Page last updated: 2024-09-04

enkephalin, pen(2,5)-4-chloro-phe(4)- and naloxone

enkephalin, pen(2,5)-4-chloro-phe(4)- has been researched along with naloxone in 2 studies

Compound Research Comparison

Studies
(enkephalin, pen(2,5)-4-chloro-phe(4)-)
Trials
(enkephalin, pen(2,5)-4-chloro-phe(4)-)
Recent Studies (post-2010)
(enkephalin, pen(2,5)-4-chloro-phe(4)-)
Studies
(naloxone)
Trials
(naloxone)
Recent Studies (post-2010) (naloxone)
120120,1341,2573,321

Protein Interaction Comparison

ProteinTaxonomyenkephalin, pen(2,5)-4-chloro-phe(4)- (IC50)naloxone (IC50)
Cytochrome P450 2D6Homo sapiens (human)2
Delta-type opioid receptorMus musculus (house mouse)0.043
Delta-type opioid receptorRattus norvegicus (Norway rat)0.0219
Mu-type opioid receptorRattus norvegicus (Norway rat)0.0019
Kappa-type opioid receptorRattus norvegicus (Norway rat)0.0019
Mu-type opioid receptorHomo sapiens (human)0.0397
Delta-type opioid receptorHomo sapiens (human)0.1896
Kappa-type opioid receptorCavia porcellus (domestic guinea pig)0.05
Kappa-type opioid receptorHomo sapiens (human)0.0795
Mu-type opioid receptorMus musculus (house mouse)0.0154
Mu-type opioid receptorCavia porcellus (domestic guinea pig)0.0089
Beta-2 adrenergic receptorCavia porcellus (domestic guinea pig)0.0055

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Burks, TF; Davis, TP; Greene, DL; Hersh, LB; Hruby, VJ; Kramer, TH; Sharma, SD; Weber, SJ; Yamamura, HI1
Aloyo, VJ; Battisi, WP; Pazdalski, PS1

Other Studies

2 other study(ies) available for enkephalin, pen(2,5)-4-chloro-phe(4)- and naloxone

ArticleYear
Distribution and analgesia of [3H][D-Pen2, D-Pen5]enkephalin and two halogenated analogs after intravenous administration.
    The Journal of pharmacology and experimental therapeutics, 1991, Volume: 259, Issue:3

    Topics: Analgesics; Animals; Binding, Competitive; Drug Stability; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Indoles; Injections, Intravenous; Male; Mice; Mice, Inbred Strains; Morphinans; Naloxone; Naltrexone; Neprilysin; Tissue Distribution; Tritium

1991
Characterization and localization of delta opioid binding sites in the bovine pineal gland.
    Journal of pineal research, 1993, Volume: 15, Issue:2

    Topics: Animals; Autoradiography; Binding Sites; Cattle; Cell Membrane; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Ligands; Naloxone; Pineal Gland; Receptors, Opioid, delta

1993