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enkephalinamide-met, ala(2)- and morphine

enkephalinamide-met, ala(2)- has been researched along with morphine in 73 studies

Research

Studies (73)

TimeframeStudies, this research(%)All Research%
pre-199065 (89.04)18.7374
1990's6 (8.22)18.2507
2000's0 (0.00)29.6817
2010's2 (2.74)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
del Río, J; Garzón, J; Moratalla, R1
deCosta, B; Jiang, Q; Porreca, F; Rice, KC1
Frank, C; Proietti, ML; Sagratella, S; Scotti De Carolis, A; Trampus, M1
Ahokas, RA; Blatteis, CM; Llanos-Q, J; Mashburn, TA; Seydoux, J1
Inoki, R; Shibutani, T; Tsai, HY; Yonehara, N1
Finesso, M; Gorio, A; Prosdocimi, M1
Burks, TF; Gehrig, CA; Hruby, VJ; Lemcke, PK; Shook, JE1
Makimura, M; Murakoshi, Y1
Dhawan, BN; Dhotre, BJ; Mathur, KB; Patnaik, GK; Raghubir, R; Sharma, SD1
Blancquaert, JP; Lefebvre, RA; Willems, JL1
Baker, BI; Bird, DJ; Buckingham, JC; Mukherjee, S1
Groppetti, A; Parenti, M; Tirone, F; Viganó, A1
Deguchi, T; Yokoyama, E1
Crema, G; Giagnoni, G; Gori, E; Parolaro, D; Sala, M; Santagostino, A1
Bradford, HF; Crowder, JM; Norris, DK1
Inoki, R; Kudo, T; Ohkubo, T; Shibata, M; Takahashi, H1
Assanah, P; Ford, R; Harper, J; Jackson, DM; Leung, MK; Stefano, GB; Tetrault, L; Torres, JC1
Bucarelli, A; De Montis, MG; Devoto, P; Tagliamonte, A1
Biondi, C; Borasio, PG; Capuzzo, A; Ferretti, ME1
Coscia, CJ; Devane, WA; Howlett, AC; Spain, JW1
Greenspan, DL; Musacchio, JM1
Dzoljic, MR; Elliott, GR; van Batenburg, MJ1
Lanthier, D; Leibowitz, SF; Stanley, BG1
Del Rio, J; Fernandez-Tome, MP; Gonzalez, Y1
Schwartz, JP1
Jourdan, ML; Lee, TF; Wang, LC1
Bentley, AM; Wallis, M1
Chan, YS; Cheung, YM; Hwang, JC; Poon, PW; Wong, CL; Wong, TM1
Matsui, H; Yamamoto, C1
Bardon, T; Pairet, M; Ruckebusch, Y1
De Ceballos, ML; De Felipe, C1
Groves, PM; Ling, N; Nakamura, S; Tepper, JM; Young, SJ1
Chan, SK; Iwamoto, ET; Kiritsy-Roy, JA1
Gaginella, TS; Wu, ZC1
Fields, HL; Hentall, ID1
Groppetti, A; Olgiati, VR; Parenti, M; Tirone, F1
Galetta, S; Ling, GS; Pasternak, GW1
Huidobro, F; Huidobro-Toro, JP1
Huidobro-Toro, JP; Way, EL1
Byrne, WL; Codd, EE1
Pasternak, GW; Wolozin, BL1
Cowan, A; Tortella, FC1
Bernardini, GL; Clark, WG2
Adames, C; Fearon, Z; Guerrero-Muñoz, F; Way, EL1
Dewey, WL; Fu, TC; Jones, D; Martin, BR; Ohlsson, AE1
Krieger, AJ; Sapru, HN; Willette, RN1
Chesselet, MF; Glowinski, J; Lubetzki, C1
Baram, D; Levy, R; Simantov, R1
Kameyama, T; Ukai, M1
Frenk, H; Mayer, DJ; Watkins, LR1
Frenk, H; Mayer, DJ; Miller, J; Watkins, LR2
Brown, DR; Miller, RJ1
Fujita, N; Inoki, R; Nakahiro, M; Saito, K1
Kinscheck, IB; Mayer, DJ; Watkins, LR1
Peets, JM; Pomeranz, B; Power, C1
de Groat, WC; Hisamitsu, T1
Algeri, S; De Simoni, MG; Plaznik, A1
Balderrama, N; Maldonado, H; Miralto, A; Núñez, J1
Chéramy, A; Chesselet, MF; Desban, M; Glowinski, J; Lubetzki, C; Reisine, TD1
Algeri, S; De Simoni, MG; Guardabasso, V; Misterek, K1
Brady, LS; Holtzman, SG2
Macdonald, RL; Werz, MA1
Chéramy, A; Chesselet, MF; Glowinski, J; Reisine, TD1
Coy, DH; Dunlap, WP; Harston, CT; Spirtes, MA1
Fascher, E; Pryor, SC1
Chakrabarti, S; Law, PY; Loh, HH1
Bilfinger, TV; Fimiani, C; Mattocks, D; Rialas, CM; Salzet, M; Stefano, GB1
Fukunaga, Y; Inoue, N; Kishioka, S; Miyamoto, M; Yamamoto, H1
Barson, JR; Hoebel, BG; Leibowitz, SF; Rada, P1
Barson, JR; Carr, AJ; Hoebel, BG; Leibowitz, SF; Rada, P; Sobhani, NC; Soun, JE1

Other Studies

73 other study(ies) available for enkephalinamide-met, ala(2)- and morphine

ArticleYear
[Monoaminergic modulation of the analgesia induced in rats by (D-Ala2)-met-enkephalinamide (DADA)].
    Archivos de farmacologia y toxicologia, 1979, Volume: 5, Issue:3

    Topics: Analgesics; Animals; Biogenic Amines; Drug Interactions; Endorphins; Enkephalin, Methionine; Enkephalins; Male; Monoamine Oxidase Inhibitors; Morphine; Rats

1979
Effects of oxymorphindole on morphine induced-antinociception in mice and rats.
    NIDA research monograph, 1990, Volume: 105

    Topics: Analgesics; Animals; Dose-Response Relationship, Drug; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; Mice; Morphine; Morpholines; Rats; Receptors, Opioid; Receptors, Opioid, delta

1990
An in vitro study on the hippocampal epileptogenic properties of enkephalins and enkephalinase inhibitors in rats.
    General pharmacology, 1991, Volume: 22, Issue:4

    Topics: Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Methionine; Enkephalins; Epilepsy; Hippocampus; In Vitro Techniques; Male; Morphine; Neprilysin; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, mu

1991
Hypothalamic opioids and the acute-phase glycoprotein response in guinea pigs.
    Brain research bulletin, 1985, Volume: 15, Issue:6

    Topics: Acute-Phase Proteins; Animals; Blood Proteins; Dynorphins; Endorphins; Enkephalin, Methionine; Fever; Glycoproteins; Guinea Pigs; Hypothalamus; Interleukin-1; Lipopolysaccharides; Male; Morphine; Temperature; Time Factors

1985
Effects of opioids and opioid peptide on the release of substance P-like material induced by tooth pulp stimulation in the trigeminal nucleus caudalis of the rabbit.
    European journal of pharmacology, 1986, Oct-07, Volume: 129, Issue:3

    Topics: Animals; Dental Pulp; Electric Stimulation; Enkephalin, Methionine; Male; Morphine; Naloxone; Pain; Rabbits; Substance P; Trigeminal Nuclei

1986
Enkephalin modulation of neural transmission in the cat stellate ganglion: pharmacological actions of exogenous opiates.
    Journal of the autonomic nervous system, 1986, Volume: 17, Issue:3

    Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Cats; Dimethylphenylpiperazinium Iodide; Electric Stimulation; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; Female; Ganglia, Sympathetic; Heart Rate; Histamine; Male; Morphine; Synaptic Transmission

1986
Antidiarrheal properties of supraspinal mu and delta and peripheral mu, delta and kappa opioid receptors: inhibition of diarrhea without constipation.
    The Journal of pharmacology and experimental therapeutics, 1989, Volume: 249, Issue:1

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Antidiarrheals; Constipation; Dose-Response Relationship, Drug; Endorphins; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Methionine; Enkephalins; Gastrointestinal Motility; Injections, Intraventricular; Male; Mice; Mice, Inbred ICR; Morphine; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu

1989
Kappa-opioid agonists do not inhibit adenylate cyclase.
    Journal of pharmacobio-dynamics, 1989, Volume: 12, Issue:3

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adenylyl Cyclase Inhibitors; Animals; Benzeneacetamides; Benzomorphans; Binding, Competitive; Brain; Cell Membrane; Enkephalin, Methionine; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Levorphanol; Morphine; Naloxone; Pentazocine; Pyrrolidines; Rana catesbeiana; Receptors, Opioid; Receptors, Opioid, kappa; Sodium Chloride

1989
Morphine-like activity of substituted amides & imides of [D-Ala2, Met5]-enkephalin.
    The Indian journal of medical research, 1989, Volume: 90

    Topics: Amides; Enkephalin, Methionine; Imides; Morphine; Pain Measurement; Structure-Activity Relationship

1989
Antiaversive properties of opioids in the conditioned taste aversion test in the rat.
    Pharmacology, biochemistry, and behavior, 1987, Volume: 27, Issue:3

    Topics: Animals; Avoidance Learning; Conditioning, Classical; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Female; Fentanyl; Male; Methadone; Morphine; Narcotics; Rats; Rats, Inbred Strains; Receptors, Opioid; Taste

1987
Hypothalamo-pituitary-interrenal responses to opioid substances in the trout. II. Effects of morphine and D-Ala2, Met5-enkephalinamide on plasma cortisol titres in vivo.
    General and comparative endocrinology, 1987, Volume: 68, Issue:1

    Topics: Adrenocorticotropic Hormone; Aging; Animals; Corticotropin-Releasing Hormone; Enkephalin, Methionine; Hydrocortisone; Hypothalamus; Interrenal Gland; Morphine; Naloxone; Pituitary Gland, Anterior; Salmonidae; Time Factors; Trout

1987
Effects of the desensitization by morphine of the opiate-dependent adenylate cyclase system in the rat striatum on the activity of the inhibitory regulatory G protein.
    Biochemical pharmacology, 1988, Mar-15, Volume: 37, Issue:6

    Topics: Adenylyl Cyclases; Animals; Corpus Striatum; Enkephalin, Methionine; GTP Phosphohydrolases; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Male; Morphine; Rats; Rats, Inbred Strains; Receptors, Opioid; Thionucleotides

1988
Monoclonal antibody to enkephalins with binding characteristics similar to opiate receptor.
    Biochemical and biophysical research communications, 1985, Jan-16, Volume: 126, Issue:1

    Topics: alpha-Endorphin; Animals; Antibodies, Monoclonal; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Enkephalins; Mice; Morphine; Naloxone; Receptors, Opioid

1985
Intestinal effect and analgesia: evidence for different involvement of opioid receptor subtypes in periaqueductal gray matter.
    European journal of pharmacology, 1986, Jan-14, Volume: 120, Issue:1

    Topics: Analgesia; Animals; beta-Endorphin; D-Ala(2),MePhe(4),Met(0)-ol-enkephalin; Dynorphins; Endorphins; Enkephalin, Methionine; Female; Gastrointestinal Motility; Injections; Male; Morphine; Muscle, Smooth; Periaqueductal Gray; Rats; Rats, Inbred Strains; Receptors, Opioid

1986
Morphine inhibition of calcium fluxes, neurotransmitter release and protein and lipid phosphorylation in brain slices and synaptosomes.
    Biochemical pharmacology, 1986, Aug-01, Volume: 35, Issue:15

    Topics: Adenylyl Cyclase Inhibitors; Amino Acids; Animals; Brain; Calcium; Cyclic AMP; Enkephalin, Methionine; Female; Guanosine Triphosphate; In Vitro Techniques; Lipid Metabolism; Morphine; Nerve Tissue Proteins; Neurotransmitter Agents; Phosphorylation; Rats; Rats, Inbred Strains; Synaptosomes

1986
[Peripheral analgesic actions of opioid peptides and morphine analogues].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1986, Volume: 88, Issue:2

    Topics: Analgesics, Opioid; Animals; Cyclazocine; Dynorphins; Enkephalin, Methionine; Ethylketocyclazocine; Levallorphan; Lidocaine; Male; Mice; Morphine; Naloxone; Pain; Peptide Fragments

1986
A behavioral role for enkephalins in regulating locomotor activity in the insect Leucophaea maderae: evidence for high affinity kappa-like opioid binding sites.
    Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1986, Volume: 85, Issue:1

    Topics: Animals; Enkephalin, Methionine; Enkephalins; Morphine; Motor Activity; Orthoptera; Receptors, Opioid; Receptors, Opioid, kappa

1986
Opioid activity of lefetamine.
    Pharmacological research communications, 1985, Volume: 17, Issue:5

    Topics: Anesthetics, Local; Animals; Binding, Competitive; Brain; Cyclazocine; Enkephalin, Methionine; Ethylketocyclazocine; Lethal Dose 50; Male; Methadone; Mice; Morphine; Naloxone; Phenethylamines; Rats; Rats, Inbred Strains; Reaction Time; Receptors, Opioid

1985
[Opiate regulation of cyclic AMP levels in sympathetic ganglia in mammals].
    Bollettino della Societa italiana di biologia sperimentale, 1985, Aug-30, Volume: 61, Issue:8

    Topics: Animals; Cyclic AMP; Dinoprostone; Enkephalin, Methionine; Ganglia, Sympathetic; Guinea Pigs; Morphine; Naloxone; Narcotics; Prostaglandins E; Rabbits; Rats; Rats, Inbred Strains

1985
An assessment of the role of opioid receptors in the response to cannabimimetic drugs.
    Journal of neurochemistry, 1986, Volume: 46, Issue:6

    Topics: Adenylyl Cyclase Inhibitors; Animals; Cannabinoids; Cell Line; Dronabinol; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Etorphine; Morphine; Naltrexone; Neuroblastoma; Neurons; Receptors, Opioid; Receptors, Opioid, delta

1986
The adenylate cyclase rebound response to naloxone in the NG108-15 cells. Effects of etorphine and other opiates.
    Neuropharmacology, 1986, Volume: 25, Issue:8

    Topics: Adenylyl Cyclases; Alprostadil; Cell Line; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Etorphine; Glioma; Morphinans; Morphine; Naloxone; Neuroblastoma; Receptors, Opioid

1986
Enhanced prostaglandin E2 and thromboxane B2 release from resident peritoneal macrophages isolated from morphine-dependent rats.
    FEBS letters, 1987, Jun-08, Volume: 217, Issue:1

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Arachidonic Acids; Cells, Cultured; Cyclic AMP; Dinoprostone; Enkephalin, Methionine; Glucuronidase; L-Lactate Dehydrogenase; Macrophages; Male; Morphine; Morphine Dependence; Peritoneal Cavity; Prostaglandins E; Rats; Rats, Inbred Strains; Thromboxane B2

1987
Multiple brain sites sensitive to feeding stimulation by opioid agonists: a cannula-mapping study.
    Pharmacology, biochemistry, and behavior, 1988, Volume: 31, Issue:4

    Topics: Animals; Benzomorphans; Brain; Brain Mapping; Dose-Response Relationship, Drug; Enkephalin, Methionine; Feeding Behavior; Male; Morphinans; Morphine; Rats; Rats, Inbred Strains; Time Factors

1988
Interaction between opioid agonists or naloxone and 5-HTP on feeding behavior in food-deprived rats.
    Pharmacology, biochemistry, and behavior, 1988, Volume: 29, Issue:2

    Topics: 5-Hydroxytryptophan; Animals; D-Ala(2),MePhe(4),Met(0)-ol-enkephalin; Drug Interactions; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Feeding Behavior; Food Deprivation; Male; Morphine; Naloxone; Narcotics; Rats; Rats, Inbred Strains

1988
Chronic exposure to opiate agonists increases proenkephalin biosynthesis in NG108 cells.
    Brain research, 1988, Volume: 427, Issue:2

    Topics: Animals; Cell Line; Colforsin; Enkephalin, Methionine; Enkephalins; Etorphine; Genes; Glioma; Hybrid Cells; Morphinans; Morphine; Naloxone; Neuroblastoma; Protein Precursors; RNA, Messenger; Transcription, Genetic

1988
Seasonal difference in thermoregulatory responses to opiates in a mammalian hibernator.
    Pharmacology, biochemistry, and behavior, 1987, Volume: 26, Issue:3

    Topics: Animals; Body Temperature Regulation; Enkephalin, Methionine; Female; Hibernation; Injections, Intraventricular; Morphine; Naloxone; Oxygen Consumption; Sciuridae; Seasons

1987
Effects of two enkephalin analogues, morphine sulphate, dopamine and naloxone on prolactin secretion from rat anterior pituitary glands in vitro.
    The Journal of endocrinology, 1986, Volume: 109, Issue:3

    Topics: Animals; Depression, Chemical; Dopamine; Dose-Response Relationship, Drug; Enkephalin, Leucine; Enkephalin, Methionine; Female; Morphine; Naloxone; Narcotics; Organ Culture Techniques; Perfusion; Pituitary Gland, Anterior; Prolactin; Rats; Rats, Inbred Strains; Time Factors

1986
Effects of superfusion of morphine and enkephalins on the activity of single units in the spinal trigeminal nucleus and cuneate nucleus of cat.
    Methods and findings in experimental and clinical pharmacology, 1986, Volume: 8, Issue:6

    Topics: Action Potentials; Animals; Cats; Electrophysiology; Enkephalin, Methionine; Enkephalins; Female; Male; Medulla Oblongata; Morphine; Naloxone; Trigeminal Nucleus, Spinal

1986
Neuronal sensitivity to opiate and opioid peptides in the bed nucleus of the stria terminalis. Effects of chronic treatment with morphine.
    Neuropharmacology, 1984, Volume: 23, Issue:7A

    Topics: Amygdala; Animals; Dihydromorphine; Dose-Response Relationship, Drug; Drug Tolerance; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Evoked Potentials; Guinea Pigs; Hypothalamus, Middle; Male; Morphine; Neural Pathways; Neurons; Norepinephrine; Receptors, Opioid; Synaptic Transmission

1984
Opioid control of the ruminant stomach motility: functional importance of mu, kappa and delta receptors.
    Life sciences, 1984, Oct-22, Volume: 35, Issue:17

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Cyclazocine; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Ethylketocyclazocine; Fentanyl; Gastrointestinal Motility; Morphine; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Sheep; Stomach

1984
Circannual variation in opioid receptor sensitivity in mouse vas deferens.
    European journal of pharmacology, 1984, Oct-30, Volume: 106, Issue:1

    Topics: Animals; Circadian Rhythm; Electric Stimulation; Enkephalin, Methionine; In Vitro Techniques; Isometric Contraction; Male; Mice; Mice, Inbred ICR; Morphine; Receptors, Opioid; Seasons; Vas Deferens

1984
Noradrenergic terminal excitability: effects of opioids.
    Neuroscience letters, 1982, May-17, Volume: 30, Issue:1

    Topics: Animals; Dose-Response Relationship, Drug; Endorphins; Enkephalin, Methionine; Enkephalins; Frontal Lobe; Locus Coeruleus; Male; Morphine; Naloxone; Neurotransmitter Agents; Rats; Rats, Inbred Strains; Reaction Time; Receptors, Opioid

1982
Methionine oxidation enhances opioid activity of an enkephalin analog.
    Life sciences, 1983, Feb-21, Volume: 32, Issue:8

    Topics: Analgesics, Opioid; Animals; Enkephalin, Methionine; Male; Methionine; Microinjections; Morphine; Oxidation-Reduction; Rats; Rats, Inbred Strains; Structure-Activity Relationship

1983
[D-Ala2,D-Met5NH2]-enkephalin inhibits acetylcholine release from the submucosal plexus of rat colon.
    The Journal of pharmacy and pharmacology, 1983, Volume: 35, Issue:12

    Topics: Acetylcholine; Animals; Colon; Enkephalin, Methionine; In Vitro Techniques; Intestinal Mucosa; Morphine; Naloxone; Rats

1983
Actions of opiates, substance P, and serotonin on the excitability of primary afferent terminals and observations on interneuronal activity in the neonatal rat's dorsal horn in vitro.
    Neuroscience, 1983, Volume: 9, Issue:3

    Topics: Afferent Pathways; Animals; Culture Techniques; Dose-Response Relationship, Drug; Enkephalin, Methionine; Evoked Potentials; gamma-Aminobutyric Acid; Ganglia, Spinal; Interneurons; Morphine; Naloxone; Rats; Serotonin; Spinal Cord; Spinal Nerve Roots; Substance P; Synaptic Transmission

1983
Presence of opiate receptors on striatal serotoninergic nerve terminals.
    Brain research, 1983, Dec-05, Volume: 280, Issue:2

    Topics: Animals; Corpus Striatum; Dopamine; Enkephalin, Methionine; Fenfluramine; Hydroxyindoleacetic Acid; Male; Morphine; Naloxone; Nerve Degeneration; Neurons; Rats; Rats, Inbred Strains; Receptors, Opioid; Serotonin

1983
Oxymorphazone: a long-acting opiate analgesic.
    Cellular and molecular neurobiology, 1984, Volume: 4, Issue:1

    Topics: Analgesia; Animals; Brain; Dose-Response Relationship, Drug; Drug Tolerance; Enkephalin, Methionine; Hydromorphone; Injections, Intraventricular; Morphine; Naloxone; Oxymorphone; Rats; Receptors, Opioid; Time Factors

1984
Central effects of morphine, levorphanol, (-)-methadone and the opioid-like peptides beta-endorphin and D-alanine2- methionine enkephalinamide on urine volume outflow and electrolytes.
    The Journal of pharmacology and experimental therapeutics, 1981, Volume: 217, Issue:3

    Topics: Animals; beta-Endorphin; Brain; Diuresis; Electrolytes; Endorphins; Enkephalin, Methionine; Enkephalins; Female; Levorphanol; Male; Methadone; Morphine; Naloxone; Narcotics; Rats; Vasopressins

1981
Comparative study on the effect of morphine and the opioid-like peptides in the vas deferens of rodents: species and strain differences, evidence for multiple opiate receptors.
    Life sciences, 1981, Mar-23, Volume: 28, Issue:12

    Topics: Animals; beta-Endorphin; Endorphins; Enkephalin, Methionine; Enkephalins; Guinea Pigs; Male; Mice; Mice, Inbred ICR; Morphine; Morphine Derivatives; Peptides; Rats; Receptors, Opioid; Species Specificity; Vas Deferens

1981
Seasonal variation in the apparent number of binding sites for 3H-opioid agonists and antagonists.
    Life sciences, 1981, Jun-08, Volume: 28, Issue:23

    Topics: Animals; Binding Sites; Brain; Dihydromorphine; Endorphins; Enkephalin, Methionine; Enkephalins; Female; Kinetics; Male; Mice; Morphinans; Morphine; Naloxone; Naltrexone; Receptors, Opioid; Seasons

1981
Classification of multiple morphine and enkephalin binding sites in the central nervous system.
    Proceedings of the National Academy of Sciences of the United States of America, 1981, Volume: 78, Issue:10

    Topics: Animals; Binding, Competitive; Brain; Cell Membrane; Endorphins; Enkephalin, Methionine; Enkephalins; Kinetics; Morphine; Naloxone; Rats; Receptors, Opioid; Structure-Activity Relationship

1981
A quantitative analysis of the shaking behavior induced in rats by beta-endorphin and [D-Ala2, Met5]enkephalinamide.
    Life sciences, 1982, Jan-11, Volume: 30, Issue:2

    Topics: Animals; Behavior, Animal; beta-Endorphin; Dose-Response Relationship, Drug; Drug Tolerance; Endorphins; Enkephalin, Methionine; Enkephalins; Male; Morphine; Naloxone; Rats; Rats, Inbred Strains

1982
Morphine-induced hyperthermia: lack of cross-tolerance with enkephalin analogs.
    Brain research, 1982, Jan-07, Volume: 231, Issue:1

    Topics: Animals; Body Temperature Regulation; Cats; D-Ala(2),MePhe(4),Met(0)-ol-enkephalin; Dose-Response Relationship, Drug; Drug Tolerance; Endorphins; Enkephalin, Methionine; Enkephalins; Morphine; Naloxone; Pentazocine; Receptors, Opioid

1982
Calcium-opiate antagonism in the periaqueductal grey (PGA) region.
    European journal of pharmacology, 1981, Dec-17, Volume: 76, Issue:4

    Topics: Animals; beta-Endorphin; Calcium; Cerebral Aqueduct; Endorphins; Enkephalin, Methionine; Enkephalins; Male; Morphine; Nociceptors; Rats; Rats, Inbred Strains

1981
Distribution of radioactivity in the spinal cord after intracerebroventricular and intravenous injection of radiolabeled opioid peptides in mice.
    The Journal of pharmacology and experimental therapeutics, 1982, Volume: 221, Issue:2

    Topics: Analgesics; Animals; beta-Endorphin; Brain; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; Injections, Intravenous; Injections, Intraventricular; Male; Mice; Mice, Inbred ICR; Morphine; Muscles; Spinal Cord

1982
Opioids increase laryngeal resistance and motoneuron activity in the recurrent laryngeal nerve.
    European journal of pharmacology, 1982, May-07, Volume: 80, Issue:1

    Topics: Animals; Biguanides; Chemoreceptor Cells; Endorphins; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Enkephalins; Laryngeal Nerves; Larynx; Male; Morphine; Motor Neurons; Rats; Receptors, Opioid; Recurrent Laryngeal Nerve; Reflex

1982
Modulation of dopamine release in rat striatal slices by delta opiate agonists.
    The Journal of pharmacology and experimental therapeutics, 1982, Volume: 222, Issue:2

    Topics: Animals; Corpus Striatum; Dopamine; Endorphins; Enkephalin, Methionine; Enkephalins; In Vitro Techniques; Male; Morphine; Naloxone; Narcotics; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Tetrodotoxin

1982
Down regulation of enkephalin (delta) receptors. Demonstration in membrane-bound and solubilized receptors.
    Biochimica et biophysica acta, 1982, Dec-30, Volume: 721, Issue:4

    Topics: Alkaloids; Animals; Drug Tolerance; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; Etorphine; Glioma; Hybrid Cells; In Vitro Techniques; Morphine; Neuroblastoma; Rats; Receptors, Opioid; Solubility

1982
Multi-dimensional analyses of behavior in mice treated with morphine, endorphins and [des-tyrosine1]-gamma-endorphin.
    Pharmacology, biochemistry, and behavior, 1983, Volume: 19, Issue:4

    Topics: Animals; Behavior, Animal; beta-Endorphin; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Injections, Intraventricular; Male; Mice; Morphine; Naltrexone; Peptide Fragments

1983
Differential behavioral effects induced by intrathecal microinjection of opiates: comparison of convulsive and cataleptic effects produced by morphine, methadone, and D-Ala2-methionine-enkephalinamide.
    Brain research, 1984, May-07, Volume: 299, Issue:1

    Topics: Animals; Arousal; Behavior, Animal; Cerebral Cortex; Dose-Response Relationship, Drug; Electroencephalography; Enkephalin, Methionine; Evoked Potentials; Injections, Spinal; Male; Methadone; Morphine; Motor Activity; Pentylenetetrazole; Rats; Rats, Inbred Strains; Receptors, Opioid; Seizures; Spinal Cord

1984
Cataleptic effects of opiates following intrathecal administration.
    Brain research, 1984, May-07, Volume: 299, Issue:1

    Topics: Animals; Arousal; Dose-Response Relationship, Drug; Enkephalin, Methionine; Hindlimb; Injections, Spinal; Male; Methadone; Morphine; Motor Activity; Rats; Rats, Inbred Strains; Reaction Time; Receptors, Opioid; Spinal Cord

1984
Nonspecific convulsions are induced by morphine but not D-Ala2-methionine-enkephalinamide at cortical sites.
    Brain research, 1984, May-07, Volume: 299, Issue:1

    Topics: Animals; Cerebral Cortex; Drug Tolerance; Electroencephalography; Enkephalin, Methionine; Evoked Potentials; Injections, Intraventricular; Male; Methadone; Morphine; Naltrexone; Rats; Rats, Inbred Strains; Receptors, Opioid; Seizures

1984
Adrenergic mediation of the intestinal antisecretory action of opiates administered into the central nervous system.
    The Journal of pharmacology and experimental therapeutics, 1984, Volume: 231, Issue:1

    Topics: Animals; Blood Pressure; Brain; Cholera Toxin; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Enkephalins; Hydrogen-Ion Concentration; In Vitro Techniques; Injections, Intraventricular; Intestinal Mucosa; Male; Morphine; Rats; Rats, Inbred Strains; Sympathetic Nervous System; Tyramine

1984
Effects of morphine and (D-Ala, Met)-enkephalinamide on 45Ca-uptake to rat brain striatal slices.
    Neuropeptides, 1984, Volume: 5, Issue:1-3

    Topics: Animals; Biological Transport, Active; Calcium; Corpus Striatum; Enkephalin, Methionine; In Vitro Techniques; Morphine; Potassium; Rats

1984
Potentiation of opiate analgesia and apparent reversal of morphine tolerance by proglumide.
    Science (New York, N.Y.), 1984, Apr-27, Volume: 224, Issue:4647

    Topics: Analgesia; Animals; Brain; Dose-Response Relationship, Drug; Drug Synergism; Drug Tolerance; Endorphins; Enkephalin, Methionine; Glutamine; Humans; Injections, Spinal; Morphine; Proglumide; Rats; Spinal Cord

1984
Long latency spinal cord dorsum potential; suppression by intrathecal morphine and enkephalin analog.
    Brain research, 1984, Jun-25, Volume: 304, Issue:2

    Topics: Analgesics; Animals; Disease Models, Animal; Drug Evaluation, Preclinical; Enkephalin, Methionine; Evoked Potentials; Injections, Spinal; Male; Morphine; Pain; Rats; Rats, Inbred Strains; Spinal Cord

1984
The inhibitory effect of opioid peptides and morphine applied intrathecally and intracerebroventricularly on the micturition reflex in the cat.
    Brain research, 1984, Apr-23, Volume: 298, Issue:1

    Topics: Animals; Cats; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Enkephalins; Female; Morphine; Naloxone; Oligopeptides; Reflex; Thiorphan; Tiopronin; Urination

1984
The effect of opiate treatment on the postdecapitation reflex and monoamine metabolism in the rat spinal cord.
    Pharmacology, biochemistry, and behavior, 1983, Volume: 19, Issue:3

    Topics: Animals; Biogenic Amines; Dopamine; Enkephalin, Methionine; Injections, Intraventricular; Male; Morphine; Rats; Reflex; Serotonin; Spinal Cord

1983
The stinging response of the honeybee: effects of morphine, naloxone and some opioid peptides.
    Pharmacology, biochemistry, and behavior, 1983, Volume: 19, Issue:16

    Topics: Animals; Bees; Behavior, Animal; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Insect Bites and Stings; Morphine; Naloxone

1983
Local and distal effects induced by unilateral striatal application of opiates in the absence or in the presence of naloxone on the release of dopamine in both caudate nuclei and substantiae nigrae of the cat.
    Brain research, 1983, Jan-10, Volume: 258, Issue:2

    Topics: Animals; Cats; Caudate Nucleus; Corpus Striatum; Dopamine; Enkephalin, Methionine; Female; Fentanyl; Functional Laterality; Male; Morphine; Naloxone; Narcotics; Structure-Activity Relationship; Substantia Nigra

1983
Similarities and differences between D-ALA2 MET5 enkephalin amide and morphine in the induction of tolerance to their effects on catalepsy and on dopamine metabolism in the rat brain.
    Naunyn-Schmiedeberg's archives of pharmacology, 1982, Volume: 321, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Catalepsy; Corpus Striatum; Dopamine; Drug Tolerance; Enkephalin, Methionine; Humans; Limbic System; Male; Morphine; Rats; Substantia Nigra

1982
Effects of intraventricular morphine and enkephalins on locomotor activity in nondependent, morphine-dependent and postdependent rats.
    The Journal of pharmacology and experimental therapeutics, 1981, Volume: 218, Issue:3

    Topics: Animals; Dose-Response Relationship, Drug; Endorphins; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Enkephalins; Humans; Male; Morphine; Morphine Dependence; Motor Activity; Naloxone; Rats; Time Factors

1981
Depression of learned thermoregulatory behavior by central injection of opioids in cats.
    Pharmacology, biochemistry, and behavior, 1982, Volume: 16, Issue:6

    Topics: Animals; Avoidance Learning; Body Temperature Regulation; Cats; Conditioning, Operant; Endorphins; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Enkephalins; Injections, Intraventricular; Morphine; Motor Activity; Pentazocine

1982
Opiate alkaloids antagonize postsynaptic glycine and GABA responses: correlation with convulsant action.
    Brain research, 1982, Mar-18, Volume: 236, Issue:1

    Topics: Animals; Cells, Cultured; Dextrorphan; Enkephalin, Methionine; Enkephalins; Evoked Potentials; gamma-Aminobutyric Acid; Glycine; Levorphanol; Mice; Morphine; Naloxone; Narcotics; Neural Inhibition; Neurons; Seizures; Spinal Cord; Synapses

1982
Effects of intraventricular morphine and enkephalins on schedule-controlled behavior in nondependent, morphine-dependent and postdependent rats.
    The Journal of pharmacology and experimental therapeutics, 1981, Volume: 219, Issue:2

    Topics: Animals; Conditioning, Operant; Dose-Response Relationship, Drug; Endorphins; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Enkephalins; Humans; Injections, Intraventricular; Male; Morphine; Morphine Dependence; Rats; Rats, Inbred Strains; Substance Withdrawal Syndrome

1981
Morphine and delta-opiate agonists locally stimulate in vivo dopamine release in cat caudate nucleus.
    Nature, 1981, May-28, Volume: 291, Issue:5813

    Topics: Animals; Cats; Caudate Nucleus; Dopamine; Endorphins; Enkephalin, Methionine; Enkephalins; Morphine; Naloxone

1981
Naloxone-reversible effects of d-Ala2-Met5-enkephalinamide-induced behavioral activity in rats.
    Behavioral and neural biology, 1980, Volume: 30, Issue:1

    Topics: Animals; Behavior, Animal; Dose-Response Relationship, Drug; Enkephalin, Methionine; Enkephalins; Male; Morphine; Motor Activity; Naloxone; Rats

1980
The effects of opiates and opioid neuropeptides on mosquito hemocytes.
    Acta biologica Hungarica, 1995, Volume: 46, Issue:2-4

    Topics: Animals; Cell Size; Culex; Enkephalin, Methionine; Glycopeptides; Hemocytes; In Vitro Techniques; Morphine; Narcotics; Neprilysin; Opioid Peptides; Protease Inhibitors

1995
Distinct differences between morphine- and [D-Ala2,N-MePhe4,Gly-ol5]-enkephalin-mu-opioid receptor complexes demonstrated by cyclic AMP-dependent protein kinase phosphorylation.
    Journal of neurochemistry, 1998, Volume: 71, Issue:1

    Topics: Analgesics, Opioid; Antibody Specificity; Carbazoles; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Enkephalins; Enzyme Inhibitors; Indoles; Morphine; Neuroblastoma; Neurons; Phosphorylation; Precipitin Tests; Pyrroles; Receptors, Opioid, mu; Tumor Cells, Cultured

1998
Macrophage behavior associated with acute and chronic exposure to HIV GP120, morphine and anandamide: endothelial implications.
    International journal of cardiology, 1998, Apr-30, Volume: 64 Suppl 1

    Topics: Analysis of Variance; Arachidonic Acids; Cannabinoids; Cell Movement; Chemotaxis; Disease Susceptibility; Endocannabinoids; Enkephalin, Methionine; HIV Envelope Protein gp120; HIV Infections; Humans; In Vitro Techniques; Interleukin-1; Macrophages; Morphine; Narcotics; Nitric Oxide; Penicillamine; Polyunsaturated Alkamides

1998
Effects of peptidase inhibitors, [D-Ala2, Met5]-enkephalinamide and antiserum to methionine-enkephalin microinjected into the caudal periaqueductal gray on morphine withdrawal in rats.
    Japanese journal of pharmacology, 1998, Volume: 78, Issue:4

    Topics: Animals; Enkephalin, Methionine; Enkephalins; Immune Sera; Male; Microinjections; Morphine; Morphine Dependence; Naloxone; Periaqueductal Gray; Protease Inhibitors; Protein Precursors; Rats; Rats, Sprague-Dawley; RNA, Messenger; Substance Withdrawal Syndrome

1998
Opioids in the hypothalamus control dopamine and acetylcholine levels in the nucleus accumbens.
    Brain research, 2010, Feb-02, Volume: 1312

    Topics: 3,4-Dihydroxyphenylacetic Acid; Acetylcholine; Analgesics, Opioid; Animals; Dopamine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Methionine; Homovanillic Acid; Male; Microdialysis; Microinjections; Morphine; Naloxone; Narcotic Antagonists; Neural Pathways; Nucleus Accumbens; Paraventricular Hypothalamic Nucleus; Rats; Rats, Sprague-Dawley

2010
Opioids in the hypothalamic paraventricular nucleus stimulate ethanol intake.
    Alcoholism, clinical and experimental research, 2010, Volume: 34, Issue:2

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Alcohol Drinking; Analgesics, Opioid; Animals; Central Nervous System Depressants; Drinking; Eating; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Methionine; Ethanol; Male; Microinjections; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Paraventricular Hypothalamic Nucleus; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Stimulation, Chemical

2010