enkephalin, ser(2), leu(5), thr(6)- has been researched along with morphine in 40 studies
| Studies (enkephalin, ser(2), leu(5), thr(6)-) | Trials (enkephalin, ser(2), leu(5), thr(6)-) | Recent Studies (post-2010) (enkephalin, ser(2), leu(5), thr(6)-) | Studies (morphine) | Trials (morphine) | Recent Studies (post-2010) (morphine) |
|---|---|---|---|---|---|
| 224 | 0 | 5 | 44,270 | 5,200 | 8,695 |
| Protein | Taxonomy | enkephalin, ser(2), leu(5), thr(6)- (IC50) | morphine (IC50) |
|---|---|---|---|
| Delta-type opioid receptor | Mus musculus (house mouse) | 0.2939 | |
| Delta-type opioid receptor | Rattus norvegicus (Norway rat) | 0.2278 | |
| Kappa-type opioid receptor | Mus musculus (house mouse) | 0.0828 | |
| Mu-type opioid receptor | Rattus norvegicus (Norway rat) | 0.0385 | |
| Kappa-type opioid receptor | Rattus norvegicus (Norway rat) | 0.0545 | |
| Mu-type opioid receptor | Homo sapiens (human) | 0.122 | |
| Delta-type opioid receptor | Homo sapiens (human) | 0.1199 | |
| Kappa-type opioid receptor | Cavia porcellus (domestic guinea pig) | 0.9308 | |
| Kappa-type opioid receptor | Homo sapiens (human) | 0.655 | |
| Mu-type opioid receptor | Mus musculus (house mouse) | 0.3305 | |
| Mu-type opioid receptor | Cavia porcellus (domestic guinea pig) | 0.202 | |
| Beta-2 adrenergic receptor | Cavia porcellus (domestic guinea pig) | 0.25 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (32.50) | 18.7374 |
| 1990's | 24 (60.00) | 18.2507 |
| 2000's | 2 (5.00) | 29.6817 |
| 2010's | 1 (2.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Portoghese, PS; Sultana, M; Takemori, AE | 1 |
| Daugé, V; Delay-Goyet, P; Gacel, G; Roques, BP; Zajac, JM | 1 |
| Bell, GI; Chen, Y; Kong, H; Raynor, K; Reisine, T; Yasuda, K; Yu, L | 1 |
| Moe, ST; Portoghese, PS; Takemori, AE | 1 |
| Adapa, ID; Auh, JS; Berzetei-Gurske, IP; Brandt, SR; Craymer, K; Farrington, L; Haggart, D; Kennedy, JM; O'Brien, A; Polgar, WE; Rodriguez, L; Schwartz, RW; Toll, L; White, A | 1 |
| Grossman, A; Hucks, D; Joel, SP; McLoughlin, L; Patel, N; Rees, LH; Slevin, ML; Thompson, PI | 1 |
| McDonald, JS; Rattan, AK; Tejwani, GA | 1 |
| Il'ina, AD; Iukhananov, RIu; Klodt, PM; Varfolomeev, SD; Zaĭtsev, SV | 1 |
| Bhargava, HN; Gulati, A | 1 |
| Bhargava, HN; Gulati, A; Rahmani, NH | 1 |
| Bodnar, R; Pasternak, GW; Paul, D | 1 |
| Bodnar, RJ; Kepler, KL; Kest, B; Pasternak, GW; Paul, D; Standifer, KM | 1 |
| Boon, F; Cain, DP; Corcoran, ME | 1 |
| Andreou, A; Angelopoulos, EK; Koutsoukos, E; Loukas, S; Maillis, A; Stefanis, C; Zioudrou, C | 1 |
| deGroat, WC; Hisamitsu, T; Nagel, J; Roppolo, JR; Thor, KB; Tuttle, P | 1 |
| Basbaum, AI; Levine, JD; Perry, F; Taiwo, YO | 1 |
| Bodnar, RJ; Gistrak, MA; Pasternak, GW; Paul, D | 1 |
| Bockaert, J; Eybalin, M; Pujol, R | 1 |
| Bodnar, RJ; Lee, SJ; Pasternak, GW; Williams, CL | 1 |
| Ho, BY; Naeseth, JS; Portoghese, PS; Takemori, AE | 1 |
| Jensen, TS; Yaksh, TL | 1 |
| Snead, OC | 1 |
| Heyman, JS; Mosberg, HI; Omnaas, JR; Porreca, F; Vaught, JL | 1 |
| Flórez, J; Pazos, A | 2 |
| de Groat, WC; Hisamitsu, T | 1 |
| Cupo, A; Garreau, I; Pejoan, C; Piot, JM; Zhao, Q | 1 |
| Il'Ina, AD; Klodt, PM; Maisky, AI; Zaitsev, SV | 1 |
| Lanthorn, TH; Watson, GB | 1 |
| Miyamoto, Y; Portoghese, PS; Takemori, AE | 1 |
| Coupar, IM | 1 |
| Hruby, VJ; Kovelowski, CJ; Nichols, ML; Ossipov, MH; Porreca, F | 1 |
| Bakogeorgou, E; Castanas, E; Hatzoglou, A | 1 |
| Ingram, S; McCleskey, EW; Wilding, TJ; Williams, JT | 1 |
| Blake, AD; Bot, G; Li, S; Reisine, T | 1 |
| Kramer, HK; Simon, EJ | 1 |
| Fujimoto, JM; Holmes, BB; Rady, JJ | 1 |
| Inoue, M; Ueda, H | 1 |
| Campbell, WB; Fujimoto, JM; Rady, JJ | 1 |
| Agalou, A; Georganta, EM; Georgoussi, Z | 1 |
40 other study(ies) available for enkephalin, ser(2), leu(5), thr(6)- and morphine
| Article | Year |
|---|---|
Naltrindole 5'-isothiocyanate: a nonequilibrium, highly selective delta opioid receptor antagonist.
Topics: Affinity Labels; Animals; Chemical Phenomena; Chemistry; Isothiocyanates; Male; Mice; Morphinans; Naltrexone; Narcotic Antagonists; Receptors, Opioid, delta; Thiocyanates | 1990 |
Investigation of the structural parameters involved in the mu and delta opioid receptor discrimination of linear enkephalin-related peptides.
Topics: Analgesics; Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Guinea Pigs; Mice; Muscle Contraction; Oligopeptides; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Structure-Activity Relationship | 1988 |
Pharmacological characterization of the cloned kappa-, delta-, and mu-opioid receptors.
Topics: Analgesics; Animals; Binding Sites; Cell Line; CHO Cells; Cloning, Molecular; Cricetinae; Ligands; PC12 Cells; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Software | 1994 |
A selective delta 1 opioid receptor agonist derived from oxymorphone. Evidence for separate recognition sites for delta 1 opioid receptor agonists and antagonists.
Topics: Animals; Brain; Dose-Response Relationship, Drug; Guinea Pigs; Male; Mice; Muscle, Smooth; Oxymorphone; Receptors, Opioid, delta; Spiro Compounds; Stereoisomerism; Structure-Activity Relationship; Vas Deferens | 1993 |
Standard binding and functional assays related to medications development division testing for potential cocaine and opiate narcotic treatment medications.
Topics: Animals; Aorta, Thoracic; Cocaine; Cyclic AMP; Electric Stimulation; Guinea Pigs; Humans; Ileum; In Vitro Techniques; Male; Mice; Muscle, Smooth; Opioid-Related Disorders; Rats; Receptors, Dopamine; Receptors, Opioid; Receptors, Serotonin; Substance-Related Disorders | 1998 |
Explanation at the opioid receptor level for differing toxicity of morphine and morphine 6-glucuronide.
Topics: Animals; Brain; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalins; Kinetics; Morphine; Morphine Derivatives; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Subcellular Fractions | 1992 |
Role of spinal opioid receptors in the antinociceptive interactions between intrathecal morphine and bupivacaine.
Topics: Analgesics; Animals; Bupivacaine; Dose-Response Relationship, Drug; Drug Synergism; Enkephalin, Leucine; Injections, Spinal; Male; Morphine; Naloxone; Pain; Rats; Rats, Inbred Strains; Receptors, Opioid; Spinal Cord | 1992 |
[Heterogeneity of mu- and delta-opioid active sites in the mouse cerebral cortex. Selective increase in the affinity of a superhigh affinity delta-site during long-term administration of morphine].
Topics: Animals; Cerebral Cortex; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Male; Mice; Mice, Inbred C57BL; Morphine; Receptors, Opioid, delta; Receptors, Opioid, mu; Substrate Specificity | 1992 |
The effect of morphine tolerance-dependence and abstinence on mu, delta, and kappa opiate receptors of discrete brain regions and spinal cord of the rat.
Topics: Animals; Brain Chemistry; Drug Tolerance; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Ethylketocyclazocine; In Vitro Techniques; Male; Morphine; Morphine Dependence; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Spinal Cord; Substance Withdrawal Syndrome | 1990 |
Differences in the binding of [3H][D-Ser2,Thr6]leucine-enkephalin and [3H][D-Pen2,D-Pen5]enkephalin to brain membranes of morphine tolerant-dependent rats.
Topics: Analgesics; Animals; Brain; Cell Membrane; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalins; Ligands; Male; Morphine; Radioimmunoassay; Rats; Rats, Inbred Strains; Receptors, Opioid; Spinal Cord; Substance-Related Disorders | 1991 |
Synergistic analgesic interactions between the periaqueductal gray and the locus coeruleus.
Topics: Analgesics; Animals; Enkephalin, Leucine; Ethylketocyclazocine; Locus Coeruleus; Male; Microinjections; Morphine; Narcotic Antagonists; Periaqueductal Gray; Raphe Nuclei; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Reticular Formation; Stereotaxic Techniques | 1991 |
Gender effects and central opioid analgesia.
Topics: Analgesics, Opioid; Animals; Brain; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Female; Injections, Intraventricular; Male; Morphine; Narcotics; Rats; Rats, Inbred Strains; Reaction Time; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Seminal Vesicles; Sensory Thresholds; Sex Characteristics; Uterus | 1991 |
Involvement of multiple opiate receptors in opioid kindling.
Topics: Animals; beta-Endorphin; Convulsants; Endorphins; Enkephalin, Leucine; Kindling, Neurologic; Male; Morphine; Oligopeptides; Rats; Receptors, Opioid | 1990 |
Effects of iontophoretically applied alpha-casein exorphin on CA1 hippocampal field potentials in vivo.
Topics: Amino Acid Sequence; Animals; Caseins; Electric Stimulation; Enkephalin, Leucine; Evoked Potentials; Hippocampus; Iontophoresis; Molecular Sequence Data; Morphine; Naloxone; Peptide Fragments; Rats; Rats, Inbred Strains | 1990 |
Selective inhibitory effects of ethylketocyclazocine on reflex pathways to the external urethral sphincter of the cat.
Topics: Animals; Cats; Cyclazocine; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Ethylketocyclazocine; Female; Morphine; Naloxone; Oligopeptides; Receptors, Opioid; Receptors, Opioid, kappa; Reflex; Urethra; Urinary Bladder; Urinary Incontinence | 1989 |
Paradoxical analgesia produced by low doses of the opiate-antagonist naloxone is mediated by interaction at a site with characteristics of the delta opioid receptor.
Topics: Analgesia; Animals; Dose-Response Relationship, Drug; Endorphins; Enkephalin, Leucine; Male; Morphine; Naloxone; Oligopeptides; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta | 1989 |
Different mu receptor subtypes mediate spinal and supraspinal analgesia in mice.
Topics: Analgesia; Anesthesia, Spinal; Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalins; Injections, Intraventricular; Injections, Spinal; Male; Mice; Morphine; Naloxone; Oligopeptides; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu | 1989 |
Opioid receptors inhibit the adenylate cyclase in guinea pig cochleas.
Topics: Adenylyl Cyclases; Animals; Cochlea; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Guinea Pigs; In Vitro Techniques; Morphine; Naloxone; Oligopeptides; Receptors, Opioid | 1987 |
Role of mu 1-opiate receptors in supraspinal opiate analgesia: a microinjection study.
Topics: Analgesia; Animals; Brain; Cerebral Ventricles; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalins; Injections, Intravenous; Injections, Intraventricular; Male; Microinjections; Morphine; Oligopeptides; Organ Specificity; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, mu; Spinal Cord | 1988 |
Nor-binaltorphimine, a highly selective kappa-opioid antagonist in analgesic and receptor binding assays.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesia; Animals; Cyclazocine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Ethylketocyclazocine; Guinea Pigs; Male; Mice; Morphine; Naltrexone; Oligopeptides; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, kappa | 1988 |
Comparison of the antinociceptive action of mu and delta opioid receptor ligands in the periaqueductal gray matter, medial and paramedial ventral medulla in the rat as studied by the microinjection technique.
Topics: Analgesics, Opioid; Animals; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Fentanyl; Male; Medulla Oblongata; Morphine; Naloxone; Oligopeptides; Periaqueductal Gray; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Sufentanil | 1986 |
Opiate-induced seizures: a study of mu and delta specific mechanisms.
Topics: Animals; Electroencephalography; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Morphine; Narcotics; Oligopeptides; Rats; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Seizures | 1986 |
Role of mu and delta receptors in the supraspinal and spinal analgesic effects of [D-Pen2, D-Pen5]enkephalin in the mouse.
Topics: Analgesia; Anesthesia, Spinal; Animals; Drug Synergism; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Male; Mice; Morphine; Oligopeptides; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu | 1987 |
Interaction of naloxone with mu- and delta-opioid agonists on the respiration of rats.
Topics: Animals; D-Ala(2),MePhe(4),Met(0)-ol-enkephalin; Depression, Chemical; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Enkephalins; Female; Injections, Intraventricular; Male; Morphine; Naloxone; Narcotics; Oligopeptides; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Respiration; Time Factors | 1983 |
A comparative study in rats of the respiratory depression and analgesia induced by mu- and delta-opioid agonists.
Topics: Analgesia; Animals; D-Ala(2),MePhe(4),Met(0)-ol-enkephalin; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Female; Male; Morphine; Oligopeptides; Rats; Rats, Inbred Strains; Respiration | 1984 |
The inhibitory effect of opioid peptides and morphine applied intrathecally and intracerebroventricularly on the micturition reflex in the cat.
Topics: Animals; Cats; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Enkephalins; Female; Morphine; Naloxone; Oligopeptides; Reflex; Thiorphan; Tiopronin; Urination | 1984 |
VV-hemorphin-7 and LVV-hemorphin-7 released during in vitro peptic hemoglobin hydrolysis are morphinomimetic peptides.
Topics: Animals; Binding, Competitive; Cattle; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Guinea Pigs; Hemoglobins; Hydrolysis; Ileum; Male; Morphine; Naloxone; Pepsin A; Peptide Fragments; Rats; Rats, Wistar; Receptors, Opioid; Sensitivity and Specificity | 1995 |
Opiate withdrawal intensity correlates with the presence of DSLET high-affinity binding.
Topics: Amino Acid Sequence; Analgesics; Animals; Drug Implants; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Molecular Sequence Data; Morphine; Morphine Dependence; Naloxone; Narcotics; Receptors, Opioid, delta; Receptors, Opioid, mu; Substance Withdrawal Syndrome | 1994 |
Electrophysiological actions of delta opioids in CA1 of the rat hippocampal slice are mediated by one delta receptor subtype.
Topics: Analgesics; Animals; Electric Stimulation; Electrophysiology; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalins; Evoked Potentials; Hippocampus; In Vitro Techniques; Indoles; Ligands; Male; Morphinans; Morphine; Naltrexone; Narcotic Antagonists; Pyramidal Tracts; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, mu | 1993 |
Involvement of delta 2 opioid receptors in acute dependence on morphine in mice.
Topics: Animals; Drug Interactions; Enkephalin, Leucine; Isothiocyanates; Male; Mice; Morphine; Naltrexone; Receptors, Opioid, delta; Substance-Related Disorders; Thiocyanates | 1993 |
The peristaltic reflex in the rat ileum: evidence for functional mu- and delta-opiate receptors.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Antidiarrheals; Diphenoxylate; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Ileum; Linear Models; Loperamide; Morphine; Peristalsis; Pyrrolidines; Rats; Receptors, Opioid, delta; Receptors, Opioid, mu | 1995 |
Characterization of supraspinal antinociceptive actions of opioid delta agonists in the rat.
Topics: Animals; Cerebral Ventricles; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Hot Temperature; Injections, Intraventricular; Male; Medulla Oblongata; Morphine; Nociceptors; Oligopeptides; Pain Measurement; Periaqueductal Gray; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Reticular Formation | 1995 |
The antiproliferative effect of opioid receptor agonists on the T47D human breast cancer cell line, is partially mediated through opioid receptors.
Topics: Adenocarcinoma; Amino Acid Sequence; Binding Sites; Breast Neoplasms; Cell Division; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Ethylketocyclazocine; Etorphine; Humans; Molecular Sequence Data; Morphine; Narcotic Antagonists; Opioid Peptides; Receptors, Opioid; Tumor Cells, Cultured | 1996 |
Efficacy and kinetics of opioid action on acutely dissociated neurons.
Topics: Animals; Brimonidine Tartrate; Calcium Channels; Clonidine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; Etorphine; Locus Coeruleus; Morphine; Narcotics; Potassium Channels; Quinoxalines | 1997 |
Opioid regulation of the mouse delta-opioid receptor expressed in human embryonic kidney 293 cells.
Topics: Adenylyl Cyclases; Animals; Antibodies, Monoclonal; Cell Line; Colforsin; Cyclic AMP; Down-Regulation; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Etorphine; GTP-Binding Proteins; Humans; Methadone; Mice; Morphine; Point Mutation; Radioligand Assay; Receptors, Opioid, delta; Signal Transduction; Structure-Activity Relationship | 1997 |
Role of protein kinase C (PKC) in agonist-induced mu-opioid receptor down-regulation: I. PKC translocation to the membrane of SH-SY5Y neuroblastoma cells is induced by mu-opioid agonists.
Topics: Analgesics; Analgesics, Opioid; Binding, Competitive; Biological Transport; Carcinogens; Diprenorphine; Down-Regulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Humans; Kinetics; Membrane Proteins; Morphine; Naloxone; Narcotic Antagonists; Neuroblastoma; Phorbol 12,13-Dibutyrate; Protein Kinase C; Receptors, Opioid, mu; Second Messenger Systems; Time Factors; Tritium; Tumor Cells, Cultured | 1999 |
Antianalgesic action of dynorphin A mediated by spinal cholecystokinin.
Topics: Analgesia; Analgesics; Animals; Antibodies; Cholecystokinin; Dynorphins; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalins; Indoles; Injections, Spinal; Male; Meglumine; Mice; Morphine; Proglumide; Receptors, Cholecystokinin; Receptors, Opioid, delta; Spinal Cord | 1999 |
Protein kinase C-mediated acute tolerance to peripheral mu-opioid analgesia in the bradykinin-nociception test in mice.
Topics: Analgesics, Opioid; Animals; Benzeneacetamides; Blotting, Western; Bradykinin; Dose-Response Relationship, Drug; Down-Regulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enzyme Inhibitors; Male; Mice; Morphine; Nociceptors; Oligonucleotides, Antisense; Pain Measurement; Peripheral Nervous System; Protein Kinase C; Pyrrolidines; Receptors, Opioid, kappa; Receptors, Opioid, mu | 2000 |
Antianalgesic action of nociceptin originating in the brain is mediated by spinal prostaglandin E(2) in mice.
Topics: Analgesics, Opioid; Animals; Brain; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Indomethacin; Injections, Intraventricular; Injections, Spinal; Male; Mice; Morphine; Nociceptin; Opioid Peptides; Pain Measurement; Receptors, Prostaglandin; Spinal Cord; Substance P | 2001 |
Multi-component signaling complexes of the delta-opioid receptor with STAT5B and G proteins.
Topics: Amino Acid Sequence; Analgesics, Opioid; Cell Line, Transformed; Conserved Sequence; Enkephalin, Leucine; Enzyme Activation; Enzyme Inhibitors; GTP-Binding Proteins; Humans; Immunoprecipitation; Morphine; Mutation; Pertussis Toxin; Phosphorylation; Protein Binding; Protein Structure, Tertiary; Protein Subunits; Pyrazoles; Pyrimidines; Receptors, Opioid, delta; Signal Transduction; STAT5 Transcription Factor; Transfection; Tyrosine | 2010 |