Compounds > enkephalin, pen(2,5)-4-chloro-phe(4)-

Page last updated: 2024-09-04

enkephalin, pen(2,5)-4-chloro-phe(4)- and enkephalin, leucine

enkephalin, pen(2,5)-4-chloro-phe(4)- has been researched along with enkephalin, leucine in 10 studies

Compound Research Comparison

Studies (enkephalin, pen(2,5)-4-chloro-phe(4)-)	Trials (enkephalin, pen(2,5)-4-chloro-phe(4)-)	Recent Studies (post-2010) (enkephalin, pen(2,5)-4-chloro-phe(4)-)	Studies (enkephalin, leucine)	Trials (enkephalin, leucine)	Recent Studies (post-2010) (enkephalin, leucine)
12	0	1	11,524	80	754

Protein Interaction Comparison

Protein	Taxonomy	enkephalin, pen(2,5)-4-chloro-phe(4)- (IC50)	enkephalin, leucine (IC50)
Delta-type opioid receptor	Mus musculus (house mouse)		0.0142
Kappa-type opioid receptor	Mus musculus (house mouse)		0.0417
Mu-type opioid receptor	Homo sapiens (human)		9.5
Mu-type opioid receptor	Mus musculus (house mouse)		0.0308
Mu-type opioid receptor	Cavia porcellus (domestic guinea pig)		0.246

Research

Studies (10)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	7 (70.00)	18.2507
2000's	2 (20.00)	29.6817
2010's	1 (10.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Burks, TF; Davis, TP; Greene, DL; Hersh, LB; Hruby, VJ; Kramer, TH; Sharma, SD; Weber, SJ; Yamamura, HI	1
Burks, TF; Davis, P; Hruby, VJ; Knapp, RJ; Shimohigashi, Y; Toth, G; Vaughn, LK; Wire, WS; Yamamura, HI	1
Babin, E; Fang, L; Hruby, VJ; Knapp, RJ; Li, X; Malatynska, E; Nguyen, M; Roeske, WR; Santoro, G; Varga, EV	1
Aloyo, VJ; Battisi, WP; Pazdalski, PS	1
Kübler, W; Mura, RA; Niroomand, F; Piacentini, L	1
Calderon, SN; Hruby, VJ; Kawai, K; Knapp, RJ; Landsman, RS; Li, X; Malatynska, E; Mizusura, A; Nagase, H; Rice, K; Roeske, WR; Stropova, D; Varga, EV; Yamamura, HI; Zalewska, T	1
Appleyard, SM; Davis, TP; Hruby, VJ; Knapp, RJ; Lipkowski, AW; Misicka, A; Slaninova, J; Weber, SJ; Yamamura, HI	1
Burkey, TH; Hosohata, Y; Hruby, VJ; Kovelowski, CJ; Lai, J; Ossipov, MH; Porreca, F; Rice, KC; Roeske, WR; Sora, I; Uhl, GR; Vanderah, TW; Yamamura, HI; Zhang, X	1
Amico, JA; Brown, DC; Perkowski, SZ; Shofer, F	1
Hadjiconstantinou, M; McCarthy, MJ; Neff, NH; Zhang, H	1

Other Studies

10 other study(ies) available for enkephalin, pen(2,5)-4-chloro-phe(4)- and enkephalin, leucine

Article	Year
Distribution and analgesia of [3H][D-Pen2, D-Pen5]enkephalin and two halogenated analogs after intravenous administration. The Journal of pharmacology and experimental therapeutics, 1991, Volume: 259, Issue:3 Topics: Analgesics; Animals; Binding, Competitive; Drug Stability; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Indoles; Injections, Intravenous; Male; Mice; Mice, Inbred Strains; Morphinans; Naloxone; Naltrexone; Neprilysin; Tissue Distribution; Tritium	1991
Differentiation between rat brain and mouse vas deferens delta opioid receptors. European journal of pharmacology, 1990, Feb-20, Volume: 177, Issue:1-2 Topics: Animals; Brain; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; In Vitro Techniques; Male; Mice; Mice, Inbred ICR; Muscle, Smooth; Organ Specificity; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Species Specificity; Vas Deferens	1990
Identification of a human delta opioid receptor: cloning and expression. Life sciences, 1994, Volume: 54, Issue:25 Topics: Amino Acid Sequence; Animals; Base Sequence; Cell Line; Cloning, Molecular; Consensus Sequence; Enkephalins; Humans; Mice; Molecular Sequence Data; Naltrexone; Narcotic Antagonists; Oligopeptides; Open Reading Frames; Receptors, Opioid, delta; Sequence Alignment; Transfection	1994
Characterization and localization of delta opioid binding sites in the bovine pineal gland. Journal of pineal research, 1993, Volume: 15, Issue:2 Topics: Animals; Autoradiography; Binding Sites; Cattle; Cell Membrane; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Ligands; Naloxone; Pineal Gland; Receptors, Opioid, delta	1993
Opioid receptor agonists activate pertussis toxin-sensitive G proteins and inhibit adenylyl cyclase in canine cardiac sarcolemma. Naunyn-Schmiedeberg's archives of pharmacology, 1996, Volume: 354, Issue:5 Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Analgesics; Analysis of Variance; Animals; Diprenorphine; Dogs; Dose-Response Relationship, Drug; Dynorphins; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; GTP Phosphohydrolases; GTP-Binding Proteins; Myocardium; Naltrexone; Narcotic Antagonists; Pertussis Toxin; Sarcolemma; Virulence Factors, Bordetella	1996
The third extracellular loop of the human delta-opioid receptor determines the selectivity of delta-opioid agonists. Molecular pharmacology, 1996, Volume: 50, Issue:6 Topics: Amino Acid Sequence; Animals; COS Cells; Enkephalins; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligopeptides; Quinolines; Receptors, Opioid, delta; Recombinant Fusion Proteins	1996
[125I-Tyr1]biphalin binding to opioid receptors of rat brain and NG108-15 cell membranes. Life sciences, 1998, Volume: 62, Issue:14 Topics: Animals; Brain; Cell Line; Cell Membrane; Enkephalins; Iodine Radioisotopes; Morphine; Naltrexone; Narcotic Antagonists; Oligopeptides; Radioligand Assay; Rats; Receptors, Opioid	1998
delta-Opioid receptor agonists produce antinociception and [35S]GTPgammaS binding in mu receptor knockout mice. European journal of pharmacology, 2000, Feb-04, Volume: 388, Issue:3 Topics: Analgesics, Opioid; Animals; Benzamides; Brain; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Guanosine 5'-O-(3-Thiotriphosphate); In Vitro Techniques; Membranes; Mice; Mice, Knockout; Oligopeptides; Pain Measurement; Piperazines; Protein Binding; Radioligand Assay; Receptors, Opioid, delta; Receptors, Opioid, mu; Spinal Cord	2000
Effect of centrally administered opioid receptor agonists on CSF and plasma oxytocin concentrations in dogs. American journal of veterinary research, 2001, Volume: 62, Issue:4 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Cross-Over Studies; Dogs; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Injections, Spinal; Male; Morphine; Oxytocin; Random Allocation; Receptors, Opioid	2001
Desensitization of δ-opioid receptors in nucleus accumbens during nicotine withdrawal. Psychopharmacology, 2011, Volume: 213, Issue:4 Topics: Adenylyl Cyclases; Animals; Autoradiography; Enkephalins; Male; Mice; Nicotine; Nucleus Accumbens; Protein Binding; Receptors, Opioid, delta; RNA, Messenger; Substance Withdrawal Syndrome; Time Factors; Tobacco Use Disorder	2011