enkephalin, leucine has been researched along with sufentanil in 29 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (34.48) | 18.7374 |
| 1990's | 19 (65.52) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gintzler, AR; Xu, H | 3 |
| Connelly, CD; Martinez, RP; Raffa, RB | 2 |
| Mjanger, E; Yaksh, TL | 1 |
| Elde, RP; Lacey, CB; Miller, KE; Seybold, VS; Stevens, CW | 1 |
| Bennett, GJ; Kajander, KC; Seybold, VS; Stevens, CW | 1 |
| Cowan, A; Murray, CW | 1 |
| Ayesta, FJ; Flórez, J | 1 |
| Yaksh, TL | 1 |
| Stevens, CW; Yaksh, TL | 2 |
| Rooney, KF; Sewell, RD | 1 |
| Gintzler, AR; Smolens, I; Xu, H | 1 |
| Galzi, JL; Goeldner, M; Hirth, C; Ilien, B; Mejean, A | 1 |
| Jensen, TS; Yaksh, TL | 1 |
| Carter, BD; Clark, MJ; Medzihradsky, F | 1 |
| Day, AR; Freer, RJ; Liao, CS | 1 |
| Herz, A; Krenss, H; Schulz, R; Wüster, M | 1 |
| Diaz, A; Flórez, J; Hurlé, MA; Pazos, A; Ruiz, F | 1 |
| Chen, C; de Riel, JK; Kunapuli, SP; Liu-Chen, LY; Xue, JC; Yu, L; Zhu, J | 1 |
| Gintzler, AR; Wang, L | 1 |
| Garaulet, JV; Laorden, ML; Milanés, MV | 1 |
| Saeki, S; Yaksh, TL | 1 |
| Lazar, DF; Medzihradsky, F | 1 |
| Goode, TL; Raffa, RB | 1 |
| Cheung, P; Li, JG; Liu-Chen, LY; Raffa, RB; Tzeng, TB | 1 |
| Clark, MJ; Emmerson, PJ; Medzihradsky, F; Remmers, AE | 1 |
29 other study(ies) available for enkephalin, leucine and sufentanil
| Article | Year |
|---|---|
Opioid enhancement of evoked [Met5]enkephalin release requires activation of cholinergic receptors: possible involvement of intracellular calcium.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Atropine; Calcimycin; Calcium; Colforsin; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Methionine; Enkephalins; Evoked Potentials; Fentanyl; Guinea Pigs; Hexamethonium Compounds; In Vitro Techniques; Myenteric Plexus; Naloxone; Pyrrolidines; Receptors, Muscarinic; Receptors, Opioid; Sufentanil | 1992 |
Opioid efficacy is linked to the LiCl-sensitive, inositol-1,4,5-trisphosphate-restorable pathway.
Topics: Analgesics; Animals; Chlorides; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Injections, Intraventricular; Inositol 1,4,5-Trisphosphate; Lithium; Lithium Chloride; Male; Mice; Morphine; Second Messenger Systems; Sufentanil | 1992 |
Characteristics of dose-dependent antagonism by beta-funaltrexamine of the antinociceptive effects of intrathecal mu agonists.
Topics: Analgesics; Animals; Binding, Competitive; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Fentanyl; Injections, Spinal; Male; Morphine; Naltrexone; Narcotic Antagonists; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, mu; Spinal Cord; Sufentanil | 1991 |
Biochemical characterization and regional quantification of mu, delta and kappa opioid binding sites in rat spinal cord.
Topics: Analgesics; Animals; Autoradiography; Benzeneacetamides; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Fentanyl; Kinetics; Male; Pyrrolidines; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Spinal Cord; Sufentanil; Tritium | 1991 |
Bilateral and differential changes in spinal mu, delta and kappa opioid binding in rats with a painful, unilateral neuropathy.
Topics: Analgesics; Animals; Autoradiography; Behavior, Animal; Benzeneacetamides; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Fentanyl; Ligands; Male; Nervous System Diseases; Pain; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Sensory Thresholds; Spinal Cord; Sufentanil | 1991 |
Opioids can produce a concentration-dependent naloxone-reversible enhancement of inhibition of evoked enkephalin release.
Topics: Analgesics; Animals; Cholera Toxin; Colforsin; Cyclic AMP; Dynorphins; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Methionine; Enkephalins; Fentanyl; Guinea Pigs; In Vitro Techniques; Myenteric Plexus; Naloxone; Narcotics; Parasympatholytics; Sufentanil; Thionucleotides; Virulence Factors, Bordetella | 1990 |
Different G proteins mediate the opioid inhibition or enhancement of evoked [5-methionine]enkephalin release.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Dose-Response Relationship, Drug; Electric Stimulation; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Methionine; Enkephalins; Fentanyl; GTP-Binding Proteins; Guinea Pigs; In Vitro Techniques; Kinetics; Muscle, Smooth; Myenteric Plexus; Narcotics; Pertussis Toxin; Pyrrolidines; Sufentanil; Virulence Factors, Bordetella | 1991 |
Tonic pain perception in the mouse: differential modulation by three receptor-selective opioid agonists.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Dose-Response Relationship, Drug; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Fentanyl; Injections, Intraventricular; Male; Mice; Mice, Inbred ICR; Pain; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Sufentanil | 1991 |
Tolerance to the respiratory actions of opiates: withdrawal tolerance and asymmetrical cross-tolerance.
Topics: Animals; Dose-Response Relationship, Drug; Drug Tolerance; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Fentanyl; Injections, Intravenous; Injections, Intraventricular; Injections, Subcutaneous; Male; Morphine; Narcotics; Rats; Rats, Inbred Strains; Respiratory System; Substance Withdrawal Syndrome; Sufentanil | 1990 |
Substance P release from knee joint afferent terminals: modulation by opioids.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Afferent Pathways; Animals; Capsaicin; Cats; Electric Stimulation; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Fentanyl; Hindlimb; Joints; Narcotics; Pyrrolidines; Reference Values; Sciatic Nerve; Substance P; Sufentanil | 1988 |
Potency of infused spinal antinociceptive agents is inversely related to magnitude of tolerance after continuous infusion.
Topics: Analgesics; Animals; Clonidine; Drug Tolerance; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Fentanyl; Infusions, Parenteral; Male; Morphine; Pain; Rats; Rats, Inbred Strains; Reference Values; Sufentanil | 1989 |
Magnitude of opioid dependence after continuous intrathecal infusion of mu- and delta-selective opioids in the rat.
Topics: Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Fentanyl; Injections, Spinal; Male; Morphine; Naloxone; Narcotics; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Substance Withdrawal Syndrome; Substance-Related Disorders; Sufentanil; Time Factors | 1989 |
Evaluation of selective actions of dopamine D-1 and D-2 receptor agonists and antagonists on opioid antinociception.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Dopamine Agents; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Ergolines; Fentanyl; Injections, Intraventricular; Male; Mice; Narcotics; Nociceptors; Pyrrolidines; Quinpirole; Reaction Time; Receptors, Dopamine; Sufentanil; Sulpiride | 1989 |
Opioids can enhance and inhibit the electrically evoked release of methionine-enkephalin.
Topics: Action Potentials; Animals; Colforsin; Cyclic AMP; Dynorphins; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Methionine; Enkephalins; Fentanyl; Guinea Pigs; Myenteric Plexus; Naloxone; Sufentanil | 1989 |
A mu-opioid receptor-filter assay. Rapid estimation of binding affinity of ligands and reversibility of long-lasting ligand-receptor complexes.
Topics: Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Fentanyl; Filtration; In Vitro Techniques; Kinetics; Male; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, mu; Sufentanil | 1988 |
Comparison of the antinociceptive action of mu and delta opioid receptor ligands in the periaqueductal gray matter, medial and paramedial ventral medulla in the rat as studied by the microinjection technique.
Topics: Analgesics, Opioid; Animals; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Fentanyl; Male; Medulla Oblongata; Morphine; Naloxone; Oligopeptides; Periaqueductal Gray; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Sufentanil | 1986 |
Selectivity of ligand binding to opioid receptors in brain membranes from the rat, monkey and guinea pig.
Topics: Analgesics, Opioid; Animals; Benzeneacetamides; Brain Chemistry; Cell Membrane; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Fentanyl; Guinea Pigs; Haplorhini; Pyrrolidines; Radioligand Assay; Rats; Receptors, Opioid; Sufentanil; Tritium | 1988 |
Evidence for a single opioid receptor type on the field stimulated rat vas deferens.
Topics: Animals; Benzimidazoles; beta-Endorphin; Dose-Response Relationship, Drug; Electric Stimulation; Endorphins; Enkephalins; Etorphine; Fentanyl; Male; Morphine; Oxymorphone; Rats; Rats, Inbred Strains; Receptors, Opioid; Sufentanil; Vas Deferens | 1981 |
Selective development of tolerance without dependence in multiple opiate receptors of mouse vas deferens.
Topics: Animals; Dose-Response Relationship, Drug; Drug Tolerance; Electric Stimulation; Endorphins; Enkephalin, Leucine-2-Alanine; Enkephalins; Fentanyl; Humans; Male; Mice; Muscle Contraction; Muscle, Smooth; Receptors, Opioid; Substance-Related Disorders; Sufentanil; Vas Deferens | 1980 |
Mu-opioid receptor regulation during opioid tolerance and supersensitivity in rat central nervous system.
Topics: Analgesics, Opioid; Animals; Autoradiography; Calcium Channel Blockers; Calcium Channels; Central Nervous System; Drug Tolerance; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Male; Nimodipine; Rats; Rats, Wistar; Receptors, Opioid, mu; Sufentanil | 1995 |
The third extracellular loop of the mu opioid receptor is important for agonist selectivity.
Topics: Amino Acid Sequence; Animals; Binding Sites; Cell Line; Diprenorphine; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Molecular Sequence Data; Morphine; Protein Conformation; Rats; Receptors, Opioid, mu; Sufentanil | 1995 |
G-protein antisense oligodeoxyribonucleotides and mu-opioid supraspinal antinociception.
Topics: Analgesics; Animals; Base Sequence; Drug Interactions; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; GTP-Binding Proteins; Injections, Intraventricular; Male; Mice; Molecular Sequence Data; Morphine; Oligonucleotides, Antisense; Receptors, Opioid, mu; Sufentanil | 1994 |
Bimodal opioid regulation of cyclic AMP formation: implications for positive and negative coupling of opiate receptors to adenylyl cyclase.
Topics: Adenylyl Cyclases; Animals; Cyclic AMP; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Enkephalins; Humans; Muscles; Myenteric Plexus; Naloxone; Narcotics; Radioimmunoassay; Receptors, Opioid; Sufentanil | 1994 |
Cross-tolerance between mu- and kappa-opioid agonists in the guinea pig ileum myenteric plexus.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Dose-Response Relationship, Drug; Drug Tolerance; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Female; Guinea Pigs; Ileum; In Vitro Techniques; Male; Morphine; Myenteric Plexus; Narcotics; Pyrrolidines; Receptors, Opioid, kappa; Receptors, Opioid, mu; Sufentanil | 1994 |
Suppression of nociceptive responses by spinal mu opioid agonists: effects of stimulus intensity and agonist efficacy.
Topics: Animals; Dose-Response Relationship, Drug; Enkephalins; Hemodynamics; Injections, Spinal; Male; Morphine; Pain; Rats; Rats, Sprague-Dawley; Sufentanil | 1993 |
Altered transition between agonist- and antagonist-favoring states of mu-opioid receptor in brain membranes with modified microviscosity.
Topics: Animals; Brain; Cholesterol Esters; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Etorphine; Male; Membrane Fluidity; Membranes; Naltrexone; Oleic Acid; Oleic Acids; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Sodium Chloride; Sufentanil; Viscosity | 1993 |
An examination of the relationship between mu-opioid antinociceptive efficacy and G-protein coupling using pertussis and cholera toxins.
Topics: Analgesics; Animals; Cholera Toxin; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; GTP-Binding Proteins; Injections, Intraventricular; Male; Mice; Morphine; Pertussis Toxin; Receptors, Opioid, mu; Sufentanil; Virulence Factors, Bordetella | 1997 |
Apparent thermodynamic parameters of ligand binding to the cloned rat mu-opioid receptor.
Topics: Analgesics; Animals; Binding, Competitive; CHO Cells; Cricetinae; Diprenorphine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Fentanyl; Ligands; Methadone; Morphine; Naltrexone; Narcotic Antagonists; Pentazocine; Peptide Fragments; Peptides; Radioligand Assay; Rats; Receptors, Opioid, mu; Somatostatin; Sufentanil; Thermodynamics; Time Factors | 1998 |
Membrane microviscosity modulates mu-opioid receptor conformational transitions and agonist efficacy.
Topics: Animals; Cell Line; Cell Membrane; Cholesterol Esters; Diprenorphine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Glioma; Guanosine 5'-O-(3-Thiotriphosphate); Membrane Fluidity; Nalbuphine; Naltrexone; Narcotic Antagonists; Narcotics; Neuroblastoma; Protein Conformation; Rats; Receptors, Opioid, mu; Sodium Chloride; Sufentanil; Tumor Cells, Cultured; Viscosity | 1999 |