enkephalin, met(2)-pronh2(5)- has been researched along with naloxone in 29 studies
| Studies (enkephalin, met(2)-pronh2(5)-) | Trials (enkephalin, met(2)-pronh2(5)-) | Recent Studies (post-2010) (enkephalin, met(2)-pronh2(5)-) | Studies (naloxone) | Trials (naloxone) | Recent Studies (post-2010) (naloxone) |
|---|---|---|---|---|---|
| 65 | 0 | 1 | 20,134 | 1,257 | 3,321 |
| Protein | Taxonomy | enkephalin, met(2)-pronh2(5)- (IC50) | naloxone (IC50) |
|---|---|---|---|
| Cytochrome P450 2D6 | Homo sapiens (human) | 2 | |
| Delta-type opioid receptor | Mus musculus (house mouse) | 0.043 | |
| Delta-type opioid receptor | Rattus norvegicus (Norway rat) | 0.0219 | |
| Mu-type opioid receptor | Rattus norvegicus (Norway rat) | 0.0019 | |
| Kappa-type opioid receptor | Rattus norvegicus (Norway rat) | 0.0019 | |
| Mu-type opioid receptor | Homo sapiens (human) | 0.0397 | |
| Delta-type opioid receptor | Homo sapiens (human) | 0.1896 | |
| Kappa-type opioid receptor | Cavia porcellus (domestic guinea pig) | 0.05 | |
| Kappa-type opioid receptor | Homo sapiens (human) | 0.0795 | |
| Mu-type opioid receptor | Mus musculus (house mouse) | 0.0154 | |
| Mu-type opioid receptor | Cavia porcellus (domestic guinea pig) | 0.0089 | |
| Beta-2 adrenergic receptor | Cavia porcellus (domestic guinea pig) | 0.0055 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (55.17) | 18.7374 |
| 1990's | 11 (37.93) | 18.2507 |
| 2000's | 2 (6.90) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Csernus, V; Gerendai, I; Nemeskéri, A | 2 |
| Barthó, L; Ernst, R; Faulstroh, K; Pethö, G; Pierau, FK; Sann, H | 1 |
| Ordög, T; Vértes, M; Vértes, Z | 1 |
| Barthó, L; Ernst, R; Pierau, FK; Sann, H | 1 |
| Halász, B; Molnár, J | 1 |
| Gáti, T; Székely, JI; Szombath, D; Till, M | 1 |
| Gyires, K | 1 |
| Endröczi, E; Hepp, J; Korányi, L; Walentin, S | 1 |
| Joffe, S; Murphy, RF; Sperling, MA; Werther, GA | 1 |
| Gamse, R; Saria, A | 1 |
| Gogolak, I; Gotoh, F; Sándor, P; Tanahashi, N; Tomita, M | 1 |
| Barthó, L | 1 |
| Gáti, T; Rábai, K; Székely, JI; Szombath, D; Till, M | 1 |
| Arndt, JO; Inoue, K; Nashan, B | 1 |
| Barthó, L; Holzer, P; Lembeck, F; Lippe, IT | 1 |
| Berzétei, IP; Csaba, G; Dobozy, O; Kurgyis, J; Rónai, AZ | 1 |
| Artal, R; Joffe, S; Sperling, MA; Werther, GA | 1 |
| Halász, B; Nagy, G; Takács, L | 1 |
| Benedek, G; Székely, JI; Szikszay, M | 1 |
| Halász, B; Köves, K; Marton, J; Molnár, J | 1 |
| Kovács, S; Melegh, G; Vértes, M; Vértes, Z | 1 |
| Dhorajiwala, J; Ipp, E; Moossa, AR; Pugh, W; Rubenstein, AH | 1 |
| Danitz, B; Jaszlits, L; Kauthny, K; Kósa, E; Székely, JI; Tardos, L | 1 |
| Környei, JL; Kovács, S; Vértes, M; Vértes, Z | 1 |
| Környei, JL; Kovács, S; Oszter, A; Vértes, M; Vértes, Z | 1 |
| Környei, JL; Kovács, KA; Oszter, A; Rao, CV; Vértes, M; Vértes, Z | 1 |
| Környei, JL; Kovács, KA; Kovács, S; Oszter, A; Sándor, A; Vértes, M; Vértes, Z | 1 |
| Környei, JL; Lengyel, F; Oszter, A; Sumegi, B; Vértes, M; Vértes, Z | 1 |
29 other study(ies) available for enkephalin, met(2)-pronh2(5)- and naloxone
| Article | Year |
|---|---|
Vasectomy modulates the local effect of intratesticular opioids on the gonad of immature rats.
Topics: Animals; Enkephalin, Methionine; Injections; Male; Naloxone; Organ Size; Rats; Rats, Sprague-Dawley; Testis; Testosterone; Vasectomy | 1992 |
An opioid peptide inhibits capsaicin-sensitive vasodilatation in the pig's skin.
Topics: Animals; Capsaicin; Electric Stimulation; Enkephalin, Methionine; Guanethidine; Microcirculation; Naloxone; Neurons; Skin; Swine; Tetrodotoxin; Vasodilation | 1992 |
Inhibition of oestradiol-induced DNA synthesis by opioid peptides in the rat uterus.
Topics: Animals; DNA; Endorphins; Enkephalin, Methionine; Estradiol; Estrogen Antagonists; Female; Male; Naloxone; Ovariectomy; Rats; Rats, Inbred Strains; Uterus | 1992 |
Endogenous opioids and ruthenium red inhibit the flare reaction in the pig skin by different mechanisms.
Topics: Animals; Capsaicin; Enkephalin, Methionine; Hypersensitivity, Immediate; Naloxone; Regional Blood Flow; Ruthenium Red; Skin; Skin Physiological Phenomena; Swine; Vasodilation | 1991 |
Mesencephalic sites of action of an enkephalin analogue (D-Met2, Pro5)-enkephalinamide and naloxone on the anterior pituitary of male rats.
Topics: Animals; Enkephalin, Methionine; In Vitro Techniques; Injections; Male; Mesencephalon; Naloxone; Pituitary Gland, Anterior; Pituitary Hormones, Anterior; Rats; Rats, Inbred Strains | 1991 |
Intratesticular injection of [D-Met2-Pro5]enkephalinamide suppresses testosterone secretion of the testis of immature rat.
Topics: Animals; Animals, Newborn; Enkephalin, Methionine; Female; In Vitro Techniques; Injections; Male; Naloxone; Orchiectomy; Pregnancy; Rats; Testis; Testosterone | 1990 |
Naloxone-insensitive modulation of gastric acid output by [D-Met2,Pro5]enkephalinamide in rats.
Topics: Animals; Enkephalin, Methionine; Gastric Acid; Male; Morphine; Naloxone; Pylorus; Rats; Rats, Inbred Strains; Stomach Ulcer | 1990 |
The effect of different opiates on acidified ethanol-induced gastric lesions in rats.
Topics: Animals; Benzomorphans; Enkephalin, Methionine; Ethanol; Morphine; Naloxone; Narcotics; Rats; Stomach Ulcer | 1990 |
Changes of dipeptidyl peptidase (DP IV) activity in the T lymphocytes of rats following administration of ACTH, dexamethasone and opiates.
Topics: Adrenocorticotropic Hormone; Animals; Dexamethasone; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Enkephalin, Methionine; Male; Morphine; Naloxone; Rats; Rats, Inbred Strains; Stress, Physiological; T-Lymphocytes | 1989 |
The regulation of basal pancreatic polypeptide levels in dogs.
Topics: Animals; Dogs; Enkephalin, Methionine; Female; Glucagon; Insulin; Naloxone; Pancreatic Polypeptide; Phentolamine; Propranolol; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Receptors, Opioid; Somatostatin | 1987 |
Antidromic vasodilatation in the rat hindpaw measured by laser Doppler flowmetry: pharmacological modulation.
Topics: Adrenergic Fibers; Animals; Capsaicin; Cimetidine; Electric Stimulation; Enkephalin, Methionine; Female; Fentanyl; Hindlimb; Lasers; Male; Naloxone; Pyrilamine; Rats; Regional Blood Flow; Rheology; Skin; Vasodilation | 1987 |
Effects of a stable enkephalin analogue, (D-Met2,Pro5)-enkephalinamide, and naloxone on cortical blood flow and cerebral blood volume in experimental brain ischemia in anesthetized cats.
Topics: Animals; Blood Volume; Brain; Brain Ischemia; Cats; Cerebral Cortex; Cerebrovascular Circulation; Enkephalin, Methionine; Female; Male; Naloxone; Receptors, Opioid; Vascular Resistance | 1986 |
Naloxone-precipitated contractions of the guinea pig ileum made tolerant to a synthetic opioid peptide: evidence against the involvement of capsaicin-sensitive neurones.
Topics: Animals; Capsaicin; Enkephalin, Methionine; Female; Guinea Pigs; Ileum; Male; Muscle Contraction; Muscle, Smooth; Naloxone | 1988 |
Effect of [D-Met2,Pro5]enkephalinamide on gastric ulceration and transmucosal potential difference.
Topics: Analgesics; Animals; Cold Temperature; Enkephalin, Methionine; Evoked Potentials; Gastric Mucosa; Male; Morphine; Naloxone; Rats; Rats, Inbred Strains; Restraint, Physical; Stomach Ulcer; Stress, Psychological | 1988 |
[D-Met2,Pro5]enkephalinamide activates cardioinhibitory efferents in anaesthetized dogs.
Topics: Action Potentials; Anesthesia; Animals; Blood Pressure; Carbon Dioxide; Dogs; Efferent Pathways; Enkephalin, Methionine; Female; Heart; Heart Rate; Male; Naloxone; Vagus Nerve | 1985 |
[D-Met2, Pro5]enkephalinamide and dynorphin-(1-13) inhibit the cholinergic contraction induced in the guinea-pig ileum by substance P.
Topics: Animals; Atropine; Dynorphins; Endorphins; Enkephalin, Methionine; Female; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Naloxone; Parasympathetic Nervous System; Peptide Fragments; Substance P | 1983 |
The effect of neonatal treatment of mice with opioid and dopaminergic agents on the late responsiveness of vasa deferentia to opioids in vitro.
Topics: Animals; Animals, Newborn; Dopamine; Endorphins; Enkephalin, Methionine; Haloperidol; Male; Mice; Morphine; Naloxone; Piribedil; Sulpiride; Time Factors; Vas Deferens | 1984 |
Opiates modulate insulin action in vivo in dogs.
Topics: Animals; Blood Glucose; Dogs; Enkephalin, Methionine; Epinephrine; Female; Glucagon; Hydrocortisone; Insulin; Naloxone | 1984 |
(D-Met2,Pro5) enkephalinamide causes a decrease in plasma prolactin levels of lactating rats continuously suckled and an increase in those deprived of their litter.
Topics: Animals; Enkephalin, Methionine; Female; Kinetics; Lactation; Naloxone; Pregnancy; Prolactin; Rats; Rats, Inbred Strains | 1984 |
Thermoregulatory effects of D-met2-pro5-enkephalinamide.
Topics: Animals; Body Temperature Regulation; Capsaicin; Drug Antagonism; Drug Synergism; Enkephalin, Methionine; Humans; Male; Naloxone; Rats; Rats, Inbred Strains; Restraint, Physical; Stress, Psychological | 1983 |
(D-Met2,Pro5)-enkephalinamide-induced blockade of ovulation and its reversal by naloxone in the rat.
Topics: Animals; Dose-Response Relationship, Drug; Endorphins; Enkephalin, Methionine; Enkephalins; Estrus; Female; Follicle Stimulating Hormone; Luteinizing Hormone; Naloxone; Ovulation; Pregnancy; Rats | 1981 |
Effect of naloxone and D-met2-pro5-enkephalinamide treatment on the DNA synthesis in the developing rat brain.
Topics: Animals; Brain; Cerebellum; DNA; Enkephalin, Methionine; Female; Hypothalamus; Naloxone; Rats; Time Factors | 1982 |
Effects of an enkephalin analog on pancreatic endocrine function and glucose homeostasis in normal and diabetic dogs.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Dogs; Dose-Response Relationship, Drug; Enkephalin, Methionine; Gastric Mucosa; Glucagon; Homeostasis; Naloxone; Pancreas | 1982 |
Cardiovascular effects of a potent opioid peptide, (D-Met2, Pro5)-enkephalinamide.
Topics: Anesthesia; Animals; Blood Pressure; Cats; Enkephalin, Methionine; Female; Heart Rate; Male; Morphine; Naloxone; Rats | 1982 |
Opioids regulate cell proliferation in the developing rat uterus: effects during the period of sexual maturation.
Topics: Aging; Analysis of Variance; Animals; Cell Division; Cell Nucleus; DNA; Enkephalin, Methionine; Estradiol; Female; Kinetics; Naloxone; Ovariectomy; Rats; Rats, Inbred Strains; Receptors, Estradiol; Receptors, Opioid; Sexual Maturation; Uterus | 1996 |
Opioid peptides inhibit the estradiol-induced proliferation of cultured rat uterine cells.
Topics: Age Factors; Animals; Cell Division; Cells, Cultured; Enkephalin, Methionine; Estradiol; Estrogen Antagonists; Female; Naloxone; Narcotic Antagonists; Rats; Uterus | 1997 |
Opioid peptides inhibit the action of oestradiol on human myometrial cells in culture.
Topics: Adult; Cell Division; Cells, Cultured; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Methionine; Enkephalins; Estradiol; Female; Humans; Inhibitory Concentration 50; Muscle, Smooth; Myometrium; Naloxone; Narcotic Antagonists; Progesterone | 1999 |
Epidermal growth factor influenced by opioid peptides in immature rat uterus.
Topics: Animals; DNA; Dose-Response Relationship, Drug; Drug Implants; Enkephalin, Methionine; Epidermal Growth Factor; Female; Kinetics; Naloxone; Narcotic Antagonists; Ovariectomy; Rats; Uterus | 2000 |
Effect of estradiol on expression and activation of Akt protein in rat hypothalamus exposed to chronic [D-Met2, Pro5]-enkephalinamide treatment.
Topics: Animals; Blotting, Western; Cell Nucleus; Drug Implants; Enkephalin, Methionine; Estradiol; Estrogen Receptor alpha; Estrogen Receptor beta; Female; Hypothalamus; Kinetics; Naloxone; Narcotic Antagonists; Narcotics; Ovariectomy; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Inbred Strains; Receptors, Progesterone; Time Factors | 2004 |