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enkephalin, met(2)-pronh2(5)- and morphine

enkephalin, met(2)-pronh2(5)- has been researched along with morphine in 15 studies

Compound Research Comparison

Studies
(enkephalin, met(2)-pronh2(5)-)
Trials
(enkephalin, met(2)-pronh2(5)-)
Recent Studies (post-2010)
(enkephalin, met(2)-pronh2(5)-)
Studies
(morphine)
Trials
(morphine)
Recent Studies (post-2010) (morphine)
650144,2705,2008,695

Protein Interaction Comparison

ProteinTaxonomyenkephalin, met(2)-pronh2(5)- (IC50)morphine (IC50)
Delta-type opioid receptorMus musculus (house mouse)0.2939
Delta-type opioid receptorRattus norvegicus (Norway rat)0.2278
Kappa-type opioid receptorMus musculus (house mouse)0.0828
Mu-type opioid receptorRattus norvegicus (Norway rat)0.0385
Kappa-type opioid receptorRattus norvegicus (Norway rat)0.0545
Mu-type opioid receptorHomo sapiens (human)0.122
Delta-type opioid receptorHomo sapiens (human)0.1199
Kappa-type opioid receptorCavia porcellus (domestic guinea pig)0.9308
Kappa-type opioid receptorHomo sapiens (human)0.655
Mu-type opioid receptorMus musculus (house mouse)0.3305
Mu-type opioid receptorCavia porcellus (domestic guinea pig)0.202
Beta-2 adrenergic receptorCavia porcellus (domestic guinea pig)0.25

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-199010 (66.67)18.7374
1990's4 (26.67)18.2507
2000's0 (0.00)29.6817
2010's1 (6.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Arévalo, JC; Arsequell, G; Barreto-Valer, K; Calle, LP; Gonzalez-Nunez, V; Jiménez-Barbero, J; Marcelo, F; Rodríguez, RE; Rosa, M; Sánchez-Sánchez, J; Valencia, G1
Erdö, F; Máté, I; Polgár, K; Székely, JI1
Gáti, T; Székely, JI; Szombath, D; Till, M1
Gyires, K1
Endröczi, E; Hepp, J; Korányi, L; Walentin, S1
Fekete, MI; Kanyicska, B; Kiem, DT; Stark, E1
Gáti, T; Rábai, K; Székely, JI; Szombath, D; Till, M1
Sándor, P; Sato, A; Sato, Y; Swenson, RS1
Andrási, F; Horváth, K; Miglécz, E; Sineger, E; Székely, JI; Tarnawa, I1
Berzétei, IP; Csaba, G; Dobozy, O; Kurgyis, J; Rónai, AZ1
Gintzler, AR; Scalisi, JA1
Mess, B; Rúzsás, C1
Miglécz, E; Rónai, AZ; Székely, JI1
Danitz, B; Jaszlits, L; Kauthny, K; Kósa, E; Székely, JI; Tardos, L1
Nishiyama, N; Schwartz, JP; Taniwaki, T; Wilson, D1

Other Studies

15 other study(ies) available for enkephalin, met(2)-pronh2(5)- and morphine

ArticleYear
Role of the sugar moiety on the opioid receptor binding and conformation of a series of enkephalin neoglycopeptides.
    Bioorganic & medicinal chemistry, 2017, 04-01, Volume: 25, Issue:7

    Topics: Animals; Carbohydrates; Enkephalins; Glycopeptides; Glycosylation; Magnetic Resonance Spectroscopy; Male; Mice; Mice, Inbred C57BL; Protein Conformation; Receptors, Opioid; Structure-Activity Relationship

2017
Modulation of dopamine-induced hypermotility following injection of various opioids into the nucleus accumbens.
    Acta physiologica Hungarica, 1990, Volume: 76, Issue:3

    Topics: Animals; Chlorpromazine; Dopamine; Dopamine Antagonists; Enkephalin, Methionine; Enkephalins; Haloperidol; Male; Morphine; Motor Activity; Nucleus Accumbens; Rats; Receptors, Opioid; Receptors, Opioid, mu

1990
Naloxone-insensitive modulation of gastric acid output by [D-Met2,Pro5]enkephalinamide in rats.
    European journal of pharmacology, 1990, Jan-17, Volume: 175, Issue:3

    Topics: Animals; Enkephalin, Methionine; Gastric Acid; Male; Morphine; Naloxone; Pylorus; Rats; Rats, Inbred Strains; Stomach Ulcer

1990
The effect of different opiates on acidified ethanol-induced gastric lesions in rats.
    Acta physiologica Hungarica, 1990, Volume: 75 Suppl

    Topics: Animals; Benzomorphans; Enkephalin, Methionine; Ethanol; Morphine; Naloxone; Narcotics; Rats; Stomach Ulcer

1990
Changes of dipeptidyl peptidase (DP IV) activity in the T lymphocytes of rats following administration of ACTH, dexamethasone and opiates.
    Experimental and clinical endocrinology, 1989, Volume: 93, Issue:1

    Topics: Adrenocorticotropic Hormone; Animals; Dexamethasone; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Enkephalin, Methionine; Male; Morphine; Naloxone; Rats; Rats, Inbred Strains; Stress, Physiological; T-Lymphocytes

1989
Diurnal variation in prolactin, adrenocorticotropin and corticosterone release induced by opiate agonists in intact and adrenalectomized rats.
    Neuroendocrinology, 1987, Volume: 46, Issue:6

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adrenalectomy; Adrenocorticotropic Hormone; Analgesics; Animals; beta-Endorphin; Circadian Rhythm; Corticosterone; Dynorphins; Endorphins; Enkephalin, Methionine; Male; Morphine; Peptide Fragments; Prolactin; Pyrrolidines; Rats; Rats, Inbred Strains

1987
Effect of [D-Met2,Pro5]enkephalinamide on gastric ulceration and transmucosal potential difference.
    European journal of pharmacology, 1988, Jun-10, Volume: 150, Issue:3

    Topics: Analgesics; Animals; Cold Temperature; Enkephalin, Methionine; Evoked Potentials; Gastric Mucosa; Male; Morphine; Naloxone; Rats; Rats, Inbred Strains; Restraint, Physical; Stomach Ulcer; Stress, Psychological

1988
The effects of vertebral artery injections of an enkephalin analogue, (D-Met2,Pro5)-enkephalinamide, on somatosympathetic reflexes.
    Neuroscience letters, 1985, Jan-07, Volume: 53, Issue:1

    Topics: Analgesics; Animals; Blood-Brain Barrier; Cats; Central Nervous System; Enkephalin, Methionine; Injections, Intra-Arterial; Morphine; Nerve Fibers; Nerve Fibers, Myelinated; Reflex; Vertebral Artery

1985
Morphine and [D-Met2,Pro5]enkephalinamide do not show specific neuroleptic activity.
    European journal of pharmacology, 1982, Jun-04, Volume: 80, Issue:4

    Topics: Animals; Antipsychotic Agents; Apomorphine; Conditioning, Classical; Dose-Response Relationship, Drug; Endorphins; Enkephalin, Methionine; Enkephalins; Haloperidol; Humans; Male; Morphine; Motor Activity; Rats; Rats, Inbred Strains; Rotation; Stereotyped Behavior

1982
The effect of neonatal treatment of mice with opioid and dopaminergic agents on the late responsiveness of vasa deferentia to opioids in vitro.
    Acta biologica Hungarica, 1984, Volume: 35, Issue:1

    Topics: Animals; Animals, Newborn; Dopamine; Endorphins; Enkephalin, Methionine; Haloperidol; Male; Mice; Morphine; Naloxone; Piribedil; Sulpiride; Time Factors; Vas Deferens

1984
Physiological correlates of multiple subtypes of enteric opiate receptor; functional analysis of myenteric delta receptors.
    Brain research, 1982, Apr-22, Volume: 238, Issue:1

    Topics: Animals; Dose-Response Relationship, Drug; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Enkephalins; Guinea Pigs; Ileum; Morphine; Morphine Derivatives; Myenteric Plexus; Receptors, Opioid; Receptors, Opioid, delta

1982
Opioidergic regulation of thyroid activity: possible interference with the serotonergic system.
    Psychoneuroendocrinology, 1983, Volume: 8, Issue:1

    Topics: Animals; Depression, Chemical; Enkephalin, Methionine; Hypothalamus; Male; Morphine; Propylthiouracil; Rats; Receptors, Serotonin; Serotonin; Thyroid Gland; Thyroidectomy; Thyrotropin; Thyrotropin-Releasing Hormone

1983
Biphasic effects of a potent enkephalin analogue (D-Met2,Pro5)-enkephalinamide and morphine on locomotor activity in mice.
    Psychopharmacology, 1980, Volume: 71, Issue:3

    Topics: Animals; Dose-Response Relationship, Drug; Endorphins; Enkephalin, Methionine; Enkephalins; Male; Mice; Morphine; Motor Activity; Time Factors

1980
Cardiovascular effects of a potent opioid peptide, (D-Met2, Pro5)-enkephalinamide.
    Archives internationales de pharmacodynamie et de therapie, 1982, Volume: 260, Issue:1

    Topics: Anesthesia; Animals; Blood Pressure; Cats; Enkephalin, Methionine; Female; Heart Rate; Male; Morphine; Naloxone; Rats

1982
Receptor-mediated regulation of neuropeptide gene expression in astrocytes.
    Glia, 1994, Volume: 11, Issue:2

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Astrocytes; Benzomorphans; Brain; Enkephalin, Methionine; Etorphine; Gene Expression Regulation; Morphine; Naltrexone; Nerve Tissue Proteins; Neuropeptides; Organ Specificity; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Receptors, Opioid

1994