enkephalin-met, arg(6)-phe(7)- has been researched along with naloxone in 21 studies
Studies (enkephalin-met, arg(6)-phe(7)-) | Trials (enkephalin-met, arg(6)-phe(7)-) | Recent Studies (post-2010) (enkephalin-met, arg(6)-phe(7)-) | Studies (naloxone) | Trials (naloxone) | Recent Studies (post-2010) (naloxone) |
---|---|---|---|---|---|
189 | 1 | 10 | 20,134 | 1,257 | 3,321 |
Protein | Taxonomy | enkephalin-met, arg(6)-phe(7)- (IC50) | naloxone (IC50) |
---|---|---|---|
Cytochrome P450 2D6 | Homo sapiens (human) | 2 | |
Delta-type opioid receptor | Mus musculus (house mouse) | 0.043 | |
Delta-type opioid receptor | Rattus norvegicus (Norway rat) | 0.0219 | |
Mu-type opioid receptor | Rattus norvegicus (Norway rat) | 0.0019 | |
Kappa-type opioid receptor | Rattus norvegicus (Norway rat) | 0.0019 | |
Mu-type opioid receptor | Homo sapiens (human) | 0.0397 | |
Delta-type opioid receptor | Homo sapiens (human) | 0.1896 | |
Kappa-type opioid receptor | Cavia porcellus (domestic guinea pig) | 0.05 | |
Kappa-type opioid receptor | Homo sapiens (human) | 0.0795 | |
Mu-type opioid receptor | Mus musculus (house mouse) | 0.0154 | |
Mu-type opioid receptor | Cavia porcellus (domestic guinea pig) | 0.0089 | |
Beta-2 adrenergic receptor | Cavia porcellus (domestic guinea pig) | 0.0055 |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 10 (47.62) | 18.7374 |
1990's | 5 (23.81) | 18.2507 |
2000's | 5 (23.81) | 29.6817 |
2010's | 1 (4.76) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Classen, M; Erberl, T; Madaus, S; Schusdziarra, V; Seufferlein, T | 1 |
Scharrer, B; Shipp, MA; Stefano, GB | 1 |
Rand, MJ; Wong-Dusting, H | 1 |
Greenberg, MJ; Tse, SY; Wong, TM | 1 |
Bitar, KN; Makhlouf, GM | 1 |
Hirst, M; Kavaliers, M; Teskey, GC | 1 |
Giles, TD; Sander, GE | 1 |
Audigier, Y; Cros, J; Mazarguil, H; Rossier, J | 1 |
Gayton, RJ | 1 |
Fei, H; Han, JS; Zhou, ZF | 1 |
Chapman, RW; Chipkin, RE | 1 |
Inturrisi, CE; Lewis, RV; Stein, S; Stern, AS; Udenfriend, S; Umans, JG; Wolff, D | 1 |
Benyhe, S; Farkas, J; Tóth, G; Wollemann, M | 1 |
Benyhe, S; Borsodi, A; Medzihradszky, K; Orosz, G; Rónai, AZ; Sartania, N; Szatmári, I | 1 |
Chien, GL; Takasaki, Y; van Winkle, DM; Wolff, RA | 1 |
Benyhe, S; Bozó, B; Farkas, J; Szucs, M; Tóth, G; Wollemann, M | 1 |
Cheong, YP; Cho, KP; Kim, CJ; Kim, JK; Kim, KW; Kwun, J; Woo, RS | 1 |
Koob, GF; Terenius, L; Walker, JR | 1 |
Bujdosó, E; Farkas, J; Jászberényi, M; Telegdy, G; Tóth, G; Wollemann, M | 1 |
Jin, XL; Kobayashi, H; Kosaka, K; Oka, T; Takahashi, S; Yoshikawa, M | 1 |
Bagosi, Z; Csabafi, K; Jászberényi, M; Telegdy, G; Tóth, G; Wollemann, M | 1 |
21 other study(ies) available for enkephalin-met, arg(6)-phe(7)- and naloxone
Article | Year |
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Effect of met-enkephalin and met-enkephalin-Arg6-Phe7 on bombesin-like immunoreactivity (BLI), somatostatin and gastrin secretion from the perfused rat stomach.
Topics: Animals; Bombesin; Enkephalin, Methionine; Gastric Mucosa; Gastrins; Naloxone; Rats; Somatostatin | 1990 |
A possible immunoregulatory function for [Met]-enkephalin-Arg6-Phe7 involving human and invertebrate granulocytes.
Topics: Animals; Bivalvia; Cell Movement; Enkephalin, Methionine; Granulocytes; Humans; Immune System; Naloxone; Oligopeptides | 1991 |
Effects of the opioid peptides [Met5]enkephalin-Arg6-Phe7 and [Met5]enkephalin-Arg6-Gly7-Leu8 on cholinergic neurotransmission in the rabbit isolated atria.
Topics: Animals; Electric Stimulation; Enkephalin, Leucine; Enkephalin, Methionine; Female; Heart; Heart Rate; In Vitro Techniques; Male; Naloxone; Parasympathetic Nervous System; Propranolol; Rabbits; Synaptic Transmission | 1987 |
Cardiovascular effects of intraventricular injection of FMRFamide, Met-enkephalin and their common analogues in the rat.
Topics: Animals; Blood Pressure; Enkephalin, Methionine; FMRFamide; Injections, Intraventricular; Male; Naloxone; Oligopeptides; Rats; Structure-Activity Relationship | 1985 |
Selective presence of opiate receptors on intestinal circular muscle cells.
Topics: Acetylcholine; Animals; Atropine; Benzomorphans; beta-Endorphin; Dose-Response Relationship, Drug; Dynorphins; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Guinea Pigs; Humans; Jejunum; Muscle Contraction; Muscle, Smooth; Naloxone; Peptide Fragments; Proglumide; Receptors, Opioid; Sincalide | 1985 |
The effects of opioid and FMRF-amide peptides on thermal behavior in the snail.
Topics: Animals; beta-Endorphin; Body Temperature; Body Temperature Regulation; Dose-Response Relationship, Drug; Endorphins; Enkephalin, Methionine; Humans; Morphine; Naloxone; Snails; Stereotyped Behavior | 1985 |
Cardiovascular activities of intravenous methionine-enkephalin-Arg6-Phe7 and methionine-enkephalin-Arg6-Gly7-Leu8 in the conscious dog.
Topics: Animals; Blood Pressure; Cardiovascular System; Dogs; Endopeptidases; Enkephalin, Methionine; Heart Rate; Naloxone; Structure-Activity Relationship | 1985 |
Met-enkephalin[Arg6,Phe7] interacts with the kappa-receptors on guinea-pig ileum.
Topics: Animals; Dose-Response Relationship, Drug; Endorphins; Enkephalin, Methionine; Enkephalins; Guinea Pigs; Ileum; Naloxone; Receptors, Opioid | 1980 |
Mammalian neuronal actions of FMRFamide and the structurally related opioid Met-enkephalin-Arg6-Phe7.
Topics: Action Potentials; Animals; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; FMRFamide; Male; Medulla Oblongata; Naloxone; Neurons, Efferent; Oligopeptides; Rats; Rats, Inbred Strains; Receptors, Opioid | 1982 |
Met-enkephalin-Arg6-Phe7-like immunoreactive substances mediate electroacupuncture analgesia in the periaqueductal gray of the rabbit.
Topics: Acupuncture Therapy; Animals; Brain Mapping; Captopril; Combined Modality Therapy; Electric Stimulation Therapy; Enkephalin, Methionine; Male; Naloxone; Pain; Pain Management; Periaqueductal Gray; Rabbits | 1984 |
Enkephalin heptapeptide (Tyr-Gly-Gly-Phe-Met-Arg-Phe)-induced bronchospasm in guinea pigs: a non-naloxone reversible phenomenon.
Topics: Animals; Bronchi; Chromones; Dose-Response Relationship, Drug; Enkephalin, Methionine; Guinea Pigs; Ibuprofen; Imidazoles; Male; Naloxone; Pressure; Trachea; Vagotomy | 1984 |
Analgesic activity of the naturally occurring heptapeptide [Met]enkephalin-Arg6-Phe7.
Topics: Analgesics; Animals; Diarrhea; Diuresis; Dose-Response Relationship, Drug; Endorphins; Enkephalin, Methionine; Enkephalins; Injections, Intravenous; Injections, Intraventricular; Male; Mice; Naloxone; Rats | 1980 |
Characterization of [3H]Met-enkephalin-Arg6-Phe7 binding to multiple sites in rat and guinea pig cerebellum.
Topics: Animals; Binding Sites; Binding, Competitive; Cerebellum; Enkephalin, Methionine; Guinea Pigs; Naloxone; Rats; Rats, Wistar; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, sigma; Species Specificity | 1999 |
Irreversible labelling of the opioid receptors by a melphalan-substituted [Met5]enkephalin-Arg-Phe derivative.
Topics: Affinity Labels; Amino Acid Sequence; Amino Acid Substitution; Animals; Binding Sites; Binding, Competitive; Brain; Enkephalin, Methionine; Female; Guinea Pigs; Male; Melphalan; Membranes; Naloxone; Naltrexone; Narcotic Antagonists; Radioligand Assay; Rats; Receptors, Opioid | 1999 |
Met5-enkephalin protects isolated adult rabbit cardiomyocytes via delta-opioid receptors.
Topics: Animals; beta-Endorphin; Cell Hypoxia; Cells, Cultured; Enkephalin, Leucine; Enkephalin, Methionine; Heart; Ischemic Preconditioning; Male; Models, Cardiovascular; Morphine; Myocardial Ischemia; Myocardium; Naloxone; Rabbits; Rats; Receptors, Opioid, delta | 1999 |
Receptor binding and G-protein activation by new Met5-enkephalin-Arg6-Phe7 derived peptides.
Topics: Animals; Brain; Enkephalin, Methionine; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanylyl Imidodiphosphate; Naloxone; Radioligand Assay; Rana esculenta; Rats; Receptors, Opioid, kappa | 2000 |
Receptor selectivity of Met-enkephalin-Arg6-Phe7, an endogenous opioid peptide, in cerebral cortex of human and rat.
Topics: Adult; Animals; Benzeneacetamides; Benzomorphans; Binding Sites; Cerebral Cortex; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Methionine; Ethylketocyclazocine; Female; Humans; Male; Naloxone; Naltrexone; Norepinephrine; Oligopeptides; Peptide Fragments; Peptides; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Somatostatin | 2000 |
Conditioned opioid withdrawal decreases nociceptin/orphanin FQ levels in the frontal cortex and olfactory tubercle.
Topics: Animals; Behavior, Animal; Conditioning, Psychological; Cues; Down-Regulation; Dynorphins; Electric Stimulation; Enkephalin, Methionine; Male; Naloxone; Narcotic Antagonists; Nociceptin; Olfactory Pathways; Opioid Peptides; Opioid-Related Disorders; Prefrontal Cortex; Rats; Rats, Wistar; Reinforcement, Psychology; Stress, Physiological; Substance Withdrawal Syndrome | 2002 |
Behavioral and neuroendocrine actions of the Met-enkephalin-related peptide MERF.
Topics: Analysis of Variance; Animals; Behavior, Animal; Corticotropin-Releasing Hormone; Dopamine; Enkephalin, Methionine; Exploratory Behavior; Haloperidol; Hormone Antagonists; Hypothalamo-Hypophyseal System; Male; Mice; Motor Activity; Naloxone; Naltrexone; Narcotic Antagonists; Neostriatum; Organ Culture Techniques; Peptide Fragments; Pituitary-Adrenal System | 2003 |
The enhancing effects of peptidase inhibitors on the antinociceptive action of [Met5]enkephalin-Arg6-Phe7 in rats.
Topics: Analgesics; Animals; Captopril; Dose-Response Relationship, Drug; Drug Synergism; Enkephalin, Methionine; Glycopeptides; Injections, Intraventricular; Injections, Subcutaneous; Male; Naloxone; Narcotic Antagonists; Pain; Pain Measurement; Peptides; Protease Inhibitors; Rats; Rats, Wistar | 2007 |
The action of a synthetic derivative of Met5-enkephalin-Arg6-Phe7 on behavioral and endocrine responses.
Topics: Animals; Behavior, Animal; Enkephalin, Methionine; Enkephalins; Hypothalamo-Hypophyseal System; Male; Mice; Mice, Inbred Strains; Naloxone; Naltrexone; Oligopeptides; Pituitary-Adrenal System | 2011 |