Page last updated: 2024-09-02

enkephalin, ser(2), leu(5), thr(6)- and norbinaltorphimine

enkephalin, ser(2), leu(5), thr(6)- has been researched along with norbinaltorphimine in 5 studies

Compound Research Comparison

Studies
(enkephalin, ser(2), leu(5), thr(6)-)
Trials
(enkephalin, ser(2), leu(5), thr(6)-)
Recent Studies (post-2010)
(enkephalin, ser(2), leu(5), thr(6)-)
Studies
(norbinaltorphimine)
Trials
(norbinaltorphimine)
Recent Studies (post-2010) (norbinaltorphimine)
224059180205

Protein Interaction Comparison

ProteinTaxonomyenkephalin, ser(2), leu(5), thr(6)- (IC50)norbinaltorphimine (IC50)
Delta-type opioid receptorMus musculus (house mouse)0.0104
Kappa-type opioid receptorMus musculus (house mouse)0.0029
Mu-type opioid receptorHomo sapiens (human)0.212
Delta-type opioid receptorHomo sapiens (human)0.024
Kappa-type opioid receptorHomo sapiens (human)0.0036

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19901 (20.00)18.7374
1990's3 (60.00)18.2507
2000's1 (20.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Adapa, ID; Auh, JS; Berzetei-Gurske, IP; Brandt, SR; Craymer, K; Farrington, L; Haggart, D; Kennedy, JM; O'Brien, A; Polgar, WE; Rodriguez, L; Schwartz, RW; Toll, L; White, A1
Billington, CJ; Grace, M; Levine, AS; Portoghese, PS1
Ho, BY; Naeseth, JS; Portoghese, PS; Takemori, AE1
Childers, SR; Sim, LJ1
Brown, DR; Poonyachoti, S; Portoghese, PS1

Other Studies

5 other study(ies) available for enkephalin, ser(2), leu(5), thr(6)- and norbinaltorphimine

ArticleYear
Standard binding and functional assays related to medications development division testing for potential cocaine and opiate narcotic treatment medications.
    NIDA research monograph, 1998, Volume: 178

    Topics: Animals; Aorta, Thoracic; Cocaine; Cyclic AMP; Electric Stimulation; Guinea Pigs; Humans; Ileum; In Vitro Techniques; Male; Mice; Muscle, Smooth; Opioid-Related Disorders; Rats; Receptors, Dopamine; Receptors, Opioid; Receptors, Serotonin; Substance-Related Disorders

1998
Nor-binaltorphimine decreases deprivation and opioid-induced feeding.
    Brain research, 1990, Nov-26, Volume: 534, Issue:1-2

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Feeding Behavior; Food Deprivation; Male; Naltrexone; Oligopeptides; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Opioid; Reference Values

1990
Nor-binaltorphimine, a highly selective kappa-opioid antagonist in analgesic and receptor binding assays.
    The Journal of pharmacology and experimental therapeutics, 1988, Volume: 246, Issue:1

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesia; Animals; Cyclazocine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Ethylketocyclazocine; Guinea Pigs; Male; Mice; Morphine; Naltrexone; Oligopeptides; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, kappa

1988
Anatomical distribution of mu, delta, and kappa opioid- and nociceptin/orphanin FQ-stimulated [35S]guanylyl-5'-O-(gamma-thio)-triphosphate binding in guinea pig brain.
    The Journal of comparative neurology, 1997, Oct-06, Volume: 386, Issue:4

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Analgesics, Non-Narcotic; Animals; Autoradiography; Brain Chemistry; Cerebellum; Diencephalon; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Guanosine 5'-O-(3-Thiotriphosphate); Guinea Pigs; Male; Medulla Oblongata; Mesencephalon; Naloxone; Naltrexone; Narcotic Antagonists; Nociceptin; Opioid Peptides; Pons; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Sulfur Radioisotopes; Telencephalon

1997
Characterization of opioid receptors modulating neurogenic contractions of circular muscle from porcine ileum and evidence that delta- and kappa-opioid receptors are coexpressed in myenteric neurons.
    The Journal of pharmacology and experimental therapeutics, 2001, Volume: 297, Issue:1

    Topics: Amino Acid Sequence; Animals; Electric Stimulation; Enkephalin, Leucine; Goats; Ileum; In Vitro Techniques; Molecular Sequence Data; Muscle Contraction; Muscle, Smooth; Myenteric Plexus; Naltrexone; Rabbits; Receptors, Opioid, delta; Receptors, Opioid, kappa; Swine

2001