enkephalin, ser(2), leu(5), thr(6)- and bw 373u86

enkephalin, ser(2), leu(5), thr(6)- has been researched along with bw 373u86 in 2 studies

Compound Research Comparison

Studies (enkephalin, ser(2), leu(5), thr(6)-)	Trials (enkephalin, ser(2), leu(5), thr(6)-)	Recent Studies (post-2010) (enkephalin, ser(2), leu(5), thr(6)-)	Studies (bw 373u86)	Trials (bw 373u86)	Recent Studies (post-2010) (bw 373u86)
224	0	5	80	0	4

Protein Interaction Comparison

Protein	Taxonomy	bw 373u86 (IC50)
Delta-type opioid receptor	Rattus norvegicus (Norway rat)	0.02
Mu-type opioid receptor	Rattus norvegicus (Norway rat)	0.9346
Mu-type opioid receptor	Homo sapiens (human)	0.0021
Delta-type opioid receptor	Homo sapiens (human)	0.0002
Kappa-type opioid receptor	Cavia porcellus (domestic guinea pig)	0.0003
Kappa-type opioid receptor	Homo sapiens (human)	0.02

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (50.00)	18.2507
2000's	1 (50.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Bernard, D; Coop, A; MacKerell, AD	1
Chang, KJ; Comer, SD; De Costa, BR; Hoenicke, EM; McNutt, RW; Mosberg, HI; Sable, AI; Woods, JH	1

Other Studies

2 other study(ies) available for enkephalin, ser(2), leu(5), thr(6)- and bw 373u86

Article	Year
Quantitative conformationally sampled pharmacophore for delta opioid ligands: reevaluation of hydrophobic moieties essential for biological activity. Journal of medicinal chemistry, 2007, Apr-19, Volume: 50, Issue:8 Topics: Animals; Cell Line, Tumor; Enkephalin, Leucine; Hydrophobic and Hydrophilic Interactions; Ligands; Models, Molecular; Molecular Conformation; Phenylalanine; Quantitative Structure-Activity Relationship; Rats; Receptors, Opioid, delta	2007
Convulsive effects of systemic administration of the delta opioid agonist BW373U86 in mice. The Journal of pharmacology and experimental therapeutics, 1993, Volume: 267, Issue:2 Topics: Amino Acid Sequence; Animals; Anticonvulsants; Benzamides; Dose-Response Relationship, Drug; Drug Tolerance; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalins; Kindling, Neurologic; Male; Mice; Mice, Inbred Strains; Midazolam; Molecular Sequence Data; Naltrexone; Pentylenetetrazole; Piperazines; Receptors, Opioid, delta; Receptors, Opioid, mu; Seizures	1993

Article

Year

Quantitative conformationally sampled pharmacophore for delta opioid ligands: reevaluation of hydrophobic moieties essential for biological activity.

Journal of medicinal chemistry, 2007, Apr-19, Volume: 50, Issue:8

Topics: Animals; Cell Line, Tumor; Enkephalin, Leucine; Hydrophobic and Hydrophilic Interactions; Ligands; Models, Molecular; Molecular Conformation; Phenylalanine; Quantitative Structure-Activity Relationship; Rats; Receptors, Opioid, delta

2007

Convulsive effects of systemic administration of the delta opioid agonist BW373U86 in mice.

The Journal of pharmacology and experimental therapeutics, 1993, Volume: 267, Issue:2

Topics: Amino Acid Sequence; Animals; Anticonvulsants; Benzamides; Dose-Response Relationship, Drug; Drug Tolerance; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalins; Kindling, Neurologic; Male; Mice; Mice, Inbred Strains; Midazolam; Molecular Sequence Data; Naltrexone; Pentylenetetrazole; Piperazines; Receptors, Opioid, delta; Receptors, Opioid, mu; Seizures

1993