enkephalin, ser(2), leu(5), thr(6)- and enkephalin, leucine-2-alanine

enkephalin, ser(2), leu(5), thr(6)- has been researched along with enkephalin, leucine-2-alanine in 48 studies

Compound Research Comparison

Studies (enkephalin, ser(2), leu(5), thr(6)-)	Trials (enkephalin, ser(2), leu(5), thr(6)-)	Recent Studies (post-2010) (enkephalin, ser(2), leu(5), thr(6)-)	Studies (enkephalin, leucine-2-alanine)	Trials (enkephalin, leucine-2-alanine)	Recent Studies (post-2010) (enkephalin, leucine-2-alanine)
224	0	5	1,581	23	74

Protein Interaction Comparison

Protein	Taxonomy	enkephalin, leucine-2-alanine (IC50)
Delta-type opioid receptor	Mus musculus (house mouse)	0.0915
Delta-type opioid receptor	Rattus norvegicus (Norway rat)	0.0017
Kappa-type opioid receptor	Mus musculus (house mouse)	0.009
Mu-type opioid receptor	Rattus norvegicus (Norway rat)	0.0419
Kappa-type opioid receptor	Cavia porcellus (domestic guinea pig)	1.4691
Mu-type opioid receptor	Mus musculus (house mouse)	0.009

Research

Studies (48)

Timeframe	Studies, this research(%)	All Research%
pre-1990	27 (56.25)	18.7374
1990's	21 (43.75)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Portoghese, PS; Sultana, M; Takemori, AE	1
Daugé, V; Delay-Goyet, P; Gacel, G; Roques, BP; Zajac, JM	1
Bell, GI; Chen, Y; Kong, H; Raynor, K; Reisine, T; Yasuda, K; Yu, L	1
Adapa, ID; Auh, JS; Berzetei-Gurske, IP; Brandt, SR; Craymer, K; Farrington, L; Haggart, D; Kennedy, JM; O'Brien, A; Polgar, WE; Rodriguez, L; Schwartz, RW; Toll, L; White, A	1
Childers, SR; Fleming, L; Konkoy, C; Marckel, D; Pacheco, M; Sexton, T; Ward, S	1
Olianas, MC; Onali, P	1
Portoghese, PS; Sofuoglu, M; Takemori, AE	1
Bowen, WD; Jiang, Q; Mosberg, HI; Porreca, F; Portoghese, PS; Sultana, M; Takemori, AE	1
Barfolomeev, SD; Kurochkin, IN; Melikhova, EV; Sukhovlin, TK	1
La Regina, A; Petrillo, P; Sbacchi, M; Tavani, A	1
deGroat, WC; Hisamitsu, T; Nagel, J; Roppolo, JR; Thor, KB; Tuttle, P	1
de Castiglione, R; Guglietta, A; Lazarus, LH; Wilson, WE	1
Bowen, WD; Herkenham, M; Jacobson, AE; Pert, CB; Rice, KC; Rothman, RB	1
Hoffman, PL; Khatami, S; Salafsky, B; Shibuya, T	1
Smith, CB	1
Bhargava, HN; Rapaka, RS; Renugopalakrishnan, V	1
Barnard, EA; Demoliou-Mason, CD; Wong, YH	1
Ho, BY; Naeseth, JS; Portoghese, PS; Takemori, AE	1
Jensen, TS; Yaksh, TL	1
Clark, JA; Houghten, R; Pasternak, GW	1
Burke, TR; Danks, JA; Herkenham, M; Jacobson, AE; Rice, KC; Rothman, RB	1
Boudouresque, F; Bourhim, N; Cantau, P; Castanas, E; Giraud, P; Oliver, C	2
Coletti-Previero, MA; Descomps, B; Martin, JL; Roques, BP	1
Portoghese, PS; Takemori, AE	1
Snead, OC	1
Brown, SR; Cox, BM; Puttfarcken, P; Werling, LL	1
Clark, JA; Hruby, VJ; Itzhak, Y; Pasternak, GW; Yamamura, HI	1
Heyman, JS; Mosberg, HI; Omnaas, JR; Porreca, F; Vaught, JL	1
Geladopoulos, T; Sakellaridis, N; Vernadakis, A	1
Belknap, JK; Laursen, SE	1
Pert, CB; Rothman, RB; Schumacher, UK	1
Flórez, J; Pazos, A	2
Burks, TF; Galligan, JJ; Gee, K; Hruby, VJ; Hurst, R; Mosberg, HI; Yamamura, HI	1
de Groat, WC; Hisamitsu, T	1
Cucumel, K; Cupo, A	1
Coupar, IM; Hancock, DL	1
Barannik, VL; Lishmanov, IuB; Maslov, LN; Ugdyzhekova, DS	1
Erikson, LJ; Evans, C; Law, PY; Loh, HH; McGinn, TM; Wick, MJ	1
Coupar, IM	1
Hruby, VJ; Kovelowski, CJ; Nichols, ML; Ossipov, MH; Porreca, F	1
Bakogeorgou, E; Castanas, E; Hatzoglou, A	1
Christensen, CB; Christrup, LL; Kristensen, K; Nielsen, LC	1
Blake, AD; Bot, G; Li, S; Reisine, T	2
Chen, J; Chi, ZQ; Li, GE; Pei, G; Wang, CH; Zhou, DH	1
Bebiakova, NA; Mikhaĭlova, SD; Semushkina, TM; Sokolov, AV; Storozhakov, GI	1

Other Studies

48 other study(ies) available for enkephalin, ser(2), leu(5), thr(6)- and enkephalin, leucine-2-alanine

Article	Year
Naltrindole 5'-isothiocyanate: a nonequilibrium, highly selective delta opioid receptor antagonist. Journal of medicinal chemistry, 1990, Volume: 33, Issue:6 Topics: Affinity Labels; Animals; Chemical Phenomena; Chemistry; Isothiocyanates; Male; Mice; Morphinans; Naltrexone; Narcotic Antagonists; Receptors, Opioid, delta; Thiocyanates	1990
Investigation of the structural parameters involved in the mu and delta opioid receptor discrimination of linear enkephalin-related peptides. Journal of medicinal chemistry, 1988, Volume: 31, Issue:2 Topics: Analgesics; Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Guinea Pigs; Mice; Muscle Contraction; Oligopeptides; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Structure-Activity Relationship	1988
Pharmacological characterization of the cloned kappa-, delta-, and mu-opioid receptors. Molecular pharmacology, 1994, Volume: 45, Issue:2 Topics: Analgesics; Animals; Binding Sites; Cell Line; CHO Cells; Cloning, Molecular; Cricetinae; Ligands; PC12 Cells; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Software	1994
Standard binding and functional assays related to medications development division testing for potential cocaine and opiate narcotic treatment medications. NIDA research monograph, 1998, Volume: 178 Topics: Animals; Aorta, Thoracic; Cocaine; Cyclic AMP; Electric Stimulation; Guinea Pigs; Humans; Ileum; In Vitro Techniques; Male; Mice; Muscle, Smooth; Opioid-Related Disorders; Rats; Receptors, Dopamine; Receptors, Opioid; Receptors, Serotonin; Substance-Related Disorders	1998
Opioid and cannabinoid receptor inhibition of adenylyl cyclase in brain. Annals of the New York Academy of Sciences, 1992, Jun-28, Volume: 654 Topics: Adenylyl Cyclase Inhibitors; Adenylyl Imidodiphosphate; Analgesics; Animals; Brain; Cannabinoids; Cells, Cultured; Colforsin; Cyclic AMP; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Male; Neurons; Protein Precursors; Rats; Rats, Inbred Strains; Receptors, Cannabinoid; Receptors, Drug; Receptors, Opioid; RNA, Messenger	1992
Characterization of opioid receptors mediating stimulation of adenylate cyclase activity in rat olfactory bulb. Molecular pharmacology, 1992, Volume: 42, Issue:1 Topics: Adenylyl Cyclases; Animals; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Enzyme Activation; Male; Narcotic Antagonists; Olfactory Bulb; Oligopeptides; Opioid Peptides; Rats; Rats, Inbred Strains; Receptors, Opioid	1992
delta-Opioid receptor binding in mouse brain: evidence for heterogeneous binding sites. European journal of pharmacology, 1992, Jun-05, Volume: 216, Issue:2 Topics: Animals; Binding, Competitive; Brain Chemistry; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Male; Membranes; Mice; Naltrexone; Narcotic Antagonists; Receptors, Opioid, delta	1992
Differential antagonism of opioid delta antinociception by [D-Ala2,Leu5,Cys6]enkephalin and naltrindole 5'-isothiocyanate: evidence for delta receptor subtypes. The Journal of pharmacology and experimental therapeutics, 1991, Volume: 257, Issue:3 Topics: Analgesics; Animals; Dose-Response Relationship, Drug; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Injections, Intraventricular; Isothiocyanates; Male; Mice; Mice, Inbred ICR; Morphinans; Naltrexone; Narcotic Antagonists; Oligopeptides; Receptors, Opioid; Receptors, Opioid, delta; Thiocyanates	1991
[Periodic and aperiodic oscillations in neuropeptide-binding receptors in cultured cells]. Doklady Akademii nauk SSSR, 1991, Volume: 320, Issue:2 Topics: Animals; Cells, Cultured; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Kinetics; Neuropeptides; Rats; Receptors, Neurotransmitter; Receptors, Opioid; Receptors, Opioid, delta	1991
Role of peripheral mu, delta and kappa opioid receptors in opioid-induced inhibition of gastrointestinal transit in rats. The Journal of pharmacology and experimental therapeutics, 1990, Volume: 254, Issue:1 Topics: Animals; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Gastrointestinal Motility; Male; Oligopeptides; Rats; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu	1990
Selective inhibitory effects of ethylketocyclazocine on reflex pathways to the external urethral sphincter of the cat. The Journal of pharmacology and experimental therapeutics, 1989, Volume: 248, Issue:3 Topics: Animals; Cats; Cyclazocine; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Ethylketocyclazocine; Female; Morphine; Naloxone; Oligopeptides; Receptors, Opioid; Receptors, Opioid, kappa; Reflex; Urethra; Urinary Bladder; Urinary Incontinence	1989
Dermorphin gene sequence peptide with high affinity and selectivity for delta-opioid receptors. The Journal of biological chemistry, 1989, Feb-25, Volume: 264, Issue:6 Topics: Analgesics, Opioid; Animals; Binding, Competitive; Brain; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Oligopeptides; Opioid Peptides; Protein Conformation; Rats; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Synaptosomes	1989
A quantitative study of [3H]D-Ala2-D-Leu5-enkephalin binding to rat brain membranes. Evidence that oxymorphone is a noncompetitive inhibitor of the lower affinity delta-binding site. Molecular pharmacology, 1985, Volume: 27, Issue:3 Topics: Animals; Autoradiography; Brain; Chlorides; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Guanosine Triphosphate; Hydromorphone; Male; Manganese; Manganese Compounds; Mathematics; Membranes; Oligopeptides; Oxymorphone; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Sodium Chloride	1985
Selective effects of ethanol on opiate receptor subtypes in brain. Neuropharmacology, 1987, Volume: 26, Issue:10 Topics: Animals; Benzomorphans; Binding, Competitive; Brain Chemistry; Dopamine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Ethanol; In Vitro Techniques; Limbic System; Male; Mice; Mice, Inbred C57BL; Narcotics; Oligopeptides; Receptors, Opioid	1987
New approaches to the evaluation of opioid agonists and antagonists upon the isolated, electrically stimulated mouse vas deferens preparation. NIDA research monograph, 1987, Volume: 76 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Benzodiazepines; Benzomorphans; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Male; Mice; Mice, Inbred ICR; Naltrexone; Narcotic Antagonists; Oligopeptides; Pyrrolidines; Receptors, Opioid; Vas Deferens	1987
Effect of ethanol on the binding of conformationally rigid and labile ligands of opioid receptors to rat brain membranes. Biochemical pharmacology, 1988, Jun-01, Volume: 37, Issue:11 Topics: Animals; Brain; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Ethanol; In Vitro Techniques; Male; Naltrexone; Oligopeptides; Protein Conformation; Rats; Rats, Inbred Strains; Receptors, Opioid	1988
ADP-ribosylation with pertussis toxin modulates the GTP-sensitive opioid ligand binding in digitonin-soluble extracts of rat brain membranes. Journal of neurochemistry, 1988, Volume: 51, Issue:1 Topics: Adenosine Diphosphate Ribose; Animals; Brain; Cell Membrane; Digitonin; Electrophoresis, Polyacrylamide Gel; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Etorphine; GTP-Binding Proteins; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Kinetics; Naloxone; Oligopeptides; Pertussis Toxin; Rats; Receptors, Opioid; Sodium; Solubility; Virulence Factors, Bordetella	1988
Nor-binaltorphimine, a highly selective kappa-opioid antagonist in analgesic and receptor binding assays. The Journal of pharmacology and experimental therapeutics, 1988, Volume: 246, Issue:1 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesia; Animals; Cyclazocine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Ethylketocyclazocine; Guinea Pigs; Male; Mice; Morphine; Naltrexone; Oligopeptides; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, kappa	1988
Comparison of the antinociceptive action of mu and delta opioid receptor ligands in the periaqueductal gray matter, medial and paramedial ventral medulla in the rat as studied by the microinjection technique. Brain research, 1986, May-07, Volume: 372, Issue:2 Topics: Analgesics, Opioid; Animals; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Fentanyl; Male; Medulla Oblongata; Morphine; Naloxone; Oligopeptides; Periaqueductal Gray; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Sufentanil	1986
Opiate binding in calf thalamic membranes: a selective mu 1 binding assay. Molecular pharmacology, 1988, Volume: 34, Issue:3 Topics: Animals; Cattle; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Hydrogen-Ion Concentration; In Vitro Techniques; Naloxone; Oligopeptides; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Thalamus	1988
Evidence that the delta-selective alkylating agent, fit, alters the mu-noncompetitive opiate delta binding site. Neuropeptides, 1985, Volume: 6, Issue:3 Topics: Affinity Labels; Animals; Chemical Phenomena; Chemistry; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Fentanyl; In Vitro Techniques; Isothiocyanates; Oligopeptides; Rats; Receptors, Opioid; Receptors, Opioid, delta	1985
Interaction of opiates with opioid binding sites in the bovine adrenal medulla: I. Interaction with delta and mu sites. Journal of neurochemistry, 1985, Volume: 45, Issue:3 Topics: Adrenal Medulla; Animals; Binding Sites; Cattle; Cesium; Chlorides; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Enkephalins; Ethylmaleimide; Kinetics; Lithium; Narcotics; Oligopeptides; Phospholipases A; Potassium; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Sodium; Stereoisomerism	1985
Interaction of opiates with opioid binding sites in the bovine adrenal medulla: II. Interaction with kappa sites. Journal of neurochemistry, 1985, Volume: 45, Issue:3 Topics: Adrenal Medulla; Animals; Benzomorphans; Binding Sites; Calcium; Cattle; Cyclazocine; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Ethylketocyclazocine; Ethylmaleimide; Etorphine; Guinea Pigs; Kinetics; Lithium; Manganese; Narcotics; Oligopeptides; Phospholipases A; Potassium; Receptors, Opioid; Receptors, Opioid, kappa; Sodium; Stereoisomerism	1985
Sulfonic acid enkephalin: binding specificity to rat brain opiate receptors. Neuropeptides, 1985, Volume: 6, Issue:4 Topics: Animals; Binding, Competitive; Brain; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Kinetics; Male; Oligopeptides; Rats; Rats, Inbred Strains; Receptors, Opioid	1985
Receptors for opioid peptides in the guinea-pig ileum. The Journal of pharmacology and experimental therapeutics, 1985, Volume: 235, Issue:2 Topics: Alkylation; Animals; Dose-Response Relationship, Drug; Electric Stimulation; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Enkephalins; Guinea Pigs; Ileum; Male; Mice; Naloxone; Naltrexone; Oligopeptides; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Vas Deferens	1985
Opiate-induced seizures: a study of mu and delta specific mechanisms. Experimental neurology, 1986, Volume: 93, Issue:2 Topics: Animals; Electroencephalography; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Morphine; Narcotics; Oligopeptides; Rats; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Seizures	1986
Sodium regulation of agonist binding at opioid receptors. II. Effects of sodium replacement on opioid binding in guinea pig cortical membranes. Molecular pharmacology, 1986, Volume: 30, Issue:2 Topics: Animals; Cell Membrane; Cerebral Cortex; Cyclazocine; Diprenorphine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Ethylketocyclazocine; Etorphine; Guinea Pigs; Male; Oligopeptides; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Sodium	1986
[D-Pen2,D-Pen5]enkephalin (DPDPE): a delta-selective enkephalin with low affinity for mu 1 opiate binding sites. European journal of pharmacology, 1986, Sep-09, Volume: 128, Issue:3 Topics: Animals; Brain Chemistry; Cattle; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; In Vitro Techniques; Oligopeptides; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu	1986
Role of mu and delta receptors in the supraspinal and spinal analgesic effects of [D-Pen2, D-Pen5]enkephalin in the mouse. The Journal of pharmacology and experimental therapeutics, 1987, Volume: 241, Issue:2 Topics: Analgesia; Anesthesia, Spinal; Animals; Drug Synergism; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Male; Mice; Morphine; Oligopeptides; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu	1987
Differential maturation of mu and delta opioid receptors in the chick embryonic brain. Neurochemical research, 1987, Volume: 12, Issue:3 Topics: Animals; Brain; Chick Embryo; Dihydromorphine; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Levorphanol; Oligopeptides; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu	1987
DSLET (D-ser2-leu5-enkephalin-Thr6) produces analgesia on the hot plate by mechanisms largely different from DAGO and morphine-like opioids. Life sciences, 1987, Jul-27, Volume: 41, Issue:4 Topics: Analgesics; Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Mice; Mice, Inbred Strains; Oligopeptides; Species Specificity; Structure-Activity Relationship	1987
Effect of beta-FNA on opiate delta receptor binding. Journal of neurochemistry, 1984, Volume: 43, Issue:4 Topics: Animals; Brain; Cell Membrane; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Naloxone; Naltrexone; Oligopeptides; Protein Conformation; Rats; Receptors, Opioid	1984
Interaction of naloxone with mu- and delta-opioid agonists on the respiration of rats. European journal of pharmacology, 1983, Feb-18, Volume: 87, Issue:2-3 Topics: Animals; D-Ala(2),MePhe(4),Met(0)-ol-enkephalin; Depression, Chemical; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Enkephalins; Female; Injections, Intraventricular; Male; Morphine; Naloxone; Narcotics; Oligopeptides; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Respiration; Time Factors	1983
Bis-penicillamine enkephalins possess highly improved specificity toward delta opioid receptors. Proceedings of the National Academy of Sciences of the United States of America, 1983, Volume: 80, Issue:19 Topics: Animals; Binding, Competitive; Biological Assay; Brain; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Isomerism; Kinetics; Muscle Contraction; Naloxone; Oligopeptides; Rats; Receptors, Opioid; Receptors, Opioid, delta; Structure-Activity Relationship	1983
A comparative study in rats of the respiratory depression and analgesia induced by mu- and delta-opioid agonists. European journal of pharmacology, 1984, Mar-16, Volume: 99, Issue:1 Topics: Analgesia; Animals; D-Ala(2),MePhe(4),Met(0)-ol-enkephalin; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Female; Male; Morphine; Oligopeptides; Rats; Rats, Inbred Strains; Respiration	1984
The inhibitory effect of opioid peptides and morphine applied intrathecally and intracerebroventricularly on the micturition reflex in the cat. Brain research, 1984, Apr-23, Volume: 298, Issue:1 Topics: Animals; Cats; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Enkephalins; Female; Morphine; Naloxone; Oligopeptides; Reflex; Thiorphan; Tiopronin; Urination	1984
Anti-idiotypic antibodies: a useful alternative for studying the biochemical expression of mu/delta opioid binding sites in mammalian brain. Journal of neuroimmunology, 1995, Volume: 62, Issue:2 Topics: Animals; Antibodies, Anti-Idiotypic; Binding Sites; Brain Chemistry; Cyclic AMP; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Immunoblotting; Mice; Mice, Inbred BALB C; Rats; Rats, Wistar; Receptors, Opioid, delta; Receptors, Opioid, mu; Tumor Cells, Cultured	1995
Evidence for functional delta-opiate receptors in the rat intestine. The Journal of pharmacy and pharmacology, 1994, Volume: 46, Issue:10 Topics: Acetylcholine; Animals; Cricetinae; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Female; In Vitro Techniques; Jejunum; Male; Mice; Muscle Contraction; Muscle, Smooth; Naltrexone; Rats; Rats, Wistar; Receptors, Opioid, delta	1994
[Participation of central opiate receptors in the pathogenesis of adrenal arrhythmias]. Biulleten' eksperimental'noi biologii i meditsiny, 1994, Volume: 118, Issue:9 Topics: Adrenal Gland Diseases; Animals; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Male; Rats; Rats, Wistar; Receptors, Opioid	1994
Analysis of delta-opioid receptor activities stably expressed in CHO cell lines: function of receptor density? The Journal of pharmacology and experimental therapeutics, 1994, Volume: 271, Issue:3 Topics: Adenylyl Cyclase Inhibitors; Animals; Base Sequence; CHO Cells; Cricetinae; Cyclic AMP; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Molecular Sequence Data; Receptors, Opioid, delta; RNA, Messenger; Transfection	1994
The peristaltic reflex in the rat ileum: evidence for functional mu- and delta-opiate receptors. The Journal of pharmacy and pharmacology, 1995, Volume: 47, Issue:8 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Antidiarrheals; Diphenoxylate; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Ileum; Linear Models; Loperamide; Morphine; Peristalsis; Pyrrolidines; Rats; Receptors, Opioid, delta; Receptors, Opioid, mu	1995
Characterization of supraspinal antinociceptive actions of opioid delta agonists in the rat. Pain, 1995, Volume: 62, Issue:3 Topics: Animals; Cerebral Ventricles; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Hot Temperature; Injections, Intraventricular; Male; Medulla Oblongata; Morphine; Nociceptors; Oligopeptides; Pain Measurement; Periaqueductal Gray; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Reticular Formation	1995
The antiproliferative effect of opioid receptor agonists on the T47D human breast cancer cell line, is partially mediated through opioid receptors. European journal of pharmacology, 1996, Jan-25, Volume: 296, Issue:2 Topics: Adenocarcinoma; Amino Acid Sequence; Binding Sites; Breast Neoplasms; Cell Division; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Ethylketocyclazocine; Etorphine; Humans; Molecular Sequence Data; Morphine; Narcotic Antagonists; Opioid Peptides; Receptors, Opioid; Tumor Cells, Cultured	1996
The mu1 and mu2 opioid receptor binding of ketobemidone, norketobemidone and 3-dimethylamino-1,1-diphenylbutene. Pharmacology & toxicology, 1996, Volume: 79, Issue:2 Topics: Allylamine; Analgesics, Opioid; Animals; Binding, Competitive; Cattle; Caudate Nucleus; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Humans; Isonipecotic Acids; Meperidine; Parasympatholytics; Phenols; Receptors, Opioid, delta; Receptors, Opioid, mu	1996
Opioid regulation of the mouse delta-opioid receptor expressed in human embryonic kidney 293 cells. Molecular pharmacology, 1997, Volume: 52, Issue:2 Topics: Adenylyl Cyclases; Animals; Antibodies, Monoclonal; Cell Line; Colforsin; Cyclic AMP; Down-Regulation; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Etorphine; GTP-Binding Proteins; Humans; Methadone; Mice; Morphine; Point Mutation; Radioligand Assay; Receptors, Opioid, delta; Signal Transduction; Structure-Activity Relationship	1997
Mutagenesis of the mouse delta opioid receptor converts (-)-buprenorphine from a partial agonist to an antagonist. The Journal of pharmacology and experimental therapeutics, 1998, Volume: 284, Issue:1 Topics: Analgesics, Opioid; Animals; Buprenorphine; Cells, Cultured; Cyclic AMP; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Mice; Mutagenesis; Naltrexone; Narcotic Antagonists; Receptors, Opioid, delta	1998
Binding properties of C-truncated delta opioid receptors. Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1997, Volume: 18, Issue:4 Topics: Animals; Binding Sites; CHO Cells; Cricetinae; Diprenorphine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Peptide Fragments; Radioligand Assay; Receptors, Opioid, delta; Receptors, Opioid, mu	1997
[Effects of opioid peptides on ischemic myocardial arrhythmias during laser irradiation and disturbed heart sympathetic innervation]. Biulleten' eksperimental'noi biologii i meditsiny, 1999, Volume: 127, Issue:4 Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cats; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Female; Heart; Lasers; Male; Myocardial Ischemia; Myocardium; Opioid Peptides; Receptors, Opioid; Sympathectomy	1999