enkephalin, leucine and oxymorphone

enkephalin, leucine has been researched along with oxymorphone in 26 studies

Research

Studies (26)

Timeframe	Studies, this research(%)	All Research%
pre-1990	17 (65.38)	18.7374
1990's	6 (23.08)	18.2507
2000's	2 (7.69)	29.6817
2010's	1 (3.85)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Larson, DL; Lemieux, C; Nguyen, TM; Portoghese, PS; Ronsisvalle, G; Schiller, PW; Takemori, AE	1
Lipkowski, AW; Portoghese, PS; Tam, SW	1
Berkowitz, DS; Burt, SK; Loew, GH	1
Costa, EM; Hoffmann, BB; Loew, GH	1
Bykov, V; Holaday, JW; Jacobson, AE; Long, JB; Rice, KC; Rothman, RB	1
Goodman, RR; Hahn, EF; Nishimura, S; Pasternak, GW	1
Hahn, EF; Itzhak, Y; Johnson, N; Nishimura, S; Pasternak, GW	1
Galetta, S; Hahn, EF; Nishimura, S; Pasternak, GW	1
Bodnar, RJ; Burks, TF; Clark, JE; Hahn, EF; Pasternak, GW; Williams, CL	1
Liang, CS; Sakamoto, S	1
Bowen, WD; Herkenham, M; Jacobson, AE; Pert, CB; Rice, KC; Rothman, RB	1
Bowen, WD; Bykov, V; Jacobson, AE; Kooper, GN; Rice, KC; Rothman, RB	1
Giles, TD; Given, MB; Sander, GE	1
Bowen, WD; Burke, TR; Bykov, V; Jacobson, AE; Pert, CB; Rice, KC; Rothman, RB; Schumacher, UK	1
Day, AR; Freer, RJ; Liao, CS	1
Chang, KJ; Cuatrecasas, P; Hazum, E; Leighton, HJ; Lever, OW	1
Giles, T; Merz, H; Sander, G	1
Burke, TR; Danks, JA; Jacobson, AE; Pert, CB; Rice, KC; Rothman, RB	1
Gioannini, TL; Hiller, JM; Itzhak, Y; Simon, EJ	1
Borsodi, A; Búzás, B; Friedmann, T; Fürst, Z; Schmidhammer, H	1
Gao, P	1
DiGiacomo, B; Larson, DL; Ohkawa, S; Portoghese, PS; Takemori, AE	1
Borsodi, A; Hosztafi, S; Nevin, ST; Rónai, AZ; Spetea, M; Tóth, G	1
Salvadori, S; Temussi, PA	1
Virk, MS; Williams, JT	1
Ambrosio, C; Casella, I; Costa, T; Grò, C; Molinari, P; Riitano, D; Sbraccia, M; Vezzi, V	1

Reviews

2 review(s) available for enkephalin, leucine and oxymorphone

Article	Year
Structure-activity studies of narcotic agonists and antagonists from quantum chemical calculations. NIDA research monograph, 1978, Issue:22 Topics: Animals; Chemical Phenomena; Chemistry, Physical; Enkephalins; In Vitro Techniques; Methadone; Models, Molecular; Molecular Conformation; Nalorphine; Narcotic Antagonists; Narcotics; Oxymorphone; Piperidines; Quantum Theory; Receptors, Opioid; Structure-Activity Relationship; Thermodynamics	1978
Antagonism in opioid peptides: the role of conformation. Current topics in medicinal chemistry, 2004, Volume: 4, Issue:1 Topics: Animals; Binding Sites; Drug Design; Enkephalin, Leucine; Humans; Morphine Derivatives; Narcotic Antagonists; Opioid Peptides; Oxymorphone; Peptides, Cyclic; Protein Conformation; Protein Structure, Tertiary; Receptors, Opioid; Receptors, Opioid, delta; Spiro Compounds; Structure-Activity Relationship	2004

Article

Year

Structure-activity studies of narcotic agonists and antagonists from quantum chemical calculations.

NIDA research monograph, 1978, Issue:22

Topics: Animals; Chemical Phenomena; Chemistry, Physical; Enkephalins; In Vitro Techniques; Methadone; Models, Molecular; Molecular Conformation; Nalorphine; Narcotic Antagonists; Narcotics; Oxymorphone; Piperidines; Quantum Theory; Receptors, Opioid; Structure-Activity Relationship; Thermodynamics

1978

Antagonism in opioid peptides: the role of conformation.

Current topics in medicinal chemistry, 2004, Volume: 4, Issue:1

Topics: Animals; Binding Sites; Drug Design; Enkephalin, Leucine; Humans; Morphine Derivatives; Narcotic Antagonists; Opioid Peptides; Oxymorphone; Peptides, Cyclic; Protein Conformation; Protein Structure, Tertiary; Receptors, Opioid; Receptors, Opioid, delta; Spiro Compounds; Structure-Activity Relationship

2004

Other Studies

24 other study(ies) available for enkephalin, leucine and oxymorphone

Article	Year
Hybrid bivalent ligands with opiate and enkephalin pharmacophores. Journal of medicinal chemistry, 1987, Volume: 30, Issue:11 Topics: Analgesics; Animals; Enkephalins; Guinea Pigs; Hydromorphone; Ligands; Male; Mice; Muscle, Smooth; Naloxone; Oxymorphone; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu	1987
Peptides as receptor selectivity modulators of opiate pharmacophores. Journal of medicinal chemistry, 1986, Volume: 29, Issue:7 Topics: Animals; Dynorphins; Endorphins; Enkephalin, Leucine; Guinea Pigs; Indicators and Reagents; Kinetics; Oligopeptides; Receptors, Opioid; Structure-Activity Relationship	1986
Opioid agonists binding and responses in SH-SY5Y cells. Life sciences, 1992, Volume: 50, Issue:1 Topics: Alprostadil; Analgesics; Cyclic AMP; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Fentanyl; GTP Phosphohydrolases; Humans; Meperidine; Morphinans; Naloxone; Narcotics; Oxymorphone; Receptors, Opioid; Receptors, Opioid, mu; Tumor Cells, Cultured	1992
Pretreatment of rats with the irreversible mu-receptor antagonist, beta-FNA, fails to prevent naltrexone-induced upregulation of mu-opioid receptors. Neuropharmacology, 1990, Volume: 29, Issue:9 Topics: Animals; Brain; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine-2-Alanine; Enkephalins; In Vitro Techniques; Isothiocyanates; Kinetics; Naltrexone; Narcotic Antagonists; Oxymorphone; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, mu; Thiocyanates; Up-Regulation	1990
Irreversible opiate agonists and antagonists. II. Evidence against a bivalent mechanism of action for opiate azines and diacylhydrazones. The Journal of pharmacology and experimental therapeutics, 1985, Volume: 235, Issue:3 Topics: Animals; Binding, Competitive; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Hydromorphone; In Vitro Techniques; Male; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Oxymorphone; Rats; Rats, Inbred Strains; Receptors, Opioid; Structure-Activity Relationship	1985
Irreversible opiate agonists and antagonists. III. Phenylhydrazone derivatives of naloxone and oxymorphone. The Journal of pharmacology and experimental therapeutics, 1985, Volume: 235, Issue:3 Topics: Albumins; Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Hydrazones; Hydromorphone; In Vitro Techniques; Male; Naloxone; Narcotic Antagonists; Narcotics; Oxymorphone; Rats; Rats, Inbred Strains; Receptors, Opioid; Structure-Activity Relationship; Tritium	1985
Oxymorphone-naltrexonazine, a mixed opiate agonist-antagonist. Life sciences, 1987, Aug-10, Volume: 41, Issue:6 Topics: Analgesia; Animals; Binding, Competitive; Brain; Dihydromorphine; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Hydromorphone; Male; Mice; Mice, Inbred ICR; Naltrexone; Oxymorphone; Rats; Rats, Inbred Strains; Receptors, Opioid; Sodium	1987
Irreversible opiate agonists and antagonists. IV. Analgesic actions of 14-hydroxydihydromorphinone hydrazones. The Journal of pharmacology and experimental therapeutics, 1988, Volume: 245, Issue:1 Topics: Analgesia; Animals; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Hydrazones; Hydromorphone; Male; Mice; Naloxone; Oxymorphone; Receptors, Opioid; Time Factors	1988
Opiate receptor inhibition improves the blunted baroreflex function in conscious dogs with right-sided congestive heart failure. Circulation, 1989, Volume: 80, Issue:4 Topics: Animals; Blood Pressure; Consciousness; Dogs; Electrocardiography; Enkephalin, Leucine; Heart Failure; Naloxone; Narcotic Antagonists; Oxymorphone; Phenylephrine; Pressoreceptors; Receptors, Opioid; Reflex	1989
A quantitative study of [3H]D-Ala2-D-Leu5-enkephalin binding to rat brain membranes. Evidence that oxymorphone is a noncompetitive inhibitor of the lower affinity delta-binding site. Molecular pharmacology, 1985, Volume: 27, Issue:3 Topics: Animals; Autoradiography; Brain; Chlorides; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Guanosine Triphosphate; Hydromorphone; Male; Manganese; Manganese Compounds; Mathematics; Membranes; Oligopeptides; Oxymorphone; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Sodium Chloride	1985
Tritiated-6-beta-fluoro-6-desoxy-oxymorphone ([3H]FOXY): a new ligand and photoaffinity probe for the mu opioid receptors. Neuropeptides, 1988, Volume: 11, Issue:1 Topics: Affinity Labels; Animals; Brain; Chlorides; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; In Vitro Techniques; Male; Manganese; Manganese Compounds; Membranes; Oxymorphone; Photochemistry; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, mu; Tritium	1988
Non-opiate and peripheral-opiate cardiovascular effects of morphine in conscious dogs. Life sciences, 1986, Apr-07, Volume: 38, Issue:14 Topics: Animals; Blood Pressure; Cardiovascular Physiological Phenomena; Cardiovascular System; Dogs; Enkephalin, Leucine; Female; Heart Rate; Kinetics; Male; Morphine; Naloxone; Oxymorphone	1986
Preparation of rat brain membranes greatly enriched with either type-I-delta or type-II-delta opiate binding sites using site directed alkylating agents: evidence for a two-site allosteric model. Neuropeptides, 1984, Volume: 4, Issue:3 Topics: Alkylating Agents; Allosteric Regulation; Animals; Brain; Cell Membrane; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Fentanyl; Isothiocyanates; Kinetics; Male; Oxymorphone; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Thiocyanates	1984
Evidence for a single opioid receptor type on the field stimulated rat vas deferens. Life sciences, 1981, Dec-21, Volume: 29, Issue:25 Topics: Animals; Benzimidazoles; beta-Endorphin; Dose-Response Relationship, Drug; Electric Stimulation; Endorphins; Enkephalins; Etorphine; Fentanyl; Male; Morphine; Oxymorphone; Rats; Rats, Inbred Strains; Receptors, Opioid; Sufentanil; Vas Deferens	1981
Increased biological activity of dimers of oxymorphone and enkephalin: possible role of receptor crosslinking. Biochemical and biophysical research communications, 1982, Jan-15, Volume: 104, Issue:1 Topics: Animals; Binding, Competitive; Biological Assay; Brain; Cell Membrane; Chemical Phenomena; Chemistry; Endorphins; Enkephalins; Guinea Pigs; Hydromorphone; Ileum; Kinetics; Muscle Contraction; Oxymorphone; Receptors, Opioid; Structure-Activity Relationship	1982
Quaternary opiate antagonists lower blood pressure and inhibit leucine-enkephalin responses. European journal of pharmacology, 1983, Nov-25, Volume: 95, Issue:3-4 Topics: Animals; Blood Pressure; Dogs; Dose-Response Relationship, Drug; Enkephalin, Leucine; Heart Rate; Hydromorphone; Naloxone; Naltrexone; Oxymorphone; Quaternary Ammonium Compounds	1983
Tritiated-6-beta-fluoro-6-desoxy-oxymorphone: a highly selective ligand for the opiate mu receptor whose binding is characterized by low nonspecific binding. Neuropeptides, 1984, Volume: 4, Issue:4 Topics: Animals; Benzomorphans; Brain; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Fentanyl; Hydromorphone; Isothiocyanates; Kinetics; Oxymorphone; Rats; Receptors, Opioid; Receptors, Opioid, mu; Thiocyanates; Tomography, Emission-Computed	1984
Effect of digitonin on the binding of opiate agonists and antagonists to membrane-bound and soluble opioid binding sites. Brain research, 1984, Jan-23, Volume: 291, Issue:2 Topics: Animals; Brain; Bufo marinus; Digitonin; Diprenorphine; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Etorphine; Male; Naloxone; Oxymorphone; Rats; Rats, Inbred Strains; Receptors, Opioid; Species Specificity	1984
Highly potent novel opioid receptor agonist in the 14-alkoxymetopon series. European journal of pharmacology, 1993, May-19, Volume: 236, Issue:2 Topics: Analgesics; Animals; Behavior, Animal; Binding Sites; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Female; Guinea Pigs; Male; Mice; Morphine Derivatives; Naloxone; Oxymorphone; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Species Specificity; Substance-Related Disorders	1993
Comparison of cyclic delta-opioid peptides with non-peptide delta-agonist spiroindanyloxymorphone (SIOM) using the message-address concept: a molecular modeling study. Journal of computer-aided molecular design, 1996, Volume: 10, Issue:4 Topics: Drug Design; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Ligands; Magnetic Resonance Spectroscopy; Models, Molecular; Naltrexone; Narcotic Antagonists; Oxymorphone; Peptides, Cyclic; Protein Binding; Protein Conformation; Receptors, Opioid, delta; Spiro Compounds; Structure-Activity Relationship	1996
7-Spiroindanyl derivatives of naltrexone and oxymorphone as selective ligands for delta opioid receptors. Journal of medicinal chemistry, 1997, May-23, Volume: 40, Issue:11 Topics: Analgesia; Analgesics; Animals; Brain; Cell Membrane; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Guinea Pigs; Ileum; Ligands; Male; Mice; Mice, Inbred ICR; Molecular Structure; Muscle, Smooth; Naltrexone; Oxymorphone; Receptors, Opioid, delta; Spiro Compounds; Vas Deferens	1997
Affinity profiles of novel delta-receptor selective benzofuran derivatives of non-peptide opioids. Neurochemical research, 1998, Volume: 23, Issue:9 Topics: Animals; Benzeneacetamides; Benzofurans; Binding, Competitive; Brain; Cell Membrane; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Naloxone; Naltrexone; Oligopeptides; Oxycodone; Oxymorphone; Pyrrolidines; Radioligand Assay; Rats; Rats, Wistar; Receptors, Opioid, delta; Receptors, Opioid, mu; Tritium	1998
Agonist-specific regulation of mu-opioid receptor desensitization and recovery from desensitization. Molecular pharmacology, 2008, Volume: 73, Issue:4 Topics: Analgesics, Opioid; Animals; Down-Regulation; Electrophysiology; Enkephalins; Etorphine; Fentanyl; In Vitro Techniques; Male; Naltrexone; Oxymorphone; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu	2008
Morphine-like opiates selectively antagonize receptor-arrestin interactions. The Journal of biological chemistry, 2010, Apr-23, Volume: 285, Issue:17 Topics: Arrestins; beta-Arrestin 2; beta-Arrestins; Cell Line, Tumor; Cell Membrane; Enkephalins; GTP-Binding Protein alpha Subunits; Humans; Narcotics; Oxymorphone; Pertussis Toxin; Receptors, Opioid, delta; Receptors, Opioid, mu	2010