enkephalin, leucine and s,n,n'-tripropylthiocarbamate

enkephalin, leucine has been researched along with s,n,n'-tripropylthiocarbamate in 53 studies

Research

Studies (53)

TimeframeStudies, this research(%)All Research%
pre-19907 (13.21)18.7374
1990's10 (18.87)18.2507
2000's14 (26.42)29.6817
2010's18 (33.96)24.3611
2020's4 (7.55)2.80

Authors

AuthorsStudies
Belluzzi, JD; Stein, L1
Stein, L1
De Witte, P; Gewiss, M; Heidbreder, C; Lallemand, S; Roques, BP1
Cunningham, ST; Kelley, AE1
Gratton, A; Jenck, F; Wise, RA1
Bak, TH; Carr, KD1
Iwamoto, ET1
Cooper, SJ1
LePiane, FG; Phillips, AG1
Johnson, PI; Stellar, JR1
Baumeister, AA; Chaney, TM; Curtis, W; Hurry, M; Leoni, RR; Wolf, E1
Johnson, PI; Paul, AD; Stellar, JR1
Endoh, T; Misawa, M; Mori, T; Nagase, H; Suzuki, T; Tsuji, M1
Befort, K; Dierich, A; Dollé, P; Hanoune, J; Kieffer, BL; Kitchen, I; Le Meur, M; Maldonado, R; Matthes, HW; Roques, BP; Simonin, F; Slowe, S; Tzavara, E; Valverde, O1
Duvauchelle, CL; Fleming, SM; Kornetsky, C2
Ikeda, H; Misawa, M; Mori, T; Nagase, H; Suzuki, T; Tsuji, M1
Roques, BP1
Cupo, A; Nieto, MM; Noble, F; Roques, BP; Wilson, J1
Koenig, HN; Olive, MF1
Brené, S; Gilden, L; Messer, C; Nestler, EJ; Olson, L; Thorén, P; Werme, M1
Hayward, MD; Low, MJ; Pintar, JE1
Chavkin, C; Marton-Popovici, M; McLaughlin, JP1
Avena, NM; Goddard, NL; Hoebel, BG; Leibowitz, SF; Spangler, R; Wittkowski, KM1
Berrendero, F; Bilkei-Gorzo, A; Galeote, L; Maldonado, R; Mendizábal, V; Robledo, P; Zimmer, A1
Alvaro, JD; Duman, RS; Haile, C; Han, G; Hruby, VJ; Hsu, R; Nestler, EJ; Newton, SS; Taylor, JR1
Baldo, BA; Kelley, AE; Pratt, WE1
Carr, KD; Haberny, SL1
Hayward, MD; Low, MJ1
Berridge, KC; Smith, KS1
Bearzatto, B; Buch, T; de Kerchove d'Exaerde, A; Durieux, PF; Guiducci, S; Schiffmann, SN; Waisman, A; Zoli, M1
Gieryk, A; Kubik, J; Przewlocki, R; Solecki, W; Ziolkowska, B1
Carey, AN; Gomes, SM; McLaughlin, JP; Sperling, RE; Sypek, EI1
Johansson, B; Terenius, L1
Aoki, Y; Ishikawa, M; Kanno, S; Mizoguchi, H; Natsui, S; Osada, S; Sakurada, S; Sakurada, T; Watanabe, C; Yonezawa, A; Yoshioka, M1
Furlong, TM; Marchant, NJ; McNally, GP1
Balleine, BW; Cely, IC; Maidment, NT; Wassum, KM1
Christiansen, AM; Herman, JP; Ulrich-Lai, YM1
Casaccia, P; DiNieri, JA; Dow-Edwards, D; Hurd, YL; Kaur, J; Spano, SM; Szutorisz, H; Wang, X1
Bakalkin, G; Bazov, I; Hussain, MZ; Kononenko, O; Kuntić, V; Nyberg, F; Sarkisyan, D; Taqi, MM; Watanabe, H; Yakovleva, T1
Femenía, T; Manzanares, J1
Garg, M; Hamid, A; Lutfy, K; Marquez, P; Nguyen, K; Tseng, A1
Baldo, BA; Benca, RM; Bremer, Q; Hanlon, EC; Obermeyer, W; Paletz, E1
Cepeda, C; Cui, Y; Evans, CJ; Ge, W; James, AS; Jentsch, JD; Kieffer, BL; Levine, MS; Maidment, NT; Mittal, N; Murphy, NP; Ostlund, SB; Park, CS; Roberts, KW; Sun, YE; Walwyn, WM; Yang, XW1
Gugusheff, JR; Muhlhausler, BS; Ong, ZY1
Cordes, MA; DeVries, MS; Riters, LV; Stevenson, SA1
Kroll, SL; Lamm, C; Pfabigan, DM; Pripfl, J; Sailer, U1
Carboni, L; Romoli, B; Romualdi, P; Zoli, M1
Graybiel, AM; Kitsukawa, T; Nagata, M; Nakamura, T; Yagi, T; Yamamori, T1
Clark, JD; Nwaneshiudu, CA; Shi, XY1
Bruchas, MR; Castro, DC; Guglin, A; Hunker, AC; Morón, JA; Oswell, CS; Pedersen, CE; Piantadosi, SC; Rossi, MA; Stuber, GD; Zhang, ET; Zweifel, LS1
Alvarez, VA; Blegen, MB; Bocarsly, ME; Choi, IB; Dai, KZ; Dobbs, LK; Kaplan, AR; Kellendonk, C; Levitt, R; Matsui, A; Shin, JH; Simpson, EH1
Asokan, M; Choi, IB; Dobbs, LK; Le, NN; Matsumura, K; Natividad, LA; Nicot, A1

Reviews

3 review(s) available for enkephalin, leucine and s,n,n'-tripropylthiocarbamate

ArticleYear
Minireview. Benzodiazepine-opiate antagonist interactions in relation to feeding and drinking behavior.
    Life sciences, 1983, Mar-07, Volume: 32, Issue:10

    Topics: Animals; Benzodiazepines; Corpus Striatum; Drinking Behavior; Enkephalins; Feeding Behavior; Food Deprivation; Humans; Hyperphagia; Motor Activity; Naloxone; Naltrexone; Narcotic Antagonists; Reward; Thirst

1983
Novel approaches to targeting neuropeptide systems.
    Trends in pharmacological sciences, 2000, Volume: 21, Issue:12

    Topics: Animals; Anxiety; Depression; Dopamine; Enkephalins; Enzyme Inhibitors; Humans; Metalloendopeptidases; Mice; Neuropeptides; Pain; Protease Inhibitors; Receptors, Cholecystokinin; Receptors, Opioid; Reward; Sincalide; Substance-Related Disorders

2000
The opioid systems--panacea and nemesis.
    Biochemical and biophysical research communications, 2010, May-21, Volume: 396, Issue:1

    Topics: Allostasis; Analgesics, Opioid; Animals; Behavior, Addictive; Conditioning, Classical; Enkephalins; Humans; Mice; Opioid Peptides; Opioid-Related Disorders; Pro-Opiomelanocortin; Protein Precursors; Rats; Receptors, Opioid, mu; Reward

2010

Other Studies

50 other study(ies) available for enkephalin, leucine and s,n,n'-tripropylthiocarbamate

ArticleYear
Brain endorphins: possible role in reward and memory formation.
    Federation proceedings, 1979, Volume: 38, Issue:11

    Topics: Animals; Avoidance Learning; Brain; Electric Stimulation; Endorphins; Enkephalins; Globus Pallidus; Memory; Naloxone; Neurotransmitter Agents; Rats; Receptors, Opioid; Reward; Self Stimulation

1979
Brain endorphins: possible mediators of pleasure and reward.
    Neurosciences Research Program bulletin, 1978, Volume: 16, Issue:4

    Topics: Animals; Brain; Ditiocarb; Dose-Response Relationship, Drug; Electric Stimulation; Endorphins; Enkephalins; Injections, Intraventricular; Memory; Naloxone; Rats; Reinforcement, Psychology; Reward; Self Stimulation; Substance P

1978
Inhibition of enkephalin metabolism and activation of mu- or delta-opioid receptors elicit opposite effects on reward and motility in the ventral mesencephalon.
    Neuropharmacology, 1992, Volume: 31, Issue:3

    Topics: Animals; Brain; Dipeptides; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Male; Mesencephalon; Motor Activity; Oligopeptides; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Reward; Self Stimulation

1992
Evidence for opiate-dopamine cross-sensitization in nucleus accumbens: studies of conditioned reward.
    Brain research bulletin, 1992, Volume: 29, Issue:5

    Topics: Animals; Conditioning, Operant; Dextroamphetamine; Dopamine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Male; Morphine; Narcotics; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Reward

1992
Opioid receptor subtypes associated with ventral tegmental facilitation of lateral hypothalamic brain stimulation reward.
    Brain research, 1987, Oct-13, Volume: 423, Issue:1-2

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Electric Stimulation; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Hypothalamic Area, Lateral; Male; Morphine; Pyrrolidines; Rats; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Reward

1987
Medial thalamic injection of opioid agonists: mu-agonist increases while kappa-agonist decreases stimulus thresholds for pain and reward.
    Brain research, 1988, Feb-16, Volume: 441, Issue:1-2

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Electric Stimulation; Electroshock; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Infusions, Parenteral; Male; Microinjections; Naloxone; Pain; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Reward; Self Stimulation; Thalamus

1988
Dynorphin A [1-17] induces "reward" in rats in the place conditioning paradigm.
    Life sciences, 1988, Volume: 43, Issue:6

    Topics: Animals; Conditioning, Psychological; Dose-Response Relationship, Drug; Dynorphins; Enkephalin, Leucine; Injections, Intraventricular; Male; Naloxone; Rats; Rats, Inbred Strains; Reward

1988
Reward produced by microinjection of (D-Ala2),Met5-enkephalinamide into the ventral tegmental area.
    Behavioural brain research, 1982, Volume: 5, Issue:2

    Topics: Animals; Conditioning, Operant; Endorphins; Enkephalin, Methionine; Enkephalins; Male; Naloxone; Rats; Reward; Tegmentum Mesencephali

1982
Comparison of delta opiate receptor agonist induced reward and motor effects between the ventral pallidum and dorsal striatum.
    Neuropharmacology, 1994, Volume: 33, Issue:10

    Topics: Animals; Caudate Nucleus; Conditioning, Operant; Corpus Striatum; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Male; Microinjections; Rats; Receptors, Opioid, delta; Reward; Self Stimulation

1994
The antinociceptive and motivational effects of intranigral injection of opioid agonists.
    Neuropharmacology, 1993, Volume: 32, Issue:12

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Analysis of Variance; Animals; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Male; Microinjections; Morphine; Morphine Derivatives; Motivation; Pain; Periaqueductal Gray; Pyrrolidines; Rats; Rats, Sprague-Dawley; Reward; Stereotaxic Techniques; Substantia Nigra; Time Factors

1993
Regional reward differences within the ventral pallidum are revealed by microinjections of a mu opiate receptor agonist.
    Neuropharmacology, 1993, Volume: 32, Issue:12

    Topics: Analgesics; Analysis of Variance; Animals; Brain; Dose-Response Relationship, Drug; Electric Stimulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Globus Pallidus; Male; Microinjections; Motor Activity; Organ Specificity; Rats; Receptors, Opioid, mu; Reinforcement, Psychology; Reward; Self Stimulation

1993
Effect of the highly selective and nonpeptide delta opioid receptor agonist TAN-67 on the morphine-induced place preference in mice.
    The Journal of pharmacology and experimental therapeutics, 1996, Volume: 279, Issue:1

    Topics: Analgesics; Animals; Benzylidene Compounds; Dopamine; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Limbic System; Male; Mice; Morphine; Naltrexone; Quinolines; Receptors, Opioid, delta; Reward

1996
Loss of morphine-induced analgesia, reward effect and withdrawal symptoms in mice lacking the mu-opioid-receptor gene.
    Nature, 1996, Oct-31, Volume: 383, Issue:6603

    Topics: Analgesics; Animals; Behavior, Animal; Cell Line; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Gene Deletion; Mice; Mice, Inbred C57BL; Mice, Knockout; Morphine; Morphine Dependence; Narcotics; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Reward; Substance Withdrawal Syndrome

1996
Involvement of delta- and mu-opioid receptors in the potentiation of brain-stimulation reward.
    European journal of pharmacology, 1996, Dec-05, Volume: 316, Issue:2-3

    Topics: Analgesics; Animals; Brain; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Male; Rats; Rats, Inbred F344; Receptors, Opioid, delta; Receptors, Opioid, mu; Reward

1996
Involvement of dopamine-dependent and -independent mechanisms in the rewarding effects mediated by delta opioid receptor subtypes in mice.
    Brain research, 1997, Jan-09, Volume: 744, Issue:2

    Topics: Analgesics; Animals; Dopamine; Dose-Response Relationship, Drug; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Male; Mice; Receptors, Opioid, delta; Reward

1997
DAMGO and DPDPE facilitation of brain stimulation reward thresholds is blocked by the dopamine antagonist cis-flupenthixol.
    Neuropharmacology, 1997, Volume: 36, Issue:8

    Topics: Animals; Brain; Dopamine Antagonists; Drug Antagonism; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Flupenthixol; Injections; Male; Nucleus Accumbens; Rats; Rats, Inbred F344; Receptors, Opioid, delta; Receptors, Opioid, mu; Reward; Self Stimulation; Synaptic Transmission

1997
Chronic morphine treatment modulates the extracellular levels of endogenous enkephalins in rat brain structures involved in opiate dependence: a microdialysis study.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2002, Feb-01, Volume: 22, Issue:3

    Topics: Animals; Behavior, Animal; Brain; Brain Chemistry; Cholecystokinin; Conditioning, Psychological; Drug Administration Schedule; Enkephalins; Extracellular Space; Hippocampus; Male; Microdialysis; Morphine; Morphine Dependence; Nucleus Accumbens; Opioid Peptides; Periaqueductal Gray; Rats; Rats, Wistar; Reward; Substance Withdrawal Syndrome; Wakefulness

2002
Ethanol consumption patterns and conditioned place preference in mice lacking preproenkephalin.
    Neuroscience letters, 2002, Jun-07, Volume: 325, Issue:2

    Topics: Alcohol Drinking; Animals; Choice Behavior; Conditioning, Psychological; Enkephalins; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Protein Precursors; Reward

2002
Delta FosB regulates wheel running.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2002, Sep-15, Volume: 22, Issue:18

    Topics: Animals; Behavior, Animal; Caudate Nucleus; Cell Count; Corpus Striatum; Doxycycline; Dynorphins; Enkephalins; Gene Expression; Immunohistochemistry; In Situ Hybridization; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Motor Activity; Neurons; Nucleus Accumbens; Proto-Oncogene Proteins c-fos; Putamen; Rats; Rats, Inbred Lew; Reward; RNA, Messenger

2002
Selective reward deficit in mice lacking beta-endorphin and enkephalin.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2002, Sep-15, Volume: 22, Issue:18

    Topics: Animals; Behavior, Animal; beta-Endorphin; Choice Behavior; Conditioning, Operant; Eating; Enkephalins; Extinction, Psychological; Feeding Behavior; Food Deprivation; Genotype; Male; Mice; Mice, Knockout; Motivation; Phenotype; Reward

2002
Kappa opioid receptor antagonism and prodynorphin gene disruption block stress-induced behavioral responses.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2003, Jul-02, Volume: 23, Issue:13

    Topics: Analgesia; Animals; Behavior, Animal; Cocaine; Drug Synergism; Enkephalins; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Naltrexone; Narcotic Antagonists; Pain Threshold; Protein Precursors; Reaction Time; Receptors, Opioid, kappa; Reward; Spatial Behavior; Stress, Physiological; Swimming

2003
Opiate-like effects of sugar on gene expression in reward areas of the rat brain.
    Brain research. Molecular brain research, 2004, May-19, Volume: 124, Issue:2

    Topics: Animals; Brain; Down-Regulation; Enkephalins; Feeding and Eating Disorders; Gene Expression; Gene Expression Profiling; Male; Morphine; Neural Pathways; Nucleus Accumbens; Opioid Peptides; Protein Precursors; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Receptors, Dopamine D3; Reward; RNA, Messenger; Substance-Related Disorders; Sucrose; Tachykinins; Up-Regulation

2004
Nicotine-induced antinociception, rewarding effects, and physical dependence are decreased in mice lacking the preproenkephalin gene.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2005, Feb-02, Volume: 25, Issue:5

    Topics: Analgesics; Animals; Conditioning, Classical; Dopamine; Enkephalins; Female; Hot Temperature; Male; Mecamylamine; Mice; Mice, Inbred C57BL; Mice, Knockout; Microdialysis; Motor Activity; Nicotine; Nucleus Accumbens; Opioid Peptides; Pain Measurement; Pain Threshold; Protein Precursors; Reward; Spatial Behavior; Substance Withdrawal Syndrome; Tobacco Use Disorder

2005
Blockade of melanocortin transmission inhibits cocaine reward.
    The European journal of neuroscience, 2005, Volume: 21, Issue:8

    Topics: Agouti Signaling Protein; alpha-MSH; Animals; Behavior, Animal; Cocaine; Conditioning, Operant; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Enkephalins; In Situ Hybridization; Intercellular Signaling Peptides and Proteins; Melanocyte-Stimulating Hormones; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Nucleus Accumbens; Protein Precursors; Rats; Rats, Mutant Strains; Receptor, Melanocortin, Type 4; Reward; RNA, Messenger; Self Administration; Time Factors

2005
A proposed hypothalamic-thalamic-striatal axis for the integration of energy balance, arousal, and food reward.
    The Journal of comparative neurology, 2005, Dec-05, Volume: 493, Issue:1

    Topics: Acetylcholine; Animals; Arousal; Dopamine; Dynorphins; Energy Metabolism; Enkephalins; Food; Hypothalamus; Models, Biological; Narcotics; Nucleus Accumbens; Protein Precursors; Rats; Receptors, Opioid, kappa; Reward; RNA, Messenger; Thalamus

2005
Comparison of basal and D-1 dopamine receptor agonist-stimulated neuropeptide gene expression in caudate-putamen and nucleus accumbens of ad libitum fed and food-restricted rats.
    Brain research. Molecular brain research, 2005, Nov-30, Volume: 141, Issue:2

    Topics: Animals; Benzazepines; Caudate Nucleus; Dopamine Agonists; Dynorphins; Eating; Enkephalins; Food Deprivation; Gene Expression Regulation; Genes, fos; Injections, Intraventricular; Male; Neuropeptides; Nucleus Accumbens; Protein Precursors; Proto-Oncogene Proteins c-fos; Putamen; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Reward; RNA, Messenger; Signal Transduction; Stimulation, Chemical; Tachykinins

2005
The contribution of endogenous opioids to food reward is dependent on sex and background strain.
    Neuroscience, 2007, Jan-05, Volume: 144, Issue:1

    Topics: Animals; beta-Endorphin; Conditioning, Operant; Enkephalins; Female; Food; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Knockout; Reinforcement Schedule; Reward; Sex Characteristics; Species Specificity

2007
Opioid limbic circuit for reward: interaction between hedonic hotspots of nucleus accumbens and ventral pallidum.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2007, Feb-14, Volume: 27, Issue:7

    Topics: Analgesics, Opioid; Analysis of Variance; Animals; Behavior, Animal; Drug Interactions; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Feeding Behavior; Gene Expression Regulation; Globus Pallidus; Immunohistochemistry; Male; Naloxone; Narcotic Antagonists; Neural Pathways; Nucleus Accumbens; Oncogene Proteins v-fos; Rats; Rats, Sprague-Dawley; Reward; Taste

2007
D2R striatopallidal neurons inhibit both locomotor and drug reward processes.
    Nature neuroscience, 2009, Volume: 12, Issue:4

    Topics: Amphetamine; Animals; Autoradiography; Conditioning, Operant; Corpus Striatum; Diphtheria Toxin; Dopamine Uptake Inhibitors; Enkephalins; Gene Expression Regulation; Globus Pallidus; Glutamate Decarboxylase; Heparin-binding EGF-like Growth Factor; Intercellular Signaling Peptides and Proteins; Locomotion; Mice; Mice, Inbred C57BL; Mice, Transgenic; Nerve Tissue Proteins; Neurons; Protein Binding; Receptors, Adenosine A2; Receptors, Dopamine D2; Reinforcement Schedule; Reward; Time Factors; Tyrosine 3-Monooxygenase

2009
Forebrain PENK and PDYN gene expression levels in three inbred strains of mice and their relationship to genotype-dependent morphine reward sensitivity.
    Psychopharmacology, 2010, Volume: 208, Issue:2

    Topics: Animals; Behavior, Addictive; Behavior, Animal; Conditioning, Psychological; Cues; Enkephalins; Gene Expression Regulation; Genotype; In Situ Hybridization; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Morphine Dependence; Naltrexone; Narcotic Antagonists; Nucleus Accumbens; Phenotype; Protein Precursors; Receptors, Opioid, kappa; Reward; RNA, Messenger; Species Specificity

2010
Endogenous kappa-opioid mediation of stress-induced potentiation of ethanol-conditioned place preference and self-administration.
    Psychopharmacology, 2010, Volume: 210, Issue:2

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Conditioning, Psychological; Enkephalins; Ethanol; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Naltrexone; Protein Precursors; Receptors, Opioid, kappa; Reward; Self Administration; Signal Transduction; Stress, Physiological

2010
Lack of a rewarding effect and a locomotor-enhancing effect of the selective μ-opioid receptor agonist amidino-TAPA.
    Psychopharmacology, 2010, Volume: 212, Issue:2

    Topics: Analgesics, Opioid; Animals; Enkephalins; Injections, Subcutaneous; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Morphine; Motor Activity; Oligopeptides; Pain; Protein Precursors; Receptors, Opioid, mu; Reward; Time Factors

2010
Medial dorsal hypothalamus mediates the inhibition of reward seeking after extinction.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2010, Oct-20, Volume: 30, Issue:42

    Topics: Alcohol Drinking; Animals; Cell Count; Conditioning, Operant; Dorsomedial Hypothalamic Nucleus; Dose-Response Relationship, Drug; Enkephalins; Extinction, Psychological; Hydrogen-Ion Concentration; Immunohistochemistry; Injections, Intraventricular; Male; Nerve Net; Nerve Tissue Proteins; Neurons, Afferent; Neurons, Efferent; Protein Precursors; Proto-Oncogene Proteins c-fos; Rats; Rats, Long-Evans; Receptors, Opioid, kappa; Reward

2010
Micro-opioid receptor activation in the basolateral amygdala mediates the learning of increases but not decreases in the incentive value of a food reward.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2011, Feb-02, Volume: 31, Issue:5

    Topics: Amygdala; Animals; Conditioning, Operant; Drive; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Food; Guanidines; Male; Microinjections; Morphinans; Naltrexone; Narcotic Antagonists; Neuropsychological Tests; Rats; Rats, Long-Evans; Receptors, Opioid, kappa; Receptors, Opioid, mu; Reward; Somatostatin; Sucrose

2011
Regulatory interactions of stress and reward on rat forebrain opioidergic and GABAergic circuitry.
    Stress (Amsterdam, Netherlands), 2011, Volume: 14, Issue:2

    Topics: Animals; Enkephalins; Glutamate Decarboxylase; Male; Prosencephalon; Protein Precursors; Rats; Rats, Long-Evans; Reward; RNA, Messenger; Septal Nuclei; Stress, Psychological

2011
Maternal cannabis use alters ventral striatal dopamine D2 gene regulation in the offspring.
    Biological psychiatry, 2011, Oct-15, Volume: 70, Issue:8

    Topics: Alcohol Drinking; Animals; Animals, Newborn; Conditioning, Psychological; Dronabinol; Enkephalins; Epigenesis, Genetic; Female; Fetus; Gene Expression Regulation, Developmental; Humans; Male; Marijuana Abuse; Morphine; Nucleus Accumbens; Pregnancy; Prenatal Exposure Delayed Effects; Protein Precursors; Radioligand Assay; Radionuclide Imaging; Rats; Rats, Long-Evans; Receptors, Dopamine D2; Reward; Smoking

2011
The endogenous opioid system in human alcoholics: molecular adaptations in brain areas involved in cognitive control of addiction.
    Addiction biology, 2013, Volume: 18, Issue:1

    Topics: Adaptation, Physiological; Adult; Alcoholism; Analysis of Variance; Animals; Behavior, Addictive; Case-Control Studies; Dynorphins; Enkephalins; Hippocampus; Humans; Male; Opioid Peptides; Prefrontal Cortex; Protein Precursors; Radioimmunoassay; Receptors, Opioid; Reverse Transcriptase Polymerase Chain Reaction; Reward; RNA, Messenger; Statistics, Nonparametric; Up-Regulation

2013
Increased ethanol intake in prodynorphin knockout mice is associated to changes in opioid receptor function and dopamine transmission.
    Addiction biology, 2012, Volume: 17, Issue:2

    Topics: Alcohol Drinking; Animals; Autoradiography; Basal Ganglia; Body Temperature; Dopamine; Dopamine Plasma Membrane Transport Proteins; Enkephalins; Ethanol; Gene Expression; Guanosine 5'-O-(3-Thiotriphosphate); Hypothermia; In Situ Hybridization; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nucleus Accumbens; Protein Precursors; Receptors, Opioid; Reflex, Righting; Reinforcement, Psychology; Reward; Tyrosine 3-Monooxygenase; Unconsciousness

2012
The role of endogenous beta-endorphin and enkephalins in ethanol reward.
    Neuropharmacology, 2013, Volume: 73

    Topics: Animals; beta-Endorphin; Choice Behavior; Conditioning, Psychological; Dose-Response Relationship, Drug; Enkephalins; Ethanol; Female; Mice; Mice, Knockout; Naloxone; Narcotic Antagonists; Protein Precursors; Reward

2013
Upregulation of gene expression in reward-modulatory striatal opioid systems by sleep loss.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2013, Volume: 38, Issue:13

    Topics: Animals; Body Weight; Eating; Enkephalins; Fasting; Insulin; Leptin; Male; Neostriatum; Nerve Tissue Proteins; Neuroimaging; Neuropeptide Y; Opioid Peptides; Protein Precursors; Rats; Rats, Sprague-Dawley; Reward; Sleep Deprivation; Up-Regulation

2013
Targeted expression of μ-opioid receptors in a subset of striatal direct-pathway neurons restores opiate reward.
    Nature neuroscience, 2014, Volume: 17, Issue:2

    Topics: Analysis of Variance; Animals; Conditioning, Operant; Corpus Striatum; Disease Models, Animal; Dopamine; Enkephalins; Exploratory Behavior; Flow Cytometry; Green Fluorescent Proteins; Mice; Mice, Transgenic; Microdialysis; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Neural Pathways; Neurons; Pain; Pain Measurement; Protein Precursors; Receptors, Opioid, mu; Reward; Substance Withdrawal Syndrome

2014
Naloxone treatment alters gene expression in the mesolimbic reward system in 'junk food' exposed offspring in a sex-specific manner but does not affect food preferences in adulthood.
    Physiology & behavior, 2014, Jun-22, Volume: 133

    Topics: Animals; Diet, High-Fat; Dietary Sucrose; Dopamine Plasma Membrane Transport Proteins; Eating; Enkephalins; Feeding Behavior; Female; Food Preferences; Gene Expression Regulation; Male; Naloxone; Narcotic Antagonists; Nucleus Accumbens; Pregnancy; Prenatal Exposure Delayed Effects; Protein Precursors; Rats; Rats, Wistar; Receptors, Dopamine; Reward; RNA, Messenger; Sex Characteristics; Ventral Tegmental Area

2014
Reward associated with singing behavior correlates with opioid-related gene expression in the medial preoptic nucleus in male European starlings.
    PloS one, 2014, Volume: 9, Issue:12

    Topics: Animals; Enkephalins; Male; Preoptic Area; Protein Precursors; Receptors, Opioid, mu; Reward; RNA, Messenger; Starlings; Vocalization, Animal

2014
Event-related potentials in performance monitoring are influenced by the endogenous opioid system.
    Neuropsychologia, 2015, Volume: 77

    Topics: Adult; Brain; Choice Behavior; Double-Blind Method; Electroencephalography; Enkephalins; Evoked Potentials; Female; Genotyping Techniques; Humans; Male; Polymorphism, Genetic; Protein Precursors; Reaction Time; Reward; White People; Young Adult

2015
Repeated nicotine exposure modulates prodynorphin and pronociceptin levels in the reward pathway.
    Drug and alcohol dependence, 2016, Sep-01, Volume: 166

    Topics: Animals; Brain; Brain Mapping; Dopamine; Enkephalins; Gene Expression; Motivation; Motor Activity; Nerve Net; Nicotine; Nociceptin Receptor; Nucleus Accumbens; Opioid Peptides; Protein Precursors; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Receptors, Opioid, kappa; Reward; RNA, Messenger; Tobacco Use Disorder

2016
Learning new sequential stepping patterns requires striatal plasticity during the earliest phase of acquisition.
    The European journal of neuroscience, 2017, Volume: 45, Issue:7

    Topics: Animals; Corpus Striatum; Enkephalins; Learning; Mice; Mice, Inbred C57BL; Mice, Inbred ICR; Motor Cortex; Neuronal Plasticity; Neurons; Proto-Oncogene Proteins c-fos; Receptors, N-Methyl-D-Aspartate; Reward; Running; Substance P

2017
Incisional Injury Modulates Morphine Reward and Morphine-Primed Reinstatement: A Role of Kappa Opioid Receptor Activation.
    Anesthesia and analgesia, 2020, Volume: 130, Issue:1

    Topics: Acute Pain; Animals; Behavior, Animal; Conditioning, Psychological; Disease Models, Animal; Enkephalins; Extinction, Psychological; Male; Mice, Inbred C57BL; Morphine; Narcotic Antagonists; Pain Threshold; Protein Precursors; Receptors, Opioid, kappa; Reward; Signal Transduction; Wounds, Penetrating

2020
An endogenous opioid circuit determines state-dependent reward consumption.
    Nature, 2021, Volume: 598, Issue:7882

    Topics: Analgesics, Opioid; Animals; Enkephalins; Female; Male; Mice; Mice, Knockout; Nucleus Accumbens; Receptors, Opioid, mu; Reward

2021
Dopamine D2 receptors bidirectionally regulate striatal enkephalin expression: Implications for cocaine reward.
    Cell reports, 2022, 09-27, Volume: 40, Issue:13

    Topics: Analgesics, Opioid; Animals; Cocaine; Cocaine-Related Disorders; Corpus Striatum; Enkephalin, Methionine; Enkephalins; gamma-Aminobutyric Acid; Mice; Narcotic Antagonists; Receptors, Dopamine D1; Receptors, Dopamine D2; Reward; RNA, Messenger

2022
Endogenous opioid system modulates conditioned cocaine reward in a sex-dependent manner.
    Addiction biology, 2023, Volume: 28, Issue:10

    Topics: Analgesics, Opioid; Animals; Cocaine; Enkephalins; Female; Male; Mice; Naloxone; Narcotic Antagonists; Opioid Peptides; Reward

2023