enkephalin, leucine has been researched along with rimorphin in 77 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 39 (50.65) | 18.7374 |
1990's | 26 (33.77) | 18.2507 |
2000's | 11 (14.29) | 29.6817 |
2010's | 1 (1.30) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Deviche, P; Güntürkün, O | 1 |
Gannon, RL; Terrian, DM | 1 |
Nyberg, F; Silberring, J | 2 |
Demuth, HU; Nyberg, F | 1 |
Basbaum, AI; Cruz, L; Weber, E | 1 |
Murphy, R; Steele, PA; Turner, CA | 1 |
Neal, CR; Newman, SW | 1 |
Brownstein, MJ; Eiden, LE; Eskay, RL; Faden, AI; Feuerstein, G; Palkovits, M; Weber, E; Zamir, D; Zamir, N | 1 |
Gaudreau, P; Martel, JC; Quirion, R; St-Pierre, S; Zamir, N | 1 |
Altschuler, RA; Fex, J; Hoffman, DW; Rubio, JA; Zamir, N | 1 |
Christensson-Nylander, I; Nyberg, F; Ragnarsson, U; Terenius, L | 1 |
Imura, H; Inoue, T; Kabayama, Y; Kato, Y; Matsushita, N; Ohta, H; Shimatsu, A; Tojo, K; Yanaihara, N | 1 |
Barchas, JD; Böhlen, P; Esch, FS; Evans, CJ; Weber, E | 1 |
Devi, L; Goldstein, A | 2 |
Zamir, N | 1 |
Nordström, K; Nyberg, F; Terenius, L | 1 |
Akil, H; Dores, RM | 1 |
Hong, JS; Kanamatsu, T; McGinty, JF; Mitchell, CL | 1 |
Brownstein, MJ; Dawbarn, D; Emson, PC; Hunt, SP; Waters, CM; Zamir, N | 1 |
Cox, BM; Hassen, AH; Molineaux, CJ; Rosenberger, JG | 1 |
Hisamitsu, T; Okada, M | 1 |
Herkenham, M; Jacobson, AE; McLean, S; Rice, KC; Rothman, RB | 1 |
Camargo, AC; Metters, KM; Oliveira, EB; Rossier, J; Toffoletto, O | 1 |
Anticich, TG; Baumeister, AA; Hawkins, MF; Higgins, TD; Moore, LL | 1 |
McCall, LD; Simerly, RB; Watson, SJ | 1 |
Blacher, R; Kilpatrick, DL; Lahm, HW; Udenfriend, S; Wahlstrom, A | 1 |
Hayashi, K; Ikeda, Y; Imura, H; Nakao, K; Sakamoto, M; Suda, M; Yoshimasa, T | 1 |
Barchas, JD; Cone, RI; Goldstein, A; Weber, E | 1 |
Grimm, C; Herz, A; Höllt, V; Seizinger, BR | 1 |
Fischli, W; Goldstein, A; James, IF | 1 |
Herz, A; Höllt, V; Seizinger, BR | 1 |
Ikeda, Y; Imura, H; Morii, N; Nakao, K; Numa, S; Sakamoto, M; Suda, M; Yanaihara, C; Yanaihara, N; Yoshimasa, T | 2 |
Han, JS | 1 |
Bannon, MJ; Helke, CJ; Jacobowitz, DM; Kopin, IJ; Skofitsch, G; Zamir, N | 1 |
Grimm, C; Herz, A; Liebisch, DC; Seizinger, BR | 1 |
Ikeda, Y; Imura, H; Nakao, K; Numa, S; Sakamoto, M; Suda, M; Yanaihara, C; Yanaihara, N; Yoshimasa, T | 1 |
Goldstein, A; Han, JS; Xie, GX | 1 |
Akita, T; Inai, M; Kiso, Y; Kitagawa, K; Moritoki, H | 1 |
Brownstein, MJ; Palkovits, M; Weber, E; Zamir, N | 1 |
Cone, RI; Goldstein, A | 1 |
Berman, YL; Devi, LA; Juliano, L | 1 |
Nylander, I; Terenius, L; Vlaskovska, M | 1 |
Nylander, I; Silberring, J; Tan-No, K; Winter, A | 1 |
Healy, DJ; Meador-Woodruff, JH | 1 |
Madamba, SG; Moore, SD; Schweitzer, P; Siggins, GR | 1 |
Desiraju, T; Nagaraja, TN; Raju, TR; Singh, J | 1 |
Meador-Woodruff, JH; Ramsdell, CD | 1 |
Bennardini, F; Pinna, G; Pintus, G; Tadolini, B; Vaona, I; Ventura, C | 1 |
Aromataris, EC; Riederer, BM; Steele, PA | 1 |
Cairns, N; Herrera-Marschitz, M; Lubec, G; Risser, D; Schneider, C; Seidl, R; Terenius, L; You, ZB | 1 |
Chrousos, GP; Gravanis, A; Karl, M; Margioris, AN; Saviolakis, GA | 1 |
Pintus, G; Ventura, C | 1 |
Bakalkin, G; Terenius, L; Yakovleva, T | 1 |
Nylander, I; Silberring, J; Tan-No, K; Terenius, L | 1 |
Mathé, AA; Nylander, I; Stenfors, C; Tan-No, K; Terenius, L | 1 |
Kasakov, L; Nylander, I; Sandin, J; Silberring, J; Tan-No, K; Terenius, L; Winter, A | 1 |
Cheĭdo, MA; Idova, GV | 2 |
Füzesi, M; Halasy, K; Rácz, B | 1 |
Maioli, M; Ventura, C | 1 |
Gustavsson, L; Nylander, I; Ploj, K; Roman, E | 1 |
Bakalkin, G; Esashi, A; Kisara, K; Nakagawasai, O; Niijima, F; Sakurada, C; Sakurada, T; Tadano, T; Tan-No, K; Terenius, L | 1 |
Fadda, M; Maioli, M; Maninchedda, E; Ventura, C; Zinellu, E | 1 |
Maioli, M; Maninchedda, E; Ventura, C; Zinellu, E | 1 |
Bogacka, I; Kaminski, T; Okrasa, S; Przala, J; Siawrys, G | 1 |
Nylander, I; Ploj, K; Roman, E | 1 |
Bogacka, I; Kaminski, T; Okrasa, S; Przala, J; Siawrys, C | 1 |
Chen, C; Chen, Y; Liu-Chen, LY | 1 |
Bakalkin, G; Bazov, I; Hauser, KF; Ivanova, T; Khmyz, V; Krishtal, O; Lindskog, CJ; Maximyuk, O; Vukojević, V | 1 |
Berman, Y; Carr, KD; Devi, L | 2 |
Fujimura, T; Hayashi, T; Kastin, AJ; Murayama, K; Narita, M; Orito, T; Sakurada, C; Sakurada, S; Sakurada, T; Suzuki, T; Tan-no, K; Tseng, LF; Yuhki, M; Zadina, JE | 1 |
Akil, H; Goldstein, A; Mansour, A; Meng, F; Thompson, RC; Watson, SJ; Xie, GX | 1 |
Adapa, ID; Auh, JS; Berzetei-Gurske, IP; Brandt, SR; Craymer, K; Farrington, L; Haggart, D; Kennedy, JM; O'Brien, A; Polgar, WE; Rodriguez, L; Schwartz, RW; Toll, L; White, A | 1 |
77 other study(ies) available for enkephalin, leucine and rimorphin
Article | Year |
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Peptides for calling? An immunohistochemical study of the avian n. intercollicularis.
Topics: Adrenocorticotropic Hormone; Animals; Birds; Columbidae; Dynorphins; Endorphins; Enkephalin, Leucine; Female; Immune Sera; Immunohistochemistry; Male; Mesencephalon; Species Specificity; Vocalization, Animal | 1992 |
Kappa opioid agonists inhibit transmitter release from guinea pig hippocampal mossy fiber synaptosomes.
Topics: Animals; Azocines; Calcium; Dynorphins; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Ethylketocyclazocine; Glutamates; Glutamic Acid; Guinea Pigs; Hippocampus; Male; Potassium; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Synaptosomes | 1992 |
Isoforms of a dynorphin B converting enzyme isolated by column electrophoresis in agarose suspension.
Topics: Animals; Cattle; Chromatography, Gel; Chromatography, High Pressure Liquid; Cysteine Endopeptidases; Dynorphins; Electrophoresis, Agar Gel; Endorphins; Enkephalin, Leucine; Hydroxymercuribenzoates; Isoelectric Point; Isoenzymes; Kinetics; Molecular Weight; Spinal Cord | 1991 |
Studies of specificity and inhibition of human cerebrospinal fluid dynorphin converting enzyme.
Topics: Amino Acid Sequence; Cysteine Endopeptidases; Dose-Response Relationship, Drug; Dynorphins; Endorphins; Enkephalin, Leucine; Humans; Hydroxylamines; Molecular Sequence Data; Peptides; Protease Inhibitors; Substrate Specificity | 1991 |
Immunoreactive dynorphin B in sacral primary afferent fibers of the cat.
Topics: Animals; Axons; Cats; Colchicine; Dynorphins; Endorphins; Enkephalin, Leucine; Ganglia, Spinal; Histocytochemistry; Neurons, Afferent; Radioimmunoassay; Sacrum; Spinal Cord; Staining and Labeling | 1986 |
Measurement and chromatographic characterization of prodynorphin-derived peptides in the guinea-pig ileum.
Topics: Animals; Chromatography, Gel; Chromatography, High Pressure Liquid; Dynorphins; Endorphins; Enkephalins; Guinea Pigs; Ileum; Peptide Fragments; Protein Precursors; Radioimmunoassay | 1989 |
A novel bovine spinal cord endoprotease with high specificity for dynorphin B.
Topics: Amino Acid Sequence; Animals; Cations, Divalent; Cattle; Chelating Agents; Chromatography, High Pressure Liquid; Dynorphins; Electrophoresis, Polyacrylamide Gel; Endopeptidases; Endorphins; Enkephalin, Leucine; Hydrogen-Ion Concentration; Molecular Sequence Data; Molecular Weight; Protease Inhibitors; Spinal Cord; Substrate Specificity; Sulfhydryl Reagents | 1989 |
Prodynorphin peptide distribution in the forebrain of the Syrian hamster and rat: a comparative study with antisera against dynorphin A, dynorphin B, and the C-terminus of the prodynorphin precursor molecule.
Topics: Animals; Brain Chemistry; Colchicine; Cricetinae; Dynorphins; Endorphins; Enkephalins; Immune Sera; Immunoenzyme Techniques; Male; Mesocricetus; Peptide Fragments; Perfusion; Protein Precursors; Rats; Rats, Inbred Strains; Species Specificity | 1989 |
Methionine and leucine enkephalin in rat neurohypophysis: different responses to osmotic stimuli and T2 toxin.
Topics: Animals; Dynorphins; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Male; Osmosis; Oxytocin; Pituitary Gland, Posterior; Protein Precursors; Rats; Rats, Inbred Strains; Saline Solution, Hypertonic; Sesquiterpenes; T-2 Toxin; Vasopressins; Water Deprivation | 1985 |
Possible interactions between dynorphin and dopaminergic systems in rat basal ganglia and substantia nigra.
Topics: Animals; Caudate Nucleus; Corpus Striatum; Dopamine; Dynorphins; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Globus Pallidus; Haloperidol; Male; Putamen; Rats; Rats, Inbred Strains; Substantia Nigra | 1985 |
Proenkephalin and prodynorphin related neuropeptides in the cochlea.
Topics: Animals; Cochlea; Dynorphins; Endorphins; Enkephalin, Methionine; Enkephalins; Female; Guinea Pigs; Hair Cells, Auditory; Nerve Tissue Proteins; Protein Precursors | 1985 |
A general procedure for analysis of proenkephalin B derived opioid peptides.
Topics: Chromatography, Gel; Chromatography, High Pressure Liquid; Dynorphins; Endorphins; Enkephalin, Leucine; Enkephalins; Humans; Hypothalamus; Molecular Weight; Pituitary Gland; Protein Precursors | 1985 |
Stimulation by leumorphin of prolactin secretion from the pituitary in rats.
Topics: Animals; beta-Endorphin; Dynorphins; Endorphins; Enkephalins; Injections, Intraventricular; Male; Naloxone; Pituitary Gland, Anterior; Prolactin; Protein Precursors; Rats; Swine; Thyrotropin-Releasing Hormone | 1985 |
Isolation and characterization of an endogenous C-terminal fragment of the alpha-neo-endorphin/dynorphin precursor from bovine caudate nucleus.
Topics: Animals; Cattle; Caudate Nucleus; Dynorphins; Endorphins; Enkephalins; Protein Precursors; Rabbits; Radioimmunoassay | 1985 |
Neuropeptide processing by single-step cleavage: conversion of leumorphin (dynorphin B-29) to dynorphin B.
Topics: Animals; Brain; Cell Membrane; Chromatography, High Pressure Liquid; Cysteine Endopeptidases; Dynorphins; Endopeptidases; Endorphins; Enkephalins; Iodine Radioisotopes; Kinetics; Protein Precursors; Rats | 1985 |
On the origin of Leu-enkephalin and Met-enkephalin in the rat neurohypophysis.
Topics: Animals; Arginine Vasopressin; beta-Endorphin; Dynorphins; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Hypothalamus, Middle; Male; Paraventricular Hypothalamic Nucleus; Peptide Fragments; Pituitary Gland, Posterior; Protein Precursors; Rats; Rats, Inbred Strains; Rats, Inbred WKY; Sodium Glutamate | 1985 |
Endopeptidase in human cerebrospinal fluid which cleaves proenkephalin B opioid peptides at consecutive basic amino acids.
Topics: Amino Acids; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Dynorphins; Endorphins; Enkephalin, Leucine; Enkephalins; Humans; Hydrolysis; Protein Precursors; Radioimmunoassay; Serine Endopeptidases; Serine Proteinase Inhibitors | 1985 |
Steady state levels of pro-dynorphin-related end products in the striatum and substantia nigra of the adult rhesus monkey.
Topics: Animals; Chromatography, Gel; Chromatography, High Pressure Liquid; Corpus Striatum; Dynorphins; Endorphins; Enkephalins; Female; Macaca mulatta; Peptide Fragments; Protein Precursors; Radioimmunoassay; Substantia Nigra | 1985 |
Dynorphin- and enkephalin-like immunoreactivity is altered in limbic-basal ganglia regions of rat brain after repeated electroconvulsive shock.
Topics: Animals; Basal Ganglia; Brain Chemistry; Dynorphins; Electroshock; Endorphins; Enkephalin, Leucine; Enkephalins; Hippocampus; Immunologic Techniques; Male; Radioimmunoassay; Rats; Rats, Inbred F344; Time Factors; Tissue Distribution | 1986 |
Peptides derived from prodynorphin are decreased in basal ganglia of Huntington's disease brains.
Topics: Basal Ganglia; Caudate Nucleus; Dynorphins; Endorphins; Enkephalins; Globus Pallidus; Humans; Huntington Disease; Protein Precursors; Putamen; Substantia Nigra | 1986 |
Conversion of leumorphin (dynorphin B-29) to dynorphin B and dynorphin B-14 by thiol protease activity.
Topics: Adrenocorticotropic Hormone; Cysteine Endopeptidases; Dynorphins; Endopeptidases; Endorphins; Enkephalins; Hydrogen-Ion Concentration; Peptides; Protease Inhibitors; Protein Precursors; Temperature | 1986 |
Response of rat pituitary anterior lobe prodynorphin products to changes in gonadal steroid environment.
Topics: Animals; Dynorphins; Endorphins; Enkephalin, Leucine; Enkephalins; Female; Gonadal Steroid Hormones; Male; Orchiectomy; Ovariectomy; Pituitary Gland, Anterior; Protein Precursors; Rats; Testosterone | 1986 |
[Effects of opiate and opioid peptides administered intrathecally on the pain threshold and micturition reflex in rats].
Topics: Animals; Dynorphins; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Female; Injections, Spinal; Morphine; Pain; Rats; Rats, Inbred Strains; Reflex; Sensory Thresholds; Urination | 1986 |
Distribution of opiate receptor subtypes and enkephalin and dynorphin immunoreactivity in the hippocampus of squirrel, guinea pig, rat, and hamster.
Topics: Animals; Autoradiography; Cricetinae; Dynorphins; Endorphins; Enkephalins; Female; Guinea Pigs; Hippocampus; Histocytochemistry; Immunochemistry; Male; Mesocricetus; Rats; Receptors, Opioid; Sciuridae | 1987 |
Brain endo-oligopeptidase A, a putative enkephalin converting enzyme.
Topics: Animals; Bradykinin; Brain; Cattle; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Cytosol; Dynorphins; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; Metalloendopeptidases; Neurotensin; Peptide Fragments; Rats; Substrate Specificity; Sulfhydryl Reagents | 1987 |
Bilateral intranigral microinjection of morphine and opioid peptides produces antinociception in rats.
Topics: Animals; Dynorphins; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Male; Microinjections; Morphine; Naloxone; Pain; Pain Measurement; Rats; Rats, Inbred Strains; Reaction Time; Substantia Nigra | 1987 |
Distribution of opioid peptides in the preoptic region: immunohistochemical evidence for a steroid-sensitive enkephalin sexual dimorphism.
Topics: Animals; Animals, Newborn; Dynorphins; Endorphins; Enkephalin, Leucine; Enkephalins; Female; Immunohistochemistry; Male; Ovariectomy; Peptides; Preoptic Area; Rats; Rats, Inbred Strains; Sex Characteristics; Steroids | 1988 |
Rimorphin, a unique, naturally occurring [Leu]enkephalin-containing peptide found in association with dynorphin and alpha-neo-endorphin.
Topics: Amino Acid Sequence; Animals; Dynorphins; Endorphins; Enkephalin, Leucine; Hypothalamus; Pituitary Gland; Pituitary Gland, Posterior; Rats; Spinal Cord; Swine | 1982 |
Rimorphin (dynorphin B) exists together with alpha-neo-endorphin and dynorphin (dynorphin A) in human hypothalamus.
Topics: Adult; Chromatography, High Pressure Liquid; Dynorphins; Endorphins; Enkephalin, Leucine; Female; Humans; Hypothalamus; Protein Precursors | 1983 |
Regional distribution of dynorphin and neo-endorphin peptides in rat brain, spinal cord, and pituitary.
Topics: Animals; beta-Endorphin; Brain Chemistry; Chromatography, Gel; Chromatography, High Pressure Liquid; Dynorphins; Endorphins; Enkephalin, Leucine; Immune Sera; Male; Peptide Fragments; Peptides; Pituitary Gland; Protein Precursors; Radioimmunoassay; Rats; Rats, Inbred Strains; Spinal Cord; Tissue Distribution | 1983 |
Evidence for a selective processing of proenkephalin B into different opioid peptide forms in particular regions of rat brain and pituitary.
Topics: Amino Acid Sequence; Animals; beta-Endorphin; Brain; Chromatography, High Pressure Liquid; Dynorphins; Endorphins; Enkephalin, Leucine; Enkephalins; Male; Molecular Weight; Organ Specificity; Peptide Fragments; Pituitary Gland; Pituitary Gland, Posterior; Protein Precursors; Radioimmunoassay; Rats; Rats, Inbred Strains | 1984 |
Opioid receptor selectivity of dynorphin gene products.
Topics: Animals; Dynorphins; Endorphins; Enkephalin, Leucine; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Myenteric Plexus; Naloxone; Naltrexone; Peptide Fragments; Protein Precursors; Receptors, Opioid | 1984 |
Proenkephalin B (prodynorphin)-derived opioid peptides: evidence for a differential processing in lobes of the pituitary.
Topics: Animals; beta-Endorphin; Chromatography, High Pressure Liquid; Dynorphins; Endorphins; Enkephalin, Leucine; Enkephalins; Male; Molecular Weight; Peptide Fragments; Pituitary Gland; Pituitary Gland, Anterior; Pituitary Gland, Posterior; Protein Precursors; Radioimmunoassay; Rats; Rats, Inbred Strains; Tissue Distribution | 1984 |
Human leumorphin is a potent, kappa opioid receptor agonist.
Topics: Animals; Benzomorphans; Depression, Chemical; Dynorphins; Endorphins; Enkephalins; Guinea Pigs; Humans; Ileum; Male; Naloxone; Protein Precursors; Rabbits; Receptors, Opioid; Receptors, Opioid, kappa; Swine; Vas Deferens | 1984 |
[Endogenous morphine-like substances: biogenesis, release and degradation].
Topics: Animals; DNA, Recombinant; Dynorphins; Endorphins; Enkephalins; Gene Expression Regulation; Humans; In Vitro Techniques; Pituitary Gland; Protease Inhibitors; Protein Biosynthesis | 1984 |
Primate model of Parkinson's disease: alterations in multiple opioid systems in the basal ganglia.
Topics: Animals; Basal Ganglia; Dynorphins; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Female; Macaca mulatta; Male; Nucleus Accumbens; Parkinson Disease; Protein Precursors; Substantia Nigra | 1984 |
Ontogenetic development of the pro-enkephalin B (= pro-dynorphin) opioid peptide system in the rat pituitary.
Topics: Animals; Animals, Newborn; Cell Differentiation; Chromatography, High Pressure Liquid; Dynorphins; Endorphins; Enkephalin, Leucine; Enkephalins; Female; Male; Molecular Weight; Oxytocin; Peptide Fragments; Peptides; Pituitary Gland, Anterior; Pituitary Gland, Posterior; Pregnancy; Protein Precursors; Rats; Rats, Inbred Strains; Vasopressins | 1984 |
Comparison of the action of putative endogenous kappa-agonists, leumorphin and rimorphin in vitro.
Topics: Animals; Biological Assay; Dynorphins; Electric Stimulation; Endorphins; Enkephalin, Leucine; Enkephalins; Guinea Pigs; Ileum; Male; Muscle Contraction; Muscle, Smooth; Naloxone; Protein Precursors; Rabbits; Receptors, Opioid; Receptors, Opioid, kappa; Vas Deferens | 1983 |
Analgesia induced by intrathecal injection of dynorphin B in the rat.
Topics: Analgesics; Animals; Cyclazocine; Dose-Response Relationship, Drug; Drug Tolerance; Dynorphins; Endorphins; Enkephalin, Leucine; Ethylketocyclazocine; Female; Injections, Spinal; Morphine; Naloxone; Rats | 1984 |
Synthesis of a newly isolated opioid tridecapeptide, rimorphin, from pituitary using a trifluoroacetic acid-thioanisole deprotection system.
Topics: Amino Acid Sequence; Analgesics; Animals; Dynorphins; Endorphins; Enkephalin, Leucine; Guinea Pigs; In Vitro Techniques; Mice; Muscle Contraction; Muscle, Smooth | 1983 |
Leumorphin is a novel endogenous opioid peptide derived from preproenkephalin B.
Topics: Animals; Chemical Phenomena; Chemistry; Chromatography, Gel; Chromatography, High Pressure Liquid; Dynorphins; Electrophoresis, Polyacrylamide Gel; Endorphins; Enkephalin, Leucine; Enkephalins; Pituitary Gland; Protein Precursors; Radioimmunoassay; Swine | 1983 |
Distribution of immunoreactive dynorphin B in discrete areas of the rat brain and spinal cord.
Topics: Animals; Brain Chemistry; Diencephalon; Dynorphins; Endorphins; Enkephalin, Leucine; Hypothalamus; Male; Medulla Oblongata; Mesencephalon; Pituitary Gland; Pons; Radioimmunoassay; Rats; Rats, Inbred Strains; Spinal Cord; Telencephalon | 1984 |
A specific radioimmunoassay for the opioid peptide dynorphin B in neural tissues.
Topics: Animals; Brain Chemistry; Dynorphins; Endorphins; Enkephalin, Leucine; Immune Sera; Male; Pituitary Gland; Radioimmunoassay; Rats; Rats, Inbred Strains; Spinal Cord; Tissue Distribution | 1982 |
Purification and characterization of a dynorphin-processing endopeptidase.
Topics: Amino Acid Sequence; Animals; Binding Sites; Cattle; Dynorphins; Endorphins; Enkephalins; Isoelectric Point; Kinetics; Molecular Sequence Data; Molecular Weight; Peptide Fragments; Pituitary Gland; Protein Precursors; Protein Processing, Post-Translational; Serine Endopeptidases; Substrate Specificity | 1995 |
The effects of morphine treatment and morphine withdrawal on the dynorphin and enkephalin systems in Sprague-Dawley rats.
Topics: Analysis of Variance; Animals; Drug Tolerance; Dynorphins; Endorphins; Enkephalin, Leucine; Male; Morphine; Naloxone; Peptides; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome | 1995 |
Processing of prodynorphin-derived peptides in striatal extracts. Identification by electrospray ionization mass spectrometry linked to size-exclusion chromatography.
Topics: Animals; Anti-Bacterial Agents; Chromatography, Gel; Corpus Striatum; Dynorphins; Endorphins; Enkephalin, Leucine; Enkephalins; Male; Mass Spectrometry; Peptide Hydrolases; Peptides; Protein Precursors; Rats; Sensitivity and Specificity; Tissue Extracts | 1995 |
Prodynorphin-derived peptide expression in primate cortex and striatum.
Topics: Animals; Cerebral Cortex; Corpus Striatum; Dynorphins; Endorphins; Enkephalins; Macaca nemestrina; Peptide Fragments; Protein Precursors; Tissue Distribution | 1994 |
Voltage-dependent effects of opioid peptides on hippocampal CA3 pyramidal neurons in vitro.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Barium Compounds; Cadmium; Carbachol; Chlorides; Computer Simulation; Dynorphins; Electrophysiology; Endorphins; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine-2-Alanine; Enkephalins; Hippocampus; In Vitro Techniques; Male; Membrane Potentials; Models, Neurological; Naloxone; Narcotics; Neurons; Pyramidal Tracts; Pyrrolidines; Rats; Rats, Sprague-Dawley | 1994 |
Facilitation of self-stimulation of ventral tegmentum by microinjection of opioid receptor subtype agonists.
Topics: Analgesics; Animals; Brain Mapping; Dose-Response Relationship, Drug; Dynorphins; Electric Stimulation; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Methionine; Enkephalins; Hypothalamic Area, Lateral; Male; Medial Forebrain Bundle; Motivation; Naloxone; Neural Pathways; Rats; Rats, Wistar; Receptors, Opioid; Self Stimulation; Substantia Nigra; Tegmentum Mesencephali; Ventral Tegmental Area | 1994 |
Expression of prodynorphin-derived peptides and mRNA in guinea-pig cortex.
Topics: Animals; Blotting, Northern; Cerebral Cortex; Corpus Striatum; Dynorphins; Endorphins; Enkephalins; Guinea Pigs; Male; Organ Specificity; Peptide Fragments; Protein Precursors; Radioimmunoassay; RNA, Messenger | 1993 |
Phorbol ester regulation of opioid peptide gene expression in myocardial cells. Role of nuclear protein kinase.
Topics: Alkaloids; Animals; Cell Nucleus; Cells, Cultured; Dose-Response Relationship, Drug; Dynorphins; Endorphins; Enkephalins; Enzyme Inhibitors; Gene Expression; Heart Ventricles; Isoenzymes; Kinetics; Male; Myocardium; Phorbol Esters; Protein Kinase C; Protein Precursors; Rats; Rats, Wistar; Staurosporine; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1995 |
Endogenous opioid peptides in parasympathetic, sympathetic and sensory nerves in the guinea-pig heart.
Topics: Adrenergic Fibers; Animals; Antibody Specificity; Axons; beta-Endorphin; Dynorphins; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; Female; Ganglia, Autonomic; Guinea Pigs; Heart; Immunohistochemistry; Male; Neurons, Afferent; Opioid Peptides; Parasympathetic Fibers, Postganglionic; Protein Precursors | 1996 |
Endogenous opioids in frontal cortex of patients with Down syndrome.
Topics: Aged; Alzheimer Disease; Down Syndrome; Dynorphins; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; Female; Frontal Lobe; Gene Expression Regulation; Humans; Male; Middle Aged; Protein Precursors; Radioimmunoassay | 1996 |
The PC12 rat pheochromocytoma cell line expresses the prodynorphin gene and secretes the 8 kDa dynorphin product.
Topics: Adrenal Medulla; Animals; Chromatography, Affinity; Chromatography, High Pressure Liquid; Dynorphins; Endorphins; Enkephalins; Gene Expression; PC12 Cells; Pheochromocytoma; Pituitary Gland; Polymerase Chain Reaction; Protein Precursors; Rats; Sequence Analysis | 1996 |
Opioid peptide gene expression in the primary hereditary cardiomyopathy of the Syrian hamster. III. Autocrine stimulation of prodynorphin gene expression by dynorphin B.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Calcium; Cardiomyopathy, Hypertrophic; Cell Compartmentation; Cell Nucleus; Cricetinae; Cytosol; Dynorphins; Endorphins; Enkephalins; Enzyme Inhibitors; Gene Expression; Mesocricetus; Myocardium; Protein Kinase C; Protein Precursors; Pyrrolidines; Receptors, Opioid, kappa; Ryanodine; Sarcoplasmic Reticulum | 1997 |
The Leu-enkephalin-encoding sequence DNA-binding factor (LEF) is the transcription factor YY1.
Topics: Animals; Binding Sites; Cell Nucleus; DNA; DNA-Binding Proteins; Dynorphins; Endorphins; Enkephalin, Leucine; Erythroid-Specific DNA-Binding Factors; Molecular Weight; Oligodeoxyribonucleotides; Protein Conformation; Rats; Rats, Sprague-Dawley; Transcription Factors; YY1 Transcription Factor | 1997 |
Levels of dynorphin peptides in the central nervous system and pituitary gland of the spontaneously hypertensive rat.
Topics: Animals; Biomarkers; Brain; Dynorphins; Endorphins; Enkephalins; Hypertension; Immunohistochemistry; Lumbosacral Region; Male; Pituitary Gland; Protein Precursors; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Spinal Cord | 1997 |
A comparison between microwave irradiation and decapitation: basal levels of dynorphin and enkephalin and the effect of chronic morphine treatment on dynorphin peptides.
Topics: Animals; Brain Chemistry; Decerebrate State; Dynorphins; Endorphins; Enkephalins; Injections, Subcutaneous; Male; Microwaves; Morphine; Opioid Peptides; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome | 1997 |
Differential metabolism of dynorphins in substantia nigra, striatum, and hippocampus.
Topics: Amino Acid Sequence; Animals; Chromatography, High Pressure Liquid; Corpus Striatum; Dynorphins; Endorphins; Enkephalin, Leucine; Hippocampus; Male; Mass Spectrometry; Protein Precursors; Rats; Substantia Nigra; Tissue Distribution | 1997 |
[Effect of opioid peptides on immunomodulation].
Topics: Animals; Cyproheptadine; Dopamine D2 Receptor Antagonists; Dynorphins; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Haloperidol; Male; Mice; Mice, Inbred CBA; Neuroimmunomodulation; Pituitary Gland; Receptor, Serotonin, 5-HT2A; Receptors, Dopamine D2; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Receptors, Serotonin; Spleen | 1998 |
The hippocampal opioidergic system: a comparative immunocytochemical study in four rodents.
Topics: Animals; Cricetinae; Dynorphins; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Female; Guinea Pigs; Hippocampus; Immunohistochemistry; Male; Mesocricetus; Mice; Nerve Fibers; Neurons; Pyramidal Cells; Rats; Species Specificity | 1998 |
Opioid peptide gene expression primes cardiogenesis in embryonal pluripotent stem cells.
Topics: Animals; Autocrine Communication; Cell Differentiation; Dimethyl Sulfoxide; DNA-Binding Proteins; Dynorphins; Endorphins; Enkephalins; Fetal Heart; Fetal Proteins; GATA4 Transcription Factor; Gene Expression Regulation, Developmental; Homeobox Protein Nkx-2.5; Homeodomain Proteins; Mice; Oligonucleotides, Antisense; Opioid Peptides; Protein Precursors; Recombinant Fusion Proteins; RNA, Messenger; Stem Cells; Thionucleotides; Transcription Factors; Transfection; Xenopus Proteins; Zinc Fingers | 2000 |
Basal levels and alcohol-induced changes in nociceptin/orphanin FQ, dynorphin, and enkephalin levels in C57BL/6J mice.
Topics: Alcohol Drinking; Alcohol-Induced Disorders, Nervous System; Animals; Brain; Brain Chemistry; Drug Administration Schedule; Dynorphins; Endorphins; Enkephalin, Methionine; Enkephalins; Ethanol; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Nociceptin; Opioid Peptides; Pituitary Gland; Self Administration | 2000 |
Intrathecally administered big dynorphin, a prodynorphin-derived peptide, produces nociceptive behavior through an N-methyl-D-aspartate receptor mechanism.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Analgesics, Opioid; Animals; Behavior, Animal; Dizocilpine Maleate; Dynorphins; Endorphins; Enkephalins; Excitatory Amino Acid Antagonists; Injections, Spinal; Kynurenic Acid; Male; Mice; Morphine; Neurokinin A; Nociceptors; Peptide Fragments; Piperidines; Protein Precursors; Receptors, N-Methyl-D-Aspartate; Receptors, Tachykinin; Substance P | 2002 |
Protein kinase C signaling transduces endorphin-primed cardiogenesis in GTR1 embryonic stem cells.
Topics: Animals; Cell Differentiation; Cell Line; Cell Nucleus; Dynorphins; Embryo, Mammalian; Embryo, Nonmammalian; Endorphins; Enkephalins; Enzyme Inhibitors; Gene Expression Regulation, Developmental; Heart; Isoenzymes; Myocytes, Cardiac; Myosin Heavy Chains; Narcotic Antagonists; Protein Kinase C; Protein Precursors; Receptors, Opioid, kappa; RNA, Messenger; Signal Transduction; Stem Cells | 2003 |
Dynorphin B is an agonist of nuclear opioid receptors coupling nuclear protein kinase C activation to the transcription of cardiogenic genes in GTR1 embryonic stem cells.
Topics: Animals; Cell Differentiation; Cell Line; Cell Lineage; Cell Nucleus; DNA-Binding Proteins; Dynorphins; Embryo, Mammalian; Embryo, Nonmammalian; Endorphins; Enkephalins; Enzyme Activation; GATA4 Transcription Factor; Gene Expression Regulation, Developmental; Heart; Homeobox Protein Nkx-2.5; Homeodomain Proteins; Myocytes, Cardiac; Protein Kinase C; Protein Precursors; Receptors, Opioid; RNA, Messenger; Signal Transduction; Stem Cells; Transcription Factors; Transcriptional Activation; Xenopus Proteins | 2003 |
The regulation of steroidogenesis by opioid peptides in porcine theca cells.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; beta-Endorphin; Cells, Cultured; D-Ala(2),MePhe(4),Met(0)-ol-enkephalin; Dynorphins; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Methionine; Estradiol; Female; Opioid Peptides; Progesterone; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Steroids; Swine; Testosterone; Theca Cells | 2003 |
Long-term effects of short and long periods of maternal separation on brain opioid peptide levels in male Wistar rats.
Topics: Animals; Animals, Newborn; Behavior, Animal; Body Weight; Brain; Corticosterone; Dynorphins; Endorphins; Enkephalin, Methionine; Enkephalins; Female; Male; Maternal Deprivation; Opioid Peptides; Pituitary Gland; Protein Precursors; Radioimmunoassay; Rats; Rats, Wistar; Time Factors; Ultrasonics | 2003 |
The influence of opioid peptides on steroidogenesis in porcine granulosa cells.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; beta-Endorphin; D-Ala(2),MePhe(4),Met(0)-ol-enkephalin; Dose-Response Relationship, Drug; Dynorphins; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Female; Granulosa Cells; Luteinizing Hormone; Opioid Peptides; Ovarian Follicle; Swine | 2004 |
Dynorphin peptides differentially regulate the human kappa opioid receptor.
Topics: Animals; Binding, Competitive; Blotting, Western; CHO Cells; Cricetinae; Cricetulus; Down-Regulation; Dynorphins; Electrophoresis, Polyacrylamide Gel; Endorphins; Enkephalins; Flow Cytometry; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Ligands; Peptides; Protease Inhibitors; Protein Precursors; Receptors, Opioid, kappa | 2007 |
Immune response of submissive and aggressive mice under conditions of opioid receptor activation.
Topics: Aggression; Animals; Dynorphins; Endorphins; Enkephalin, Leucine; Immunomodulation; Male; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu | 2009 |
Plasma membrane poration by opioid neuropeptides: a possible mechanism of pathological signal transduction.
Topics: Analgesics, Opioid; Animals; Cell Membrane; Dynorphins; Endorphins; Enkephalins; Humans; Ligands; Microscopy, Confocal; Neuropeptides; Opioid Peptides; PC12 Cells; Protein Precursors; Rats; Signal Transduction | 2015 |
Effects of streptozotocin-induced diabetes on prodynorphin-derived peptides in rat brain regions.
Topics: Animals; Brain; Diabetes Mellitus, Experimental; Dynorphins; Enkephalins; Hypothalamic Hormones; Male; Peptide Fragments; Protein Precursors; Rats; Rats, Sprague-Dawley | 1995 |
Effects of chronic food restriction on prodynorphin-derived peptides in rat brain regions.
Topics: Animals; Diet; Dynorphins; Enkephalins; Hypothalamic Hormones; Male; Neuropeptides; Peptide Fragments; Protein Precursors; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Time Factors | 1994 |
Differential antinociceptive effects induced by intrathecally administered endomorphin-1 and endomorphin-2 in the mouse.
Topics: Analgesics; Animals; Benzylidene Compounds; Dose-Response Relationship, Drug; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Methionine; Immune Sera; Injections, Spinal; Injections, Subcutaneous; Male; Mice; Naloxone; Naltrexone; Narcotic Antagonists; Oligopeptides; Pain; Pain Measurement; Pain Threshold; Peptide Fragments; Time Factors | 2001 |
Cloning and pharmacological characterization of a rat kappa opioid receptor.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Amino Acid Sequence; Analgesics; Animals; Benzeneacetamides; Cell Line; Cell Membrane; Cloning, Molecular; Corpus Striatum; Cyclic AMP; DNA Primers; DNA, Complementary; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Gene Library; In Situ Hybridization; Inositol 1,4,5-Trisphosphate; Kinetics; Ligands; Molecular Sequence Data; Pyrrolidines; Rats; Receptors, Opioid, kappa; Restriction Mapping; RNA, Messenger; Transfection | 1993 |
Standard binding and functional assays related to medications development division testing for potential cocaine and opiate narcotic treatment medications.
Topics: Animals; Aorta, Thoracic; Cocaine; Cyclic AMP; Electric Stimulation; Guinea Pigs; Humans; Ileum; In Vitro Techniques; Male; Mice; Muscle, Smooth; Opioid-Related Disorders; Rats; Receptors, Dopamine; Receptors, Opioid; Receptors, Serotonin; Substance-Related Disorders | 1998 |