptor agonist DAMA in the pithed rat.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Blood Pressure; Decerebrate State; Electric Stimulation; Enkephalin, Methionine; Male; Naloxone; Nerve Endings; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Spinal Cord; Sympathetic Nervous System; Synaptic Transmission | 1989 |
Evidence for the involvement of opioid neuropeptides in the adherence and migration of immunocompetent invertebrate hemocytes.
Topics: Animals; Blood Cells; Cell Adhesion; Cell Movement; Chromatography, High Pressure Liquid; Cockroaches; Endorphins; Enkephalin, Methionine; Female; Hemocytes; Male; Mollusca; Naloxone; Radioimmunoassay; Receptors, Opioid | 1989 |
Inhibition of stimulated lacrimal secretion by [D-Ala2]Met-enkephalinamide.
Topics: Animals; Carbachol; Dose-Response Relationship, Drug; Drug Synergism; Enkephalin, Methionine; Kinetics; Lacrimal Apparatus; Male; Naloxone; Peroxidase; Phenylephrine; Rats; Rats, Inbred F344; Vasoactive Intestinal Peptide | 1989 |
Kappa-opioid agonists do not inhibit adenylate cyclase.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adenylyl Cyclase Inhibitors; Animals; Benzeneacetamides; Benzomorphans; Binding, Competitive; Brain; Cell Membrane; Enkephalin, Methionine; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Levorphanol; Morphine; Naloxone; Pentazocine; Pyrrolidines; Rana catesbeiana; Receptors, Opioid; Receptors, Opioid, kappa; Sodium Chloride | 1989 |
Modulation of mu-mediated antinociception by delta agonists: characterization with antagonists.
Topics: Analgesics; Animals; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Methionine; Enkephalins; Injections, Intraventricular; Male; Mice; Mice, Inbred ICR; Naloxone; Naltrexone; Narcotic Antagonists; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu | 1989 |
Opposite central and peripheral control by endogenous opioids of intestinal motility in fed rats.
Topics: Administration, Oral; Animals; Captopril; Electromyography; Endorphins; Enkephalin, Methionine; Gastrointestinal Motility; Glycopeptides; Injections, Intraperitoneal; Injections, Intraventricular; Levallorphan; Male; Naloxone; Rats; Rats, Inbred Strains | 1989 |
Role of renal nerves in excretory responses to exogenous and endogenous opioid peptides.
Topics: Animals; Body Water; Denervation; Endorphins; Enkephalin, Methionine; Hemodynamics; Kidney; Male; Naloxone; Rats; Rats, Inbred Strains; Sodium; Sympathetic Nervous System | 1989 |
Opioid modulation of feeding and drinking in fowls.
Topics: Animals; Chickens; Drinking; Eating; Enkephalin, Methionine; Female; Injections, Intramuscular; Injections, Intravenous; Injections, Intraventricular; Naloxone; Naltrexone; Time Factors | 1989 |
Hypothalamo-pituitary-interrenal responses to opioid substances in the trout. II. Effects of morphine and D-Ala2, Met5-enkephalinamide on plasma cortisol titres in vivo.
Topics: Adrenocorticotropic Hormone; Aging; Animals; Corticotropin-Releasing Hormone; Enkephalin, Methionine; Hydrocortisone; Hypothalamus; Interrenal Gland; Morphine; Naloxone; Pituitary Gland, Anterior; Salmonidae; Time Factors; Trout | 1987 |
Opiate-inhibited adenylate cyclase in rat brain membranes depleted of Gs-stimulated adenylate cyclase.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Animals; Brain; Cell Membrane; Cholera Toxin; Colforsin; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; GTP-Binding Proteins; Guanine Nucleotides; Guanylyl Imidodiphosphate; Hydrogen-Ion Concentration; Male; Naloxone; Oligopeptides; Pertussis Toxin; Rats; Rats, Inbred Strains; Receptors, Opioid; Sodium Fluoride; Virulence Factors, Bordetella | 1988 |
Effects of the opioid peptides [Met5]enkephalin-Arg6-Phe7 and [Met5]enkephalin-Arg6-Gly7-Leu8 on cholinergic neurotransmission in the rabbit isolated atria.
Topics: Animals; Electric Stimulation; Enkephalin, Leucine; Enkephalin, Methionine; Female; Heart; Heart Rate; In Vitro Techniques; Male; Naloxone; Parasympathetic Nervous System; Propranolol; Rabbits; Synaptic Transmission | 1987 |
Opiate mechanisms in the central amygdala and gastric stress pathology in rats.
Topics: Amygdala; Animals; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Male; Microinjections; Naloxone; Rats; Rats, Inbred Strains; Receptors, Opioid; Restraint, Physical; Stomach Ulcer; Stress, Physiological | 1988 |
Monoclonal antibody to enkephalins with binding characteristics similar to opiate receptor.
Topics: alpha-Endorphin; Animals; Antibodies, Monoclonal; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Enkephalins; Mice; Morphine; Naloxone; Receptors, Opioid | 1985 |
Sensitization to repeated enkephalin administration into the ventral tegmental area of the rat. I. Behavioral characterization.
Topics: Animals; Behavior, Animal; Conditioning, Classical; Dose-Response Relationship, Drug; Drug Administration Schedule; Dynorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Male; Microinjections; Motor Activity; Naloxone; Peptide Fragments; Rats; Rats, Inbred Strains; Tegmentum Mesencephali | 1985 |
[Peripheral analgesic actions of opioid peptides and morphine analogues].
Topics: Analgesics, Opioid; Animals; Cyclazocine; Dynorphins; Enkephalin, Methionine; Ethylketocyclazocine; Levallorphan; Lidocaine; Male; Mice; Morphine; Naloxone; Pain; Peptide Fragments | 1986 |
Binding characteristics of [3H]opioid ligands to active opioid binding sites solubilized from rat brain membranes by glycodeoxycholate and NaCl: the recovery of binding activity by dilution.
Topics: Animals; Brain; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Methionine; Enkephalins; Glycodeoxycholic Acid; Male; Naloxone; Peptide Fragments; Rats; Rats, Inbred Strains; Receptors, Opioid; Sodium Chloride; Solutions | 1987 |
Stimulation of opiate receptors in the dorsal pontine tegmentum inhibits reflex contraction of the urinary bladder.
Topics: Animals; Enkephalin, Methionine; Fentanyl; Glutamates; Glutamic Acid; Microinjections; Muscle Contraction; Naloxone; Narcotic Antagonists; Pressure; Rats; Receptors, Opioid; Reflex; Tegmentum Mesencephali; Urinary Bladder | 1988 |
Microinjections of D-Ala2-Met5-enkephalinamide placed into nucleus accumbens suppress hypothalamically elicited hissing in the cat.
Topics: Aggression; Animals; Cats; Caudate Nucleus; Enkephalin, Methionine; Female; Hypothalamus; Male; Microinjections; Naloxone; Nucleus Accumbens; Reference Values; Septal Nuclei; Time Factors; Vocalization, Animal | 1989 |
Direct action of opioid peptides and naloxone on gonadotropin secretion by cultured rat anterior pituitary cells.
Topics: Animals; beta-Endorphin; Cells, Cultured; Endorphins; Enkephalin, Methionine; Follicle Stimulating Hormone; Luteinizing Hormone; Naloxone; Narcotics; Pituitary Gland, Anterior; Rats | 1986 |
Modulation by endogenous opioid peptides of the secretion of LHRH from cockerel (Gallus domesticus) mediobasal hypothalamic tissue.
Topics: Animals; beta-Endorphin; Chickens; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Gonadotropin-Releasing Hormone; Hypothalamus; In Vitro Techniques; Male; Naloxone | 1987 |
Influence of delta-opioid receptors on production of labeled methionine5-enkephalin in murine neuroblastoma cells.
Topics: Animals; Cell Line; Chromatography, High Pressure Liquid; Cycloheximide; Enkephalin, Methionine; Mice; Naloxone; Neuroblastoma; Puromycin; Rabbits; Receptors, Opioid; Receptors, Opioid, delta; Time Factors | 1985 |
D-ala2-Metenkephalinamide blocks the synaptically elicited cortical spreading depression in rats.
Topics: Aminopyridines; Animals; Cerebral Cortex; Enkephalin, Methionine; Male; Membrane Potentials; Naloxone; Neural Inhibition; Potassium; Rats; Synaptic Transmission | 1985 |
Effect of [D-Ala2,Met5]enkephalinamide and [D-Ala2,D-Leu5]enkephalin on cholinergic and noradrenergic neurotransmission in isolated atria.
Topics: Acetylcholine; Animals; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Female; Guinea Pigs; Heart Atria; In Vitro Techniques; Male; Naloxone; Norepinephrine; Rabbits; Rats; Synaptic Transmission; Tetrodotoxin | 1985 |
Opioid activity of lefetamine.
Topics: Anesthetics, Local; Animals; Binding, Competitive; Brain; Cyclazocine; Enkephalin, Methionine; Ethylketocyclazocine; Lethal Dose 50; Male; Methadone; Mice; Morphine; Naloxone; Phenethylamines; Rats; Rats, Inbred Strains; Reaction Time; Receptors, Opioid | 1985 |
Involvement of different opioid receptor subtypes in electric shock-induced analgesia and motor suppression in the rat.
Topics: Animals; Cyclazocine; Electroshock; Enkephalin, Methionine; Ethylketocyclazocine; Male; Motor Activity; Naloxone; Pain; Phencyclidine; Rats; Rats, Inbred Strains; Receptors, Opioid; Time Factors | 1985 |
Effects of guanine nucleotides, transition metals and temperature on enkephalin receptors of rat brain membranes.
Topics: Adenine Nucleotides; Animals; Brain; Copper; Enkephalin, Methionine; Guanine Nucleotides; Kinetics; Male; Naloxone; Rats; Rats, Inbred Strains; Receptors, Opioid; Synaptic Membranes; Temperature; Thermodynamics; Zinc | 1985 |
Regulation of ventilation and oxygen consumption by delta- and mu-opioid receptor agonists.
Topics: Animals; Blood Gas Analysis; Carbon Dioxide; Dogs; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Hydrogen-Ion Concentration; Naloxone; Oxygen; Oxygen Consumption; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Respiration | 1985 |
Receptors for opioid peptides in the guinea-pig ileum.
Topics: Alkylation; Animals; Dose-Response Relationship, Drug; Electric Stimulation; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Enkephalins; Guinea Pigs; Ileum; Male; Mice; Naloxone; Naltrexone; Oligopeptides; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Vas Deferens | 1985 |
[Opiate regulation of cyclic AMP levels in sympathetic ganglia in mammals].
Topics: Animals; Cyclic AMP; Dinoprostone; Enkephalin, Methionine; Ganglia, Sympathetic; Guinea Pigs; Morphine; Naloxone; Narcotics; Prostaglandins E; Rabbits; Rats; Rats, Inbred Strains | 1985 |
Multiple opiate receptors may be involved in suppressing gamma-aminobutyrate release in substantia nigra.
Topics: Aminooxyacetic Acid; Animals; Benzomorphans; Dopamine; Enkephalin, Methionine; Female; gamma-Aminobutyric Acid; Male; Naloxone; Nialamide; Phenazocine; Rats; Rats, Inbred Strains; Receptors, Opioid; Secretory Rate; Substantia Nigra | 1985 |
Electric footshock-induced changes in behavior and opioid receptor function.
Topics: Analgesia; Animals; Behavior, Animal; Binding, Competitive; Electroshock; Enkephalin, Methionine; Kinetics; Male; Motor Activity; Naloxone; Pain; Rats; Rats, Inbred Strains; Receptors, Opioid; Sensory Thresholds; Synaptic Membranes | 1985 |
Microtubule disassembly increases the number of opioid receptor binding sites in rat cerebrum membranes.
Topics: Animals; Brain; Cell Membrane; Dihydromorphine; Enkephalin, Methionine; Kinetics; Levorphanol; Microtubules; Naloxone; Podophyllotoxin; Rats; Receptors, Opioid | 1986 |
The adenylate cyclase rebound response to naloxone in the NG108-15 cells. Effects of etorphine and other opiates.
Topics: Adenylyl Cyclases; Alprostadil; Cell Line; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Etorphine; Glioma; Morphinans; Morphine; Naloxone; Neuroblastoma; Receptors, Opioid | 1986 |
Audiogenic seizures during ethanol withdrawal can be blocked by a delta opioid agonist.
Topics: Acoustic Stimulation; Animals; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Ethanol; Female; Naloxone; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Seizures; Substance Withdrawal Syndrome | 1986 |
Mu opioid receptor involvement in enkephalin activation of dopamine neurons in the ventral tegmental area.
Topics: Animals; Dopamine; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Methionine; Enkephalins; Male; Motor Activity; Naloxone; Neurons; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, mu; Tegmentum Mesencephali | 1987 |
Effects of (D-ala2, met5)-enkephalinamide and naloxone on ACTH and corticosterone secretion.
Topics: Adrenocorticotropic Hormone; Animals; Corticosterone; Enkephalin, Methionine; Injections, Intravenous; Male; Naloxone; Rats; Secretory Rate | 1986 |
Enkephalin analogues depress synaptic potentials in rat dentate granule cells recorded intracellularly in vitro.
Topics: Action Potentials; Animals; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Hippocampus; In Vitro Techniques; Male; Naloxone; Rats; Rats, Inbred Strains | 1988 |
Pharmacology of SCH 34826, an orally active enkephalinase inhibitor analgesic.
Topics: Administration, Oral; Analgesics; Animals; Dioxolanes; Dioxoles; Dipeptides; Drug Synergism; Enkephalin, Methionine; Gastrointestinal Motility; Male; Metalloendopeptidases; Mice; Naloxone; Neprilysin; Rats; Respiration | 1988 |
Effects of intrathecal antagonists on the antinociception, hypotension, and bradycardia produced by intravenous administration of [D-Ala2]-methionine enkephalinamide (DALA) in the rat.
Topics: Analgesics; Animals; Antihypertensive Agents; Endorphins; Enkephalin, Methionine; Heart Rate; Injections, Spinal; Male; Methysergide; Naloxone; Norepinephrine; Phentolamine; Rats; Rats, Inbred Strains; Serotonin | 1988 |
Effects of D-Ala2-Met5-enkephalinamide microinjections placed into the bed nucleus of the stria terminalis upon affective defense behavior in the cat.
Topics: Amygdala; Animals; Behavior, Animal; Cats; Enkephalin, Methionine; Female; Hypothalamus, Middle; Male; Microinjections; Naloxone; Reaction Time | 1988 |
The effect of intracerebroventricular D-ALA2 methionine enkephalinamide and naloxone on cardiovascular parameters in the cat.
Topics: Animals; Blood Pressure; Cats; Cerebral Ventricles; Enkephalin, Methionine; Epilepsy; Heart; Heart Conduction System; Heart Rate; Injections, Intraventricular; Models, Neurological; Naloxone; Pentylenetetrazole; Reference Values | 1988 |
Interaction between opioid agonists or naloxone and 5-HTP on feeding behavior in food-deprived rats.
Topics: 5-Hydroxytryptophan; Animals; D-Ala(2),MePhe(4),Met(0)-ol-enkephalin; Drug Interactions; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Feeding Behavior; Food Deprivation; Male; Morphine; Naloxone; Narcotics; Rats; Rats, Inbred Strains | 1988 |
Chronic exposure to opiate agonists increases proenkephalin biosynthesis in NG108 cells.
Topics: Animals; Cell Line; Colforsin; Enkephalin, Methionine; Enkephalins; Etorphine; Genes; Glioma; Hybrid Cells; Morphinans; Morphine; Naloxone; Neuroblastoma; Protein Precursors; RNA, Messenger; Transcription, Genetic | 1988 |
Effects of enkephalin, applied intracellularly, on action potentials in vertebrate A and C nerve fibre axons.
Topics: Action Potentials; Animals; Enkephalin, Leucine; Enkephalin, Methionine; Guinea Pigs; In Vitro Techniques; Naloxone; Nerve Fibers; Nerve Fibers, Myelinated; Rabbits; Rana pipiens; Sciatic Nerve; Vagus Nerve | 1987 |
Effect of endorphins on heart rate and blood pressure in adult dogs.
Topics: Animals; Atropine; Blood Pressure; Consciousness; Dogs; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Heart; Heart Rate; Naloxone; Naltrexone | 1986 |
Seasonal difference in thermoregulatory responses to opiates in a mammalian hibernator.
Topics: Animals; Body Temperature Regulation; Enkephalin, Methionine; Female; Hibernation; Injections, Intraventricular; Morphine; Naloxone; Oxygen Consumption; Sciuridae; Seasons | 1987 |
Central gray modulation of affective defense is differentially sensitive to naloxone.
Topics: Aggression; Animals; Cats; Electric Stimulation; Enkephalin, Methionine; Female; Naloxone; Periaqueductal Gray; Ventromedial Hypothalamic Nucleus | 1987 |
Effects of two enkephalin analogues, morphine sulphate, dopamine and naloxone on prolactin secretion from rat anterior pituitary glands in vitro.
Topics: Animals; Depression, Chemical; Dopamine; Dose-Response Relationship, Drug; Enkephalin, Leucine; Enkephalin, Methionine; Female; Morphine; Naloxone; Narcotics; Organ Culture Techniques; Perfusion; Pituitary Gland, Anterior; Prolactin; Rats; Rats, Inbred Strains; Time Factors | 1986 |
Effects of superfusion of morphine and enkephalins on the activity of single units in the spinal trigeminal nucleus and cuneate nucleus of cat.
Topics: Action Potentials; Animals; Cats; Electrophysiology; Enkephalin, Methionine; Enkephalins; Female; Male; Medulla Oblongata; Morphine; Naloxone; Trigeminal Nucleus, Spinal | 1986 |
Antidiuretic effects of methionine-enkephalin and 2-D-alanine-5-methionine-enkephalinamide microinjected into the hypothalamic supraoptic and paraventricular nuclei in a water-loaded and ethanol-anesthetized rat.
Topics: Anesthesia; Animals; Atropine; Diuresis; Dose-Response Relationship, Drug; Enkephalin, Methionine; Ethanol; Male; Microinjections; Naloxone; Osmotic Pressure; Paraventricular Hypothalamic Nucleus; Phenoxybenzamine; Rats; Rats, Inbred Strains; Supraoptic Nucleus; Viscera | 1986 |
Effects of pertussis toxin-catalyzed ADP-ribosylation on interactions of transducin and the inhibitory GTP-binding protein of adenylate cyclase with guanyl nucleotides.
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Animals; Atropine; Bacterial Toxins; Carbachol; Cell Line; Cell Membrane; Enkephalin, Methionine; GTP-Binding Proteins; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Membrane Proteins; Naloxone; Norepinephrine; Nucleoside Diphosphate Sugars; Pertussis Toxin; Phentolamine; Transducin; Virulence Factors, Bordetella | 1985 |
Interactions between enkephalin and dopamine in the control of locomotor activity in the rat: a new hypothesis.
Topics: Amphetamine; Animals; Dopamine; Drug Interactions; Enkephalin, Methionine; Enkephalins; Injections, Intraventricular; Male; Motor Activity; Naloxone; Pimozide; Rats; Rats, Inbred Strains; Time Factors | 1985 |
Asymmetric behavior induced by enkephalinergic agents in the basal ganglia.
Topics: Animals; Behavior, Animal; Dose-Response Relationship, Drug; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; Ganglia, Spinal; Male; Naloxone; Naltrexone; Rats; Rats, Inbred Strains | 1985 |
Different changes by acute electric footshock of opioid agonist and antagonist receptors in rat brain.
Topics: Animals; Brain; Dihydromorphine; Electroshock; Enkephalin, Methionine; Male; Morphine Derivatives; Naloxone; Rats; Receptors, Opioid | 1984 |
Ontogenesis of opiate receptors in regions of the ovine brain.
Topics: Age Factors; Animals; Binding Sites; Brain; Enkephalin, Methionine; Naloxone; Receptors, Opioid; Sheep | 1982 |
Noradrenergic terminal excitability: effects of opioids.
Topics: Animals; Dose-Response Relationship, Drug; Endorphins; Enkephalin, Methionine; Enkephalins; Frontal Lobe; Locus Coeruleus; Male; Morphine; Naloxone; Neurotransmitter Agents; Rats; Rats, Inbred Strains; Reaction Time; Receptors, Opioid | 1982 |
[D-Ala2,D-Met5NH2]-enkephalin inhibits acetylcholine release from the submucosal plexus of rat colon.
Topics: Acetylcholine; Animals; Colon; Enkephalin, Methionine; In Vitro Techniques; Intestinal Mucosa; Morphine; Naloxone; Rats | 1983 |
Hypertensive response following stimulation of opiate receptors in the caudal ventrolateral medulla.
Topics: Animals; Blood Pressure; Carotid Arteries; Enkephalin, Methionine; Glutamates; Glutamic Acid; Heart Rate; Male; Medulla Oblongata; Naloxone; Rats; Rats, Inbred Strains; Receptors, Opioid | 1984 |
[Inhibitory effects of dynorphin on electric field stimulation induced contraction of blood vessels in vitro].
Topics: Animals; Dogs; Dynorphins; Ear; Electric Stimulation; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; In Vitro Techniques; Mesenteric Arteries; Naloxone; Rabbits; Receptors, Opioid; Vasoconstriction | 1984 |
Actions of opiates, substance P, and serotonin on the excitability of primary afferent terminals and observations on interneuronal activity in the neonatal rat's dorsal horn in vitro.
Topics: Afferent Pathways; Animals; Culture Techniques; Dose-Response Relationship, Drug; Enkephalin, Methionine; Evoked Potentials; gamma-Aminobutyric Acid; Ganglia, Spinal; Interneurons; Morphine; Naloxone; Rats; Serotonin; Spinal Cord; Spinal Nerve Roots; Substance P; Synaptic Transmission | 1983 |
Presence of opiate receptors on striatal serotoninergic nerve terminals.
Topics: Animals; Corpus Striatum; Dopamine; Enkephalin, Methionine; Fenfluramine; Hydroxyindoleacetic Acid; Male; Morphine; Naloxone; Nerve Degeneration; Neurons; Rats; Rats, Inbred Strains; Receptors, Opioid; Serotonin | 1983 |
Oxymorphazone: a long-acting opiate analgesic.
Topics: Analgesia; Animals; Brain; Dose-Response Relationship, Drug; Drug Tolerance; Enkephalin, Methionine; Hydromorphone; Injections, Intraventricular; Morphine; Naloxone; Oxymorphone; Rats; Receptors, Opioid; Time Factors | 1984 |
Central effects of morphine, levorphanol, (-)-methadone and the opioid-like peptides beta-endorphin and D-alanine2- methionine enkephalinamide on urine volume outflow and electrolytes.
Topics: Animals; beta-Endorphin; Brain; Diuresis; Electrolytes; Endorphins; Enkephalin, Methionine; Enkephalins; Female; Levorphanol; Male; Methadone; Morphine; Naloxone; Narcotics; Rats; Vasopressins | 1981 |
Seasonal variation in the apparent number of binding sites for 3H-opioid agonists and antagonists.
Topics: Animals; Binding Sites; Brain; Dihydromorphine; Endorphins; Enkephalin, Methionine; Enkephalins; Female; Kinetics; Male; Mice; Morphinans; Morphine; Naloxone; Naltrexone; Receptors, Opioid; Seasons | 1981 |
Evidence for distinct subcellular sites of opiate receptors. Demonstration of opiate receptors in smooth microsomal fractions isolated from rat brain.
Topics: Animals; Binding, Competitive; Brain; Cell Fractionation; Enkephalin, Methionine; Enkephalins; Guanylyl Imidodiphosphate; Kinetics; Microscopy, Electron; Microsomes; Naloxone; Rats; Receptors, Opioid; Subcellular Fractions | 1981 |
Comparison of the anticonvulsant effects of opioid peptides and etorphine in rats after icv administration.
Topics: Animals; Anticonvulsants; beta-Endorphin; Dose-Response Relationship, Drug; Endorphins; Enkephalin, Methionine; Enkephalins; Etorphine; Flurothyl; Male; Morphinans; Naloxone; Rats; Rats, Inbred Strains; Seizures; Structure-Activity Relationship | 1981 |
Irreversible inactivation of the opiate receptors in the neuroblastoma x glioma hybrid NG108-15 by chlornaltrexamine.
Topics: Animals; Cyclic AMP; Enkephalin, Methionine; Enkephalins; Glioma; Hybrid Cells; Mice; Naloxone; Naltrexone; Neoplasms, Experimental; Neuroblastoma; Nitrogen Mustard Compounds; Prostaglandins E, Synthetic; Rats; Receptors, Opioid | 1981 |
Plasma norepinephrine, epinephrine and dopamine responses to intracerebral administration of a met-enkephalin analog, D-ala2-met-enkephalinamide, in rats.
Topics: Animals; beta-Endorphin; Cisterna Magna; Dopamine; Endorphins; Enkephalin, Methionine; Enkephalins; Epinephrine; Injections; Injections, Intra-Arterial; Male; Naloxone; Norepinephrine; Rats; Rats, Inbred Strains | 1981 |
Classification of multiple morphine and enkephalin binding sites in the central nervous system.
Topics: Animals; Binding, Competitive; Brain; Cell Membrane; Endorphins; Enkephalin, Methionine; Enkephalins; Kinetics; Morphine; Naloxone; Rats; Receptors, Opioid; Structure-Activity Relationship | 1981 |
A quantitative analysis of the shaking behavior induced in rats by beta-endorphin and [D-Ala2, Met5]enkephalinamide.
Topics: Animals; Behavior, Animal; beta-Endorphin; Dose-Response Relationship, Drug; Drug Tolerance; Endorphins; Enkephalin, Methionine; Enkephalins; Male; Morphine; Naloxone; Rats; Rats, Inbred Strains | 1982 |
Morphine-induced hyperthermia: lack of cross-tolerance with enkephalin analogs.
Topics: Animals; Body Temperature Regulation; Cats; D-Ala(2),MePhe(4),Met(0)-ol-enkephalin; Dose-Response Relationship, Drug; Drug Tolerance; Endorphins; Enkephalin, Methionine; Enkephalins; Morphine; Naloxone; Pentazocine; Receptors, Opioid | 1982 |
Peptidergic regulation of stress-induced eating.
Topics: Animals; Appetite Depressants; Atropine; Bombesin; Carbachol; Cholecystokinin; Enkephalin, Methionine; Enkephalins; Feeding Behavior; Haloperidol; Humans; Isoproterenol; Male; Muscimol; Naloxone; Norepinephrine; Peptide Fragments; Peptides; Phentolamine; Quipazine; Rats; Rats, Inbred Strains; Sincalide; Stress, Psychological | 1982 |
Modulation of dopamine release in rat striatal slices by delta opiate agonists.
Topics: Animals; Corpus Striatum; Dopamine; Endorphins; Enkephalin, Methionine; Enkephalins; In Vitro Techniques; Male; Morphine; Naloxone; Narcotics; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Tetrodotoxin | 1982 |
Stereoselectivity of opiate antagonists in rat hippocampus and neocortex: responses to (+) and (-) isomers of naloxone.
Topics: Animals; Culture Techniques; Dose-Response Relationship, Drug; Enkephalin, Methionine; Evoked Potentials; Frontal Lobe; gamma-Aminobutyric Acid; Hippocampus; Male; Naloxone; Rats; Rats, Inbred Strains; Receptors, Opioid; Stereoisomerism; Synaptic Transmission | 1982 |
Demonstration, characterization and localization of opioid binding sites in the midgut of the insect Leucophaea maderae (Blattaria).
Topics: Animals; Autonomic Nervous System; Cockroaches; Denervation; Digestive System; Enkephalin, Methionine; Naloxone; Neurons; Receptors, Opioid | 1982 |
Protection of opiate receptors in NG108-15 against modification by N-ethylmaleimide.
Topics: Animals; Cell Line; Dithiothreitol; Enkephalin, Methionine; Ethylmaleimide; Glioma; Hybrid Cells; Kinetics; Mice; Naloxone; Naltrexone; Neuroblastoma; Rats; Receptors, Opioid; Sulfhydryl Reagents | 1983 |
Studies on rat intestinal epithelial cell receptors for serotonin and opiates.
Topics: Animals; Binding, Competitive; Cell Membrane; Cerebral Cortex; Colon; Enkephalin, Methionine; Epithelium; Ileum; In Vitro Techniques; Lysergic Acid Diethylamide; Male; Methysergide; Naloxone; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Serotonin | 1983 |
Central cardiovascular effects of kappa agonists dynorphin-(1-13) and ethylketocyclazocine in the anaesthetized rat.
Topics: Animals; beta-Endorphin; Blood Pressure; Cyclazocine; Dynorphins; Endorphins; Enkephalin, Methionine; Ethylketocyclazocine; Fentanyl; Heart Rate; Male; Naloxone; Peptide Fragments; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa; Vagus Nerve | 1983 |
Central cardiovascular actions of D-Ala2-Met5-enkephalinamide in the rat: effects of naloxone and nucleus reticularis gigantocellularis lesion.
Topics: Animals; Blood Pressure; Drug Interactions; Enkephalin, Methionine; Kinetics; Male; Naloxone; Rats; Rats, Inbred Strains; Reticular Formation; Stereotaxic Techniques | 1984 |
Pharmacological analysis of shaking behavior induced by enkephalins, thyrotropin-releasing hormone or serotonin in rats: evidence for different mechanisms.
Topics: Animals; Behavior, Animal; Brain Chemistry; Dopamine; Dose-Response Relationship, Drug; Enkephalin, Methionine; Enkephalins; Male; Naloxone; Norepinephrine; Rats; Rats, Inbred Strains; Serotonin; Serotonin Antagonists; Thyrotropin-Releasing Hormone | 1983 |
Alterations in high-affinity binding characteristics and levels of opioids in invertebrate ganglia during aging: evidence for an opioid compensatory mechanism.
Topics: Adenylyl Cyclases; Aging; Animals; Bivalvia; Dopamine; Endorphins; Enkephalin, Methionine; Etorphine; Ganglia; Insecta; Naloxone; Sex Factors | 1984 |
Naloxone inhibits both glucocorticoid and [D-Ala2,Met5]enkephalinamide reversal of behavioural effect of adrenalectomy.
Topics: Adrenalectomy; Animals; Behavior, Animal; Dexamethasone; Enkephalin, Methionine; Glucocorticoids; Male; Naloxone; Rats; Rats, Inbred Strains; Swimming | 1984 |
Involvement of endogenous enkephalins in the mouse 'behavioral despair' test.
Topics: Aminopeptidases; Animals; Behavior, Animal; Enkephalin, Methionine; Enkephalins; Leucine; Male; Mice; Motor Activity; Naloxone; Protease Inhibitors; Thiorphan; Tiopronin | 1984 |
Endogenous opiate reward induced by an enkephalinase inhibitor, thiorphan, injected into the ventral midbrain.
Topics: Amino Acids, Sulfur; Animals; Endorphins; Enkephalin, Methionine; Female; Mesencephalon; Naloxone; Rats; Rats, Inbred Strains; Reward; Tegmentum Mesencephali; Thiorphan; Tiopronin | 1984 |
The inhibitory effect of opioid peptides and morphine applied intrathecally and intracerebroventricularly on the micturition reflex in the cat.
Topics: Animals; Cats; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Enkephalins; Female; Morphine; Naloxone; Oligopeptides; Reflex; Thiorphan; Tiopronin; Urination | 1984 |
Enkephalin action on the mesolimbic system: a dopamine-dependent and a dopamine-independent increase in locomotor activity.
Topics: Animals; Dopamine; Dose-Response Relationship, Drug; Enkephalin, Methionine; Limbic System; Male; Motor Activity; Naloxone; Neurons; Nucleus Accumbens; Rats; Rats, Inbred Strains | 1983 |
Enkephalin-induced changes in ventilation and ventilatory pattern in adult dogs.
Topics: Animals; Consciousness; Dogs; Enkephalin, Methionine; Naloxone; Narcotic Antagonists; Periodicity; Respiration; Rest; Tidal Volume; Time Factors | 1983 |
The stinging response of the honeybee: effects of morphine, naloxone and some opioid peptides.
Topics: Animals; Bees; Behavior, Animal; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Insect Bites and Stings; Morphine; Naloxone | 1983 |
Potentiation of [D-ala2]enkephalinamide analgesia in rats by thiorphan.
Topics: Amino Acids, Sulfur; Analgesics; Animals; Drug Synergism; Enkephalin, Methionine; Male; Naloxone; Neprilysin; Nociceptors; Protease Inhibitors; Rats; Rats, Inbred Strains; Thiorphan; Time Factors; Tiopronin | 1982 |
Characterization of the respiratory activity of (D-Ala2)methionine-enkephalinamide.
Topics: Animals; Carbon Dioxide; Dose-Response Relationship, Drug; Drug Tolerance; Endorphins; Enkephalin, Methionine; Enkephalins; Male; Naloxone; Rats; Respiration; Respiratory Center; Time Factors | 1981 |
[Implication of enkephalins in central cardiovascular regulation in the rat].
Topics: Animals; Autonomic Nervous System; Blood Pressure; Diprenorphine; Endorphins; Enkephalin, Methionine; Enkephalins; Heart Rate; Hypertension; Injections, Spinal; Naloxone; Oxygen; Rats; Rats, Inbred Strains; Respiration | 1982 |
Local and distal effects induced by unilateral striatal application of opiates in the absence or in the presence of naloxone on the release of dopamine in both caudate nuclei and substantiae nigrae of the cat.
Topics: Animals; Cats; Caudate Nucleus; Corpus Striatum; Dopamine; Enkephalin, Methionine; Female; Fentanyl; Functional Laterality; Male; Morphine; Naloxone; Narcotics; Structure-Activity Relationship; Substantia Nigra | 1983 |
Naloxone blocks the effect of 5-hydroxy-tryptophan on passive avoidance learning in rats: implication of endogenous opiod peptides.
Topics: 5-Hydroxytryptophan; Animals; Avoidance Learning; Behavior, Animal; Clorgyline; Endorphins; Enkephalin, Methionine; Enkephalins; Male; Naloxone; Rats; Serotonin | 1981 |
Effects of intraventricular morphine and enkephalins on locomotor activity in nondependent, morphine-dependent and postdependent rats.
Topics: Animals; Dose-Response Relationship, Drug; Endorphins; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Enkephalins; Humans; Male; Morphine; Morphine Dependence; Motor Activity; Naloxone; Rats; Time Factors | 1981 |
The behavioural effects of enkephalin analogues injected into the ventral tegmental area and globus pallidus.
Topics: Animals; Behavior, Animal; Endorphins; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Enkephalins; Flupenthixol; Globus Pallidus; Male; Motor Activity; Naloxone; Organ Specificity; Rats; Tegmentum Mesencephali | 1981 |
Opiate alkaloids antagonize postsynaptic glycine and GABA responses: correlation with convulsant action.
Topics: Animals; Cells, Cultured; Dextrorphan; Enkephalin, Methionine; Enkephalins; Evoked Potentials; gamma-Aminobutyric Acid; Glycine; Levorphanol; Mice; Morphine; Naloxone; Narcotics; Neural Inhibition; Neurons; Seizures; Spinal Cord; Synapses | 1982 |
Reward produced by microinjection of (D-Ala2),Met5-enkephalinamide into the ventral tegmental area.
Topics: Animals; Conditioning, Operant; Endorphins; Enkephalin, Methionine; Enkephalins; Male; Naloxone; Rats; Reward; Tegmentum Mesencephali | 1982 |
Contraversive circling and facilitation of the perioral biting reflex by injection of substance P or D-Ala2-Met-encephalinamide into the substantia nigra.
Topics: Animals; Appetitive Behavior; Dominance, Cerebral; Endorphins; Enkephalin, Methionine; Enkephalins; Humans; Male; Muscimol; Naloxone; Predatory Behavior; Rats; Rats, Inbred Strains; Reflex; Stereotyped Behavior; Substantia Nigra | 1982 |
Spreading depression induced by microinjection of enkephalins into the hippocampus and neocortex.
Topics: Animals; Cerebral Cortex; Cortical Spreading Depression; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; Hippocampus; Male; Membrane Potentials; Naloxone; Rats | 1981 |
Morphine and delta-opiate agonists locally stimulate in vivo dopamine release in cat caudate nucleus.
Topics: Animals; Cats; Caudate Nucleus; Dopamine; Endorphins; Enkephalin, Methionine; Enkephalins; Morphine; Naloxone | 1981 |
Enhanced analgesic activity of liposomised Met-enkephalin analogue.
Topics: Analgesia; Animals; Endorphins; Enkephalin, Methionine; Enkephalins; Liposomes; Mice; Naloxone | 1981 |
Naloxone-reversible effects of d-Ala2-Met5-enkephalinamide-induced behavioral activity in rats.
Topics: Animals; Behavior, Animal; Dose-Response Relationship, Drug; Enkephalin, Methionine; Enkephalins; Male; Morphine; Motor Activity; Naloxone; Rats | 1980 |
Peripheral excitatory effects of two enkephalinase inhibitors, acetorphan and thiorphan, and an enkephalin analogue, [D-Ala2-Met5]-enkephalinamide, on uterine motility in periparturient rats in vivo and in vitro.
Topics: Animals; Dose-Response Relationship, Drug; Enkephalin, Methionine; Female; Naloxone; Narcotic Antagonists; Neprilysin; Neurotransmitter Agents; Pregnancy; Protease Inhibitors; Rats; Rats, Wistar; Stimulation, Chemical; Thiorphan; Uterine Contraction | 1995 |
Schistosoma mansoni: an enkephalinergic system that may participate in internal and host-parasite signaling.
Topics: Animals; beta-Endorphin; Binding, Competitive; Biomphalaria; Cell Communication; Cricetinae; Enkephalin, Methionine; Enkephalins; Host-Parasite Interactions; Naloxone; Radioimmunoassay; Receptors, Opioid; Schistosoma mansoni; Signal Transduction; Trypsin; Trypsin Inhibitors | 1993 |
Naltrindole sensitive delta 2 opioid receptor mediates invertebrate immunocyte activation.
Topics: Animals; Bivalvia; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Enkephalins; Humans; Immune System; Naloxone; Naltrexone; Narcotic Antagonists; Receptors, Opioid, delta | 1995 |
Central and peripheral involvement of endogenous opioid peptides in gastric protection in stressed rats.
Topics: Analysis of Variance; Animals; Cold Temperature; Enkephalin, Methionine; Gastric Mucosa; Injections, Intraperitoneal; Injections, Intraventricular; Injections, Subcutaneous; Male; Naloxone; Narcotic Antagonists; Protease Inhibitors; Quaternary Ammonium Compounds; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Stress, Physiological; Thiorphan | 1996 |
Inhibitory role of opioid peptides in the regulation of aggressive and sexual behaviors in male Japanese quails.
Topics: Aggression; Animals; Behavior, Animal; Coturnix; Drinking; Eating; Enkephalin, Methionine; Hypothalamus; Male; Naloxone; Narcotic Antagonists; Preoptic Area; Receptors, Opioid, delta; Sexual Behavior, Animal | 1997 |
Possible involvement of the serotonergic system in intraseptal opioid-induced hypothermia in ground squirrels.
Topics: Animals; Body Temperature; Body Temperature Regulation; Cyproheptadine; Enkephalin, Methionine; Female; Hydroxyindoleacetic Acid; Male; Naloxone; Sciuridae; Septum Pellucidum; Serotonin; Serotonin Antagonists | 1997 |
Role of midbrain ventro-lateral tegmental area (VTA) enkephalinergic mechanisms in the facilitation of hypothalamically-induced predatory attack behaviour.
Topics: Animals; Cats; Drug Interactions; Electric Stimulation; Electrodes, Implanted; Enkephalin, Methionine; Enkephalins; Female; Hypothalamus; Male; Microinjections; Naloxone; Narcotic Antagonists; Predatory Behavior; Rats; Staining and Labeling; Ventral Tegmental Area | 1997 |
Enhanced hemodynamic response to [D-ALA2,D-MET5]-methionine enkephalin (DAME) in streptozotocin-induced diabetic rats is reversed by insulin replacement.
Topics: Animals; Blood Flow Velocity; Blood Glucose; Blood Pressure; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Enkephalin, Methionine; Ganglionic Blockers; Hexamethonium; Hindlimb; Insulin; Male; Naloxone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Vascular Resistance | 1998 |
Effects of peptidase inhibitors, [D-Ala2, Met5]-enkephalinamide and antiserum to methionine-enkephalin microinjected into the caudal periaqueductal gray on morphine withdrawal in rats.
Topics: Animals; Enkephalin, Methionine; Enkephalins; Immune Sera; Male; Microinjections; Morphine; Morphine Dependence; Naloxone; Periaqueductal Gray; Protease Inhibitors; Protein Precursors; Rats; Rats, Sprague-Dawley; RNA, Messenger; Substance Withdrawal Syndrome | 1998 |
The opioid peptide analog D-Ala2-Met-enkephalinamide decreases bile flow by a central mechanism.
Topics: Animals; Bile; Blood Pressure; Cholestasis; Cholinergic Antagonists; Enkephalin, Methionine; Gallbladder; Male; Naloxone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley | 1999 |
Rostral ventrolateral medulla opioid receptor activation modulates glutamate release and attenuates the exercise pressor reflex.
Topics: Animals; Blood Pressure; Enkephalin, Methionine; Female; Glutamic Acid; Heart Rate; Male; Medulla Oblongata; Muscle Contraction; Naloxone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Opioid | 2000 |
Effects of opioid receptor activation on cardiovascular responses and extracellular monoamines within the rostral ventrolateral medulla during static contraction of skeletal muscle.
Topics: Animals; Blood Pressure; Dopamine; Enkephalin, Methionine; Extracellular Space; Female; Glutamic Acid; Heart Rate; Medulla Oblongata; Microdialysis; Muscle Contraction; Naloxone; Narcotic Antagonists; Norepinephrine; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Serotonin | 2001 |
GABA-opioid interactions in the globus pallidus: [D-Ala2]-Met-enkephalinamide attenuates potassium-evoked GABA release after nigrostriatal lesion.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Behavior, Animal; Cats; Disease Models, Animal; Enkephalin, Methionine; Extracellular Space; gamma-Aminobutyric Acid; Globus Pallidus; Male; Microdialysis; Naloxone; Narcotic Antagonists; Parkinsonian Disorders; Potassium; Recovery of Function | 2002 |
Opioids in the hypothalamus control dopamine and acetylcholine levels in the nucleus accumbens.
Topics: 3,4-Dihydroxyphenylacetic Acid; Acetylcholine; Analgesics, Opioid; Animals; Dopamine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Methionine; Homovanillic Acid; Male; Microdialysis; Microinjections; Morphine; Naloxone; Narcotic Antagonists; Neural Pathways; Nucleus Accumbens; Paraventricular Hypothalamic Nucleus; Rats; Rats, Sprague-Dawley | 2010 |
Opioids in the hypothalamic paraventricular nucleus stimulate ethanol intake.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Alcohol Drinking; Analgesics, Opioid; Animals; Central Nervous System Depressants; Drinking; Eating; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Methionine; Ethanol; Male; Microinjections; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Paraventricular Hypothalamic Nucleus; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Stimulation, Chemical | 2010 |
Opioids in the perifornical lateral hypothalamus suppress ethanol drinking.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Alcohol Drinking; Analgesics, Opioid; Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Methionine; Hypothalamus; Naloxone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Opioid | 2013 |