enkephalin, met(2)-pronh2(5)- and enkephalin, methionine

enkephalin, met(2)-pronh2(5)- has been researched along with enkephalin, methionine in 63 studies

Compound Research Comparison

Studies (enkephalin, met(2)-pronh2(5)-)	Trials (enkephalin, met(2)-pronh2(5)-)	Recent Studies (post-2010) (enkephalin, met(2)-pronh2(5)-)	Studies (enkephalin, methionine)	Trials (enkephalin, methionine)	Recent Studies (post-2010) (enkephalin, methionine)
65	0	1	4,439	45	225
65	0	1	23	0	8

Protein Interaction Comparison

Protein	Taxonomy	enkephalin, methionine (IC50)
Delta-type opioid receptor	Mus musculus (house mouse)	0.013
Delta-type opioid receptor	Rattus norvegicus (Norway rat)	0.129
Mu-type opioid receptor	Rattus norvegicus (Norway rat)	0.129
Kappa-type opioid receptor	Rattus norvegicus (Norway rat)	0.129
Mu-type opioid receptor	Homo sapiens (human)	0.013
Delta-type opioid receptor	Homo sapiens (human)	0.0064

Research

Studies (63)

Timeframe	Studies, this research(%)	All Research%
pre-1990	39 (61.90)	18.7374
1990's	19 (30.16)	18.2507
2000's	4 (6.35)	29.6817
2010's	1 (1.59)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Fedotova, TV; Lishmanov, IuB; Maslov, LN; Rebrova, TIu	1
Afanas'ev, SA; Kravchenko, AI; Lishmanov, IuB; Rebrova, TIu	1
Kovács, GL; Kriván, M; Sarnyai, Z; Szabó, G; Telegdy, G	1
Csernus, V; Gerendai, I; Nemeskéri, A	2
Barthó, L; Ernst, R; Faulstroh, K; Pethö, G; Pierau, FK; Sann, H	1
Ordög, T; Vértes, M; Vértes, Z	1
Barthó, L; Ernst, R; Pierau, FK; Sann, H	1
Halász, B; Molnár, J	1
Erdö, F; Máté, I; Polgár, K; Székely, JI	1
Gáti, T; Székely, JI; Szombath, D; Till, M	1
Gyires, K	1
Csányi, E; Erdö, F; Németh, Z; Török, K; Tory, K	1
Bartho, L; Vizi, ES	1
Endröczi, E; Hepp, J; Korányi, L; Walentin, S	1
Joffe, S; Murphy, RF; Sperling, MA; Werther, GA	1
Fekete, MI; Kanyicska, B; Kiem, DT; Stark, E	2
Hemal, AK; Sankaranarayanan, A; Szekely, JI; Vaidyanathan, S	1
Gamse, R; Saria, A	1
Decsi, L; Schmidt, P	1
Gogolak, I; Gotoh, F; Sándor, P; Tanahashi, N; Tomita, M	1
Karczag, I; Székely, JI; Till, M; Tolna, J; Török, K	1
Barthó, L	1
Gáti, T; Rábai, K; Székely, JI; Szombath, D; Till, M	1
Hartvig, P; Långström, B; Lärkfors, L; Lundberg, PO; Lundqvist, H; Muhr, C; Någren, K; Terenius, L	1
Amann, R; Barthó, L; Lembeck, F; Saria, A; Szolcsányi, J	1
De Leenheer, AP; Nelis, HJ	1
Sándor, P; Sato, A; Sato, Y; Swenson, RS	1
Arndt, JO; Inoue, K; Nashan, B	1
Bános, C; Földes, J; Gara, A; Székely, J; Török, K; Váradi, A; Varga, P	1
Costa, G; Ferri, S; Reina, RA; Scoto, GM; Spadaro, C; Spampinato, S	1
Bajusz, S; Berzétei, IP; Rónai, AZ; Székely, JI	1
Andrási, F; Horváth, K; Miglécz, E; Sineger, E; Székely, JI; Tarnawa, I	1
Barthó, L; Donnerer, J; Lembeck, F	1
Barthó, L; Holzer, P; Lembeck, F; Lippe, IT	1
Berzétei, IP; Csaba, G; Dobozy, O; Kurgyis, J; Rónai, AZ	1
Bajusz, S; Garbay-Jaureguiberry, C; Maigret, B; Roques, BP	1
Gintzler, AR; Scalisi, JA	1
Bondarenko, TT	1
Artal, R; Joffe, S; Sperling, MA; Werther, GA	1
Mess, B; Rúzsás, C	1
Halász, B; Nagy, G; Takács, L	1
Borvendég, J; Földes, J; Gara, A; Karczag, I; Marosfi, S; Rónai, AZ; Székely, JI; Tolna, J; Török, K; Váradi, A	1
Benedek, G; Székely, JI; Szikszay, M	1
Miglécz, E; Rónai, AZ; Székely, JI	1
Halász, B; Köves, K; Marton, J; Molnár, J	1
Kovács, S; Melegh, G; Vértes, M; Vértes, Z	1
Dhorajiwala, J; Ipp, E; Moossa, AR; Pugh, W; Rubenstein, AH	1
Danitz, B; Jaszlits, L; Kauthny, K; Kósa, E; Székely, JI; Tardos, L	1
Krieger, AJ; Sapru, HN; Willette, RN	1
Nishiyama, N; Schwartz, JP; Taniwaki, T; Wilson, D	1
Carr, JA; Saland, LC; Samora, A; Tejeda, D	1
Környei, JL; Kovács, S; Vértes, M; Vértes, Z	1
Lin, H; Reddy, IK; Shah, S; Yoburn, BC; Zito, SW	1
Környei, JL; Kovács, S; Oszter, A; Vértes, M; Vértes, Z	1
Környei, JL; Kovács, KA; Oszter, A; Rao, CV; Vértes, M; Vértes, Z	1
Környei, JL; Kovács, KA; Kovács, S; Oszter, A; Sándor, A; Vértes, M; Vértes, Z	1
Környei, JL; Kovács, KA; Oszter, A; Töröcsik, B; Vértes, M; Vértes, Z	1
Göcze, PM; Komlósi, KM; Környei, JL; Kovács, KA; Oszter, A; Vértes, M; Vértes, Z	1
Környei, JL; Lengyel, F; Oszter, A; Sumegi, B; Vértes, M; Vértes, Z	1
Arévalo, JC; Arsequell, G; Barreto-Valer, K; Calle, LP; Gonzalez-Nunez, V; Jiménez-Barbero, J; Marcelo, F; Rodríguez, RE; Rosa, M; Sánchez-Sánchez, J; Valencia, G	1

Other Studies

63 other study(ies) available for enkephalin, met(2)-pronh2(5)- and enkephalin, methionine

Article	Year
[The participation of prostanoids in the realization of the cardioprotective, antistressor and anti-arrhythmic effects of enkephalins]. Vestnik Rossiiskoi akademii meditsinskikh nauk, 1992, Issue:11-12 Topics: Animals; Anti-Arrhythmia Agents; Disease Models, Animal; Drug Evaluation, Preclinical; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Heart; Myocardial Ischemia; Myocardium; Prostaglandins; Stress, Physiological; Ventricular Fibrillation	1992
[The effect of synthetic enkephalins on prostaglandin synthesis and lipid peroxidation in the isolated heart during the activation of free-radical processes]. Biulleten' eksperimental'noi biologii i meditsiny, 1992, Volume: 114, Issue:11 Topics: Animals; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Enkephalins; Female; Free Radicals; Heart; In Vitro Techniques; Lipid Peroxidation; Myocardium; Prostaglandins; Rats; Thromboxanes	1992
Oxytocin blocks the development of heroin-enkephalin cross-tolerance in mice. Pharmacology, biochemistry, and behavior, 1992, Volume: 43, Issue:1 Topics: Analgesics; Animals; Dose-Response Relationship, Drug; Drug Tolerance; Enkephalin, Methionine; Enkephalins; Heroin; Injections, Intraventricular; Male; Mice; Mice, Inbred Strains; Nociceptors; Oxytocin; Pain Measurement; Reaction Time	1992
Vasectomy modulates the local effect of intratesticular opioids on the gonad of immature rats. Neuroendocrinology, 1992, Volume: 56, Issue:3 Topics: Animals; Enkephalin, Methionine; Injections; Male; Naloxone; Organ Size; Rats; Rats, Sprague-Dawley; Testis; Testosterone; Vasectomy	1992
An opioid peptide inhibits capsaicin-sensitive vasodilatation in the pig's skin. Neuropeptides, 1992, Volume: 23, Issue:4 Topics: Animals; Capsaicin; Electric Stimulation; Enkephalin, Methionine; Guanethidine; Microcirculation; Naloxone; Neurons; Skin; Swine; Tetrodotoxin; Vasodilation	1992
Inhibition of oestradiol-induced DNA synthesis by opioid peptides in the rat uterus. Life sciences, 1992, Volume: 51, Issue:15 Topics: Animals; DNA; Endorphins; Enkephalin, Methionine; Estradiol; Estrogen Antagonists; Female; Male; Naloxone; Ovariectomy; Rats; Rats, Inbred Strains; Uterus	1992
Endogenous opioids and ruthenium red inhibit the flare reaction in the pig skin by different mechanisms. Annals of the New York Academy of Sciences, 1991, Volume: 632 Topics: Animals; Capsaicin; Enkephalin, Methionine; Hypersensitivity, Immediate; Naloxone; Regional Blood Flow; Ruthenium Red; Skin; Skin Physiological Phenomena; Swine; Vasodilation	1991
Mesencephalic sites of action of an enkephalin analogue (D-Met2, Pro5)-enkephalinamide and naloxone on the anterior pituitary of male rats. Brain research, 1991, Nov-01, Volume: 563, Issue:1-2 Topics: Animals; Enkephalin, Methionine; In Vitro Techniques; Injections; Male; Mesencephalon; Naloxone; Pituitary Gland, Anterior; Pituitary Hormones, Anterior; Rats; Rats, Inbred Strains	1991
Modulation of dopamine-induced hypermotility following injection of various opioids into the nucleus accumbens. Acta physiologica Hungarica, 1990, Volume: 76, Issue:3 Topics: Animals; Chlorpromazine; Dopamine; Dopamine Antagonists; Enkephalin, Methionine; Enkephalins; Haloperidol; Male; Morphine; Motor Activity; Nucleus Accumbens; Rats; Receptors, Opioid; Receptors, Opioid, mu	1990
Intratesticular injection of [D-Met2-Pro5]enkephalinamide suppresses testosterone secretion of the testis of immature rat. Regulatory peptides, 1990, Volume: 27, Issue:1 Topics: Animals; Animals, Newborn; Enkephalin, Methionine; Female; In Vitro Techniques; Injections; Male; Naloxone; Orchiectomy; Pregnancy; Rats; Testis; Testosterone	1990
Naloxone-insensitive modulation of gastric acid output by [D-Met2,Pro5]enkephalinamide in rats. European journal of pharmacology, 1990, Jan-17, Volume: 175, Issue:3 Topics: Animals; Enkephalin, Methionine; Gastric Acid; Male; Morphine; Naloxone; Pylorus; Rats; Rats, Inbred Strains; Stomach Ulcer	1990
The effect of different opiates on acidified ethanol-induced gastric lesions in rats. Acta physiologica Hungarica, 1990, Volume: 75 Suppl Topics: Animals; Benzomorphans; Enkephalin, Methionine; Ethanol; Morphine; Naloxone; Narcotics; Rats; Stomach Ulcer	1990
Immunomodulatory activity of D-Met2-Pro5-enkephalinamide. Acta physiologica Hungarica, 1990, Volume: 75 Suppl Topics: Animals; Antibody Formation; Arthritis, Experimental; Enkephalin, Methionine; Hypersensitivity, Delayed; Immunity; Macrophages; Mice; Mice, Inbred CBA; Mitogens; Phagocytosis; Rats; Spleen	1990
Presynaptic modulation by noradrenaline and an opioid of the substance P-induced release of [3H]acetylcholine from the myenteric plexus. Regulatory peptides, 1985, Nov-28, Volume: 12, Issue:4 Topics: Acetylcholine; Animals; Dose-Response Relationship, Drug; Enkephalin, Methionine; Guinea Pigs; Myenteric Plexus; Norepinephrine; Substance P; Synapses; Time Factors	1985
Changes of dipeptidyl peptidase (DP IV) activity in the T lymphocytes of rats following administration of ACTH, dexamethasone and opiates. Experimental and clinical endocrinology, 1989, Volume: 93, Issue:1 Topics: Adrenocorticotropic Hormone; Animals; Dexamethasone; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Enkephalin, Methionine; Male; Morphine; Naloxone; Rats; Rats, Inbred Strains; Stress, Physiological; T-Lymphocytes	1989
The regulation of basal pancreatic polypeptide levels in dogs. Regulatory peptides, 1987, Volume: 17, Issue:4 Topics: Animals; Dogs; Enkephalin, Methionine; Female; Glucagon; Insulin; Naloxone; Pancreatic Polypeptide; Phentolamine; Propranolol; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Receptors, Opioid; Somatostatin	1987
Diurnal variation in prolactin, adrenocorticotropin and corticosterone release induced by opiate agonists in intact and adrenalectomized rats. Neuroendocrinology, 1987, Volume: 46, Issue:6 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adrenalectomy; Adrenocorticotropic Hormone; Analgesics; Animals; beta-Endorphin; Circadian Rhythm; Corticosterone; Dynorphins; Endorphins; Enkephalin, Methionine; Male; Morphine; Peptide Fragments; Prolactin; Pyrrolidines; Rats; Rats, Inbred Strains	1987
Prolactin release induced by opiate agonists, effect of glucocorticoid pretreatment in intact and adrenalectomized rats. Neuroendocrinology, 1988, Volume: 48, Issue:2 Topics: Adrenalectomy; Animals; beta-Endorphin; Cerebral Ventricles; Dynorphins; Endorphins; Enkephalin, Methionine; Hydrocortisone; Injections, Intraventricular; Male; Prolactin; Rats; Rats, Inbred Strains; Reference Values	1988
Lowering of maximum urethral pressure by (D-Met2, Pro5)-enkephalinamide in patients with neurogenic vesicourethral dysfunction due to spinal cord injury. International journal of clinical pharmacology, therapy, and toxicology, 1989, Volume: 27, Issue:2 Topics: Adult; Enkephalin, Methionine; Female; Heart Rate; Humans; Male; Paraplegia; Pressure; Spinal Cord Injuries; Urethra; Urinary Bladder, Neurogenic	1989
Antidromic vasodilatation in the rat hindpaw measured by laser Doppler flowmetry: pharmacological modulation. Journal of the autonomic nervous system, 1987, Volume: 19, Issue:2 Topics: Adrenergic Fibers; Animals; Capsaicin; Cimetidine; Electric Stimulation; Enkephalin, Methionine; Female; Fentanyl; Hindlimb; Lasers; Male; Naloxone; Pyrilamine; Rats; Regional Blood Flow; Rheology; Skin; Vasodilation	1987
Effect of (D-Met2, Pro5)enkephalinamide, a highly potent opiate agonist, on the drinking behaviour of rats. Neuropharmacology, 1985, Volume: 24, Issue:1 Topics: Angiotensin II; Animals; Dose-Response Relationship, Drug; Drinking Behavior; Drug Interactions; Enkephalin, Methionine; Female; Injections, Intraventricular; Isoproterenol; Male; Rats; Rats, Inbred Strains; Receptors, Opioid; Time Factors; Water Deprivation	1985
Effects of a stable enkephalin analogue, (D-Met2,Pro5)-enkephalinamide, and naloxone on cortical blood flow and cerebral blood volume in experimental brain ischemia in anesthetized cats. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1986, Volume: 6, Issue:5 Topics: Animals; Blood Volume; Brain; Brain Ischemia; Cats; Cerebral Cortex; Cerebrovascular Circulation; Enkephalin, Methionine; Female; Male; Naloxone; Receptors, Opioid; Vascular Resistance	1986
Effects of D-Met2, Pro5-enkephalinamide on pain tolerance and some cognitive functions in man. Psychopharmacology, 1986, Volume: 89, Issue:4 Topics: Adult; Attention; Codeine; Cognition; Enkephalin, Methionine; Humans; Male; Memory; Memory, Short-Term; Middle Aged; Pain; Sensory Thresholds	1986
Naloxone-precipitated contractions of the guinea pig ileum made tolerant to a synthetic opioid peptide: evidence against the involvement of capsaicin-sensitive neurones. Neuroscience letters, 1988, Dec-19, Volume: 95, Issue:1-3 Topics: Animals; Capsaicin; Enkephalin, Methionine; Female; Guinea Pigs; Ileum; Male; Muscle Contraction; Muscle, Smooth; Naloxone	1988
Effect of [D-Met2,Pro5]enkephalinamide on gastric ulceration and transmucosal potential difference. European journal of pharmacology, 1988, Jun-10, Volume: 150, Issue:3 Topics: Analgesics; Animals; Cold Temperature; Enkephalin, Methionine; Evoked Potentials; Gastric Mucosa; Male; Morphine; Naloxone; Rats; Rats, Inbred Strains; Restraint, Physical; Stomach Ulcer; Stress, Psychological	1988
Kinetics of four 11C-labelled enkephalin peptides in the brain, pituitary and plasma of rhesus monkeys. Regulatory peptides, 1986, Dec-01, Volume: 16, Issue:1 Topics: Animals; Biological Transport, Active; Brain; Enkephalin, Methionine; Enkephalins; Kinetics; Macaca mulatta; Pituitary Gland; Tomography, Emission-Computed	1986
Peripheral effects of opioid drugs on capsaicin-sensitive neurones of the guinea-pig bronchus and rabbit ear. Naunyn-Schmiedeberg's archives of pharmacology, 1987, Volume: 336, Issue:3 Topics: Acetylcholine; Animals; Atropine; Blood Pressure; Bronchi; Capsaicin; Ear, External; Enkephalin, Methionine; Female; Fentanyl; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Narcotics; Neurons; Pain; Rabbits	1987
Quality control of azure B preparations by liquid chromatography and standardization with azure B tetrafluoroborate. Clinica chimica acta; international journal of clinical chemistry, 1986, May-15, Volume: 156, Issue:3 Topics: Azure Stains; Calibration; Chromatography, High Pressure Liquid; Enkephalin, Methionine; Phenothiazines; Quality Control; Reference Standards; Solutions	1986
The effects of vertebral artery injections of an enkephalin analogue, (D-Met2,Pro5)-enkephalinamide, on somatosympathetic reflexes. Neuroscience letters, 1985, Jan-07, Volume: 53, Issue:1 Topics: Analgesics; Animals; Blood-Brain Barrier; Cats; Central Nervous System; Enkephalin, Methionine; Injections, Intra-Arterial; Morphine; Nerve Fibers; Nerve Fibers, Myelinated; Reflex; Vertebral Artery	1985
[D-Met2,Pro5]enkephalinamide activates cardioinhibitory efferents in anaesthetized dogs. European journal of pharmacology, 1985, Apr-02, Volume: 110, Issue:2 Topics: Action Potentials; Anesthesia; Animals; Blood Pressure; Carbon Dioxide; Dogs; Efferent Pathways; Enkephalin, Methionine; Female; Heart; Heart Rate; Male; Naloxone; Vagus Nerve	1985
[Effect of an enkephalin analog on the endocrine system in man]. Orvosi hetilap, 1985, May-12, Volume: 126, Issue:19 Topics: Adult; Enkephalin, Methionine; Growth Hormone; Humans; Male; Methysergide; Pituitary Gland; Prolactin; Serotonin Antagonists; Thyrotropin	1985
Increase of plasma ACTH in the rat following the administration of D-met2-pro5-enkephalinamide. Pharmacological research communications, 1980, Volume: 12, Issue:5 Topics: Adrenocorticotropic Hormone; Animals; Endorphins; Enkephalin, Methionine; Enkephalins; Injections, Intravenous; Male; Neurotransmitter Agents; Radioimmunoassay; Rats; Stimulation, Chemical	1980
The in vitro pharmacology of D-Met2,Pro5-enkephalinamide. The Journal of pharmacy and pharmacology, 1981, Volume: 33, Issue:8 Topics: Animals; Endorphins; Enkephalin, Methionine; Enkephalins; In Vitro Techniques; Kinetics; Male; Muscle Contraction; Muscle, Smooth; Naltrexone; Narcotics; Nictitating Membrane; Rats; Receptors, Opioid; Vas Deferens	1981
Morphine and [D-Met2,Pro5]enkephalinamide do not show specific neuroleptic activity. European journal of pharmacology, 1982, Jun-04, Volume: 80, Issue:4 Topics: Animals; Antipsychotic Agents; Apomorphine; Conditioning, Classical; Dose-Response Relationship, Drug; Endorphins; Enkephalin, Methionine; Enkephalins; Haloperidol; Humans; Male; Morphine; Motor Activity; Rats; Rats, Inbred Strains; Rotation; Stereotyped Behavior	1982
Inhibition of neurogenic vasodilation and plasma extravasation by substance P antagonists, somatostatin and [D-Met2, Pro5]enkephalinamide. European journal of pharmacology, 1982, Nov-19, Volume: 85, Issue:2 Topics: Animals; Enkephalin, Methionine; Female; Male; Peripheral Nerves; Plasma; Rats; Somatostatin; Substance P; Vasodilation	1982
[D-Met2, Pro5]enkephalinamide and dynorphin-(1-13) inhibit the cholinergic contraction induced in the guinea-pig ileum by substance P. European journal of pharmacology, 1983, Jul-15, Volume: 91, Issue:1 Topics: Animals; Atropine; Dynorphins; Endorphins; Enkephalin, Methionine; Female; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Naloxone; Parasympathetic Nervous System; Peptide Fragments; Substance P	1983
The effect of neonatal treatment of mice with opioid and dopaminergic agents on the late responsiveness of vasa deferentia to opioids in vitro. Acta biologica Hungarica, 1984, Volume: 35, Issue:1 Topics: Animals; Animals, Newborn; Dopamine; Endorphins; Enkephalin, Methionine; Haloperidol; Male; Mice; Morphine; Naloxone; Piribedil; Sulpiride; Time Factors; Vas Deferens	1984
Studies of the conformational behaviour and preferential interactions with opiate receptors of the cis and trans forms of [Dmet2,pro5]enkephalin and [Dmet2,pro5]enkephalinamide by 1H and 13C NMR, theoretical calculations and 13C relaxation measurements. European journal of biochemistry, 1980, Volume: 113, Issue:1 Topics: Carbon Isotopes; Endorphins; Enkephalin, Methionine; Enkephalins; Hydrogen; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Protein Conformation; Receptors, Opioid; Stereoisomerism	1980
Physiological correlates of multiple subtypes of enteric opiate receptor; functional analysis of myenteric delta receptors. Brain research, 1982, Apr-22, Volume: 238, Issue:1 Topics: Animals; Dose-Response Relationship, Drug; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Enkephalins; Guinea Pigs; Ileum; Morphine; Morphine Derivatives; Myenteric Plexus; Receptors, Opioid; Receptors, Opioid, delta	1982
[Effect of enkephalinamide on the sensitivity of neurons of the lateral hypothalamus to phenamine in the rat]. Neirofiziologiia = Neurophysiology, 1984, Volume: 16, Issue:2 Topics: Action Potentials; Amphetamine; Animals; Drug Interactions; Enkephalin, Methionine; Hypothalamic Area, Lateral; Male; Nalorphine; Rats; Rats, Inbred Strains; Receptors, Opioid	1984
Opiates modulate insulin action in vivo in dogs. Diabetologia, 1984, Volume: 26, Issue:1 Topics: Animals; Blood Glucose; Dogs; Enkephalin, Methionine; Epinephrine; Female; Glucagon; Hydrocortisone; Insulin; Naloxone	1984
Opioidergic regulation of thyroid activity: possible interference with the serotonergic system. Psychoneuroendocrinology, 1983, Volume: 8, Issue:1 Topics: Animals; Depression, Chemical; Enkephalin, Methionine; Hypothalamus; Male; Morphine; Propylthiouracil; Rats; Receptors, Serotonin; Serotonin; Thyroid Gland; Thyroidectomy; Thyrotropin; Thyrotropin-Releasing Hormone	1983
(D-Met2,Pro5) enkephalinamide causes a decrease in plasma prolactin levels of lactating rats continuously suckled and an increase in those deprived of their litter. Regulatory peptides, 1984, Volume: 8, Issue:4 Topics: Animals; Enkephalin, Methionine; Female; Kinetics; Lactation; Naloxone; Pregnancy; Prolactin; Rats; Rats, Inbred Strains	1984
Human tolerability studies with D-Met2,Pro5-enkephalinamide. Life sciences, 1983, Volume: 33 Suppl 1 Topics: Adult; Blood Pressure; Enkephalin, Methionine; Growth Hormone; Humans; Injections, Subcutaneous; Male; Middle Aged; Prolactin; Pulse; Respiration	1983
Thermoregulatory effects of D-met2-pro5-enkephalinamide. Neuropeptides, 1983, Volume: 3, Issue:6 Topics: Animals; Body Temperature Regulation; Capsaicin; Drug Antagonism; Drug Synergism; Enkephalin, Methionine; Humans; Male; Naloxone; Rats; Rats, Inbred Strains; Restraint, Physical; Stress, Psychological	1983
Biphasic effects of a potent enkephalin analogue (D-Met2,Pro5)-enkephalinamide and morphine on locomotor activity in mice. Psychopharmacology, 1980, Volume: 71, Issue:3 Topics: Animals; Dose-Response Relationship, Drug; Endorphins; Enkephalin, Methionine; Enkephalins; Male; Mice; Morphine; Motor Activity; Time Factors	1980
(D-Met2,Pro5)-enkephalinamide-induced blockade of ovulation and its reversal by naloxone in the rat. Neuroendocrinology, 1981, Volume: 32, Issue:2 Topics: Animals; Dose-Response Relationship, Drug; Endorphins; Enkephalin, Methionine; Enkephalins; Estrus; Female; Follicle Stimulating Hormone; Luteinizing Hormone; Naloxone; Ovulation; Pregnancy; Rats	1981
Effect of naloxone and D-met2-pro5-enkephalinamide treatment on the DNA synthesis in the developing rat brain. Life sciences, 1982, Jul-12, Volume: 31, Issue:2 Topics: Animals; Brain; Cerebellum; DNA; Enkephalin, Methionine; Female; Hypothalamus; Naloxone; Rats; Time Factors	1982
Effects of an enkephalin analog on pancreatic endocrine function and glucose homeostasis in normal and diabetic dogs. Endocrinology, 1982, Volume: 111, Issue:6 Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Dogs; Dose-Response Relationship, Drug; Enkephalin, Methionine; Gastric Mucosa; Glucagon; Homeostasis; Naloxone; Pancreas	1982
Factors and mechanisms influencing bone growth. Proceedings of the International Conference, University of California Center for the Health Sciences, Los Angeles, California, January 5-7, 1982. Progress in clinical and biological research, 1982, Volume: 101 Topics: Animals; Bone and Bones; Bone Development; Enkephalin, Methionine	1982
Cardiovascular effects of a potent opioid peptide, (D-Met2, Pro5)-enkephalinamide. Archives internationales de pharmacodynamie et de therapie, 1982, Volume: 260, Issue:1 Topics: Anesthesia; Animals; Blood Pressure; Cats; Enkephalin, Methionine; Female; Heart Rate; Male; Morphine; Naloxone; Rats	1982
Stimulation of pulmonary J receptors by an enkephalin-analog. The Journal of pharmacology and experimental therapeutics, 1981, Volume: 217, Issue:1 Topics: Animals; Blood Pressure; Endorphins; Enkephalin, Methionine; Enkephalins; Male; Phrenic Nerve; Pulmonary Artery; Rats; Respiration; Sensory Receptor Cells; Stimulation, Chemical	1981
Receptor-mediated regulation of neuropeptide gene expression in astrocytes. Glia, 1994, Volume: 11, Issue:2 Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Astrocytes; Benzomorphans; Brain; Enkephalin, Methionine; Etorphine; Gene Expression Regulation; Morphine; Naltrexone; Nerve Tissue Proteins; Neuropeptides; Organ Specificity; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Receptors, Opioid	1994
Effects of the enkephalin analog (D-Met2,Pro5)-enkephalinamide on alpha-melanocyte-stimulating hormone secretion. Regulatory peptides, 1993, Sep-03, Volume: 47, Issue:2 Topics: alpha-MSH; Animals; Dose-Response Relationship, Drug; Enkephalin, Methionine; Male; Naltrexone; Pituitary Gland; Rats; Rats, Sprague-Dawley; Time Factors	1993
Opioids regulate cell proliferation in the developing rat uterus: effects during the period of sexual maturation. The Journal of steroid biochemistry and molecular biology, 1996, Volume: 59, Issue:2 Topics: Aging; Analysis of Variance; Animals; Cell Division; Cell Nucleus; DNA; Enkephalin, Methionine; Estradiol; Female; Kinetics; Naloxone; Ovariectomy; Rats; Rats, Inbred Strains; Receptors, Estradiol; Receptors, Opioid; Sexual Maturation; Uterus	1996
Synthesis and antinociceptive activity of [D-Met2, Pro5] enkephalin [N1,5-beta-D-2,3,4,6-O-tetraacetylglycosyl]--amide and [D-Met2, Pro5] enkephalinamide. Drug design and discovery, 1997, Volume: 15, Issue:2 Topics: Analgesics; Animals; Cornea; Drug Stability; Enkephalin, Methionine; Male; Mice; Pain Threshold; Rabbits; Receptors, Opioid, delta; Receptors, Opioid, mu	1997
Opioid peptides inhibit the estradiol-induced proliferation of cultured rat uterine cells. European journal of pharmacology, 1997, Oct-01, Volume: 336, Issue:1 Topics: Age Factors; Animals; Cell Division; Cells, Cultured; Enkephalin, Methionine; Estradiol; Estrogen Antagonists; Female; Naloxone; Narcotic Antagonists; Rats; Uterus	1997
Opioid peptides inhibit the action of oestradiol on human myometrial cells in culture. Molecular human reproduction, 1999, Volume: 5, Issue:6 Topics: Adult; Cell Division; Cells, Cultured; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Methionine; Enkephalins; Estradiol; Female; Humans; Inhibitory Concentration 50; Muscle, Smooth; Myometrium; Naloxone; Narcotic Antagonists; Progesterone	1999
Epidermal growth factor influenced by opioid peptides in immature rat uterus. Journal of endocrinological investigation, 2000, Volume: 23, Issue:8 Topics: Animals; DNA; Dose-Response Relationship, Drug; Drug Implants; Enkephalin, Methionine; Epidermal Growth Factor; Female; Kinetics; Naloxone; Narcotic Antagonists; Ovariectomy; Rats; Uterus	2000
Antiestrogenic effect of opioid peptides in rat uterus. The Journal of steroid biochemistry and molecular biology, 2000, Volume: 74, Issue:1-2 Topics: Animals; DNA; Enkephalin, Methionine; Estradiol; Estrogen Receptor Modulators; Female; Opioid Peptides; Ovariectomy; Protein Binding; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Rats; Rats, Inbred Strains; Receptors, Estrogen; Receptors, Progesterone; Transcription Factor AP-1; Uterus	2000
Anti-mitogenic action of opioid peptides on epidermal growth factor-stimulated uterine cells. European journal of pharmacology, 2001, Mar-02, Volume: 414, Issue:2-3 Topics: Analgesics; Animals; Cell Division; Cells, Cultured; Dose-Response Relationship, Drug; Enkephalin, Methionine; Epidermal Growth Factor; Female; Humans; Myometrium; Opioid Peptides; Rats; Receptors, Opioid; Uterus	2001
Effect of estradiol on expression and activation of Akt protein in rat hypothalamus exposed to chronic [D-Met2, Pro5]-enkephalinamide treatment. Steroids, 2004, Volume: 69, Issue:4 Topics: Animals; Blotting, Western; Cell Nucleus; Drug Implants; Enkephalin, Methionine; Estradiol; Estrogen Receptor alpha; Estrogen Receptor beta; Female; Hypothalamus; Kinetics; Naloxone; Narcotic Antagonists; Narcotics; Ovariectomy; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Inbred Strains; Receptors, Progesterone; Time Factors	2004
Role of the sugar moiety on the opioid receptor binding and conformation of a series of enkephalin neoglycopeptides. Bioorganic & medicinal chemistry, 2017, 04-01, Volume: 25, Issue:7 Topics: Animals; Carbohydrates; Enkephalins; Glycopeptides; Glycosylation; Magnetic Resonance Spectroscopy; Male; Mice; Mice, Inbred C57BL; Protein Conformation; Receptors, Opioid; Structure-Activity Relationship	2017