Page last updated: 2024-09-04

enkephalin-leu, des-tyr(1)- and naloxone

enkephalin-leu, des-tyr(1)- has been researched along with naloxone in 3 studies

Compound Research Comparison

Studies
(enkephalin-leu, des-tyr(1)-)
Trials
(enkephalin-leu, des-tyr(1)-)
Recent Studies (post-2010)
(enkephalin-leu, des-tyr(1)-)
Studies
(naloxone)
Trials
(naloxone)
Recent Studies (post-2010) (naloxone)
140120,1341,2573,321

Protein Interaction Comparison

ProteinTaxonomyenkephalin-leu, des-tyr(1)- (IC50)naloxone (IC50)
Cytochrome P450 2D6Homo sapiens (human)2
Delta-type opioid receptorMus musculus (house mouse)0.043
Delta-type opioid receptorRattus norvegicus (Norway rat)0.0219
Mu-type opioid receptorRattus norvegicus (Norway rat)0.0019
Kappa-type opioid receptorRattus norvegicus (Norway rat)0.0019
Mu-type opioid receptorHomo sapiens (human)0.0397
Delta-type opioid receptorHomo sapiens (human)0.1896
Kappa-type opioid receptorCavia porcellus (domestic guinea pig)0.05
Kappa-type opioid receptorHomo sapiens (human)0.0795
Mu-type opioid receptorMus musculus (house mouse)0.0154
Mu-type opioid receptorCavia porcellus (domestic guinea pig)0.0089
Beta-2 adrenergic receptorCavia porcellus (domestic guinea pig)0.0055

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19901 (33.33)18.7374
1990's2 (66.67)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Janak, PH; Martinez, JL1
Henry, JL; Rochford, J1
Michaelson, DM; Wien-Naor, D1

Other Studies

3 other study(ies) available for enkephalin-leu, des-tyr(1)- and naloxone

ArticleYear
Only tyrosine-containing metabolites of [Leu]enkephalin impair active avoidance conditioning in mice.
    Pharmacology, biochemistry, and behavior, 1990, Volume: 37, Issue:4

    Topics: Amino Acid Sequence; Animals; Avoidance Learning; Enkephalin, Leucine; Male; Mice; Molecular Sequence Data; Motor Activity; Naloxone; Oligopeptides; Tyrosine

1990
Intrathecal administration of delta receptor agonists in the urethane anesthetized rat provokes an increase in arterial pressure via a non-opioid mechanism.
    Brain research, 1990, Apr-02, Volume: 512, Issue:2

    Topics: Anesthesia; Animals; Blood Pressure; Cardiovascular Physiological Phenomena; Cardiovascular System; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalins; Heart Rate; Injections, Spinal; Male; Naloxone; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Spinal Cord; Urethane

1990
Enkephalin uptake into cholinergic synaptic vesicles and nerve terminals.
    Annals of the New York Academy of Sciences, 1987, Volume: 493

    Topics: Acetylcholine; Animals; Electric Organ; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Kinetics; Morphine; Naloxone; Nerve Endings; Synaptic Vesicles; Synaptosomes; Torpedo

1987