enkephalin, leucine and tiopronin

enkephalin, leucine has been researched along with tiopronin in 43 studies

Research

Studies (43)

TimeframeStudies, this research(%)All Research%
pre-199043 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kehl, LJ1
Livett, BG; Marley, PD; Mitchelhill, KI1
Dzoljic, MR; Haffmans, J; van Amsterdam, JC; Walsum, MV1
Cadden, S; Chitour, D; Le Bars, D; Villanueva, L1
Roques, BP1
Kalivas, PW; Richardson-Carlson, R1
Ernst, M; Roby, A; Willer, JC1
Buéno, L; Fioramonti, J1
Giros, B; Gros, C; Llorens-Cortes, C; Schwartz, JC1
Costentin, J; Giros, B; Michael-Titus, A; Preterre, P1
Martinez, JL; Walker, RC; Weinberger, SB; Zafuto, CE1
Gros, C; Llorens-Cortes, C; Schwartz, JC2
Kameyama, T; Katoh, A; Nabeshima, T1
Dickenson, AH; Fournie-Zaluski, MC; Roques, BP; Sullivan, AF1
Costentin, J; Danvy, D; Duhamel, L; Duhamel, P; Giros, B; Gros, C; Lecomte, JM; Plaquevent, JC; Schwartz, JC; Vlaiculescu, A1
Bouboutou, R; Bourgoin, S; Cesselin, F; Devin, J; Fournie-Zaluski, MC; Hamon, M; Roques, B; Waksman, G1
Han, JS; Yuan, H1
Frederickson, RC; Johnson, BG; Mendelsohn, LG; Scott, WL1
Deschodt-Lanckman, M1
Han, JS; Jin, WQ; Zhou, ZF1
Chaillet, P; Costentin, J; Coulaud, A; Fournie-Zaluski, MC; Roques, BP; Zajac, JM1
Aoki, K; Kajiwara, M; Oka, T1
Cohen, ML; Geary, LE; Scott, WL; Wiley, KS1
Chaillet, P; Costentin, J; Coulaud, A; Fournié-Zaluski, MC; Gacel, G; Roques, BP1
Brandt, U; Lentzen, H; Palenker, J1
Amano, H; Kaneko, S; Morimoto, Y; Takagi, H1
Lentzen, H; Palenker, J1
Chaillet, P; Costentin, J; de la Baume, S; Marcais-Collado, H; Schwartz, JC; Yi, CC2
Carenzi, A; Della Bella, D; Frigeni, V; Reggiani, A1
Bouboutou, R; Chaillet, P; Cherot, P; Costentin, J; Coulaud, A; Fournie-Zaluski, MC; Roques, BP; Waksman, G1
Soudijn, W; van Amsterdam, JG; van Buuren, KJ1
Chaillet, P; Costentin, J; Lecomte, JM; Marçais, H; Natan, LB; Uchida, G1
de Groat, WC; Hisamitsu, T1
Llorens-Cortes, C; Schwartz, JC1
Costa, E; Yang, HY; Zhang, AZ1
Barnett, A; Berger, J; Billard, W; Chipkin, RE; Iorio, LC1
Wood, PL1
Fournié-Zaluski, MC; Lecomte, JM; Llorens, C; Malfroy, B; Roques, BP; Schwartz, JC; Soroca, E1
De La Baume, S; Fournie-Zaluski, MC; Gros, C; Patey, G; Roques, B; Schwartz, JC; Soroca-Lucas, E1
Harty, GJ; Yaksh, TL1
Fulcher, IS; Kenny, AJ; Matsas, R; Turner, AJ1

Reviews

2 review(s) available for enkephalin, leucine and tiopronin

ArticleYear
[Enkephalinase inhibitors and molecular study of the differences between active sites of enkephalinase and angiotensin-converting enzyme].
    Journal de pharmacologie, 1985, Volume: 16 Suppl 1

    Topics: Analgesics; Animals; Binding Sites; Drug Synergism; Endopeptidases; Enkephalins; Humans; Metalloendopeptidases; Neprilysin; Peptidyl-Dipeptidase A; Protease Inhibitors; Sulfhydryl Compounds; Thiorphan; Tiopronin

1985
Enkephalins, other endogenous opioids and colonic motility in dog and man.
    Gastroenterologie clinique et biologique, 1987, Volume: 11, Issue:3 Pt 2

    Topics: Animals; Central Nervous System; Colon; Dogs; Endorphins; Enkephalins; Gastrointestinal Motility; Humans; In Vitro Techniques; Morphine; Muscle Contraction; Naloxone; Receptors, Opioid; Species Specificity; Thiorphan; Tiopronin

1987

Other Studies

41 other study(ies) available for enkephalin, leucine and tiopronin

ArticleYear
Analgesia after inhibition of enkephalin degradation.
    Journal of the American Dental Association (1939), 1986, Volume: 112, Issue:2

    Topics: Amino Acids, Sulfur; Analgesia; Animals; Enkephalins; Injections, Spinal; Male; Mice; Mice, Inbred Strains; Naloxone; Neprilysin; Protease Inhibitors; Spinal Cord; Substance P; Thiorphan; Tiopronin

1986
Effects of opioid peptides containing the sequence of Met5-enkephalin or Leu5-enkephalin on nicotine-induced secretion from bovine adrenal chromaffin cells.
    Journal of neurochemistry, 1986, Volume: 46, Issue:1

    Topics: Adenosine Triphosphate; Adrenal Medulla; Amino Acid Sequence; Animals; Bacitracin; Cattle; Dynorphins; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Epinephrine; Guinea Pigs; Leucine; Nicotine; Norepinephrine; Peptide Fragments; Phenanthrolines; Rabbits; Receptors, Opioid; Thiorphan; Tiopronin

1986
Phelorphan, an inhibitor of enzymes involved in the biodegradation of enkephalins, affected the withdrawal symptoms in chronic morphine-dependent rats.
    Neuroscience, 1987, Volume: 22, Issue:1

    Topics: Aminopeptidases; Animals; Brain; CD13 Antigens; Dipeptides; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Endopeptidases; Enkephalins; Male; Morphine Dependence; Naloxone; Neprilysin; Protease Inhibitors; Rats; Rats, Inbred Strains; Receptors, Opioid; Substance Withdrawal Syndrome; Thiorphan; Tiopronin

1987
Failure of ES 52, a highly potent enkephalinase inhibitor, to affect nociceptive transmission by rat dorsal horn convergent neurones.
    Brain research, 1985, Apr-29, Volume: 333, Issue:1

    Topics: Amino Acids, Sulfur; Animals; Enkephalins; Male; Nociceptors; Pain; Rats; Spinal Cord; Synaptic Transmission; Thiorphan; Tiopronin

1985
Endogenous enkephalin modulation of dopamine neurons in ventral tegmental area.
    The American journal of physiology, 1986, Volume: 251, Issue:2 Pt 2

    Topics: Animals; Behavior, Animal; Dopamine; Enkephalins; Male; Neurons; Rats; Rats, Inbred Strains; Receptors, Opioid; Tegmentum Mesencephali; Thiorphan; Tiopronin

1986
The enkephalinase inhibitor, GB 52, does not affect nociceptive flexion reflexes nor pain sensation in humans.
    Neuropharmacology, 1986, Volume: 25, Issue:8

    Topics: Adult; Amino Acids, Sulfur; Electric Stimulation; Endopeptidases; Enkephalins; Female; Humans; Male; Middle Aged; Neprilysin; Pain; Protease Inhibitors; Recruitment, Neurophysiological; Reflex; Spinal Cord; Sural Nerve; Synaptic Transmission; Thiorphan; Tiopronin

1986
[Opioid peptides: metabolism and receptors].
    Gastroenterologie clinique et biologique, 1987, Volume: 11, Issue:3 Pt 2

    Topics: Animals; Brain; Cattle; Endopeptidases; Endorphins; Enkephalins; Humans; Leucine; Mice; Neprilysin; Pro-Opiomelanocortin; Protease Inhibitors; Protein Precursors; Receptors, Opioid; Thiorphan; Tiopronin

1987
Role of endogenous enkephalins in locomotion evidenced by acetorphan, an "enkephalinase" inhibitor.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 243, Issue:3

    Topics: Amino Acids, Sulfur; Animals; Dose-Response Relationship, Drug; Enkephalins; Hydroxydopamines; Male; Metalloendopeptidases; Mice; Motor Activity; Naloxone; Neprilysin; Oxidopamine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Thiorphan; Tiopronin

1987
Characterization of enkephalin degradation in rat plasma.
    NIDA research monograph, 1986, Volume: 75

    Topics: Aminopeptidases; Animals; Anti-Bacterial Agents; Captopril; Enkephalin, Leucine; Enkephalins; Kinetics; Leucine; Male; Rats; Rats, Inbred Strains; Thiorphan; Tiopronin

1986
Evaluation of striatal enkephalin release in vivo from steady state levels and turnover rates of the tripeptide Tyr-Gly-Gly.
    NIDA research monograph, 1986, Volume: 75

    Topics: Animals; Anti-Bacterial Agents; Corpus Striatum; Enkephalins; In Vitro Techniques; Kinetics; Leucine; Male; Mice; Oligopeptides; Pentobarbital; Thiorphan; Tiopronin

1986
Inhibition of enkephalin degradation attenuated stress-induced motor suppression (conditioned suppression of motility).
    The Journal of pharmacology and experimental therapeutics, 1988, Volume: 244, Issue:1

    Topics: Amino Acids, Sulfur; Aminopeptidases; Animals; Corpus Striatum; Dopamine; Enkephalin, Methionine; Enkephalins; Leucine; Male; Metalloendopeptidases; Mice; Motor Activity; Naloxone; Neprilysin; Pimozide; Stress, Physiological; Thiorphan; Tiopronin

1988
Prevention of degradation of endogenous enkephalins produces inhibition of nociceptive neurones in rat spinal cord.
    Brain research, 1987, Apr-07, Volume: 408, Issue:1-2

    Topics: Action Potentials; Animals; Dipeptides; Enkephalins; Leucine; Male; Naloxone; Nerve Fibers; Neural Inhibition; Neurons, Afferent; Pain; Protease Inhibitors; Rats; Rats, Inbred Strains; Spinal Cord; Thiorphan; Tiopronin

1987
Enantiomers of thiorphan and acetorphan: correlation between enkephalinase inhibition, protection of endogenous enkephalins and behavioral effects.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 243, Issue:2

    Topics: Amino Acids, Sulfur; Analgesia; Angiotensin-Converting Enzyme Inhibitors; Animals; Corpus Striatum; Enkephalins; Globus Pallidus; In Vitro Techniques; Male; Metalloendopeptidases; Mice; Motor Activity; Neprilysin; Rats; Rats, Inbred Strains; Stereoisomerism; Thermolysin; Thiorphan; Tiopronin

1987
In vitro and in vivo effects of kelatorphan on enkephalin metabolism in rodent brain.
    European journal of pharmacology, 1985, Nov-05, Volume: 117, Issue:2

    Topics: Aminopeptidases; Animals; Brain; Brain Chemistry; Corpus Striatum; Dipeptides; Enkephalin, Methionine; Enkephalins; Hydrolysis; In Vitro Techniques; Leucine; Mice; Protease Inhibitors; Rats; Thiorphan; Tiopronin

1985
[Electroacupuncture accelerates the biogenesis of central enkephalins in the rat].
    Sheng li xue bao : [Acta physiologica Sinica], 1985, Volume: 37, Issue:3

    Topics: Acupuncture Therapy; Aminopeptidases; Animals; Brain; Electric Stimulation Therapy; Enkephalin, Leucine; Enkephalin, Methionine; Female; Leucine; Male; Phenylalanine; Radioimmunoassay; Rats; Thiorphan; Tiopronin; Transcutaneous Electric Nerve Stimulation

1985
Thiorphan and analogs: lack of correlation between potency to inhibit "enkephalinase A" in vitro and analgesic potency in vivo.
    The Journal of pharmacology and experimental therapeutics, 1985, Volume: 234, Issue:2

    Topics: Amino Acids, Sulfur; Analgesics; Animals; Enkephalins; In Vitro Techniques; Male; Mice; Neprilysin; Protease Inhibitors; Rats; Rats, Inbred Strains; Stereoisomerism; Thiorphan; Tiopronin

1985
[Enkephalinase, an enzyme in the catabolism of neuropeptides and circulating hormones].
    Revue medicale de Bruxelles, 1985, Volume: 6, Issue:6

    Topics: Brain; Endopeptidases; Enkephalins; Humans; Kidney; Neprilysin; Nerve Tissue Proteins; Thiorphan; Tiopronin

1985
Study of endogenous Tyr-Gly-Gly, a putative enkephalin metabolite, in mouse brain: validation of a radioimmunoassay, localisation and effects of peptidase inhibitors.
    European journal of pharmacology, 1985, Dec-17, Volume: 119, Issue:3

    Topics: Animals; Brain; Captopril; Chromatography, High Pressure Liquid; Enkephalin, Leucine; Enkephalin, Methionine; Leucine; Male; Mice; Microwaves; Nalorphine; Neprilysin; Oligopeptides; Protease Inhibitors; Radioimmunoassay; Thiorphan; Tiopronin

1985
[Inhibition of enkephalins degradation in the nucleus accumbens leads to potentiation of acupuncture and morphine analgesia].
    Sheng li xue bao : [Acta physiologica Sinica], 1985, Volume: 37, Issue:4

    Topics: Acupuncture Therapy; Aminopeptidases; Analgesia; Animals; Electric Stimulation Therapy; Endopeptidases; Enkephalin, Leucine; Enkephalin, Methionine; Leucine; Male; Morphine; Neprilysin; Nucleus Accumbens; Protease Inhibitors; Rabbits; Septal Nuclei; Thiorphan; Tiopronin; Transcutaneous Electric Nerve Stimulation

1985
The mu rather than the delta subtype of opioid receptors appears to be involved in enkephalin-induced analgesia.
    European journal of pharmacology, 1984, May-18, Volume: 101, Issue:1-2

    Topics: Analgesics; Animals; Enkephalin, Leucine; Enkephalins; Guinea Pigs; In Vitro Techniques; Leucine; Male; Mice; Morphine; Muscle Contraction; Muscle, Smooth; Nalorphine; Naloxone; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Thiorphan; Tiopronin

1984
The role of bestatin-sensitive aminopeptidase, angiotensin converting enzyme and thiorphan-sensitive "enkephalinase" in the potency of enkephalins in the guinea-pig ileum.
    Japanese journal of pharmacology, 1984, Volume: 36, Issue:1

    Topics: Amino Acids, Sulfur; Aminopeptidases; Animals; Anti-Bacterial Agents; Captopril; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Endopeptidases; Enkephalins; Guinea Pigs; Ileum; In Vitro Techniques; Leucine; Male; Neprilysin; Oligopeptides; Peptides; Peptidyl-Dipeptidase A; Thiorphan; Tiopronin

1984
Degradation of exogenous enkephalin in the guinea-pig ileum: relative importance of aminopeptidase, enkephalinase and angiotensin converting enzyme activity.
    The Journal of pharmacology and experimental therapeutics, 1982, Volume: 221, Issue:1

    Topics: Aminopeptidases; Angiotensin I; Animals; Bradykinin; Endopeptidases; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Neprilysin; Peptidyl-Dipeptidase A; Thiorphan; Tiopronin

1982
Pain control by endogenous enkephalins is mediated by mu opioid receptors.
    Life sciences, 1983, Volume: 33 Suppl 1

    Topics: Amino Acids, Sulfur; Analgesia; Animals; Enkephalin, Methionine; Enkephalins; Leucine; Male; Mice; Pain; Protease Inhibitors; Receptors, Opioid; Receptors, Opioid, mu; Thiorphan; Tiopronin

1983
Enkephalin degradation by enkephalinergic neuroblastoma cells. Involvement of angiotensin-converting-enzyme.
    Naunyn-Schmiedeberg's archives of pharmacology, 1984, Volume: 325, Issue:3

    Topics: Aminopeptidases; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Cell Line; Cell Membrane; Cells, Cultured; Enkephalin, Leucine; Hydrolysis; Leucine; Mice; Neuroblastoma; Peptidyl-Dipeptidase A; Thiorphan; Tiopronin

1984
Opioid activity of enkephalin analogues containing the kyotorphin-related structure in the N-terminus.
    Neuropharmacology, 1984, Volume: 23, Issue:4

    Topics: Analgesics; Animals; Brain; Cell Membrane; Endorphins; Enkephalins; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Protease Inhibitors; Rats; Rats, Inbred Strains; Receptors, Opioid; Thiorphan; Tiopronin; Vas Deferens

1984
Localization of the thiorphan-sensitive endopeptidase, termed enkephalinase A, on glial cells.
    FEBS letters, 1983, Mar-07, Volume: 153, Issue:1

    Topics: Aminopeptidases; Animals; Astrocytes; Brain; Cell Membrane; Cells, Cultured; Endopeptidases; Enkephalin, Leucine; Kinetics; Leucine; Neprilysin; Protease Inhibitors; Rats; Thiorphan; Tiopronin

1983
Peptidases involved in the inactivation of exogenous and endogenous enkephalins.
    Journal of neural transmission. Supplementum, 1983, Volume: 18

    Topics: Aminopeptidases; Animals; Brain; Endopeptidases; Enkephalins; Leucine; Mice; Neprilysin; Nociceptors; Rats; Thiorphan; Tiopronin

1983
Effect of inhibition of neuropeptidases on the pain threshold of mice and rats.
    Neuropharmacology, 1983, Volume: 22, Issue:11

    Topics: Aminopeptidases; Animals; Endopeptidases; Enkephalin, Leucine; Leucine; Male; Mice; Neprilysin; Pain; Protease Inhibitors; Rats; Rats, Inbred Strains; Sensory Thresholds; Species Specificity; Thiorphan; Tiopronin

1983
Analgesic effects of kelatorphan, a new highly potent inhibitor of multiple enkephalin degrading enzymes.
    European journal of pharmacology, 1984, Jul-20, Volume: 102, Issue:3-4

    Topics: Aminopeptidases; Analgesics; Animals; Brain; Dipeptides; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Endopeptidases; Enkephalin, Methionine; Enkephalins; In Vitro Techniques; Kidney; Leucine; Neprilysin; Protease Inhibitors; Rabbits; Rats; Reaction Time; Thiorphan; Tiopronin

1984
Inhibition of enkephalin metabolism by, and antinociceptive activity of, bestatin, an aminopeptidase inhibitor.
    European journal of pharmacology, 1983, Jan-21, Volume: 86, Issue:3-4

    Topics: Aminopeptidases; Analgesics; Animals; Brain; Drug Synergism; Enkephalins; Hydrolysis; In Vitro Techniques; Leucine; Male; Mice; Mice, Inbred Strains; Puromycin; Rats; Rats, Inbred Strains; Thiorphan; Tiopronin

1983
Purification and characterization of enkephalin-degradating enzymes from calf-brain striatum.
    Biochemical and biophysical research communications, 1983, Sep-15, Volume: 115, Issue:2

    Topics: Aminopeptidases; Animals; Cattle; Corpus Striatum; Dipeptides; Enkephalin, Leucine; Kinetics; Thiorphan; Tiopronin; Tissue Distribution

1983
Involvement of endogenous enkephalins in the mouse 'behavioral despair' test.
    European journal of pharmacology, 1984, Jan-27, Volume: 97, Issue:3-4

    Topics: Aminopeptidases; Animals; Behavior, Animal; Enkephalin, Methionine; Enkephalins; Leucine; Male; Mice; Motor Activity; Naloxone; Protease Inhibitors; Thiorphan; Tiopronin

1984
The inhibitory effect of opioid peptides and morphine applied intrathecally and intracerebroventricularly on the micturition reflex in the cat.
    Brain research, 1984, Apr-23, Volume: 298, Issue:1

    Topics: Animals; Cats; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Enkephalins; Female; Morphine; Naloxone; Oligopeptides; Reflex; Thiorphan; Tiopronin; Urination

1984
Changes in turnover of cerebral monoamines following inhibition of enkephalin metabolism by thiorphan and bestatin.
    European journal of pharmacology, 1984, Sep-17, Volume: 104, Issue:3-4

    Topics: alpha-Methyltyrosine; Amino Acids, Sulfur; Aminopeptidases; Animals; Biogenic Amines; Brain; Enkephalins; Leucine; Male; Methyltyrosines; Mice; Naloxone; Protease Inhibitors; Thiorphan; Tiopronin

1984
Nociception, enkephalin content and dipeptidyl carboxypeptidase activity in brain of mice treated with exopeptidase inhibitors.
    Neuropharmacology, 1982, Volume: 21, Issue:7

    Topics: Animals; Brain; Corpus Striatum; Endopeptidases; Enkephalin, Methionine; Enkephalins; Exopeptidases; Female; Leucine; Mice; Neprilysin; Nociceptors; Protease Inhibitors; Thiorphan; Tiopronin

1982
In vitro and in vivo effects of thiorphan: an inhibitor of enkephalinase A.
    Advances in biochemical psychopharmacology, 1982, Volume: 33

    Topics: Amino Acids, Sulfur; Aminopeptidases; Analgesics; Animals; Captopril; Drug Synergism; Enkephalins; In Vitro Techniques; Male; Mice; Naloxone; Neprilysin; Protease Inhibitors; Thiorphan; Tiopronin

1982
Phasic enkephalinergic modulation of nigrostriatal dopamine metabolism: potentiation with enkephalinase inhibitors.
    European journal of pharmacology, 1982, Aug-13, Volume: 82, Issue:1-2

    Topics: Animals; Corpus Striatum; Dopamine; Enkephalins; Hydroxamic Acids; Male; Neprilysin; Protease Inhibitors; Rats; Rats, Inbred Strains; Substantia Nigra; Thiorphan; Tiopronin

1982
The enkephalinase inhibitor thiorphan shows antinociceptive activity in mice.
    Nature, 1980, Nov-20, Volume: 288, Issue:5788

    Topics: Amino Acids, Sulfur; Analgesia; Animals; Binding Sites; Dose-Response Relationship, Drug; Drug Synergism; Endorphins; Enkephalins; Mice; Neprilysin; Nociceptors; Protease Inhibitors; Thiorphan; Tiopronin

1980
Selective protection of methionine enkephalin released from brain slices by enkephalinase inhibition.
    Science (New York, N.Y.), 1981, Jun-05, Volume: 212, Issue:4499

    Topics: Amino Acids, Sulfur; Animals; Corpus Striatum; Endorphins; Enkephalin, Methionine; Enkephalins; Mice; Neprilysin; Potassium; Protease Inhibitors; Rats; Thiorphan; Tiopronin

1981
Effects of thiorphan on the antinociceptive actions of intrathecal [D-Ala2,Met5] enkephalin.
    European journal of pharmacology, 1982, Apr-23, Volume: 79, Issue:3-4

    Topics: Amino Acids, Sulfur; Analgesics; Animals; Captopril; Drug Interactions; Endorphins; Enkephalin, Methionine; Enkephalins; Female; Injections, Spinal; Macaca; Morphine; Neprilysin; Protease Inhibitors; Rats; Species Specificity; Thiorphan; Tiopronin

1982
Kidney neutral endopeptidase and the hydrolysis of enkephalin by synaptic membranes show similar sensitivity to inhibitors.
    The Biochemical journal, 1982, May-01, Volume: 203, Issue:2

    Topics: Animals; Endorphins; Enkephalin, Leucine; Enkephalins; Glycopeptides; Hydrolysis; Kidney; Neprilysin; Organophosphorus Compounds; Protease Inhibitors; Swine; Synaptic Membranes; Thermolysin; Thiorphan; Tiopronin

1982