Compounds > enkephalin-met, arg(6)-phe(7)-
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enkephalin-met, arg(6)-phe(7)- and thiorphan

enkephalin-met, arg(6)-phe(7)- has been researched along with thiorphan in 5 studies

Compound Research Comparison

Studies
(enkephalin-met, arg(6)-phe(7)-)		Trials
(enkephalin-met, arg(6)-phe(7)-)		Recent Studies (post-2010)
(enkephalin-met, arg(6)-phe(7)-)		Studies
(thiorphan)		Trials
(thiorphan)		Recent Studies (post-2010) (thiorphan)
1891106655082

Protein Interaction Comparison

ProteinTaxonomyenkephalin-met, arg(6)-phe(7)- (IC50)thiorphan (IC50)
ThermolysinBacillus thermoproteolyticus9.5
NeprilysinRattus norvegicus (Norway rat)0.0058
NeprilysinOryctolagus cuniculus (rabbit)0.0085
NeprilysinHomo sapiens (human)0.0024
Angiotensin-converting enzyme Homo sapiens (human)0.2281
Angiotensin-converting enzymeOryctolagus cuniculus (rabbit)0.42
NeprilysinSus scrofa (pig)0.0062

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19904 (80.00)18.7374
1990's1 (20.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Autry, WL; Barbaz, BS; Norman, JA1
Chou, J; Costa, E; Del Rio, J; Tang, J; Yang, HY1
Carenzi, A; Della Bella, D; Frigeni, V; Reggiani, A1
Costa, E; Harsing, LG; Majane, EM; Yang, HY1
Botyánszki, J; Fehér, E; Hepp, J; Magyar, A; Medzihradszky, K; Rónai, AZ1

Other Studies

5 other study(ies) available for enkephalin-met, arg(6)-phe(7)- and thiorphan

ArticleYear
Angiotensin-converting enzyme inhibitors potentiate the analgesic activity of [Met]-enkephalin-Arg6-Phe7 by inhibiting its degradation in mouse brain.
    Molecular pharmacology, 1985, Volume: 28, Issue:6

    Topics: Analgesics; Angiotensin-Converting Enzyme Inhibitors; Animals; Brain; Captopril; Enalapril; Enalaprilat; Enkephalin, Methionine; Hydrolysis; In Vitro Techniques; Male; Mice; Mice, Inbred Strains; Peptidyl-Dipeptidase A; Synaptic Membranes; Thiorphan; Tiopronin

1985
Action of peptidase inhibitors on methionine5-enkephalin-arginine6-phenylalanine7 (YGGFMRF) and methionine5-enkephalin (YGGFM) metabolism and on electroacupuncture antinociception.
    The Journal of pharmacology and experimental therapeutics, 1984, Volume: 230, Issue:2

    Topics: Acupuncture Therapy; Analgesia; Animals; Captopril; Electronarcosis; Enkephalin, Methionine; Leucine; Male; Perfusion; Protease Inhibitors; Rats; Rats, Inbred Strains; Spinal Cord; Substance P; Thiorphan; Tiopronin

1984
Effect of bestatin and thiorphan on [Met5]enkephalin-Arg6-Phe7-induced analgesia.
    European journal of pharmacology, 1984, Oct-15, Volume: 105, Issue:3-4

    Topics: Amino Acids, Sulfur; Aminopeptidases; Analgesia; Animals; Enkephalin, Methionine; Leucine; Male; Neprilysin; Protease Inhibitors; Rats; Rats, Inbred Strains; Thiorphan; Tiopronin

1984
Possible role of dipeptidyl carboxypeptidase n the metabolism of Met5-enkephalin and Met5-enkephalin-Arg6-Phe7.
    Advances in biochemical psychopharmacology, 1982, Volume: 33

    Topics: Animals; Captopril; Cattle; Chlorides; Corpus Striatum; Endopeptidases; Enkephalin, Methionine; Neprilysin; Protease Inhibitors; Rats; Rats, Inbred Strains; Thiorphan; Tiopronin

1982
Substrate- and inhibitor-specificity of a non-endothelial enzyme which forms [Met5]-enkephalin from [Met5]-enkephalin-Arg6,Phe7 in isolated rabbit ear artery: pharmacological characterization.
    Neuropeptides, 1995, Volume: 28, Issue:3

    Topics: Amino Acid Sequence; Angiotensin I; Animals; Arteries; Bradykinin; Captopril; Disease Models, Animal; Ear, External; Enalapril; Endopeptidases; Endothelium, Vascular; Enkephalin, Methionine; Male; Migraine Disorders; Molecular Sequence Data; Rabbits; Substrate Specificity; Thiorphan

1995