enkephalin-met, arg(6)-phe(7)- has been researched along with naltrexone in 11 studies
| Studies (enkephalin-met, arg(6)-phe(7)-) | Trials (enkephalin-met, arg(6)-phe(7)-) | Recent Studies (post-2010) (enkephalin-met, arg(6)-phe(7)-) | Studies (naltrexone) | Trials (naltrexone) | Recent Studies (post-2010) (naltrexone) |
|---|---|---|---|---|---|
| 189 | 1 | 10 | 8,745 | 1,228 | 2,642 |
| Protein | Taxonomy | enkephalin-met, arg(6)-phe(7)- (IC50) | naltrexone (IC50) |
|---|---|---|---|
| Cytochrome P450 2D6 | Homo sapiens (human) | 1 | |
| Delta-type opioid receptor | Mus musculus (house mouse) | 0.0051 | |
| Delta-type opioid receptor | Rattus norvegicus (Norway rat) | 0.0063 | |
| Kappa-type opioid receptor | Mus musculus (house mouse) | 0.006 | |
| Mu-type opioid receptor | Rattus norvegicus (Norway rat) | 0.0005 | |
| Kappa-type opioid receptor | Rattus norvegicus (Norway rat) | 0.0005 | |
| Mu-type opioid receptor | Homo sapiens (human) | 0.006 | |
| Delta-type opioid receptor | Homo sapiens (human) | 0.0319 | |
| Kappa-type opioid receptor | Cavia porcellus (domestic guinea pig) | 0.0093 | |
| Kappa-type opioid receptor | Homo sapiens (human) | 0.0377 | |
| Mu-type opioid receptor | Mus musculus (house mouse) | 0.0076 | |
| Mu-type opioid receptor | Cavia porcellus (domestic guinea pig) | 0.0004 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (9.09) | 18.7374 |
| 1990's | 2 (18.18) | 18.2507 |
| 2000's | 7 (63.64) | 29.6817 |
| 2010's | 1 (9.09) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Costa, E; Mocchetti, I; Ritter, A | 1 |
| Iwamoto, Y; Kamei, J; Kasuya, Y; Misawa, M; Nagase, H | 1 |
| Benyhe, S; Borsodi, A; Medzihradszky, K; Orosz, G; Rónai, AZ; Sartania, N; Szatmári, I | 1 |
| Cheong, YP; Cho, KP; Kim, CJ; Kim, JK; Kim, KW; Kwun, J; Woo, RS | 1 |
| Caffrey, JL; Farias, M; Jackson, KE; Yoshishige, D | 1 |
| Bujdosó, E; Farkas, J; Jászberényi, M; Telegdy, G; Tóth, G; Wollemann, M | 1 |
| Eriksson, PS; Jonsdottir, IH; Naylor, AS; Nyberg, F; Persson, AI; Thorlin, T | 1 |
| Barlow, MA; Caffrey, JL; Deo, S; Johnson, S | 1 |
| Barlow, MA; Caffrey, JL; Deo, SH; Johnson-Davis, S; Yoshishige, D | 1 |
| Barlow, M; Caffrey, JL; Davis, S; Deo, SH; Farias, M; Yoshishige, D | 1 |
| Bagosi, Z; Csabafi, K; Jászberényi, M; Telegdy, G; Tóth, G; Wollemann, M | 1 |
11 other study(ies) available for enkephalin-met, arg(6)-phe(7)- and naltrexone
| Article | Year |
|---|---|
Down-regulation of proopiomelanocortin synthesis and beta-endorphin utilization in hypothalamus of morphine-tolerant rats.
Topics: Animals; beta-Endorphin; Corpus Striatum; Drug Tolerance; Enkephalin, Methionine; Enkephalins; Hypothalamus; Male; Morphine; Naltrexone; Pro-Opiomelanocortin; Protein Precursors; Rats; Rats, Inbred Strains; Reference Values; RNA, Messenger; Substance Withdrawal Syndrome | 1989 |
Antitussive effect of [Met5]enkephalin-Arg6-Phe7 in mice.
Topics: Animals; Antitussive Agents; Capsaicin; Cough; Dose-Response Relationship, Drug; Enkephalin, Methionine; Injections, Intraventricular; Male; Mice; Naltrexone; Narcotic Antagonists; Receptors, Opioid, kappa; Receptors, Opioid, mu | 1994 |
Irreversible labelling of the opioid receptors by a melphalan-substituted [Met5]enkephalin-Arg-Phe derivative.
Topics: Affinity Labels; Amino Acid Sequence; Amino Acid Substitution; Animals; Binding Sites; Binding, Competitive; Brain; Enkephalin, Methionine; Female; Guinea Pigs; Male; Melphalan; Membranes; Naloxone; Naltrexone; Narcotic Antagonists; Radioligand Assay; Rats; Receptors, Opioid | 1999 |
Receptor selectivity of Met-enkephalin-Arg6-Phe7, an endogenous opioid peptide, in cerebral cortex of human and rat.
Topics: Adult; Animals; Benzeneacetamides; Benzomorphans; Binding Sites; Cerebral Cortex; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Methionine; Ethylketocyclazocine; Female; Humans; Male; Naloxone; Naltrexone; Norepinephrine; Oligopeptides; Peptide Fragments; Peptides; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Somatostatin | 2000 |
Cardiac enkephalins interrupt vagal bradycardia via delta 2-opioid receptors in sinoatrial node.
Topics: Analgesics; Analgesics, Opioid; Animals; Benzylidene Compounds; Bradycardia; Dogs; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Methionine; Naltrexone; Narcotic Antagonists; Oligopeptides; Opioid Peptides; Quinolines; Receptors, Opioid, delta; Sinoatrial Node; Vagus Nerve | 2003 |
Behavioral and neuroendocrine actions of the Met-enkephalin-related peptide MERF.
Topics: Analysis of Variance; Animals; Behavior, Animal; Corticotropin-Releasing Hormone; Dopamine; Enkephalin, Methionine; Exploratory Behavior; Haloperidol; Hormone Antagonists; Hypothalamo-Hypophyseal System; Male; Mice; Motor Activity; Naloxone; Naltrexone; Narcotic Antagonists; Neostriatum; Organ Culture Techniques; Peptide Fragments; Pituitary-Adrenal System | 2003 |
Differential regulation of hippocampal progenitor proliferation by opioid receptor antagonists in running and non-running spontaneously hypertensive rats.
Topics: Adrenocorticotropic Hormone; Animals; Behavior, Animal; beta-Endorphin; Bromodeoxyuridine; Cell Division; Corticosterone; Enkephalin, Methionine; Female; Hippocampus; Motor Activity; Naltrexone; Narcotic Antagonists; Narcotics; Physical Conditioning, Animal; Radioimmunoassay; Random Allocation; Rats; Rats, Inbred SHR; Receptors, Opioid; Running | 2004 |
Vagotonic effects of enkephalin are not mediated by sympatholytic mechanisms.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Dogs; Enkephalin, Methionine; Female; Heart Rate; Male; Naltrexone; Receptors, Opioid, kappa; Sympatholytics; Vagus Nerve | 2006 |
Repeated delta1-opioid receptor stimulation reduces delta2-opioid receptor responses in the SA node.
Topics: Analgesics; Analgesics, Opioid; Animals; Benzylidene Compounds; Bradycardia; Dogs; Dose-Response Relationship, Drug; Enkephalin, Methionine; Female; Male; Microdialysis; Naltrexone; Narcotic Antagonists; Oligopeptides; Quinolines; Receptors, Opioid, delta; Sinoatrial Node; Stimulation, Chemical; Vagus Nerve | 2006 |
The monosialosyl ganglioside GM-1 reduces the vagolytic efficacy of delta2-opioid receptor stimulation.
Topics: Analgesics, Opioid; Animals; Benzylidene Compounds; Bradycardia; Dogs; Dose-Response Relationship, Drug; Enkephalin, Methionine; Female; G(M1) Ganglioside; Male; Naltrexone; Narcotic Antagonists; Oligopeptides; Receptors, Opioid, delta; Sinoatrial Node; Stimulation, Chemical; Vagus Nerve | 2006 |
The action of a synthetic derivative of Met5-enkephalin-Arg6-Phe7 on behavioral and endocrine responses.
Topics: Animals; Behavior, Animal; Enkephalin, Methionine; Enkephalins; Hypothalamo-Hypophyseal System; Male; Mice; Mice, Inbred Strains; Naloxone; Naltrexone; Oligopeptides; Pituitary-Adrenal System | 2011 |