enkephalin-met, arg(6)-phe(7)- has been researched along with enkephalin, methionine in 181 studies
Studies (enkephalin-met, arg(6)-phe(7)-) | Trials (enkephalin-met, arg(6)-phe(7)-) | Recent Studies (post-2010) (enkephalin-met, arg(6)-phe(7)-) | Studies (enkephalin, methionine) | Trials (enkephalin, methionine) | Recent Studies (post-2010) (enkephalin, methionine) |
---|---|---|---|---|---|
189 | 1 | 10 | 4,439 | 45 | 225 |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 104 (57.46) | 18.7374 |
1990's | 35 (19.34) | 18.2507 |
2000's | 32 (17.68) | 29.6817 |
2010's | 9 (4.97) | 24.3611 |
2020's | 1 (0.55) | 2.80 |
Authors | Studies |
---|---|
Bennett, DJ; Cripps, MM | 1 |
Nyberg, F; Terenius, L; Vaerøy, H | 1 |
Chen, XH; Han, JS; Hao, JX; Sun, SL; Terenius, L; Xu, XJ; Yan, SC; Yuan, Y | 1 |
Duve, H; Scott, AG; Sewell, JC; Thorpe, A | 1 |
Arbiser, ZK; Beltz, BS | 1 |
Classen, M; Erberl, T; Madaus, S; Schusdziarra, V; Seufferlein, T | 1 |
Scharrer, B; Shipp, MA; Stefano, GB | 1 |
Coulter, CL; Giraud, AS; Hooper, SB; McMillen, IC; Parker, L | 1 |
Allen, RG; Low, KG; Melner, MH | 1 |
Duve, H; Thorpe, A | 2 |
Haglund, L; Köhler, C; Swanson, LW; Wu, JY | 1 |
Adams, M; Boarder, MR; Marriott, D | 1 |
Costa, E; Mocchetti, I; Ritter, A | 1 |
Familari, M; Funder, J; Giraud, AS; Parker, L; Reichman, C; Smith, AI | 1 |
Brumbaugh, DR; Erdelyi, E; Evans, CJ; Maidment, NT; Rudolph, VD | 1 |
Rand, MJ; Wong-Dusting, H | 1 |
Honzawa, M; Matsuo, H; Miyata, A; Mizuno, K; Tohyama, M | 1 |
Greenberg, MJ; Tse, SY; Wong, TM | 1 |
Bitar, KN; Makhlouf, GM | 1 |
Kwok, YN; McIntosh, HS; Nishimura, E | 1 |
Haddon, WF; Holman, GM; Nachman, RJ | 1 |
Dockray, GJ; Varro, A; Watkinson, A; Young, J | 1 |
Costa, E; Iadarola, MJ; Mellstrom, B; Yang, HY | 1 |
Costa, E; Iadarola, MJ; Mellstrom, B | 1 |
Costa, E; Mocchetti, I | 1 |
Camargo, AC; Ribeiro, MJ; Schwartz, WN | 1 |
Autry, WL; Barbaz, BS; Norman, JA | 1 |
Garzón, J; Sánchez-Blázquez, P | 1 |
Hazato, T; Kase, R; Katayama, T; Sekine, R; Takagi, H | 1 |
Adams, M; Boarder, MR | 1 |
Folkesson, R; Lindberg, B; Lyrenäs, S; Nyberg, F; Terenius, L | 1 |
Hirst, M; Kavaliers, M; Teskey, GC | 1 |
Häppölä, O; Päivärinta, H; Panula, P; Soinila, S | 1 |
Dockray, GJ; Ferri, GL; Watkinson, A | 1 |
Dockray, GJ; Gregory, H; Watkinson, A; Young, J | 1 |
Hazato, T; Hideshima, C; Kase, R | 1 |
Altschuler, RA; Maderdrut, JL; Merchenthaler, I; Petrusz, P | 1 |
Maderdrut, JL; Merchenthaler, I; Okado, N; Oppenheim, RW; Sundberg, DK | 1 |
Araujo, DM; Collier, B | 1 |
Beaumont, A; Hughes, J; Metters, KM; Rossier, J | 1 |
Giles, TD; Sander, GE | 1 |
Häppölä, O; Joh, TH; Päivärinta, H; Panula, P; Soinila, S | 1 |
Fei, H; Han, JS; Zhou, ZF | 2 |
Jönsson, AC | 1 |
Bailey, C; Kitchen, I | 1 |
Boarder, MR; Contractor, H; Marriott, D; McArdle, W | 1 |
Chou, J; Costa, E; Tang, F; Tang, J | 1 |
Corti, V; Fantozzi, R; Ledda, F; Mantelli, L | 1 |
Cottrell, GA; Davies, NW; Green, KA | 1 |
Bourhim, N; Cantau, P; Castanas, E; Giraud, P; Oliver, C | 1 |
Rubini, P; Schulz, R; Wüster, M | 1 |
Boudouresque, F; Cantau, P; Castanas, E; Cesselin, F; Chabrier, PE; Conte-Devolx, B; Cupo, A; Drissi, R; Eiden, LE; Giraud, P | 1 |
Cox, BM; Molineaux, CJ; Rosenberger, JG | 1 |
Quirion, R | 1 |
Chou, J; Costa, E; Tang, J; Yang, HY | 3 |
Fujita, T; Imura, H; Kobayashi, S; Mochizuki, T; Nakao, K; Ohashi, T; Uchida, T; Yanaihara, C; Yanaihara, N; Yoshimasa, T | 1 |
Chou, J; Costa, E; Del Rio, J; Tang, J; Yang, HY | 1 |
Helen, P; Hervonen, A; Panula, P; Rapoport, SI; Yang, HY | 1 |
Costa, E; Giorgi, O; Mocchetti, I; Schwartz, JP | 1 |
Kimura, S; Lewis, RV; Rossier, J; Stein, S; Stern, AS; Udenfriend, S | 1 |
Audigier, Y; Cros, J; Mazarguil, H; Rossier, J | 1 |
Gayton, RJ | 1 |
Bajusz, S; Berzétei, IP; Hársing, LG; Rónai, AZ; Vizi, ES | 1 |
Chou, J; Costa, E; Tang, J; Yang, HY; Zhang, AZ | 1 |
Chaminade, M; Cupo, A; Giraud, P; Patey, G; Rossier, J | 1 |
Dockray, GJ; Williams, RG | 2 |
Bajusz, S; Hársing, LG; Rónai, AZ; Somogyi, GT; Umezawa, H; Vizi, ES | 1 |
Chou, J; Costa, E; Tang, J | 1 |
Bu'Lock, AJ; Dockray, GJ; Vaillant, C | 1 |
Panula, P; Tarkkanen, A; Tervo, K; Tervo, T | 1 |
Imura, H; Kobayashi, S; Nakao, K; Ohashi, T; Uchida, T; Verhofstad, AA; Yanaihara, N | 1 |
Carenzi, A; Della Bella, D; Frigeni, V; Reggiani, A | 1 |
Eränkö, L; Eränkö, O; Lehtosalo, JI; Panula, P; Ylikoski, J | 1 |
Church, AC; Wang, YN; Wyatt, RJ | 1 |
Hamada, S; Ikeda, Y; Ishihara, T; Manno, M; Morii, N; Nakao, K; Sakamoto, M; Shimbo, S; Suda, M; Yoshimasa, T | 1 |
Boarder, MR; McArdle, W | 1 |
Liston, D; Patey, G; Rossier, J; Vanderhaeghen, JJ; Verbanck, P | 1 |
Inoki, R; Kuto, T; Maeda, S | 1 |
Hársing, LG; Rónai, AZ; Serfózó, P; Vizi, SE | 1 |
Chaminade, M; Cupo, A; Morgat, JL; Patey, G; Rossier, J | 1 |
Herz, A; Mehraein, P; Pasi, A; Pittius, CW; Seizinger, BR | 2 |
Ikeda, Y; Imura, H; Nakao, K; Sakamoto, M; Suda, M; Yanaihara, N; Yoshimasa, T | 2 |
Leung, M; Stefano, GB | 1 |
Ikeda, Y; Imura, H; Nakao, K; Sakamoto, M; Suda, M; Yoshimasa, T | 1 |
Castanas, E; Giraud, P; Oliver, C; Patey, G; Rossier, J | 1 |
Leung, MK; Stefano, GB | 1 |
Chapman, RW; Chipkin, RE | 1 |
Dockray, GJ; Giraud, AS; Williams, RG | 1 |
Costa, E; Harsing, LG; Majane, EM; Yang, HY | 1 |
Benuck, M; Berg, MJ; Marks, N | 2 |
Dandekar, S; Kranzler, LS; Liang, CM; Sabol, SL | 1 |
Costa, E; Panula, P; Tang, J; Yang, HY | 1 |
Ikeda, Y; Imura, H; Nakao, K; Sakamoto, M; Shimbo, S; Suda, M; Takasu, K; Yanaihara, N; Yoshimasa, T | 1 |
Iadarola, MJ; Majane, EA; Yang, HY | 1 |
Costa, E; Guidotti, A; Hanbauer, I; Saiani, L | 1 |
Inturrisi, CE; Lewis, RV; Stein, S; Stern, AS; Udenfriend, S; Umans, JG; Wolff, D | 1 |
Costa, E; Majane, E; Yang, HY | 1 |
Dockray, GJ; Gayton, RJ; Osborne, NN; Vaillant, C; Williams, RG | 1 |
Barchas, JD; Boarder, MR; Lockfeld, AJ | 2 |
Costa, E; Tang, J; Yang, HY | 1 |
Benuck, M; Berg, MJ; Marks, N; Sachs, L; Stern, F | 1 |
Ikeda, Y; Imura, H; Nakao, K; Numa, S; Yanaihara, N; Yoshimasa, T | 1 |
Barchas, JD; Chang, JK; Evans, CJ; Fuchs, I; Mues, G; Weber, E; Wei, ET | 1 |
Dean, DM; Livett, BG; Rossier, J; Udenfriend, S | 1 |
Marks, N; Sachs, L; Stern, F | 1 |
Iukhananov, RIu; Klodt, PM; Maĭskiĭ, AI; Nyberg, F; Rat'kin, AE; Shemanov, AIu | 1 |
Botyánszki, J; Fehér, E; Hepp, J; Magyar, A; Medzihradszky, K; Rónai, AZ | 1 |
Barron, BA; Caffrey, JL; Gaugl, JF; Mateo, Z; Napier, LD | 1 |
Finck, AD; Ngai, SH; Samaniego, E | 1 |
Benyhe, S; Farkas, J; Tóth, G; Wollemann, M | 4 |
Iwamoto, Y; Kamei, J; Kasuya, Y; Misawa, M; Nagase, H | 1 |
Coulter, CL; Hey, NJ; McMillen, IC; Simonetta, G; Young, IR | 1 |
Hong, JS; Hudson, PM; Hung, GH; Lee, DY; McMillian, MK; Thai, L | 1 |
Barron, BA; Caffrey, JL; Gaugl, JF; Oakford, LX | 1 |
Barron, BA; Caffrey, JL; Jones, CE | 1 |
Benjamin, PR; Parish, DC; Smith, FG | 1 |
Barron, BA; Caffrey, JL; Gaugl, JF; Mateo, Z; Napier, L | 1 |
D'Alagni, M; Delfini, M; Di Nola, A; Eisenberg, M; Paci, M; Roda, LG; Veglia, G | 1 |
Armstrong, K; Banerjee, N; Ghilchick, M; Parish, DC; Reed, MJ | 1 |
Hong, JS; Hudson, PM; McMillian, MK; Pennypacker, KR; Sawin, SB; Simmons, KL; Suh, HH; Thai, L; Wu, GC | 1 |
McMillen, IC; Simonetta, G; Young, IR | 1 |
Deddish, PA; Erdös, EG; Jackman, HL; Skidgel, RA | 1 |
Murck, H; Voigt, K; Walther, C; Zittlau, KE | 1 |
Kondrat'ev, BIu; Krylatov, AV; Lishmanov, IuB; Maslov, LN; Ugdyzhekova, DS; Uskina, EV | 1 |
Agustín, P; Asai, M; Linares, G; Matamoros-Trejo, G; Zubieta, M | 1 |
Benyhe, S; Borsodi, A; Medzihradszky, K; Orosz, G; Rónai, AZ; Sartania, N; Szatmári, I | 1 |
Chien, GL; Takasaki, Y; van Winkle, DM; Wolff, RA | 1 |
Bytner, B; Lundeberg, T; Nylander, I; Rosén, A | 1 |
Hallberg, M; Johansson, P; Kindlundh, A; Nyberg, F | 1 |
Benyhe, S; Bozó, B; Farkas, J; Szucs, M; Tóth, G; Wollemann, M | 1 |
Cheong, YP; Cho, KP; Kim, CJ; Kim, JK; Kim, KW; Kwun, J; Woo, RS | 1 |
Barron, BA; Caffrey, JL; Lakatta, EG; Pepe, S; Spurgeon, HA; Younès, A | 1 |
Gustavsson, L; Nylander, I; Ploj, K; Roman, E | 1 |
Franck, J; Lindholm, S; Nylander, I; Ploj, K | 1 |
Caffrey, JL; Farias, M; Jackson, K; Stanfill, A | 1 |
Caffrey, JL; Farias, M; Jackson, KE; Stanfill, A | 1 |
Koob, GF; Terenius, L; Walker, JR | 1 |
Caffrey, JL; Farias, M; Jackson, KE; Yoshishige, D | 1 |
Bujdosó, E; Farkas, J; Jászberényi, M; Telegdy, G; Tóth, G; Wollemann, M | 1 |
Ahmed, M; Bergström, J; Kreicbergs, A; Nylander, I | 1 |
Nylander, I; Ploj, K; Roman, E | 1 |
Caffrey, JL; Farias, M; Jackson, K; Johnson, M | 1 |
Caffrey, JL; Farias, M; Jackson, K; Yoshishige, D | 1 |
Agren, G; Bjellerup, P; Finn, A; Lundeberg, T; Vedin, I | 1 |
Eriksson, PS; Jonsdottir, IH; Naylor, AS; Nyberg, F; Persson, AI; Thorlin, T | 1 |
Eriksson, CJ; Fahlke, C; Marmendal, M; Nylander, I; Roman, E | 1 |
Baraniuk, JN; Clauw, DJ; Cunningham, J; Whalen, G | 1 |
Gustafsson, L; Nylander, I; Ploj, K | 1 |
Caffrey, JL; Lakatta, EG; Pepe, S; Yoshishige, D; Younès, A | 1 |
Barendregt, HP; Calle, M; Desfeux, A; Kozicz, T; Roubos, EW; van der Linden, E; Veening, JG | 1 |
Gustafsson, L; Meyerson, BJ; Nylander, I; Ploj, K; Roman, E | 1 |
Barlow, MA; Caffrey, JL; Deo, S; Johnson, S | 1 |
Ackermann, LW; Buresh, CT; Denning, GM; Dickson, EW; Ludwig, PS | 1 |
Barlow, MA; Caffrey, JL; Deo, SH; Johnson-Davis, S; Yoshishige, D | 1 |
Barlow, M; Caffrey, JL; Davis, S; Deo, SH; Farias, M; Yoshishige, D | 1 |
Jin, XL; Kobayashi, H; Kosaka, K; Oka, T; Takahashi, S; Yoshikawa, M | 1 |
Gustafsson, L; Hoffmann, P; Nylander, I; Oreland, S | 1 |
Cheng, F; McLaughlin, PJ; Verderame, MF; Zagon, IS | 1 |
D'Addario, C; Hansen, M; Johansson, B; Langel, U; Ming, Y; Rigler, R; Schulz, R; Terenius, L; Vukojević, V | 1 |
Babos, F; Benyhe, S; Bojnik, E; Borsodi, A; Boynik, E; Corbani, M; Magyar, A | 1 |
Bagosi, Z; Csabafi, K; Jászberényi, M; Telegdy, G; Tóth, G; Wollemann, M | 1 |
Nylander, I; Palm, S; Roman, E | 1 |
Benyhe, S; Rougeot, C; Tóth, F; Tóth, G; Wollemann, M | 1 |
Lane, DA; Mackie, K; Pickel, VM; Shobin, ET | 1 |
Daoura, L; Nylander, I; Palm, S; Roman, E | 1 |
Granholm, L; Nylander, I; Roman, E | 1 |
Benyhe, S; Benyhe, Z; Borsodi, A; Helyes, Z; Rougeot, C; Toth, G; Wollemann, M | 1 |
Canals, M; Christopoulos, A; Coudrat, T; Lane, JR; Sexton, PM; Thompson, GL | 1 |
Brandner, DD; Dick, RM; Gauthier, EA; Kocharian, A; Lefevre, EM; Mashal, MA; More, SS; Remmers, BC; Retzlaff, CL; Rothwell, PE; Toddes, C; Trieu, BH; Xie, W; Zhang, Y | 1 |
2 review(s) available for enkephalin-met, arg(6)-phe(7)- and enkephalin, methionine
Article | Year |
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Pain, nociception and spinal opioid receptors.
Topics: Animals; Dogs; Dynorphins; Endorphins; Enkephalin, Methionine; Guinea Pigs; Injections, Spinal; Mice; Pain; Rats; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Spinal Cord; Thermosensing; Touch | 1984 |
Vertebrate brain-gut peptides related to FMRFamide and Met-enkephalin Arg6Phe7.
Topics: Animals; Antibody Specificity; Anura; Brain; Cattle; Chickens; Digestive System; Dogs; Endorphins; Enkephalin, Methionine; Enkephalins; FMRFamide; Guinea Pigs; Helix, Snails; Histocytochemistry; Humans; Immunologic Techniques; Oligopeptides; Pancreas; Radioimmunoassay; Rats; Tissue Distribution | 1981 |
1 trial(s) available for enkephalin-met, arg(6)-phe(7)- and enkephalin, methionine
Article | Year |
---|---|
Cerebrospinal fluid levels of opioid peptides in fibromyalgia and chronic low back pain.
Topics: Adult; Aged; Chronic Disease; Enkephalin, Methionine; Fatigue Syndrome, Chronic; Female; Fibromyalgia; Humans; Low Back Pain; Male; Middle Aged; Nociceptin; Opioid Peptides; Pain; Pain Measurement | 2004 |
178 other study(ies) available for enkephalin-met, arg(6)-phe(7)- and enkephalin, methionine
Article | Year |
---|---|
Proenkephalin A derivatives in lacrimal gland: occurrence and regulation of lacrimal function.
Topics: Adenylyl Cyclases; Animals; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; Lacrimal Apparatus; Male; Protein Precursors; Radioimmunoassay; Rats; Rats, Inbred Strains | 1992 |
No evidence for endorphin deficiency in fibromyalgia following investigation of cerebrospinal fluid (CSF) dynorphin A and Met-enkephalin-Arg6-Phe7.
Topics: Adult; Biomarkers; Dynorphins; Endorphins; Enkephalin, Methionine; Female; Fibromyalgia; Humans; Radioimmunoassay; Regression Analysis | 1991 |
Effect of low- and high-frequency TENS on Met-enkephalin-Arg-Phe and dynorphin A immunoreactivity in human lumbar CSF.
Topics: Adult; Dynorphins; Electroacupuncture; Enkephalin, Methionine; Humans; Middle Aged; Radioimmunoassay; Transcutaneous Electric Nerve Stimulation | 1991 |
Chromatographic characterisation and biological activity of neuropeptides immunoreactive to antisera against Met5-enkephalin-Arg6-Phe7 (YGGFMRF) extracted from the blowfly Calliphora vomitoria (Diptera).
Topics: Amino Acid Sequence; Animals; Brain Chemistry; Chromatography; Cross Reactions; Diptera; Enkephalin, Methionine; Ganglia; Molecular Sequence Data; Neuropeptides; Radioimmunoassay; Salivary Glands | 1991 |
SCPB-and FMRFamide-like immunoreactivities in lobster neurons: colocalization of distinct peptides or colabeling of the same peptide(s)?
Topics: Amino Acid Sequence; Animals; Antibodies, Monoclonal; Antibody Specificity; Central Nervous System; Enkephalin, Methionine; Fluorescent Antibody Technique; FMRFamide; Molecular Sequence Data; Nephropidae; Neurons; Neuropeptides | 1991 |
Effect of met-enkephalin and met-enkephalin-Arg6-Phe7 on bombesin-like immunoreactivity (BLI), somatostatin and gastrin secretion from the perfused rat stomach.
Topics: Animals; Bombesin; Enkephalin, Methionine; Gastric Mucosa; Gastrins; Naloxone; Rats; Somatostatin | 1990 |
A possible immunoregulatory function for [Met]-enkephalin-Arg6-Phe7 involving human and invertebrate granulocytes.
Topics: Animals; Bivalvia; Cell Movement; Enkephalin, Methionine; Granulocytes; Humans; Immune System; Naloxone; Oligopeptides | 1991 |
Fetal asphyxia stimulates an increase in fetal plasma catecholamines and [Met]-enkephalin-arg6-phe7 in the late-gestation sheep fetus.
Topics: Animals; Carbon Dioxide; Catecholamines; Enkephalin, Methionine; Epinephrine; Female; Fetal Blood; Fetal Hypoxia; Fetus; Hydrogen-Ion Concentration; Norepinephrine; Oxygen; Pregnancy; Radioimmunoassay; Sheep; Uterus | 1990 |
Association of proenkephalin transcripts with polyribosomes in the heart.
Topics: Animals; Animals, Newborn; Cells, Cultured; Centrifugation, Density Gradient; Corpus Striatum; Enkephalin, Methionine; Enkephalins; Male; Myocardium; Nucleic Acid Hybridization; Polyribosomes; Protein Biosynthesis; Protein Precursors; Rats; Rats, Inbred Strains; Ribonucleases; RNA, Messenger; Transcription, Genetic | 1990 |
Distribution of functional significance of Met-enkephalin-Arg6-Phe7- and Met-enkephalin-Arg6-Gly7-Leu8-like peptides in the blowfly Calliphora vomitoria. II. Immunocytochemical mapping of neuronal pathways in the retrocerebral complex and thoracic ganglio
Topics: Animals; Diptera; Enkephalin, Methionine; Female; Immunohistochemistry; Male; Nervous System | 1990 |
The cytoarchitecture, histochemistry and projections of the tuberomammillary nucleus in the rat.
Topics: Amidines; Animals; Biological Transport; Brain Mapping; Cell Count; Enkephalin, Methionine; Fluorescent Dyes; Glutamate Decarboxylase; Hypothalamus; Male; Neural Pathways; Neurons; Neurotransmitter Agents; Rats; Rats, Inbred Strains; Staining and Labeling | 1985 |
Met-enkephalyl-Arg6-Phe7 immunoreactivity in a human neuroblastoma cell line: effect of dibutyryl 3':5'-cyclic AMP and reserpine.
Topics: 1-Methyl-3-isobutylxanthine; Alprostadil; Bucladesine; Cell Line; Cyclic AMP; Enkephalin, Methionine; Enkephalins; Humans; Neuroblastoma; Peptide Fragments; Protein Precursors; Reserpine | 1986 |
Down-regulation of proopiomelanocortin synthesis and beta-endorphin utilization in hypothalamus of morphine-tolerant rats.
Topics: Animals; beta-Endorphin; Corpus Striatum; Drug Tolerance; Enkephalin, Methionine; Enkephalins; Hypothalamus; Male; Morphine; Naltrexone; Pro-Opiomelanocortin; Protein Precursors; Rats; Rats, Inbred Strains; Reference Values; RNA, Messenger; Substance Withdrawal Syndrome | 1989 |
Generation of Met-enkephalin Arg6Phe7 immunoreactivity by proteolytic cleavage of mammalian plasma precursors by pepsin.
Topics: Animals; Chromatography, Gel; Enkephalin, Methionine; Female; Humans; Molecular Weight; Pepsin A; Protein Precursors; Radioimmunoassay; Rats; Receptors, Opioid; Sheep | 1989 |
Microdialysis of extracellular endogenous opioid peptides from rat brain in vivo.
Topics: Animals; Brain; Enkephalin, Methionine; Enkephalins; Male; Radioimmunoassay; Rats; Rats, Inbred Strains | 1989 |
Distribution and functional significance of Met-enkephalin-Arg6-Phe7- and Met-enkephalin-Arg6-Gly7-Leu8-like peptides in the blowfly Calliphora vomitoria. I. Immunocytochemical mapping of neuronal pathways in the brain.
Topics: Animals; Brain; Brain Chemistry; Cross Reactions; Diptera; Enkephalin, Methionine; Female; Immunoenzyme Techniques; Male; Neural Pathways; Neurons | 1989 |
Effects of the opioid peptides [Met5]enkephalin-Arg6-Phe7 and [Met5]enkephalin-Arg6-Gly7-Leu8 on cholinergic neurotransmission in the rabbit isolated atria.
Topics: Animals; Electric Stimulation; Enkephalin, Leucine; Enkephalin, Methionine; Female; Heart; Heart Rate; In Vitro Techniques; Male; Naloxone; Parasympathetic Nervous System; Propranolol; Rabbits; Synaptic Transmission | 1987 |
Adrenorphin immunoreactivity in rat brain.
Topics: Animals; Brain Chemistry; Chromatography, High Pressure Liquid; Dynorphins; Endorphins; Enkephalin, Methionine; Fluorescent Antibody Technique; Hypothalamus; Peptide Fragments; Protein Precursors; Radioimmunoassay; Rats | 1985 |
Cardiovascular effects of intraventricular injection of FMRFamide, Met-enkephalin and their common analogues in the rat.
Topics: Animals; Blood Pressure; Enkephalin, Methionine; FMRFamide; Injections, Intraventricular; Male; Naloxone; Oligopeptides; Rats; Structure-Activity Relationship | 1985 |
Selective presence of opiate receptors on intestinal circular muscle cells.
Topics: Acetylcholine; Animals; Atropine; Benzomorphans; beta-Endorphin; Dose-Response Relationship, Drug; Dynorphins; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Guinea Pigs; Humans; Jejunum; Muscle Contraction; Muscle, Smooth; Naloxone; Peptide Fragments; Proglumide; Receptors, Opioid; Sincalide | 1985 |
Characterization of opioid peptides in the rat stomach.
Topics: Animals; Chromatography; Dynorphins; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Male; Radioimmunoassay; Radioligand Assay; Rats; Rats, Inbred Strains; Stomach; Trypsin | 1986 |
Structural aspects of gastrin/CCK-like insect leucosulfakinins and FMRF-amide.
Topics: Amino Acid Sequence; Cholecystokinin; Enkephalin, Methionine; FMRFamide; Gastrins; Insect Hormones; Molecular Sequence Data; Neuropeptides; Neurotransmitter Agents; Pyrrolidonecarboxylic Acid; Sequence Homology, Amino Acid | 1988 |
The isolation and chemical characterization of phosphorylated enkephalin-containing peptides from bovine adrenal medulla.
Topics: Adrenal Medulla; Alkaline Phosphatase; Amino Acid Sequence; Animals; Cattle; Chromatography, Gel; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Enkephalin, Methionine; Enkephalins; Molecular Sequence Data; Peptide Fragments; Phosphates; Phosphorylation; Protein Precursors | 1989 |
Inhibition of Met5-enkephalin-Arg6-Phe7 degradation by inhibitors of dipeptidyl carboxypeptidase.
Topics: Animals; Blood-Brain Barrier; Bridged Bicyclo Compounds; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Endopeptidases; Enkephalin, Methionine; Male; Permeability; Protease Inhibitors; Ramipril; Rats; Rats, Inbred Strains | 1986 |
Effect of peptidase inhibitors on [Met5]enkephalin-Arg6-Phe7 and [Met5]enkephalin-Arg6-Gly7-Leu8-induced antinociception.
Topics: Animals; Bridged Bicyclo Compounds; Bridged-Ring Compounds; Drug Synergism; Enkephalin, Methionine; Leucine; Male; Pain Measurement; Protease Inhibitors; Ramipril; Rats; Rats, Inbred Strains | 1987 |
Down regulation of hypothalamic proopiomelanocortin system during morphine tolerance.
Topics: Animals; beta-Endorphin; Drug Tolerance; Endorphins; Enkephalin, Methionine; Hypothalamus; Male; Morphine; Pro-Opiomelanocortin; Rats | 1986 |
Conversion and inactivation of opioid peptides by rabbit brain endo-oligopeptidase A.
Topics: Amino Acids; Animals; Bradykinin; Brain; Chromatography, High Pressure Liquid; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Hydrolysis; Peptide Fragments; Peptidyl-Dipeptidase A; Protein Precursors; Rabbits | 1985 |
Angiotensin-converting enzyme inhibitors potentiate the analgesic activity of [Met]-enkephalin-Arg6-Phe7 by inhibiting its degradation in mouse brain.
Topics: Analgesics; Angiotensin-Converting Enzyme Inhibitors; Animals; Brain; Captopril; Enalapril; Enalaprilat; Enkephalin, Methionine; Hydrolysis; In Vitro Techniques; Male; Mice; Mice, Inbred Strains; Peptidyl-Dipeptidase A; Synaptic Membranes; Thiorphan; Tiopronin | 1985 |
Opioid activity of pro-enkephalin-derived peptides in mouse vas deferens and guinea pig ileum.
Topics: Animals; Endorphins; Enkephalin, Methionine; Enkephalins; Guinea Pigs; Ileum; Male; Mice; Myenteric Plexus; Peptides; Protein Precursors; Receptors, Opioid; Vas Deferens | 1985 |
Hydrolysis of neo-kyotorphin (Thr-Ser-Lys-Tyr-Arg) and [Met]enkephalin-Arg6-Phe7 by angiotensin-converting enzyme from monkey brain.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Brain; Chromatography, High Pressure Liquid; Endorphins; Enkephalin, Methionine; Hydrolysis; Kinetics; Macaca fascicularis; Peptidyl-Dipeptidase A | 1986 |
Secretion of [Met]enkephalyl-Arg6-Phe7-related peptides and catecholamines from bovine adrenal chromaffin cells: modification by changes in cyclic AMP and by treatment with reserpine.
Topics: Adrenal Medulla; Animals; Bucladesine; Cattle; Cells, Cultured; Chromatography, Gel; Colforsin; Cyclic AMP; Enkephalin, Methionine; Epinephrine; Nicotine; Norepinephrine; Potassium; Reserpine | 1987 |
[Met]enkephalin-Arg6-Phe7 in human CSE--increased levels in late pregnancy.
Topics: Chromatography, High Pressure Liquid; Enkephalin, Methionine; Female; Humans; Luteal Phase; Pregnancy; Pregnancy Trimester, Third; Radioimmunoassay; Reference Values | 1986 |
The effects of opioid and FMRF-amide peptides on thermal behavior in the snail.
Topics: Animals; beta-Endorphin; Body Temperature; Body Temperature Regulation; Dose-Response Relationship, Drug; Endorphins; Enkephalin, Methionine; Humans; Morphine; Naloxone; Snails; Stereotyped Behavior | 1985 |
[Met5]enkephalin-Arg6-Phe7- and [Met5]enkephalin-Arg6-Gly7-Leu8-immunoreactive nerve fibres and neurons in the superior cervical ganglion of the rat.
Topics: Animals; Autonomic Fibers, Preganglionic; Cells, Cultured; Enkephalin, Methionine; Female; Ganglia, Sympathetic; Immunologic Techniques; Male; Microscopy, Electron; Rats; Rats, Inbred Strains; Spinal Cord | 1987 |
Proenkephalin A-derived peptides in the human gut.
Topics: Chromatography, High Pressure Liquid; Enkephalin, Leucine; Enkephalin, Methionine; Humans; Intestinal Mucosa; Intestines | 1988 |
Proenkephalin A processing in the upper digestive tract: isolation and characterisation of phosphorylated N-terminally extended Met-enkephalin Arg6Phe7 variants.
Topics: Alkaline Phosphatase; Amino Acid Sequence; Animals; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Duodenum; Enkephalin, Methionine; Enkephalins; Gastric Mucosa; Molecular Sequence Data; Phosphorylation; Protein Precursors; Pyloric Antrum; Radioimmunoassay; Swine | 1988 |
Separation of carboxypeptidase A and B from longitudinal muscle layer of bovine small intestine: their properties regarding hydrolysis of enkephalins and enkephalin-analogs.
Topics: Animals; Carboxypeptidase B; Carboxypeptidases; Carboxypeptidases A; Cattle; Enkephalin, Leucine; Enkephalin, Methionine; Intestine, Small; Kinetics; Myenteric Plexus | 1987 |
Immunocytochemical localization of proenkephalin-derived peptides in the central nervous system of the rat.
Topics: Animals; Brain; Enkephalin, Methionine; Enkephalins; Hypothalamus; Immunoenzyme Techniques; Mesencephalon; Neurons; Pituitary Gland, Posterior; Protein Precursors; Rats; Rats, Inbred Strains; Spinal Cord; Telencephalon; Thalamus | 1986 |
Distribution and development of proenkephalin-like immunoreactivity in the lumbar spinal cord of the chicken.
Topics: Animals; Chemical Phenomena; Chemistry; Chickens; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; Immunoenzyme Techniques; Protein Precursors; Spinal Cord | 1986 |
Effect of endogenous opioid peptides on acetylcholine release from the cat superior cervical ganglion: selective effect of a heptapeptide.
Topics: Acetylcholine; Animals; Cats; Endorphins; Enkephalin, Methionine; Enkephalins; Female; Ganglia, Sympathetic; Male | 1987 |
Identification of a proenkephalin precursor in striatal tissue.
Topics: Animals; Chromatography, Gel; Corpus Striatum; Enkephalin, Methionine; Enkephalins; Guinea Pigs; Isoelectric Focusing; Male; Molecular Weight; Protein Precursors; Radioimmunoassay; Rats; Rats, Inbred Strains | 1985 |
Cardiovascular activities of intravenous methionine-enkephalin-Arg6-Phe7 and methionine-enkephalin-Arg6-Gly7-Leu8 in the conscious dog.
Topics: Animals; Blood Pressure; Cardiovascular System; Dogs; Endopeptidases; Enkephalin, Methionine; Heart Rate; Naloxone; Structure-Activity Relationship | 1985 |
Histamine-immunoreactive endocrine cells in the adrenal medulla of the rat.
Topics: Adrenal Medulla; Animals; Dopamine beta-Hydroxylase; Enkephalin, Methionine; Fluorescent Antibody Technique; Histamine; Phenylethanolamine N-Methyltransferase; Rats; Serotonin | 1985 |
[Met-enkephalin-Arg6-Phe7 like immunoreactive substances in periaqueductal gray of the rabbit have an analgesic effect and participate in electroacupuncture analgesia].
Topics: Acupuncture Therapy; Adjuvants, Immunologic; Animals; Captopril; Electric Stimulation Therapy; Enkephalin, Methionine; Immune Sera; Periaqueductal Gray; Rabbits; Transcutaneous Electric Nerve Stimulation | 1985 |
Occurrence of met-enkephalin, met-enkephalin-Arg6-Phe7 and met-enkephalin-Arg6-Gly7-Leu8 in gastrin cells of hog antral mucosa.
Topics: Animals; Enkephalin, Methionine; Gastric Mucosa; Gastrins; Histocytochemistry; Pyloric Antrum; Swine | 1985 |
Ontogenesis of proenkephalin products in rat striatum and the inhibitory effects of low-level lead exposure.
Topics: Animals; Corpus Striatum; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; Female; Lead Poisoning; Pregnancy; Rats | 1985 |
Metorphamide, a C-terminally amidated opioid peptide, in human adrenal and human phaeochromocytoma.
Topics: Adrenal Gland Neoplasms; Adrenal Glands; Chromatography, Gas; Chromatography, Gel; Chromatography, High Pressure Liquid; Enkephalin, Methionine; Humans; Pheochromocytoma; Radioimmunoassay | 1985 |
Age-related and diurnal changes in Met5-Enk-Arg6-Phe7 and Met5-enkephalin contents of pituitary and rat brain structures.
Topics: Age Factors; Animals; beta-Endorphin; Brain; Chromatography, High Pressure Liquid; Circadian Rhythm; Endorphins; Enkephalin, Methionine; Female; Male; Pituitary Gland; Pregnancy; Rats; Rats, Inbred Strains; Tissue Distribution | 1984 |
Inhibition of the cardiac response to sympathetic nerve stimulation by opioid peptides and its potentiation by morphine and methadone.
Topics: Animals; beta-Endorphin; Drug Synergism; Electric Stimulation; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Guinea Pigs; Heart; In Vitro Techniques; Male; Methadone; Morphine; Myocardial Contraction; Norepinephrine; Sympathetic Nervous System | 1984 |
Multiple actions of a molluscan cardioexcitatory neuropeptide and related peptides on identified Helix neurones.
Topics: Animals; Calcium; Enkephalin, Methionine; FMRFamide; Helix, Snails; Ion Channels; Membrane Potentials; Nerve Tissue Proteins; Neural Conduction; Neurons; Oligopeptides; Potassium; Sodium; Tetraethylammonium; Tetraethylammonium Compounds | 1984 |
Kappa 3: a novel subtype of the kappa opioid site in bovine adrenal medulla, highly selective for Met-enkephalin-Arg6-Phe7.
Topics: Adrenal Medulla; Animals; Cattle; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Etorphine; In Vitro Techniques; Narcotics; Receptors, Opioid; Receptors, Opioid, kappa | 1984 |
The preference of putative pro-enkephalins for different types of opiate receptors.
Topics: Animals; Benzomorphans; Brain; Drug Tolerance; Dynorphins; Endorphins; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Enkephalins; Fentanyl; Guinea Pigs; Ileum; Male; Mice; Morphine; Protein Precursors; Rats; Receptors, Opioid; Vas Deferens | 1981 |
Characterization of enkephalins and related peptides in rat hypophysial portal blood.
Topics: Animals; Chromatography, Gel; Chromatography, High Pressure Liquid; Dynorphins; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; Male; Peptide Fragments; Pituitary Gland; Radioimmunoassay; Rats; Rats, Inbred Strains | 1984 |
Subcellular distribution of opioid peptides in rat hypothalamus and pituitary.
Topics: Animals; Arginine Vasopressin; Centrifugation, Density Gradient; Dynorphins; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Hypothalamus; Male; Peptide Fragments; Pituitary Gland; Protein Precursors; Rats; Rats, Inbred Strains; Subcellular Fractions; Synaptic Vesicles; Synaptosomes | 1984 |
Substance P stimulates the release of Met5-enkephalin-Arg6-Phe7 and Met5-enkephalin from rat spinal cord.
Topics: Animals; Enkephalin, Methionine; In Vitro Techniques; Male; Rats; Rats, Inbred Strains; Spinal Cord; Substance P | 1983 |
The effect of peptidase inhibitors on the release of Met5-Enk-Arg6-Phe7 (YGGFMRF) and Met5-enkephalin (YGGFM) from spinal cord induced by substance P in vivo.
Topics: Animals; Enkephalin, Methionine; Male; Protease Inhibitors; Rats; Rats, Inbred Strains; Spinal Cord; Substance P | 1983 |
Immunocytochemical demonstration of the co-storage of noradrenaline with Met-enkephalin-Arg6-Phe7 and Met-enkephalin-Arg6-Gly7-Leu8 in the carotid body chief cells of the dog.
Topics: Adrenal Medulla; Animals; Carotid Body; Catecholamines; Cytoplasmic Granules; Dogs; Enkephalin, Methionine; Epinephrine; Female; Histocytochemistry; Immunoenzyme Techniques; Male; Norepinephrine; Staining and Labeling | 1983 |
Action of peptidase inhibitors on methionine5-enkephalin-arginine6-phenylalanine7 (YGGFMRF) and methionine5-enkephalin (YGGFM) metabolism and on electroacupuncture antinociception.
Topics: Acupuncture Therapy; Analgesia; Animals; Captopril; Electronarcosis; Enkephalin, Methionine; Leucine; Male; Perfusion; Protease Inhibitors; Rats; Rats, Inbred Strains; Spinal Cord; Substance P; Thiorphan; Tiopronin | 1984 |
Location of substance P-, bombesin-gastrin-releasing peptide, [Met5]enkephalin- and [Met5]enkephalin-Arg6-Phe7-like immunoreactivities in adult human sympathetic ganglia.
Topics: Enkephalin, Methionine; Fluorescent Antibody Technique; Ganglia, Sympathetic; Gastrin-Releasing Peptide; Humans; Peptides; Substance P | 1984 |
A reduction of the tone of 5-hydroxytryptamine neurons decreases utilization rates of striatal and hypothalamic enkephalins.
Topics: 5,7-Dihydroxytryptamine; Animals; Corpus Striatum; Enkephalin, Methionine; Enkephalins; Fenclonine; Fenfluramine; Hypothalamus; Male; Neurons; Rats; Rats, Inbred Strains; Serotonin | 1984 |
Opioid hexapeptides and heptapeptides in adrenal medulla and brain possible implications on the biosynthesis of enkephalins.
Topics: Adrenal Medulla; Amino Acids; Animals; Brain Chemistry; Cattle; Cell Line; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; Glioma; Hybrid Cells; Neuroblastoma; Receptors, Opioid | 1980 |
Met-enkephalin[Arg6,Phe7] interacts with the kappa-receptors on guinea-pig ileum.
Topics: Animals; Dose-Response Relationship, Drug; Endorphins; Enkephalin, Methionine; Enkephalins; Guinea Pigs; Ileum; Naloxone; Receptors, Opioid | 1980 |
Mammalian neuronal actions of FMRFamide and the structurally related opioid Met-enkephalin-Arg6-Phe7.
Topics: Action Potentials; Animals; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; FMRFamide; Male; Medulla Oblongata; Naloxone; Neurons, Efferent; Oligopeptides; Rats; Rats, Inbred Strains; Receptors, Opioid | 1982 |
[Met5]enkephalin-Arg-Phe ACTS on vascular opiate receptors.
Topics: Animals; Cyclazocine; Electric Stimulation; Endorphins; Enkephalin, Methionine; Enkephalins; Ethylketocyclazocine; In Vitro Techniques; Muscle Contraction; Muscle, Smooth, Vascular; Rabbits; Receptors, Opioid | 1982 |
Met5-enkephalin-arg6-phe7 and its receptor in lung.
Topics: Animals; Binding, Competitive; Chromatography, Gel; Chromatography, High Pressure Liquid; Enkephalin, Methionine; Etorphine; Guinea Pigs; Humans; In Vitro Techniques; Lung; Male; Radioimmunoassay; Rats; Rats, Inbred Strains; Receptors, Opioid | 1983 |
The heptapeptide Met-enkephalin-Arg6, Phe7 is released from rat striatum in vitro by high potassium.
Topics: Animals; Calcium; Corpus Striatum; Culture Techniques; Enkephalin, Leucine; Enkephalin, Methionine; Potassium; Rats; Synaptic Transmission | 1983 |
Distribution of enkephalin-related peptides in rat brain: immunohistochemical studies using antisera to met-enkephalin and met-enkephalin Arg6Phe7.
Topics: Animals; Brain; Brain Stem; Diencephalon; Enkephalin, Methionine; Fluorescent Antibody Technique; Neurons; Rats; Rats, Inbred Strains; Spinal Cord; Synaptic Transmission; Telencephalon | 1983 |
Met5-enkephalin-Arg6-Phe7 inhibition of noradrenaline and acetylcholine release from peripheral organs.
Topics: Acetylcholine; Animals; Autonomic Nervous System; Axons; Electric Stimulation; Enkephalin, Methionine; Guinea Pigs; Ileum; In Vitro Techniques; Male; Mice; Muscle, Smooth; Neuroeffector Junction; Norepinephrine; Synaptic Transmission; Vas Deferens | 1984 |
Met5-enkephalin-arg6-phe7 content of human and rabbit plasma.
Topics: Adult; Animals; Captopril; Chromatography, Gel; Chromatography, High Pressure Liquid; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Enkephalin, Methionine; Female; Half-Life; Humans; Male; Middle Aged; Rabbits | 1983 |
Immunohistochemical studies on the gastrointestinal tract using antisera to Met-enkephalin and Met-enkephalin Arg6Phe7.
Topics: Animals; Antibody Specificity; Digestive System; Enkephalin, Methionine; Fluorescent Antibody Technique; Gastric Mucosa; Guinea Pigs; Histocytochemistry; Immune Sera; Intestinal Mucosa; Mice; Myenteric Plexus; Neurons; Rats; Submucous Plexus | 1983 |
Increase of striatal Met5-enkephalin-Arg6-Phe7 (YGGFMRF) content elicited by long-term treatment with haloperidol.
Topics: Animals; Captopril; Corpus Striatum; Enkephalin, Methionine; Haloperidol; Male; Rats; Rats, Inbred Strains; Time Factors; Tissue Distribution | 1984 |
Immunohistochemical evidence for preproenkephalin A synthesis in human retinoblastoma.
Topics: Cells, Cultured; Enkephalin, Methionine; Enkephalins; Eye Neoplasms; Female; Fluorescent Antibody Technique; Humans; Infant; Microscopy, Fluorescence; Protein Precursors; Retinoblastoma | 1984 |
Co-storage of adrenaline and noradrenaline with Met-enkephalin-Arg6-Gly7-Leu8 and Met-enkephalin-Arg6-Phe7 in chromaffin cells of hamster adrenal medulla.
Topics: Adrenal Medulla; Animals; Cricetinae; Enkephalin, Methionine; Epinephrine; Female; Histocytochemistry; Immunoenzyme Techniques; Male; Mesocricetus; Norepinephrine | 1984 |
Met-enkephalin-Arg6-Phe7-like immunoreactive substances mediate electroacupuncture analgesia in the periaqueductal gray of the rabbit.
Topics: Acupuncture Therapy; Animals; Brain Mapping; Captopril; Combined Modality Therapy; Electric Stimulation Therapy; Enkephalin, Methionine; Male; Naloxone; Pain; Pain Management; Periaqueductal Gray; Rabbits | 1984 |
Effect of bestatin and thiorphan on [Met5]enkephalin-Arg6-Phe7-induced analgesia.
Topics: Amino Acids, Sulfur; Aminopeptidases; Analgesia; Animals; Enkephalin, Methionine; Leucine; Male; Neprilysin; Protease Inhibitors; Rats; Rats, Inbred Strains; Thiorphan; Tiopronin | 1984 |
Immunohistochemical localization of unique enkephalin sequences contained in preproenkephalin A in the guinea pig cochlea.
Topics: Animals; Cochlea; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; Fluorescent Antibody Technique; Guinea Pigs; Hair Cells, Auditory; Hair Cells, Auditory, Inner; Organ of Corti; Protein Precursors; Spiral Ganglion | 1984 |
Localization of Met5-enkephalin-Arg6-Phe7-like immunoreactivity in the rat gastrointestinal tract.
Topics: Animals; Digestive System; Enkephalin, Methionine; Female; Fluorescent Antibody Technique; Male; Myenteric Plexus; Rats; Rats, Inbred Strains; Submucous Plexus | 1984 |
Demonstration and characterization of immunoreactive methionine-enkephalin, leucine-enkephalin, methionine-enkephalin-Arg6-Gly7-Leu8 and methionine-enkephalin-Arg6-Phe7 in human phaeochromocytoma.
Topics: Adolescent; Adrenal Gland Neoplasms; Adult; Aged; Chromatography, Gel; Chromatography, High Pressure Liquid; Enkephalin, Leucine; Enkephalin, Methionine; Female; Humans; Male; Middle Aged; Pheochromocytoma; Radioimmunoassay | 1984 |
Characterisation of Met-enkephalin(Arg6,Phe7) immunoreactivity in human adrenal and human phaeochromocytoma.
Topics: Adrenal Gland Neoplasms; Adrenal Glands; Adult; Catecholamines; Child; Chromatography, Gel; Chromatography, High Pressure Liquid; Enkephalin, Methionine; Humans; Immune Sera; Male; Middle Aged; Pheochromocytoma; Radioimmunoassay; Subcellular Fractions | 1984 |
Processing of proenkephalin is tissue-specific.
Topics: Adrenal Medulla; Animals; Cattle; Enkephalin, Methionine; Enkephalins; Hypothalamus; Organ Specificity; Pituitary Gland, Posterior; Protein Precursors; Supraoptic Nucleus | 1984 |
[Opioid peptides in the tooth pulp].
Topics: Animals; Dental Cavity Preparation; Dental Pulp; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Enzyme Activation; Rats; Trypsin | 1983 |
The conversion of Met-enkephalin-Arg6, Phe7 to Met-enkephalin in rabbit ear artery.
Topics: Animals; Arteries; Biological Assay; Ear; Enkephalin, Methionine; Rabbits | 1983 |
Release of the heptapeptide Met-enkephalin-Arg6-Phe7 and of the octapeptide Met-enkephalin-Arg6-Gly7-Leu8 from rat striatum in vitro and their rapid inactivation.
Topics: Animals; Calcium; Corpus Striatum; Enkephalin, Methionine; In Vitro Techniques; Kinetics; Potassium; Rats | 1983 |
Proenkephalin-A-derived peptides are present in human brain.
Topics: Brain Chemistry; Chromatography, High Pressure Liquid; Enkephalin, Methionine; Humans; Protein Precursors; Radioimmunoassay; Tissue Distribution | 1983 |
Parallel distribution of methionine-enkephalin-Arg6-Gly7-Leu8 with methionine-enkephalin, leucine-enkephalin and methionine-enkephalin-Arg6-Phe7 in human and bovine brains.
Topics: Animals; Brain Chemistry; Cattle; Chromatography, High Pressure Liquid; Enkephalin, Leucine; Enkephalin, Methionine; Humans; Species Specificity | 1983 |
Isolation of molluscan opioid peptides.
Topics: Animals; Bivalvia; Chromatography, High Pressure Liquid; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Ganglia | 1983 |
Met-enkephalin-Arg6-Gly7-Leu8 exists together with Met-enkephalin-Arg6-Phe7, Met-enkephalin and Leu-enkephalin in human stomach.
Topics: Chromatography, Gel; Chromatography, High Pressure Liquid; Enkephalin, Leucine; Enkephalin, Methionine; Humans; Pyloric Antrum; Radioimmunoassay | 1983 |
Methionine-enkephalin, leucine-enkephalin methionine-enkephalin-Arg6-Phe7 and methionine-enkephalin-Arg6-Gly7-Leu8 in human pheochromocytoma.
Topics: Adrenal Gland Neoplasms; Chromatography, Gel; Chromatography, High Pressure Liquid; Enkephalin, Leucine; Enkephalin, Methionine; Humans; Pheochromocytoma; Radioimmunoassay | 1983 |
Regional distribution of methionine-enkephalin-Arg6-Phe7 in the rat brain: comparative study with the distribution of other opioid peptides.
Topics: Amino Acid Sequence; Animals; Brain Chemistry; Chromatography, High Pressure Liquid; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; Male; Pituitary Hormones, Anterior; Pro-Opiomelanocortin; Protein Precursors; Radioimmunoassay; Rats; Rats, Inbred Strains; Tissue Distribution | 1983 |
Presence of Met-enkephalin-Arg6-Phe7 in molluscan neural tissues.
Topics: Animals; Bivalvia; Chromatography, High Pressure Liquid; Enkephalin, Methionine; Ganglia; Neurons | 1984 |
Enkephalin heptapeptide (Tyr-Gly-Gly-Phe-Met-Arg-Phe)-induced bronchospasm in guinea pigs: a non-naloxone reversible phenomenon.
Topics: Animals; Bronchi; Chromones; Dose-Response Relationship, Drug; Enkephalin, Methionine; Guinea Pigs; Ibuprofen; Imidazoles; Male; Naloxone; Pressure; Trachea; Vagotomy | 1984 |
Evidence for different patterns of post-translational processing of pro-enkephalin in the bovine adrenal, colon and striatum indicated by radioimmunoassay using region-specific antisera to Met-Enk-Arg6-Phe7 and Met-Enk-Arg6-Gly7-Leu8.
Topics: Adrenal Glands; Animals; Cattle; Colon; Corpus Striatum; Enkephalin, Methionine; Enkephalins; Organ Specificity; Protein Precursors; Radioimmunoassay | 1984 |
Distribution and characterization of opioid peptides derived from proenkephalin A in human and rat central nervous system.
Topics: Adolescent; Adult; Aged; Animals; Brain; Enkephalin, Methionine; Enkephalins; Female; Humans; Male; Middle Aged; Peptides; Pituitary Gland; Protein Precursors; Rats; Rats, Inbred Strains; Spinal Cord | 1984 |
Possible role of dipeptidyl carboxypeptidase n the metabolism of Met5-enkephalin and Met5-enkephalin-Arg6-Phe7.
Topics: Animals; Captopril; Cattle; Chlorides; Corpus Striatum; Endopeptidases; Enkephalin, Methionine; Neprilysin; Protease Inhibitors; Rats; Rats, Inbred Strains; Thiorphan; Tiopronin | 1982 |
Rat brain and kidney metalloendopeptidase: enkephalin heptapeptide conversion to form a cardioactive neuropeptide, Phe-Met-Arg-Phe-amide.
Topics: Animals; Brain; Endopeptidases; Enkephalin, Methionine; FMRFamide; Kidney; Metalloendopeptidases; Oligopeptides; Organ Specificity; Rats; Substrate Specificity | 1982 |
In vitro biosynthesis and processing of immunologically identified methionine-enkephalin precursor protein.
Topics: Animals; Antibody Specificity; Brain Chemistry; Chromatography, High Pressure Liquid; Dogs; Enkephalin, Methionine; Guinea Pigs; Immune Sera; Molecular Weight; Protein Biosynthesis; Protein Precursors; Rabbits | 1983 |
Characterization and location of Met5-enkephalin-arg6-phe7 stored in various rat brain regions.
Topics: Animals; Brain; Brain Chemistry; Cross Reactions; Enkephalin, Methionine; Immune Sera; Radioimmunoassay; Rats; Tissue Distribution | 1983 |
Occurrence of methionine-enkephalin-Arg6-Gly7-Leu8 with methionine-enkephalin, leucine-enkephalin and methionine-enkephalin-Arg6-Phe7 in human gastric antrum.
Topics: Adult; Chromatography, Gel; Chromatography, High Pressure Liquid; Enkephalin, Leucine; Enkephalin, Methionine; Humans; Pyloric Antrum; Radioimmunoassay | 1983 |
Distribution of Met5-enkephalin-Arg6, Phe7 in rat spinal cord.
Topics: Animals; Enkephalin, Methionine; Immune Sera; Male; Radioimmunoassay; Rats; Rats, Inbred Strains; Spinal Cord; Tissue Distribution | 1983 |
Modulation of nicotinic receptor function by opiate recognition sites highly selective for Met5-enkephalin[Arg6Phe7].
Topics: Acetylcholine; Adrenal Medulla; Animals; Binding Sites; Bungarotoxins; Cattle; Cell Membrane; Cells, Cultured; Diprenorphine; Dogs; Endorphins; Enkephalin, Methionine; Epinephrine; Etorphine; Norepinephrine; Receptors, Cholinergic; Receptors, Nicotinic; Splanchnic Nerves | 1983 |
Analgesic activity of the naturally occurring heptapeptide [Met]enkephalin-Arg6-Phe7.
Topics: Analgesics; Animals; Diarrhea; Diuresis; Dose-Response Relationship, Drug; Endorphins; Enkephalin, Methionine; Enkephalins; Injections, Intravenous; Injections, Intraventricular; Male; Mice; Naloxone; Rats | 1980 |
Met-enkephalin-Arg6-Phe7 metabolism: conversion to Met-enkephalin by brain and kidney dipeptidyl carboxypeptidases.
Topics: Amino Acid Sequence; Animals; Brain; Endopeptidases; Endorphins; Enkephalin, Methionine; Enkephalins; Kidney; Kinetics; Mitochondria; Oligopeptides; Rabbits | 1981 |
Conversion of [met5]-enkephalin-Arg6-Phe7 to [met5]-enkephalin by dipeptidyl carboxypeptidase.
Topics: Animals; Brain Chemistry; Cattle; Corpus Striatum; Endopeptidases; Endorphins; Enkephalin, Methionine; Enkephalins; In Vitro Techniques; Microsomes; Pregnenediones; Steroids, Chlorinated | 1981 |
Differential distribution in rat basal ganglia of Met-enkephalin- and Met-enkephalin Arg6 Phe7-like peptides revealed by immunohistochemistry.
Topics: Animals; Basal Ganglia; Caudate Nucleus; Endorphins; Enkephalin, Methionine; Enkephalins; Fluorescent Antibody Technique; Globus Pallidus; Histocytochemistry; Male; Peptides; Putamen; Rats; Rats, Inbred Strains; Tissue Distribution | 1982 |
Met-enkephalin [Arg6, Phe7] immunoreactivity in bovine caudate and bovine adrenal medulla.
Topics: Adrenal Medulla; Animals; Antibody Specificity; Cattle; Caudate Nucleus; Chromaffin Granules; Chromatography, Gel; Chromatography, High Pressure Liquid; Endorphins; Enkephalin, Methionine; Enkephalins; Radioimmunoassay | 1982 |
Measurement of methionine-enkephalin [Arg6,Phe7] in rat brain by specific radioimmunoassay directed at methionine sulphoxide enkephalin[Arg6,Phe7].
Topics: Animals; Brain Chemistry; Corpus Striatum; Cross Reactions; Endorphins; Enkephalin, Methionine; Enkephalins; Radioimmunoassay; Rats; Tissue Distribution | 1982 |
Distribution of met-enkephalin-Arg6-Phe7 in various tissues of rats and guinea pigs.
Topics: Adrenal Glands; Animals; Endorphins; Enkephalin, Methionine; Enkephalins; Ganglia, Sympathetic; Gastric Mucosa; Guinea Pigs; Intestinal Mucosa; Liver; Lung; Male; Myocardium; Pancreas; Rats; Rats, Inbred Strains | 1982 |
Conversion of Met-enkephalin-Arg-Phe by brain carboxypeptidases and by membrane fractions.
Topics: Animals; Biotransformation; Brain; Carboxypeptidases; Cell Membrane; Central Nervous System; Enkephalin, Methionine; In Vitro Techniques; Kinetics; Rats; Synaptosomes; Time Factors | 1982 |
Existence of Met-enkephalin-Arg6-Gly7-Leu8 with Met-enkephalin, Leu-enkephalin and Met-enkephalin-Arg6-Phe7 in the brain of guinea pig, rat and golden hamster.
Topics: Animals; Brain Chemistry; Chromatography, High Pressure Liquid; Cricetinae; Enkephalin, Leucine; Enkephalin, Methionine; Guinea Pigs; Mesocricetus; Radioimmunoassay; Rats; Species Specificity | 1982 |
Blood pressure elevation in rats by peripheral administration of Tyr-Gly-Gly-Phe-Met-Arg-Phe and the invertebrate neuropeptide, Phe-Met-Arg-Phe-NH2.
Topics: Animals; Blood Pressure; Enkephalin, Methionine; FMRFamide; Heart Rate; Injections, Intravenous; Male; Oligopeptides; Rats; Rats, Inbred Strains; Respiration; Stereoisomerism; Stimulation, Chemical; Vascular Resistance | 1982 |
Enkephalin congeners and precursors are synthesized and released by primary cultures of adrenal chromaffin cells.
Topics: Adrenal Medulla; Animals; Cattle; Cells, Cultured; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; Nicotine; Protein Precursors | 1981 |
Conversion of Met-enkephalin-Arg6-Phe7 by a purified brain carboxypeptidase (cathepsin A).
Topics: Amino Acid Sequence; Animals; Brain; Carboxypeptidases; Cathepsin A; Cathepsins; Endorphins; Enkephalin, Methionine; Enkephalins; Kinetics; Rats; Substrate Specificity | 1981 |
[The content of dynorphin, Met-enk-Arg6-Phe7 and substance P (1-11) in the brain of mice with different levels of ethanol consumption].
Topics: Alcohol Drinking; Analysis of Variance; Animals; Brain Chemistry; Corpus Striatum; Dynorphins; Enkephalin, Methionine; Hippocampus; Mice; Mice, Inbred A; Mice, Inbred C57BL; Peptide Fragments; Radioimmunoassay; Species Specificity; Spinal Cord; Substance P | 1993 |
Substrate- and inhibitor-specificity of a non-endothelial enzyme which forms [Met5]-enkephalin from [Met5]-enkephalin-Arg6,Phe7 in isolated rabbit ear artery: pharmacological characterization.
Topics: Amino Acid Sequence; Angiotensin I; Animals; Arteries; Bradykinin; Captopril; Disease Models, Animal; Ear, External; Enalapril; Endopeptidases; Endothelium, Vascular; Enkephalin, Methionine; Male; Migraine Disorders; Molecular Sequence Data; Rabbits; Substrate Specificity; Thiorphan | 1995 |
Intrinsic cardiac enkephalins inhibit vagal bradycardia in the dog.
Topics: Animals; Bradycardia; Diprenorphine; Dogs; Dose-Response Relationship, Drug; Electric Stimulation; Enkephalin, Methionine; Heart Rate; Methacholine Chloride; Myocardium; Vagus Nerve | 1995 |
Nitrous oxide selectively releases Met5-enkephalin and Met5-enkephalin-Arg6-Phe7 into canine third ventricular cerebrospinal fluid.
Topics: Analgesia; Animals; beta-Endorphin; Chromatography, High Pressure Liquid; Dogs; Dynorphins; Enkephalin, Methionine; Female; Male; Nitrous Oxide; Radioimmunoassay | 1995 |
Characterization of [3H]Met-enkephalin-Arg6-Phe7 binding to opioid receptors in frog brain membrane preparations.
Topics: Analgesics; Animals; Binding, Competitive; Brain; Cell Membrane; Enkephalin, Methionine; Kinetics; Radioligand Assay; Rana esculenta; Receptors, Opioid; Tritium | 1994 |
Antitussive effect of [Met5]enkephalin-Arg6-Phe7 in mice.
Topics: Animals; Antitussive Agents; Capsaicin; Cough; Dose-Response Relationship, Drug; Enkephalin, Methionine; Injections, Intraventricular; Male; Mice; Naltrexone; Narcotic Antagonists; Receptors, Opioid, kappa; Receptors, Opioid, mu | 1994 |
Fetal adrenalectomy does not affect circulating enkephalins in the sheep fetus during late gestation.
Topics: Adrenal Glands; Adrenalectomy; Animals; Enkephalin, Methionine; Enkephalins; Female; Femoral Artery; Fetal Blood; Fetus; Gestational Age; Norepinephrine; Pregnancy; Sheep; Umbilical Veins | 1993 |
Developmental changes in rat adrenal enkephalin precursor: peptide ratio.
Topics: Adrenal Glands; Aging; Animals; Carboxypeptidase H; Carboxypeptidases; Enkephalin, Methionine; Enkephalins; Nicotine; Protein Precursors; Rats; Rats, Inbred F344 | 1993 |
Methionine-enkephalin-Arg-Phe immunoreactivity in heart tissue.
Topics: Animals; Cats; Dogs; Enkephalin, Methionine; Fluorescent Antibody Technique; Heart Ventricles; Myocardium; Radioimmunoassay; Swine | 1995 |
Pericardial repair depresses canine cardiac catecholamines and met-enkephalin.
Topics: Animals; Catecholamines; Dogs; Enkephalin, Methionine; Epinephrine; Female; Heart Ventricles; Male; Myocardium; Norepinephrine; Pericardium; Sympathectomy | 1995 |
Met-enkephalin Arg-Phe-immunoreactive neurons in the central nervous system of the pond snail Lymnaea stagnalis.
Topics: Amino Acid Sequence; Animals; Antibodies; Central Nervous System; Cheek; Cross Reactions; Enkephalin, Methionine; Ganglia, Autonomic; Ganglia, Invertebrate; Immunohistochemistry; Lymnaea; Molecular Sequence Data; Neurons; Radioimmunoassay | 1996 |
Hemorrhage alters plasma and cardiac enkephalins and catecholamines in anesthetized dogs.
Topics: Animals; Catecholamines; Chromatography; Dogs; Enkephalin, Methionine; Enkephalins; Hemorrhage; Hypotension; Myocardium; Peptides; Protein Precursors | 1995 |
Conformational study of [Met5]enkephalin-Arg-Phe in the presence of phosphatidylserine vesicles.
Topics: Amino Acid Sequence; Circular Dichroism; Enkephalin, Methionine; Liposomes; Magnetic Resonance Spectroscopy; Molecular Structure; Phosphatidylserines; Protein Conformation; Thermodynamics | 1996 |
Neutral endopeptidase activity in breast cysts.
Topics: Breast Neoplasms; Enkephalin, Methionine; Female; Fibrocystic Breast Disease; Humans; Leucyl Aminopeptidase; Neprilysin; Oligopeptides; Spectrometry, Fluorescence; Substrate Specificity | 1996 |
Dexamethasone and forskolin synergistically increase [Met5]enkephalin accumulation in mixed brain cell cultures.
Topics: Animals; Astrocytes; Brain; Cells, Cultured; Colforsin; Dexamethasone; Drug Combinations; Drug Synergism; Enkephalin, Methionine; Enkephalins; Glucocorticoids; Neuroglia; Neurons; Protein Precursors; Rats; Rats, Inbred F344; Receptors, Glucocorticoid; RNA, Messenger | 1996 |
Plasma catecholamine and met-enkephalin-Arg6-Phe7 responses to hypoxaemia after adrenalectomy in the fetal sheep.
Topics: Adrenalectomy; Animals; Asphyxia; Blood Gas Analysis; Enkephalin, Methionine; Epinephrine; Female; Fetus; Hypoxia; Male; Norepinephrine; Pregnancy; Sheep | 1996 |
Met5-enkephalin-Arg6-Phe7, an endogenous neuropeptide, binds to multiple opioid and nonopioid sites in rat brain.
Topics: Animals; Binding Sites; Binding, Competitive; Brain; Chromatography, High Pressure Liquid; Enkephalin, Methionine; FMRFamide; Guanylyl Imidodiphosphate; Membranes; Neuropeptides; Rats; Receptors, Opioid; Sodium | 1997 |
Differences in the hydrolysis of enkephalin congeners by the two domains of angiotensin converting enzyme.
Topics: Analgesics, Opioid; Binding Sites; Chlorides; Chromatography, High Pressure Liquid; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Enkephalins; Humans; Hydrogen-Ion Concentration; Hydrolysis; In Vitro Techniques; Kinetics; Peptidyl-Dipeptidase A | 1997 |
Resting membrane properties of locust muscle and their modulation I. Actions of the neuropeptides YGGFMRFamide and proctolin.
Topics: Animals; Chelating Agents; Collagenases; Egtazic Acid; Electric Conductivity; Enkephalin, Methionine; Grasshoppers; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Iontophoresis; Membrane Potentials; Motor Neurons; Muscles; Neuropeptides; Neurotransmitter Agents; Oligopeptides; Patch-Clamp Techniques; Potassium; Potassium Channels; Second Messenger Systems | 1998 |
[Modulation of the antiarrhythmic effect by endogenous opioids during adaptation to hypoxia in rats].
Topics: Adaptation, Physiological; Animals; Arrhythmias, Cardiac; Enkephalin, Methionine; Hypothalamus; Hypoxia; Ligands; Narcotic Antagonists; Rats; Rats, Wistar; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu | 1998 |
Diurnal variations of opioid peptides and synenkephalin in vitro release in the amygdala of kindled rats.
Topics: Amygdala; Animals; Circadian Rhythm; Convulsants; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; In Vitro Techniques; Injections, Intraperitoneal; Kindling, Neurologic; Male; Opioid Peptides; Pentylenetetrazole; Protein Precursors; Rats; Rats, Wistar | 1998 |
Characterization of [3H]Met-enkephalin-Arg6-Phe7 binding to multiple sites in rat and guinea pig cerebellum.
Topics: Animals; Binding Sites; Binding, Competitive; Cerebellum; Enkephalin, Methionine; Guinea Pigs; Naloxone; Rats; Rats, Wistar; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, sigma; Species Specificity | 1999 |
Irreversible labelling of the opioid receptors by a melphalan-substituted [Met5]enkephalin-Arg-Phe derivative.
Topics: Affinity Labels; Amino Acid Sequence; Amino Acid Substitution; Animals; Binding Sites; Binding, Competitive; Brain; Enkephalin, Methionine; Female; Guinea Pigs; Male; Melphalan; Membranes; Naloxone; Naltrexone; Narcotic Antagonists; Radioligand Assay; Rats; Receptors, Opioid | 1999 |
Comparison of the endogenous heptapeptide Met-enkephalin-Arg6-Phe7 binding in amphibian and mammalian brain.
Topics: Animals; Binding Sites; Brain; Enkephalin, Methionine; Guinea Pigs; Humans; Protein Binding; Radioligand Assay; Rana esculenta; Rats | 1999 |
Met5-enkephalin protects isolated adult rabbit cardiomyocytes via delta-opioid receptors.
Topics: Animals; beta-Endorphin; Cell Hypoxia; Cells, Cultured; Enkephalin, Leucine; Enkephalin, Methionine; Heart; Ischemic Preconditioning; Male; Models, Cardiovascular; Morphine; Myocardial Ischemia; Myocardium; Naloxone; Rabbits; Rats; Receptors, Opioid, delta | 1999 |
Central changes in nociceptin dynorphin B and Met-enkephalin-Arg-Phe in different models of nociception.
Topics: Animals; Brain; Dynorphins; Efferent Pathways; Endorphins; Enkephalin, Methionine; Inflammation; Male; Nerve Crush; Nociceptin; Nociceptors; Opioid Peptides; Pain; Rats; Rats, Sprague-Dawley | 2000 |
The effect on opioid peptides in the rat brain, after chronic treatment with the anabolic androgenic steroid, nandrolone decanoate.
Topics: Anabolic Agents; Animals; Brain; Corpus Striatum; Dynorphins; Endorphins; Enkephalin, Methionine; Hypothalamus; Male; Nandrolone; Opioid Peptides; Periaqueductal Gray; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu | 2000 |
Receptor binding and G-protein activation by new Met5-enkephalin-Arg6-Phe7 derived peptides.
Topics: Animals; Brain; Enkephalin, Methionine; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanylyl Imidodiphosphate; Naloxone; Radioligand Assay; Rana esculenta; Rats; Receptors, Opioid, kappa | 2000 |
Receptor selectivity of Met-enkephalin-Arg6-Phe7, an endogenous opioid peptide, in cerebral cortex of human and rat.
Topics: Adult; Animals; Benzeneacetamides; Benzomorphans; Binding Sites; Cerebral Cortex; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Methionine; Ethylketocyclazocine; Female; Humans; Male; Naloxone; Naltrexone; Norepinephrine; Oligopeptides; Peptide Fragments; Peptides; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Somatostatin | 2000 |
Cardiac synthesis, processing, and coronary release of enkephalin-related peptides.
Topics: Animals; Coronary Vessels; Enkephalin, Methionine; Enkephalins; In Vitro Techniques; Male; Myocardium; Perfusion; Protein Precursors; Rats; Rats, Sprague-Dawley; Sympathectomy, Chemical; Time Factors | 2000 |
Basal levels and alcohol-induced changes in nociceptin/orphanin FQ, dynorphin, and enkephalin levels in C57BL/6J mice.
Topics: Alcohol Drinking; Alcohol-Induced Disorders, Nervous System; Animals; Brain; Brain Chemistry; Drug Administration Schedule; Dynorphins; Endorphins; Enkephalin, Methionine; Enkephalins; Ethanol; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Nociceptin; Opioid Peptides; Pituitary Gland; Self Administration | 2000 |
Repeated ethanol administration induces short- and long-term changes in enkephalin and dynorphin tissue concentrations in rat brain.
Topics: Animals; Brain; Brain Chemistry; Dynorphins; Endorphins; Enkephalin, Methionine; Ethanol; Hippocampus; Kinetics; Male; Nucleus Accumbens; Periaqueductal Gray; Rats; Rats, Sprague-Dawley | 2000 |
Local opiate receptors in the sinoatrial node moderate vagal bradycardia.
Topics: Animals; Blood Pressure; Bradycardia; Coronary Vessels; Diprenorphine; Dogs; Electric Stimulation; Enkephalin, Methionine; Enkephalins; Heart Rate; Narcotic Antagonists; Norepinephrine; Receptors, Opioid; Sinoatrial Node; Sympathomimetics; Vagus Nerve | 2001 |
Delta opioid receptors inhibit vagal bradycardia in the sinoatrial node.
Topics: Animals; Bradycardia; Dogs; Enkephalin, Methionine; Enkephalins; Microdialysis; Peptide Fragments; Protein Precursors; Receptors, Opioid, delta; Sinoatrial Node; Sympathomimetics; Vagus Nerve | 2001 |
Conditioned opioid withdrawal decreases nociceptin/orphanin FQ levels in the frontal cortex and olfactory tubercle.
Topics: Animals; Behavior, Animal; Conditioning, Psychological; Cues; Down-Regulation; Dynorphins; Electric Stimulation; Enkephalin, Methionine; Male; Naloxone; Narcotic Antagonists; Nociceptin; Olfactory Pathways; Opioid Peptides; Opioid-Related Disorders; Prefrontal Cortex; Rats; Rats, Wistar; Reinforcement, Psychology; Stress, Physiological; Substance Withdrawal Syndrome | 2002 |
Cardiac enkephalins interrupt vagal bradycardia via delta 2-opioid receptors in sinoatrial node.
Topics: Analgesics; Analgesics, Opioid; Animals; Benzylidene Compounds; Bradycardia; Dogs; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Methionine; Naltrexone; Narcotic Antagonists; Oligopeptides; Opioid Peptides; Quinolines; Receptors, Opioid, delta; Sinoatrial Node; Vagus Nerve | 2003 |
Behavioral and neuroendocrine actions of the Met-enkephalin-related peptide MERF.
Topics: Analysis of Variance; Animals; Behavior, Animal; Corticotropin-Releasing Hormone; Dopamine; Enkephalin, Methionine; Exploratory Behavior; Haloperidol; Hormone Antagonists; Hypothalamo-Hypophyseal System; Male; Mice; Motor Activity; Naloxone; Naltrexone; Narcotic Antagonists; Neostriatum; Organ Culture Techniques; Peptide Fragments; Pituitary-Adrenal System | 2003 |
Purification and quantification of opioid peptides in bone and joint tissues--a methodological study in the rat.
Topics: Animals; Bone and Bones; Chromatography, Ion Exchange; Dynorphins; Endorphins; Enkephalin, Methionine; Joints; Male; Radioimmunoassay; Rats; Rats, Inbred Lew; Reproducibility of Results | 2003 |
Long-term effects of short and long periods of maternal separation on brain opioid peptide levels in male Wistar rats.
Topics: Animals; Animals, Newborn; Behavior, Animal; Body Weight; Brain; Corticosterone; Dynorphins; Endorphins; Enkephalin, Methionine; Enkephalins; Female; Male; Maternal Deprivation; Opioid Peptides; Pituitary Gland; Protein Precursors; Radioimmunoassay; Rats; Rats, Wistar; Time Factors; Ultrasonics | 2003 |
Cardiac enkephalins attenuate vagal bradycardia: interactions with NOS-1-cGMP systems in canine sinoatrial node.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arginine; Bradycardia; Cyclic GMP; Dogs; Dose-Response Relationship, Drug; Enkephalin, Methionine; Enzyme Inhibitors; Indazoles; Methacholine Chloride; NG-Nitroarginine Methyl Ester; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Parasympathomimetics; Penicillamine; Phosphodiesterase Inhibitors; Sinoatrial Node; Vagus Nerve | 2003 |
Bimodal delta-opioid receptors regulate vagal bradycardia in canine sinoatrial node.
Topics: Animals; Bradycardia; Coronary Artery Disease; Coronary Circulation; Dogs; Dose-Response Relationship, Drug; Enkephalin, Methionine; Female; Male; Microdialysis; Parasympathetic Nervous System; Receptors, Opioid, delta; Sinoatrial Node; Stimulation, Chemical; Vagus Nerve | 2003 |
Production and characterization of antibodies for the specific determination of the opioid peptide Met5-Enkephalin-Arg6-Phe7.
Topics: Animals; Antibodies; Antibody Specificity; Chromatography, High Pressure Liquid; Enkephalin, Methionine; Female; Hypothalamus; Male; Opioid Peptides; Rabbits; Radioimmunoassay; Rats | 2004 |
Differential regulation of hippocampal progenitor proliferation by opioid receptor antagonists in running and non-running spontaneously hypertensive rats.
Topics: Adrenocorticotropic Hormone; Animals; Behavior, Animal; beta-Endorphin; Bromodeoxyuridine; Cell Division; Corticosterone; Enkephalin, Methionine; Female; Hippocampus; Motor Activity; Naltrexone; Narcotic Antagonists; Narcotics; Physical Conditioning, Animal; Radioimmunoassay; Random Allocation; Rats; Rats, Inbred SHR; Receptors, Opioid; Running | 2004 |
Maternal separation alters maternal care, but has minor effects on behavior and brain opioid peptides in adult offspring.
Topics: Animals; Brain; Corticosterone; Dynorphins; Emotions; Endorphins; Enkephalin, Methionine; Female; Male; Maternal Behavior; Maternal Deprivation; Motor Activity; Nesting Behavior; Rats; Reference Values; Social Behavior | 2004 |
Effects of maternal separation on voluntary ethanol intake and brain peptide systems in female Wistar rats.
Topics: Alcohol Drinking; Animals; Body Weight; Brain; Eating; Enkephalin, Methionine; Female; Male; Maternal Deprivation; Nociceptin; Opioid Peptides; Radioimmunoassay; Rats; Rats, Wistar; Time Factors | 2005 |
Ischemic preconditioning increases the bioavailability of cardiac enkephalins.
Topics: Animals; Coronary Circulation; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; In Vitro Techniques; Ischemic Preconditioning, Myocardial; Male; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion; Protein Precursors; Radioimmunoassay; Rats; Rats, Sprague-Dawley | 2005 |
Effect of starvation on Fos and neuropeptide immunoreactivities in the brain and pituitary gland of Xenopus laevis.
Topics: Animals; Appetite Regulation; Brain; Cell Size; Corticotropin-Releasing Hormone; Enkephalin, Methionine; Immunohistochemistry; Nerve Tissue Proteins; Neuropeptide Y; Neuropeptides; Pituitary Gland; Proto-Oncogene Proteins c-fos; Starvation; Urocortins; Ventral Thalamic Nuclei; Xenopus | 2006 |
Variations in opioid peptide levels during the estrous cycle in Sprague-Dawley rats.
Topics: Animals; Brain; Enkephalin, Methionine; Enkephalins; Estrous Cycle; Female; Opioid Peptides; Protein Precursors; Radioimmunoassay; Rats; Rats, Sprague-Dawley | 2006 |
Vagotonic effects of enkephalin are not mediated by sympatholytic mechanisms.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Dogs; Enkephalin, Methionine; Female; Heart Rate; Male; Naltrexone; Receptors, Opioid, kappa; Sympatholytics; Vagus Nerve | 2006 |
Met5-enkephalin-Arg6-Phe7 (MEAP): a cardioprotective hormonal opioid.
Topics: Animals; Cardiotonic Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Enkephalin, Methionine; Injections, Intramuscular; Myocardial Ischemia; Myocardial Reperfusion; Myocardial Reperfusion Injury; Rabbits; Random Allocation; Reference Values; Treatment Outcome | 2006 |
Repeated delta1-opioid receptor stimulation reduces delta2-opioid receptor responses in the SA node.
Topics: Analgesics; Analgesics, Opioid; Animals; Benzylidene Compounds; Bradycardia; Dogs; Dose-Response Relationship, Drug; Enkephalin, Methionine; Female; Male; Microdialysis; Naltrexone; Narcotic Antagonists; Oligopeptides; Quinolines; Receptors, Opioid, delta; Sinoatrial Node; Stimulation, Chemical; Vagus Nerve | 2006 |
The monosialosyl ganglioside GM-1 reduces the vagolytic efficacy of delta2-opioid receptor stimulation.
Topics: Analgesics, Opioid; Animals; Benzylidene Compounds; Bradycardia; Dogs; Dose-Response Relationship, Drug; Enkephalin, Methionine; Female; G(M1) Ganglioside; Male; Naltrexone; Narcotic Antagonists; Oligopeptides; Receptors, Opioid, delta; Sinoatrial Node; Stimulation, Chemical; Vagus Nerve | 2006 |
The enhancing effects of peptidase inhibitors on the antinociceptive action of [Met5]enkephalin-Arg6-Phe7 in rats.
Topics: Analgesics; Animals; Captopril; Dose-Response Relationship, Drug; Drug Synergism; Enkephalin, Methionine; Glycopeptides; Injections, Intraventricular; Injections, Subcutaneous; Male; Naloxone; Narcotic Antagonists; Pain; Pain Measurement; Peptides; Protease Inhibitors; Rats; Rats, Wistar | 2007 |
The impact of postnatal environment on opioid peptides in young and adult male Wistar rats.
Topics: Age Factors; Animals; Animals, Newborn; Body Weight; Dynorphins; Endorphins; Enkephalin, Methionine; Environment; Female; Male; Maternal Behavior; Maternal Deprivation; Opioid Peptides; Pituitary Gland; Pregnancy; Rats; Rats, Wistar; Social Isolation; Stress, Psychological | 2008 |
The OGF-OGFr axis utilizes the p21 pathway to restrict progression of human pancreatic cancer.
Topics: Blotting, Western; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase Inhibitor p21; Disease Progression; Enkephalin, Methionine; Flow Cytometry; Humans; Pancreatic Neoplasms; Receptors, Opioid; Retinoblastoma Protein; RNA, Small Interfering; Signal Transduction; Transfection | 2008 |
Mu-opioid receptor activation in live cells.
Topics: Animals; Cell Membrane; Endocytosis; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Methionine; Green Fluorescent Proteins; Humans; Membrane Lipids; Methadone; Models, Biological; Morphine; PC12 Cells; Rats; Receptors, Opioid, mu | 2008 |
Phylogenetic diversity and functional efficacy of the C-terminally expressed heptapeptide unit in the opioid precursor polypeptide proenkephalin A.
Topics: Animals; Enkephalin, Methionine; Enkephalins; Guinea Pigs; HEK293 Cells; Humans; Oligopeptides; Peptide Fragments; Phylogeny; Polymorphism, Genetic; Radioligand Assay; Rats; Rats, Wistar; Receptors, Opioid; Sequence Analysis; Sulfur Radioisotopes; Vertebrates | 2011 |
The action of a synthetic derivative of Met5-enkephalin-Arg6-Phe7 on behavioral and endocrine responses.
Topics: Animals; Behavior, Animal; Enkephalin, Methionine; Enkephalins; Hypothalamo-Hypophyseal System; Male; Mice; Mice, Inbred Strains; Naloxone; Naltrexone; Oligopeptides; Pituitary-Adrenal System | 2011 |
Differences in basal and ethanol-induced levels of opioid peptides in Wistar rats from five different suppliers.
Topics: Alcohol Drinking; Animals; Animals, Outbred Strains; Brain; Choice Behavior; Dynorphins; Endorphins; Enkephalin, Methionine; Ethanol; Male; Opioid Peptides; Organ Specificity; Pituitary Gland; Rats; Rats, Wistar; Species Specificity; Statistics, Nonparametric | 2012 |
Opiorphin highly improves the specific binding and affinity of MERF and MEGY to rat brain opioid receptors.
Topics: Animals; Binding, Competitive; Brain; Cell Membrane; Enkephalin, Methionine; Male; Oligopeptides; Protease Inhibitors; Protein Binding; Rats; Rats, Inbred Strains; Rats, Wistar; Receptors, Opioid; Salivary Proteins and Peptides | 2012 |
Cannabinoid-1 receptors in the mouse ventral pallidum are targeted to axonal profiles expressing functionally opposed opioid peptides and contacting N-acylphosphatidylethanolamine-hydrolyzing phospholipase D terminals.
Topics: Animals; Dynorphins; Enkephalin, Methionine; Globus Pallidus; Male; Mice; Mice, Inbred C57BL; Microscopy, Immunoelectron; Neurons; Peptide Fragments; Phospholipase D; Presynaptic Terminals; Receptor, Cannabinoid, CB1 | 2012 |
Effects of rearing conditions on behaviour and endogenous opioids in rats with alcohol access during adolescence.
Topics: Age Factors; Alcohol Drinking; Amygdala; Animals; Animals, Newborn; Behavior, Animal; beta-Endorphin; Dynorphins; Endorphins; Enkephalin, Methionine; Female; Hippocampus; Male; Maternal Deprivation; Periaqueductal Gray; Pituitary Gland; Rats; Rats, Wistar; Risk-Taking; Stress, Physiological | 2013 |
Single housing during early adolescence causes time-, area- and peptide-specific alterations in endogenous opioids of rat brain.
Topics: Aging; Animals; Brain; Dynorphins; Endorphins; Enkephalin, Methionine; Housing, Animal; Male; Nociceptin; Opioid Peptides; Rats, Sprague-Dawley; Social Environment | 2015 |
Effects of synthetic analogues of human opiorphin on rat brain opioid receptors.
Topics: Animals; Binding, Competitive; Brain; Enkephalin, Methionine; Humans; Oligopeptides; Rats, Wistar; Receptors, Opioid; Salivary Proteins and Peptides | 2014 |
Systematic analysis of factors influencing observations of biased agonism at the mu-opioid receptor.
Topics: Analgesics, Opioid; Animals; CHO Cells; Cricetulus; Drug Discovery; Endorphins; Enkephalin, Methionine; Ligands; Membrane Potentials; Opioid Peptides; Protein Precursors; Receptors, Opioid, mu; Signal Transduction | 2016 |
Angiotensin-converting enzyme gates brain circuit-specific plasticity via an endogenous opioid.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Behavior, Animal; Captopril; Enkephalin, Methionine; Female; Fentanyl; Male; Mice; Miniature Postsynaptic Potentials; Neuronal Plasticity; Nucleus Accumbens; Opioid Peptides; Patch-Clamp Techniques; Peptidyl-Dipeptidase A | 2022 |