enkephalin, leucine has been researched along with oxidopamine in 151 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 25 (16.56) | 18.7374 |
| 1990's | 66 (43.71) | 18.2507 |
| 2000's | 48 (31.79) | 29.6817 |
| 2010's | 12 (7.95) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pollack, AE; Wooten, GF | 2 |
| Angulo, JA; Cadet, JL; Zhu, SM | 2 |
| Agnati, LF; Carani, C; Cintra, A; Fuxe, K; Li, XM; Merlo Pich, E; O'Connor, WT; Tanganelli, S; Tinner, B; Von Euler, G | 1 |
| De Ceballos, ML; Jenner, P; Marsden, CD; Rose, S; Taylor, MD | 1 |
| Björklund, A; Campbell, K; Wictorin, K | 1 |
| Docter, GJ; Voorn, P | 1 |
| Biswas, S; Chowdrey, HS; Harbuz, MS; Jessop, DS; Lightman, SL | 1 |
| Calenco-Choukroun, G; Daugé, V; Gacel, G; Roques, BP | 1 |
| Alberch, J; Arenas, E; Marsal, J | 1 |
| Arbuthnott, GW; Hood, SH; Ingham, CA | 1 |
| Ida, G | 1 |
| Chase, TN; Engber, TM; Gerfen, CR; Kuo, S; Susel, Z | 1 |
| Kameyama, T; Katoh, A; Nabeshima, T | 1 |
| Alberch, J; Arenas, E; Marsal, J; Pérez-Navarro, E; Solsona, C | 1 |
| Arluison, M; Bourgoin, S; Boyer, PA; Quignon, M; Vankova, M | 1 |
| Hong, JS; Jiang, HK; McGinty, JF | 1 |
| Hong, JS; Hudson, PM; Jiang, HK; Li, SJ; Nanry, K; Owyang, V; Stachowiak, MS; Tilson, HA | 1 |
| Dilts, RP; Kalivas, PW | 2 |
| Akil, H; Bunzow, J; Camp, DM; Civelli, O; Mansour, A; Meador-Woodruff, JH; Robinson, TE; Van Tol, H; Watson, SJ | 1 |
| George, SR; Haas, DA; Roldan, L | 1 |
| Angulo, JA; Cadet, JL; McEwen, BS | 1 |
| Calenco-Choukroun, G; Daugé, V; Féger, J; Roques, BP | 1 |
| Hohmann, AG; Matsumoto, RR; Thompson, LA; Walker, JM | 1 |
| Groenewegen, HJ; Roest, G; Voorn, P | 1 |
| Archelos, J; Lang, RE; Reinecke, M; Xiang, JZ | 1 |
| Feuerstein, C; Fourrier, O; Julien, JF; Mallet, J; Rataboul, P; Vernier, P | 1 |
| Burgunder, JM; Young, WS | 1 |
| Koob, GF; Tempel, A; Unterwald, EM; Zukin, RS | 1 |
| Herz, A; Höllt, V; Morris, BJ | 1 |
| Brinsfield, KH; Matsumoto, RR; Patrick, RL; Walker, JM | 1 |
| Di Chiara, G; Morelli, M | 1 |
| Chen, SD; Pan, GB; Xu, DL; Yu, WC | 1 |
| Corti, V; Ledda, F; Mantelli, L | 1 |
| Huidobro-Toro, JP; Llona, I; Stewart, J; Vavrek, R | 1 |
| Breese, GR; Hong, JS; Krause, JE; Mueller, RA; Napier, TC; Sivam, SP | 1 |
| Su, YY; Watt, CB | 1 |
| Breese, GR; Hong, JS; Mueller, RA; Napier, TC; Sivam, SP | 1 |
| Abrous, N; Dulluc, J; Herman, JP; Le Moal, M; Vigny, A | 1 |
| Pan, HS; Penney, JB; Young, AB | 1 |
| Angulo, JA; Burkhart, BA; Christoph, GR; Davis, LG | 1 |
| Antkiewicz-Michaluk, L; Marona-Lewicka, D; Michaluk, J; Rokosz-Pelc, A; Vetulani, J | 1 |
| Cavicchini, E; Ferri, S; Murari, G; Romualdi, P; Speroni, E | 1 |
| Costa, E; Mocchetti, I; Naranjo, JR | 1 |
| Costentin, J; Giros, B; Michael-Titus, A; Preterre, P | 1 |
| Auffray, C; Bloch, B; Fellmann, D; Normand, E; Onteniente, B; Piatier-Tonneau, D; Popovici, T | 1 |
| Charnay, Y; Dray, F; Dubois, PM; Leger, L | 1 |
| Archelos, J; Lang, RE; Xiang, JZ | 1 |
| Chesselet, MF; Ciaramitaro, VM; Delfs, JM; Parry, TJ | 1 |
| Docter, GJ; Jongen-Rêlo, AL; Jonker, AJ; Voorn, P | 1 |
| Crowley, WR; Gerfen, CR; Kitai, ST; Nisenbaum, LK | 1 |
| Nishiyama, N; Schwartz, JP | 1 |
| Gerfen, CR; Kitai, ST; Nisenbaum, LK | 1 |
| Jenner, P; Jolkkonen, J; Marsden, CD; Zeng, BY | 1 |
| Besson, MJ; Mavridis, M; Rogard, M | 1 |
| Schiffmann, SN; Vanderhaeghen, JJ | 1 |
| Chan, J; Pickel, VM; Pierce, JP | 1 |
| Soghomonian, JJ | 2 |
| Gozariu, L; Gozariu, MS; Orbai, P; Sandor, V; Schmidt-Gayk, H | 1 |
| Björklund, A; Campbell, K | 1 |
| Björklund, A; Campbell, K; Lindsay, RM; Sauer, H; Wiegand, SJ | 1 |
| Landis, SC; Tyrrell, S | 1 |
| Burke, RE; Franklin, SO; Inturrisi, CE; Jones, SB; Zhu, YS | 1 |
| Mitsuo, K; Nishiyama, N; Schwartz, JP; Sheng, JG; Shirabe, S | 1 |
| Björklund, A; Campbell, K; Cenci, MA | 1 |
| Chritin, M; Feuerstein, C; Savasta, M | 1 |
| Broide, RS; Leslie, FM; Loughlin, SE; Smith, JA | 1 |
| Abrous, DN; Bal, A; Chritin, M; Feuerstein, C; Herman, JP; Le Moal, M; Mennicken, F; Savasta, M | 1 |
| Docter, GJ; Groenewegen, HJ; Melchers, BP; Roeling, TA; Voorn, P; Wolters, EC | 1 |
| Laprade, N; Radja, F; Reader, TA; Soghomonian, JJ | 1 |
| Crowley, WR; Kitai, ST; Nisenbaum, LK | 1 |
| Granata, R; Jenner, P; Jolkkonen, J; Marsden, CD; Wenning, GK | 1 |
| Kameyama, T; Toyoshi, T; Ukai, M | 1 |
| Jenner, P; Marsden, CD; Zeng, BY | 1 |
| Hajji, MD; Kerkerian-le Goff, L; Salin, P | 1 |
| Brotchie, JM; Duty, S | 1 |
| Dziewczapolski, G; Gershanik, OS; Nieoullon, A; Raisman-Vozari, R; Salin, P | 1 |
| Arbuthnott, GW; Baldock, RA; Hood, SH; Ingham, CA; Mijnster, MJ | 1 |
| Gerendai, I | 1 |
| Brotchie, JM; Crossman, AR; Duty, S; Henry, B | 1 |
| Churchill, L; Kalivas, PW; Klitenick, MA | 1 |
| Björklund, A; Cenci, MA; Lee, CS | 1 |
| Brotchie, JM; Crossman, AR; Henry, B | 1 |
| Billings, LM; Marshall, JF; Schuller, JJ | 1 |
| Laprade, N; Soghomonian, JJ | 1 |
| Caruncho, HJ; Labandeira-Garcia, JL; Liste, I; Rodriguez-Pallares, J | 1 |
| Guerra, MJ; Labandeira-Garcia, JL; Lopez-Martin, E; Rozas, G | 1 |
| Basura, GJ; Walker, PD | 3 |
| Guerra, MJ; Labandeira-Garcia, JL; Liste, I; Muñoz, A | 1 |
| Berrendero, F; de Yebenes, JG; Fernández-Ruiz, JJ; Manzanares, J; Pérez-Rosado, A; Ramos, JA; Rojo, A; Romero, J | 1 |
| Bordet, R; Ridray, S; Schwartz, JC; Sokoloff, P | 1 |
| Hikida, T; Ichinose, H; Kaneko, S; Kreitman, RJ; Nagatsu, T; Nakanishi, S; Pastan, I; Watanabe, D | 1 |
| Andren, PE; Gunne, L; Svenningsson, P | 1 |
| Ganguly, A; Keefe, KA | 1 |
| Andersson, KE; Andersson, M; Cenci, MA; Johansson, PA | 1 |
| Andrén, PE; Gunne, L; Hurd, YL; Pirker, W; Pontén, H; Tedroff, J | 1 |
| Carta, A; Fenu, S; Morelli, M | 1 |
| Ding, YM; Fu, Y; Jin, GZ; Tang, FM; Yu, LP; Zhang, GY | 1 |
| Campbell, BM; Gresch, PJ; Walker, PD | 1 |
| Andersson, M; Cenci, MA; Lundblad, M; Westin, JE | 1 |
| Kitai, ST; Steiner, H | 1 |
| Andersson, M; Cenci, MA; Konradi, C | 1 |
| Groenewegen, HJ; Van De Witte, SV; Voorn, P | 1 |
| Besson, MJ; Durand, C; Mathieu-Kia, AM; Penit-Soria, J | 1 |
| Forni, C; Kerkerian-Le Goff, L; Manrique, C; Salin, P | 1 |
| Akil, H; Badiani, A; Day, HE; Oates, MM; Robinson, TE; Vittoz, NM; Watson, SJ | 1 |
| Björklund, A; Cenci, MA; Kirik, D; Winkler, C | 1 |
| Cenci, MA | 1 |
| Andrén, PE; Gunne, L; Klintenberg, R; Svenningsson, P | 1 |
| Aoyama, S; Kase, H; Kobayashi, H; Koga, K; Kuwana, Y; Miyaji, H; Mori, A; Sekine, S; Uchimura, T | 1 |
| Bonastre, M; Hirsch, EC; Marin, C; Périer, C; Tolosa, E | 1 |
| Cenci, MA; Lundblad, M; Vaudano, E | 1 |
| Bentlage, C; Björklund, A; Cenci, MA; Nikkhah, G; Winkler, C | 1 |
| Bonastre, M; Hirsch, EC; Jimenez, A; Marin, C; Périer, C; Tolosa, E | 1 |
| Bernardi, G; D'Angelo, V; Fusco, FR; Martorana, A; Sancesario, G | 1 |
| Lim, MM; Murphy, AZ; Young, LJ | 1 |
| Brotchie, JM; Chalon, S; Crossman, AR; Ravenscroft, P | 1 |
| Carta, AR; Morelli, M; Pinna, A; Tronci, E | 1 |
| Bové, J; Cortés, R; Marin, C; Mengod, G; Serrats, J; Tolosa, E | 1 |
| Martín, AB; Mendialdua, A; Moratalla, R; Pavón, N | 1 |
| Ariano, MA; Buchanan, TM; Collier, TJ; Elsworth, JD; Grissell, AE; Littlejohn, FC; Steece-Collier, K | 1 |
| Amalric, M; Breysse, N; Kerkerian-Le Goff, L; Oueslati, A; Salin, P | 1 |
| Cox, J; Sivam, SP | 1 |
| Aguilar, E; Bové, J; Cortés, R; Marin, C; Mengod, G; Serrats, J | 1 |
| Dagostino, P; Katz, J; Soghomonian, JJ; Wang, H | 1 |
| Borsini, F; Carminati, P; Frau, L; Morelli, M; Schintu, N; Simola, N; Tronci, E | 1 |
| Guan, Q; He, Y; Tan, L; Zhan, Q | 1 |
| Cheetham, S; Jenner, P; Lane, EL | 1 |
| Annalisa, P; Carta, AR; Frau, L; Lucia, F; Micaela, M; Morelli, M; Nicola, S; Nicoletta, S; Pinna, A; Pontis, S; Schintu, N; Silvia, P; Simola, N | 1 |
| Danysz, W; Dekundy, A; Quack, G; Valastro, B | 1 |
| Aubert, I; Berthet, A; Bezard, E; Bloch, B; Cenci, MA; Doudnikoff, E; Hengerer, B; Ittrich, C; Rylander, D; Schuster, S; Surmeier, DJ | 1 |
| Brotchie, JM; Fox, SH; Johnston, T; Millan, MJ; Reyes, G; Visanji, NP | 1 |
| Andrén, PE; Fälth, M; Kultima, K; Nilsson, A; Sköld, K; Svenningsson, P; Zhang, X | 1 |
| Aguilar, E; Cortés, R; Marin, C; Mengod, G; Obeso, JA | 1 |
| Dunnett, SB; Lane, EL | 1 |
| Cenci, MA; Crossman, AR; Kobylecki, C; Ravenscroft, P | 1 |
| Burdett, TC; Cassin, JJ; Chen, JF; Fredholm, BB; Healy, B; Schwarzschild, MA; Xiao, D | 1 |
| Capper-Loup, C; Frey, CM; Kaelin-Lang, A; Rebell, D | 1 |
| Courade, JP; Cuvelier, L; Dardou, D; De Ryck, M; Foerch, P; Monlezun, S; Schiffmann, SN | 1 |
| Frau, L; Morelli, M; Simola, N | 1 |
| Bezard, E; Crossman, AR; Ko, WK; Martin-Negrier, ML; Ravenscroft, P | 1 |
| Bonastre, M; Cortés, R; Marin, C; Mengod, G; Rodríguez-Oroz, MC | 1 |
| Capper-Loup, C; Kaelin-Lang, A; Paganetti, P; Sgroi, S | 1 |
| Carlsson, T; Chiu, WH; Depboylu, C; Höglinger, GU; Keber, U; Klietz, M; Schäfer, MK; Weihe, E | 1 |
| Hoshino, N; Ishikawa, T; Muraoka, S; Nishimura, T; Okano, M; Satoyoshi, H; Takahata, K; Tsunekawa, H | 1 |
| Avnor, Y; Bishop, C; Chambers, NE; Conti, MM; Gross, L; Lanza, K; Meadows, SM; Ostock, CY | 1 |
4 review(s) available for enkephalin, leucine and oxidopamine
| Article | Year |
|---|---|
Intramembrane interactions between neurotensin receptors and dopamine D2 receptors as a major mechanism for the neuroleptic-like action of neurotensin.
Topics: Animals; Antipsychotic Agents; Apomorphine; Basal Ganglia; Behavior, Animal; Brain; Cell Membrane; Dopamine; Dopamine Agents; Enkephalins; gamma-Aminobutyric Acid; GTP-Binding Proteins; Neurons; Neurotensin; Oxidopamine; Rats; Receptors, Dopamine D2; Receptors, Neurotensin; Receptors, Neurotransmitter | 1992 |
Striatonigral prodynorphin: a model system for understanding opioid peptide function.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Corpus Striatum; Dopamine; Enkephalins; Hydroxydopamines; Locomotion; Motor Neurons; Movement; Naloxone; Neural Pathways; Oxidopamine; Protein Precursors; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, kappa; Substantia Nigra | 1990 |
Regulation of release and function of neuropeptides in the heart.
Topics: Adrenergic Fibers; Animals; Chromatography, High Pressure Liquid; Enkephalins; Guinea Pigs; Heart; Hydroxydopamines; Immunohistochemistry; In Vitro Techniques; Myocardium; Neuropeptide Y; Neuropeptides; Oxidopamine; Phentolamine | 1987 |
[The co-localization of monoamines and enkephalins in the central nervous system].
Topics: 5,6-Dihydroxytryptamine; 5,7-Dihydroxytryptamine; Amines; Animals; Brain; Catecholamines; Cats; Corpus Striatum; Enkephalin, Methionine; Enkephalins; Histocytochemistry; Hydroxydopamines; Hypothalamus; Immunologic Techniques; Locus Coeruleus; Neurons; Norepinephrine; Oxidopamine; Protein Precursors; Raphe Nuclei; Rats; Serotonin; Tissue Distribution | 1984 |
147 other study(ies) available for enkephalin, leucine and oxidopamine
| Article | Year |
|---|---|
Differential regulation of striatal preproenkephalin mRNA by D1 and D2 dopamine receptors.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Blotting, Northern; Corpus Striatum; Desipramine; Dopamine; Enkephalins; Ergolines; Gene Expression Regulation; Kinetics; Male; Nucleic Acid Hybridization; Oligonucleotide Probes; Oxidopamine; Protein Precursors; Quinpirole; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Reference Values; RNA, Messenger; Salicylamides; Stereotaxic Techniques | 1992 |
Quantitative in situ hybridization evidence for differential regulation of proenkephalin and dopamine D2 receptor mRNA levels in the rat striatum: effects of unilateral intrastriatal injections of 6-hydroxydopamine.
Topics: Animals; Autoradiography; Base Sequence; Corpus Striatum; Enkephalins; Functional Laterality; Gene Expression Regulation; Infusions, Parenteral; Male; Molecular Sequence Data; Neurons; Nucleic Acid Hybridization; Oligodeoxyribonucleotides; Oligonucleotide Probes; Organ Specificity; Oxidopamine; Phosphorus Radioisotopes; Protein Precursors; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D2; Reference Values; RNA, Messenger | 1992 |
D2 dopaminergic regulation of striatal preproenkephalin mRNA levels is mediated at least in part through cholinergic interneurons.
Topics: Acetylcholine; Animals; Blotting, Northern; Corpus Striatum; Dose-Response Relationship, Drug; Enkephalins; Interneurons; Kinetics; Male; Models, Neurological; Nucleic Acid Hybridization; Oligonucleotide Probes; Oxidopamine; Phosphorus Radioisotopes; Protein Precursors; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D2; RNA, Messenger; Salicylamides; Scopolamine | 1992 |
Effects of a unilateral 6-hydroxydopamine lesion and prolonged L-3,4-dihydroxyphenylalanine treatment on peptidergic systems in rat basal ganglia.
Topics: Animals; Carbidopa; Cholecystokinin; Chromatography, High Pressure Liquid; Corpus Striatum; Enkephalin, Leucine; Enkephalin, Methionine; Levodopa; Male; Neuropeptides; Neurotensin; Oxidopamine; Prosencephalon; Rats; Rats, Wistar; Substance P; Substantia Nigra | 1992 |
Differential regulation of neuropeptide mRNA expression in intrastriatal striatal transplants by host dopaminergic afferents.
Topics: Afferent Pathways; Animals; Autoradiography; Brain Tissue Transplantation; Caudate Nucleus; Corpus Striatum; Dopamine; Enkephalins; Female; Fetal Tissue Transplantation; Gene Expression Regulation; Haloperidol; In Situ Hybridization; Nucleus Accumbens; Oligonucleotide Probes; Oxidopamine; Protein Precursors; Putamen; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sulfur Radioisotopes; Tachykinins | 1992 |
A rostrocaudal gradient in the synthesis of enkephalin in nucleus accumbens.
Topics: Animals; Caudate Nucleus; Corpus Callosum; Enkephalins; Histocytochemistry; Male; Nucleus Accumbens; Oxidopamine; Protein Precursors; Rats; Rats, Inbred Strains; RNA, Messenger | 1992 |
Role of catecholamines in mediating messenger RNA and hormonal responses to stress.
Topics: Adrenocorticotropic Hormone; Animals; Brain; Catecholamines; Corticosterone; Corticotropin-Releasing Hormone; Enkephalins; Hormones; Male; Norepinephrine; Oxidopamine; Paraventricular Hypothalamic Nucleus; Protein Precursors; Rats; Rats, Inbred Strains; RNA, Messenger; Stress, Psychological | 1991 |
Lesion of dopamine mesolimbic neurons blocks behavioral effects induced by the endogenous enkephalins but not by a mu-opioid receptor agonist.
Topics: Amino Acid Sequence; Analgesics; Animals; Behavior, Animal; Dipeptides; Dopamine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Limbic System; Male; Molecular Sequence Data; Motor Activity; Neurons; Nucleus Accumbens; Oligopeptides; Oxidopamine; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Tegmentum Mesencephali | 1991 |
Dopaminergic system mediates only delta-opiate inhibition of endogenous acetylcholine release evoked by glutamate from rat striatal slices.
Topics: Acetylcholine; Animals; Benzazepines; Corpus Striatum; Dopamine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine-2-Alanine; Enkephalins; Glutamates; Glutamic Acid; Male; Morphine; Oxidopamine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Secretory Rate | 1991 |
A light and electron microscopical study of enkephalin-immunoreactive structures in the rat neostriatum after removal of the nigrostriatal dopaminergic pathway.
Topics: Animals; Caudate Nucleus; Corpus Striatum; Dendrites; Dopamine; Enkephalins; Gene Expression Regulation; Immunohistochemistry; Male; Microscopy, Electron; Oxidopamine; Putamen; Rats; Rats, Inbred Strains; Substantia Nigra; Synapses; Tegmentum Mesencephali; Tyrosine 3-Monooxygenase | 1991 |
Neuroendocrine control of the gonads.
Topics: Animals; Brain; Endorphins; Enkephalins; Female; Gonads; Humans; Hypothalamus; Male; Naloxone; Neurosecretory Systems; Neurotransmitter Agents; Ovary; Oxidopamine; Rats; Testis; Testosterone; Vagus Nerve; Vasectomy | 1991 |
Levodopa replacement therapy alters enzyme activities in striatum and neuropeptide content in striatal output regions of 6-hydroxydopamine lesioned rats.
Topics: Animals; Choline O-Acetyltransferase; Corpus Striatum; Drug Administration Schedule; Dynorphins; Enkephalins; Functional Laterality; Globus Pallidus; Glutamate Decarboxylase; Levodopa; Male; Oxidopamine; Rats; Rats, Inbred Strains; Substance P; Substantia Nigra | 1991 |
Intrastriatal implants of fetal mesencephalic cells attenuate the increases in striatal proenkephalin mRNA observed after unilateral 6-hydroxydopamine-induced lesions of the striatum.
Topics: Animals; Base Sequence; Brain Tissue Transplantation; Corpus Striatum; Enkephalins; Fetal Tissue Transplantation; Functional Laterality; Male; Mesencephalon; Molecular Sequence Data; Oligonucleotide Probes; Oxidopamine; Protein Precursors; Rats; Rats, Inbred Strains; RNA, Messenger | 1991 |
Interaction between enkephalinergic and dopaminergic systems in stressful situations.
Topics: Animals; Apomorphine; Conditioning, Operant; Corpus Striatum; Dopamine; Enkephalin, Methionine; Enkephalins; Hydroxydopamines; Male; Mice; Mice, Inbred Strains; Motor Activity; Neurons; Oxidopamine; Pimozide; Receptors, Dopamine; Stress, Psychological | 1991 |
Neostriatal dopaminergic terminals prevent the GABAergic involvement in the mu- and delta-opioid inhibition of KCl-evoked endogenous acetylcholine release.
Topics: Acetylcholine; Animals; Corpus Striatum; Dopamine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; gamma-Aminobutyric Acid; Male; Nerve Endings; Oxidopamine; Potassium Chloride; Rats; Rats, Inbred Strains | 1991 |
Enkephalin-containing nerve cell bodies in the substantia nigra of the rat: demonstration by immunohistochemistry and in situ hybridization.
Topics: Animals; Colchicine; Enkephalin, Methionine; Enkephalins; Immunoenzyme Techniques; Immunohistochemistry; Mesencephalon; Neurons; Nucleic Acid Hybridization; Organ Specificity; Oxidopamine; Protein Precursors; Rats; Rats, Inbred Strains; RNA, Messenger; Substantia Nigra | 1991 |
Differential modulation of striatonigral dynorphin and enkephalin by dopamine receptor subtypes.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Apomorphine; Corpus Striatum; Dynorphins; Enkephalins; Ergolines; Hydroxydopamines; Male; Oxidopamine; Quinpirole; Rats; Rats, Inbred F344; Receptors, Dopamine; Substantia Nigra | 1990 |
Influence of nigrostriatal dopaminergic tone on the biosynthesis of dynorphin and enkephalin in rat striatum.
Topics: Animals; Apomorphine; Corpus Striatum; Dextroamphetamine; Dopamine; Dynorphins; Enkephalins; Hydroxydopamines; Male; Oxidopamine; Rats; Rats, Inbred F344; Reference Values; RNA, Messenger; Substantia Nigra | 1990 |
Autoradiographic localization of delta opioid receptors within the mesocorticolimbic dopamine system using radioiodinated [2-D-penicillamine, 5-D-penicillamine]enkephalin (125I-DPDPE).
Topics: Animals; Autoradiography; Binding, Competitive; Cerebral Cortex; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Hydroxydopamines; Immunochemistry; In Vitro Techniques; Iodine Radioisotopes; Limbic System; Male; Oxidopamine; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Sympathectomy, Chemical; Tyrosine 3-Monooxygenase | 1990 |
The effects of nigrostriatal 6-hydroxydopamine lesions on dopamine D2 receptor mRNA and opioid systems.
Topics: Animals; Corpus Striatum; Enkephalins; Hydroxydopamines; Oxidopamine; Rats; Receptors, Dopamine; RNA, Messenger; Substantia Nigra; Tissue Distribution | 1990 |
Adrenergic regulation of hypothalamic proenkephalin neurons: evidence for opposite effects in subpopulations terminating in median eminence and neurointermediate pituitary.
Topics: Animals; Enkephalin, Methionine; Enkephalins; Hydroxydopamines; Hypothalamus; In Vitro Techniques; Male; Median Eminence; Methoxamine; Neural Pathways; Neurons; Oxidopamine; Pituitary Gland, Posterior; Protein Precursors; Rats; Rats, Inbred Strains; Reserpine; Sympathetic Nervous System | 1990 |
Nerve growth factor (NGF) potentiates the changes in striatal proenkephalin mRNAs subsequent to 6-hydroxydopamine-induced lesions of the substantia nigra.
Topics: Animals; Base Sequence; Corpus Striatum; Enkephalins; Hydroxydopamines; Male; Molecular Sequence Data; Nerve Growth Factors; Nucleic Acid Hybridization; Oxidopamine; Protein Precursors; Rats; Rats, Inbred Strains; RNA, Messenger; Substantia Nigra | 1990 |
Behavioral effects of endogenous or exogenous (mu, delta) opioid peptides: relation with DA mesolimbic pathways.
Topics: Animals; Dipeptides; Dopamine; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Hydroxydopamines; Limbic System; Male; Motor Activity; Oxidopamine; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu | 1990 |
Increase of enkephalin and decrease of substance P immunoreactivity in the dorsal and ventral striatum of the rat after midbrain 6-hydroxydopamine lesions.
Topics: Afferent Pathways; Animals; Corpus Striatum; Dopamine; Efferent Pathways; Enkephalins; Histocytochemistry; Hydroxydopamines; Nucleus Accumbens; Oxidopamine; Rats; Substance P | 1987 |
Similar time course changes in striatal levels of glutamic acid decarboxylase and proenkephalin mRNA following dopaminergic deafferentation in the rat.
Topics: Animals; Corpus Striatum; Denervation; DNA Probes; Dopamine; Enkephalins; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Glutamate Decarboxylase; Hydroxydopamines; Kinetics; Male; Oxidopamine; Poly A; Protein Precursors; Rats; Rats, Inbred Strains; RNA; RNA, Messenger; Substantia Nigra; Tubulin | 1988 |
Distribution, projection and dopaminergic regulation of the neurokinin B mRNA-containing neurons of the rat caudate-putamen.
Topics: Animals; Caudate Nucleus; Cell Count; Dopamine; Enkephalins; Hydroxydopamines; Male; Neurokinin B; Nucleic Acid Hybridization; Oxidopamine; Putamen; Rats; Rats, Inbred Strains; RNA, Messenger; Substance P; Substantia Nigra | 1989 |
Autoradiographic localization of mu-opioid and neurotensin receptors within the mesolimbic dopamine system.
Topics: Animals; Autoradiography; Dopamine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Hydroxydopamines; Limbic System; Male; Oxidopamine; Rats; Rats, Inbred Strains; Receptors, Neurotensin; Receptors, Neurotransmitter; Receptors, Opioid; Receptors, Opioid, mu | 1989 |
Characterization of opioid receptors in rat nucleus accumbens following mesolimbic dopaminergic lesions.
Topics: Animals; Dopamine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Hydroxydopamines; Ibotenic Acid; Limbic System; Male; Nucleus Accumbens; Oxidopamine; Rats; Rats, Inbred Strains; Receptors, Opioid; Septal Nuclei | 1989 |
Localization of striatal opioid gene expression, and its modulation by the mesostriatal dopamine pathway: an in situ hybridization study.
Topics: Animals; Autoradiography; Brain; Corpus Striatum; Dopamine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Hydroxydopamines; Male; Nucleic Acid Hybridization; Oxidopamine; Protein Precursors; Rats; Rats, Inbred Strains; Receptors, Opioid; Reference Values; RNA, Messenger; Tritium | 1989 |
Rotational behavior mediated by dopaminergic and nondopaminergic mechanisms after intranigral microinjection of specific mu, delta and kappa opioid agonists.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Amphetamine; Animals; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Hydroxydopamines; Male; Microinjections; Motor Activity; Naloxone; Narcotics; Oxidopamine; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Rotation | 1988 |
Non-dopaminergic mechanisms in the turning behavior evoked by intranigral opiates.
Topics: Animals; Dynorphins; Enkephalins; Hydroxydopamines; Male; Medial Forebrain Bundle; Morphine; Movement; Naltrexone; Neural Pathways; Oxidopamine; Rats; Rats, Inbred Strains; Substantia Nigra | 1985 |
Mechanism of action of L-leucyl-glycinamide and its effect on Parkinson's disease.
Topics: Aged; Animals; Antiparkinson Agents; Brain; Enkephalin, Leucine; Female; Humans; Hydroxydopamines; Levodopa; Male; Middle Aged; MSH Release-Inhibiting Hormone; Oxidopamine; Parkinson Disease; Parkinson Disease, Secondary; Rats; Stereotyped Behavior | 1987 |
On the presence of opioid receptors in guinea-pig ventricular tissue.
Topics: Animals; Dynorphins; Electric Stimulation; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Guinea Pigs; Heart; Hydroxydopamines; In Vitro Techniques; Myocardium; Naloxone; Narcotics; Norepinephrine; Oxidopamine; Peptide Fragments; Protease Inhibitors; Receptors, Opioid; Sympathetic Nervous System | 1987 |
Identification of pre- and postsynaptic bradykinin receptor sites in the vas deferens: evidence for different structural prerequisites.
Topics: Animals; Cold Temperature; Denervation; Enkephalins; Hydroxydopamines; Male; Neurotensin; Norepinephrine; Oxidopamine; Rats; Rats, Inbred Strains; Receptors, Bradykinin; Receptors, Neurotransmitter; Structure-Activity Relationship; Tetrodotoxin; Vas Deferens; Vasopressins | 1987 |
Neonatal and adult 6-hydroxydopamine-induced lesions differentially alter tachykinin and enkephalin gene expression.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Aging; Animals; Animals, Newborn; Benzazepines; Corpus Striatum; Dopamine; Dynorphins; Enkephalin, Methionine; Enkephalins; Ergolines; Female; Gene Expression Regulation; Hippocampus; Hydroxydopamines; Male; Motor Activity; Neuropeptides; Oxidopamine; Peptide Fragments; Protein Precursors; Quinpirole; Rats; Rats, Inbred Strains; RNA, Messenger; Substantia Nigra; Tachykinins | 1987 |
Interaction between enkephalin and dopamine in the avian retina.
Topics: Animals; Chickens; Dopamine; Enkephalins; Hydroxydopamines; In Vitro Techniques; Kinetics; Morphine; Oxidopamine; Receptors, Opioid; Retina; Tyrosine 3-Monooxygenase | 1987 |
Dopaminergic regulation of proenkephalin-A gene expression in the basal ganglia.
Topics: Animals; Basal Ganglia; Corpus Striatum; Dopamine; Dynorphins; Enkephalins; Genes; Hydroxydopamines; Oxidopamine; Protein Precursors; Rats; Rats, Inbred Strains; Transcription, Genetic | 1986 |
Distorted development of intracerebral grafts: long-term maintenance of tyrosine hydroxylase-containing neurons in grafts of cortical tissue.
Topics: Aging; Animals; Brain; Dopamine; Enkephalins; Frontal Lobe; Graft Survival; Hydroxydopamines; Immunohistochemistry; Male; Neuronal Plasticity; Neuropeptide Y; Oxidopamine; Rats; Rats, Inbred Strains; Tyrosine 3-Monooxygenase | 1988 |
Gamma-aminobutyric acid and benzodiazepine receptor changes induced by unilateral 6-hydroxydopamine lesions of the medial forebrain bundle.
Topics: Animals; Autoradiography; Benzodiazepines; Brain; Dopamine; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Flunitrazepam; Hydroxydopamines; Kinetics; Muscimol; Naloxone; Oxidopamine; Rats; Rats, Inbred Strains; Receptors, GABA-A; Spiperone; Tritium | 1985 |
Reduction of striatal dopaminergic neurotransmission elevates striatal proenkephalin mRNA.
Topics: Animals; Autoradiography; Corpus Striatum; Dopamine; Enkephalins; Hydroxydopamines; In Vitro Techniques; Oxidopamine; Protein Precursors; Rats; RNA, Messenger; Synaptic Transmission | 1986 |
The effect of chronic imipramine and electroconvulsive shock treatment on [3H]DADLE binding to cortical membranes of rats pretreated with chronic reserpine or 6-hydroxydopamine.
Topics: Animals; Cell Membrane; Cerebral Cortex; Electroshock; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Hydroxydopamines; Imipramine; Male; Oxidopamine; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Reserpine | 1987 |
Possible mediation of catecholaminergic pathways in the antinociceptive effect of an extract of Cannabis sativa L.
Topics: Analgesics; Animals; Benzomorphans; Cannabis; Dose-Response Relationship, Drug; Enkephalin, Leucine; Haplorhini; Hydroxydopamines; Male; Mice; Naloxone; Naltrexone; Narcotic Antagonists; Oxidopamine; Plant Extracts; Rats; Rats, Inbred Strains | 1986 |
Regulation of striatal enkephalin turnover in rats receiving antagonists of specific dopamine receptor subtypes.
Topics: Animals; Benzazepines; Corpus Striatum; Enkephalins; Hydroxydopamines; Male; Neurons; Oxidopamine; Protein Precursors; Rats; Rats, Inbred Strains; Receptors, Dopamine; RNA, Messenger; Sulpiride | 1987 |
Role of endogenous enkephalins in locomotion evidenced by acetorphan, an "enkephalinase" inhibitor.
Topics: Amino Acids, Sulfur; Animals; Dose-Response Relationship, Drug; Enkephalins; Hydroxydopamines; Male; Metalloendopeptidases; Mice; Motor Activity; Naloxone; Neprilysin; Oxidopamine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Thiorphan; Tiopronin | 1987 |
Dopaminergic neurons of the substantia nigra modulate preproenkephalin A gene expression in rat striatal neurons.
Topics: Animals; Corpus Striatum; Enkephalins; Gene Expression Regulation; Genes; Histocytochemistry; Hydroxydopamines; Male; Neurons; Nucleic Acid Hybridization; Oxidopamine; Protein Precursors; Rats; Reference Values; RNA, Messenger; Substantia Nigra; Transcription, Genetic | 1988 |
Enkephalins in the heart.
Topics: Animals; Electric Stimulation; Endorphins; Enkephalins; Guinea Pigs; Heart; Hydroxydopamines; Myocardial Contraction; Myocardium; Oxidopamine; Protein Precursors; Radioimmunoassay; Sympathetic Nervous System | 1984 |
Subthalamic nucleus lesions: widespread effects on changes in gene expression induced by nigrostriatal dopamine depletion in rats.
Topics: Animals; Apomorphine; Behavior, Animal; Corpus Striatum; Dopamine; Enkephalins; Gene Expression Regulation; Globus Pallidus; Glutamate Decarboxylase; Male; Oxidopamine; Rats; Rats, Sprague-Dawley; RNA, Messenger; Somatostatin; Stereotyped Behavior; Substance P; Substantia Nigra; Thalamic Nuclei | 1995 |
Rostrocaudal subregional differences in the response of enkephalin, dynorphin and substance P synthesis in rat nucleus accumbens to dopamine depletion.
Topics: Animals; Dopamine; Dynorphins; Enkephalins; Male; Neural Pathways; Nucleus Accumbens; Oxidopamine; Protein Precursors; Rats; Rats, Wistar; Receptors, Dopamine; RNA, Messenger; Substance P; Tachykinins | 1994 |
Temporal dissociation between changes in striatal enkephalin and substance P messenger RNAs following striatal dopamine depletion.
Topics: Animals; Corpus Striatum; Dopamine; Enkephalins; Male; Oxidopamine; Rats; Rats, Sprague-Dawley; RNA, Messenger; Substance P; Time Factors | 1994 |
Neurotrophic factor gene expression in astrocytes during development and following injury.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Astrocytes; Blotting, Northern; Brain-Derived Neurotrophic Factor; Cells, Cultured; Enkephalin, Methionine; Enkephalins; Gene Expression Regulation, Developmental; Glial Fibrillary Acidic Protein; Male; Nerve Growth Factors; Nerve Tissue Proteins; Nucleic Acid Hybridization; Oxidopamine; Protein Precursors; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; RNA; Substantia Nigra; Sympathectomy, Chemical | 1994 |
Dopaminergic and muscarinic regulation of striatal enkephalin and substance P messenger RNAs following striatal dopamine denervation: effects of systemic and central administration of quinpirole and scopolamine.
Topics: Animals; Corpus Striatum; Denervation; Dopamine; Dopamine Agonists; Enkephalins; Ergolines; Infusion Pumps; Injections, Intraventricular; Male; Muscarine; Oxidopamine; Quinpirole; Rats; Rats, Sprague-Dawley; RNA, Messenger; Scopolamine; Substance P | 1994 |
Chronic L-DOPA treatment differentially regulates gene expression of glutamate decarboxylase, preproenkephalin and preprotachykinin in the striatum of 6-hydroxydopamine-lesioned rat.
Topics: Animals; Base Sequence; Behavior, Animal; Carbidopa; Enkephalins; Female; Gene Expression Regulation, Enzymologic; Glutamate Decarboxylase; In Situ Hybridization; Levodopa; Molecular Sequence Data; Neostriatum; Oligonucleotide Probes; Oxidopamine; Protein Precursors; Rats; Rats, Wistar; RNA, Messenger; Tachykinins | 1995 |
Chronic blockade of muscarinic cholinergic receptors by systemic trihexyphenidyl (Artane) administration modulates but does not mediate the dopaminergic regulation of striatal prepropeptide messenger RNA expression.
Topics: Animals; Autoradiography; Dopamine; Dynorphins; Enkephalins; In Situ Hybridization; Male; Muscarinic Antagonists; Neostriatum; Oxidopamine; Pirenzepine; Protein Precursors; Rats; Rats, Wistar; RNA, Messenger; Substantia Nigra; Sympathectomy, Chemical; Tachykinins; Trihexyphenidyl | 1995 |
Adenosine A2 receptors regulate the gene expression of striatopallidal and striatonigral neurons.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Caffeine; Corpus Striatum; Enkephalins; Gene Expression Regulation; Globus Pallidus; Neurons; Oxidopamine; Rats; Rats, Wistar; Receptors, Dopamine D2; Receptors, Purinergic; Substance P; Substantia Nigra | 1993 |
Ultrastructure of Met5-enkephalin terminals in the caudate-putamen nuclei of adult rats receiving neonatal intranigral 6-hydroxydopamine.
Topics: Animals; Autoradiography; Dopamine; Enkephalin, Methionine; Enkephalins; Immunohistochemistry; Lesch-Nyhan Syndrome; Male; Microscopy, Electron; Neostriatum; Oxidopamine; Protein Precursors; Rats; Receptors, Opioid; Synapses | 1994 |
Effects of neonatal 6-hydroxydopamine injections on glutamate decarboxylase, preproenkephalin and dopamine D2 receptor mRNAs in the adult rat striatum.
Topics: Animals; Animals, Newborn; Corpus Striatum; Enkephalins; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Injections, Intraventricular; Oxidopamine; Protein Precursors; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; RNA, Messenger; Tyrosine 3-Monooxygenase | 1993 |
The mechanism involved in the central effect of 5-leu enkephalin on the calcitonin secretion.
Topics: Animals; Calcitonin; Drug Interactions; Enkephalin, Leucine; Injections, Intraventricular; Naloxone; Narcotic Antagonists; Oxidopamine; Rats; Receptors, Opioid, delta; Receptors, Opioid, mu; Somatostatin; Sympathectomy, Chemical; Thyroid Gland | 1993 |
Prefrontal corticostriatal afferents maintain increased enkephalin gene expression in the dopamine-denervated rat striatum.
Topics: Animals; Autoradiography; Denervation; Dopamine; Enkephalins; Female; Gene Expression; Histocytochemistry; In Situ Hybridization; Neostriatum; Neural Pathways; Neurons, Afferent; Oxidopamine; Prefrontal Cortex; Protein Precursors; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sympathectomy, Chemical; Tachykinins | 1994 |
Differential regulation of glutamate decarboxylase and preproenkephalin mRNA levels in the rat striatum.
Topics: Aging; Animals; Animals, Newborn; Autoradiography; Dopamine; Enkephalins; Female; Glutamate Decarboxylase; Haloperidol; In Situ Hybridization; Neostriatum; Neurons; Oxidopamine; Pertussis Toxin; Pregnancy; Protein Precursors; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sulpiride; Virulence Factors, Bordetella | 1994 |
Brain-derived neurotrophic factor enhances striatal neuropeptide expression in both the intact and the dopamine-depleted rat striatum.
Topics: Animals; Brain-Derived Neurotrophic Factor; Corpus Striatum; Dopamine; Enkephalins; Female; Gene Expression Regulation; In Situ Hybridization; Injections; Nerve Tissue Proteins; Oxidopamine; Parkinson Disease, Secondary; Protein Precursors; Rats; Rats, Sprague-Dawley; Receptor, Ciliary Neurotrophic Factor; Receptors, Growth Factor; RNA, Messenger; Tachykinins | 1994 |
Disruption of target interactions prevents the development of enkephalin immunoreactivity in sympathetic neurons.
Topics: Animals; Animals, Newborn; Denervation; Enkephalins; Ganglia, Sympathetic; Immunohistochemistry; Nerve Regeneration; Neurons; Neuropeptide Y; Oxidopamine; Rats; Rats, Sprague-Dawley; Reference Values; Submandibular Gland | 1994 |
Quantitation of the levels of tyrosine hydroxylase and preproenkephalin mRNAs in nigrostriatal sites after 6-hydroxydopamine lesions.
Topics: Animals; Apomorphine; Brain Diseases; Corpus Striatum; Dopamine; Enkephalins; Gene Expression; Male; Neurons; Oxidopamine; Protein Precursors; Rats; Rats, Sprague-Dawley; RNA, Messenger; Substantia Nigra; Tyrosine 3-Monooxygenase | 1993 |
Trophic factor production by reactive astrocytes in injured brain.
Topics: Aging; Animals; Astrocytes; Biomarkers; Cells, Cultured; Cerebellum; Enkephalin, Methionine; Enkephalins; Fetus; Glial Fibrillary Acidic Protein; Male; Mice; Mice, Inbred C57BL; MPTP Poisoning; Nerve Growth Factors; Neuropeptides; Neurotoxins; Oxidopamine; Protein Precursors; Rats; Rats, Sprague-Dawley; RNA, Messenger; Somatostatin | 1993 |
Neuropeptide messenger RNA expression in the 6-hydroxydopamine-lesioned rat striatum reinnervated by fetal dopaminergic transplants: differential effects of the grafts on preproenkephalin, preprotachykinin and prodynorphin messenger RNA levels.
Topics: Animals; Apomorphine; Autoradiography; Behavior, Animal; Brain Tissue Transplantation; Dopamine; Enkephalins; Female; Fetal Tissue Transplantation; In Situ Hybridization; Neostriatum; Neuropeptides; Oxidopamine; Piperazines; Protein Precursors; Rats; Rats, Sprague-Dawley; RNA, Messenger; Stereotyped Behavior; Sympathectomy, Chemical; Tachykinins | 1993 |
Time-course of changes in striatal levels of DA uptake sites, DA D2 receptor and preproenkephalin mRNAs after nigrostriatal dopaminergic denervation in the rat.
Topics: Animals; Apomorphine; Biological Transport; Corpus Striatum; Dopamine; Enkephalins; In Situ Hybridization; Male; Motor Activity; Neurons; Oxidopamine; Piperazines; Protein Precursors; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; RNA, Messenger; Substantia Nigra; Time Factors | 1993 |
Long-term changes in striatal opioid systems after 6-hydroxydopamine lesion of rat substantia nigra.
Topics: Animals; Corpus Striatum; Dopamine; Down-Regulation; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine-2-Alanine; Enkephalins; Gene Expression Regulation; Male; Mazindol; Oxidopamine; Protein Precursors; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Receptors, Opioid; RNA, Messenger; Substantia Nigra; Time Factors | 1993 |
Transplantation of fetal nigral cells reverses the increase of preproenkephalin mRNA levels in the rat striatum caused by 6-OHDA lesion of the dopaminergic nigrostriatal pathway: a quantitative in situ hybridization study.
Topics: Animals; Autoradiography; Binding Sites; Brain Tissue Transplantation; Corpus Striatum; Enkephalins; Fetal Tissue Transplantation; In Situ Hybridization; Male; Oxidopamine; Phosphorus Radioisotopes; Piperazines; Protein Precursors; Rats; Rats, Wistar; Reference Values; RNA, Messenger; Substantia Nigra; Time Factors; Tritium | 1993 |
Effects of unilateral 6-hydroxydopamine lesions on neuropeptide immunoreactivity in the basal ganglia of the common marmoset, Callithrix jacchus, a quantitative immunohistochemical analysis.
Topics: Animals; Basal Ganglia; Behavior, Animal; Callithrix; Dopamine; Dopamine Agents; Enkephalin, Methionine; Enkephalins; Immunohistochemistry; MPTP Poisoning; Neostriatum; Neuropeptides; Oxidopamine; Substance P; Sympatholytics; Tyrosine 3-Monooxygenase | 1995 |
Dopamine receptor agonists regulate levels of the serotonin 5-HT2A receptor and its mRNA in a subpopulation of rat striatal neurons.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Adrenergic Agents; Amphetamines; Animals; Animals, Newborn; Apomorphine; Autoradiography; Binding, Competitive; Dopamine Agonists; Enkephalins; Female; In Situ Hybridization; Iodine Radioisotopes; Microinjections; Motor Activity; Neostriatum; Neurons; Oxidopamine; Pregnancy; Protein Precursors; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Serotonin; RNA, Messenger; Serotonin Receptor Agonists | 1996 |
Partial striatal dopamine depletion differentially affects striatal substance P and enkephalin messenger RNA expression.
Topics: Animals; Corpus Striatum; Dopamine; Enkephalins; In Situ Hybridization; Male; Oxidopamine; Rats; Rats, Sprague-Dawley; RNA, Messenger; Substance P; Tyrosine 3-Monooxygenase | 1996 |
Effect of repeated administration of dopamine agonists on striatal neuropeptide mRNA expression in rats with a unilateral nigral 6-hydroxydopamine lesion.
Topics: Animals; Dopamine Agonists; Enkephalins; In Situ Hybridization; Male; Neostriatum; Neuropeptides; Oligonucleotide Probes; Oxidopamine; Protein Precursors; Rats; Rats, Wistar; Receptors, Dopamine D1; Receptors, Dopamine D2; RNA, Messenger; Substantia Nigra; Sympathectomy, Chemical; Sympatholytics; Tachykinins | 1996 |
Intrastriatal injection of opioid receptor agonists inhibits apomorphine-induced behavior in 6-hydroxydopamine-treated mice.
Topics: Animals; Apomorphine; Behavior, Animal; Corpus Striatum; Dopamine; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Male; Mice; Naltrexone; Oxidopamine; Peptide Fragments; Receptors, Opioid | 1995 |
Partial reversal of increased preproenkephalin messenger ribonucleic acid (mRNA) and decreased preprotachykinin mRNA by foetal dopamine cells in unilateral 6-hydroxydopamine-lesioned rat striatum parallels functional recovery.
Topics: Animals; Brain Tissue Transplantation; Corpus Striatum; Dominance, Cerebral; Dopamine; Enkephalins; Female; Fetal Tissue Transplantation; Gene Expression; Male; Mesencephalon; Nerve Regeneration; Oxidopamine; Protein Precursors; Rats; Rats, Wistar; RNA, Messenger; Stereotyped Behavior; Substantia Nigra; Tachykinins | 1996 |
Bilateral 6-hydroxydopamine-induced lesion of the nigrostriatal dopamine pathway reproduces the effects of unilateral lesion on substance P but not on enkephalin expression in rat basal ganglia.
Topics: Animals; Basal Ganglia; Corpus Striatum; Dopamine; Enkephalins; Female; Functional Laterality; Immunohistochemistry; Neural Pathways; Neurons; Neurotoxins; Oxidopamine; Rats; Rats, Wistar; RNA, Messenger; Substance P; Substantia Nigra | 1996 |
Enhancement of the behavioral response to apomorphine administration following repeated treatment in the 6-hydroxydopamine-lesioned rat is temporally correlated with a rise in striatal preproenkephalin-B, but not preproenkephalin-A, gene expression.
Topics: Adrenergic Agents; Animals; Apomorphine; Caudate Nucleus; Corpus Striatum; Enkephalins; Gene Expression Regulation; Hyperkinesis; Locomotion; Male; Nucleus Accumbens; Oxidopamine; Protein Precursors; Putamen; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; RNA, Messenger; Rotation; Time Factors | 1997 |
Differential regional effects of long-term L-DOPA treatment on preproenkephalin and preprotachykinin gene expression in the striatum of 6-hydroxydopamine-lesioned rat.
Topics: Animals; Corpus Striatum; Enkephalins; Female; Gene Expression; Immunohistochemistry; In Situ Hybridization; Levodopa; Oxidopamine; Protein Precursors; Rats; Rats, Wistar; Tachykinins; Time Factors | 1997 |
Plasticity of striatopallidal terminals following unilateral lesion of the dopaminergic nigrostriatal pathway: a morphological study.
Topics: Animals; Dopamine; Enkephalins; Globus Pallidus; Immunohistochemistry; Male; Neostriatum; Neural Pathways; Neuronal Plasticity; Oxidopamine; Presynaptic Terminals; Rats; Rats, Wistar; Substantia Nigra | 1997 |
Fine-tuning control of testicular functions.
Topics: Animals; beta-Endorphin; Corticotropin-Releasing Hormone; Enkephalins; Immune Sera; Injections; Male; Naloxone; Narcotic Antagonists; Oxidopamine; Oxytocin; Rats; Rats, Sprague-Dawley; Rats, Wistar; Somatostatin; Sympathectomy; Testis; Vasectomy | 1997 |
Topographical organization of opioid peptide precursor gene expression following repeated apomorphine treatment in the 6-hydroxydopamine-lesioned rat.
Topics: Animals; Apomorphine; Brain; Caudate Nucleus; Disease Models, Animal; Enkephalins; Gene Expression Regulation; In Situ Hybridization; Male; Motor Activity; Nucleus Accumbens; Organ Specificity; Oxidopamine; Parkinson Disease; Protein Precursors; Putamen; Rats; Rats, Sprague-Dawley; Reference Values; Time Factors | 1998 |
Dopamine depletion reorganizes projections from the nucleus accumbens and ventral pallidum that mediate opioid-induced motor activity.
Topics: Analgesics, Opioid; Animals; Baclofen; Dopamine; Dopamine Antagonists; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Fluphenazine; GABA Agonists; Globus Pallidus; Locomotion; Male; Microinjections; Motor Activity; Motor Neurons; Muscimol; Neural Pathways; Nucleus Accumbens; Oxidopamine; Rats; Rats, Sprague-Dawley; Sympatholytics | 1998 |
L-DOPA-induced dyskinesia in the rat is associated with striatal overexpression of prodynorphin- and glutamic acid decarboxylase mRNA.
Topics: Animals; Autoradiography; Behavior, Animal; Corpus Striatum; Dyskinesia, Drug-Induced; Enkephalins; Female; Gene Expression Regulation; Glutamate Decarboxylase; In Situ Hybridization; Levodopa; Oxidopamine; Protein Precursors; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; RNA, Messenger; Tachykinins | 1998 |
Effect of repeated L-DOPA, bromocriptine, or lisuride administration on preproenkephalin-A and preproenkephalin-B mRNA levels in the striatum of the 6-hydroxydopamine-lesioned rat.
Topics: Animals; Autoradiography; Behavior, Animal; Bromocriptine; Dopamine Agents; Dopamine Agonists; Dopamine Uptake Inhibitors; Enkephalins; In Situ Hybridization; Levodopa; Lisuride; Male; Mazindol; Medial Forebrain Bundle; Neostriatum; Oligonucleotide Probes; Oxidopamine; Parkinson Disease, Secondary; Protein Precursors; Radioligand Assay; Rats; Rats, Sprague-Dawley; RNA, Messenger | 1999 |
Dopaminergic modulation of pallidal preproenkephalin mRNA.
Topics: Animals; Benzazepines; Dopamine; Dopamine Antagonists; Enkephalins; Gene Expression; Globus Pallidus; Male; Neurons; Oxidopamine; Protein Precursors; Rats; Rats, Sprague-Dawley; RNA, Messenger; Salicylamides; Substantia Nigra; Sulfur Radioisotopes; Sympatholytics | 1999 |
Gene expression of the GAD67 and GAD65 isoforms of glutamate decarboxylase is differentially altered in subpopulations of striatal neurons in adult rats lesioned with 6-OHDA as neonates.
Topics: Animals; Animals, Newborn; Brain Diseases; Corpus Striatum; Dynorphins; Enkephalins; Gene Expression; Glutamate Decarboxylase; Isoenzymes; Neurons; Oxidopamine; Protein Precursors; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tissue Distribution | 1999 |
Locomotor-activity-induced changes in striatal levels of preprotachykinin and preproenkephalin mRNA. Regulation by the dopaminergic and glutamatergic systems.
Topics: Animals; Apomorphine; Benzazepines; Corpus Striatum; Denervation; Dizocilpine Maleate; Dopamine; Dopamine Antagonists; Enkephalins; Excitatory Amino Acid Antagonists; Female; Gene Expression Regulation; Glutamic Acid; In Situ Hybridization; Motor Activity; Nerve Tissue Proteins; Oxidopamine; Protein Precursors; Rats; Rats, Sprague-Dawley; RNA, Messenger; Running; Tachykinins | 1999 |
Recovery after nigral grafting in 6-hydroxydopamine lesioned rats is due to graft function and not significantly influenced by the remaining ipsilateral or contralateral host dopaminergic system.
Topics: Animals; Behavior, Animal; Brain Tissue Transplantation; Dopamine; Enkephalins; Female; Functional Laterality; Immunohistochemistry; In Situ Hybridization; Oxidopamine; Protein Precursors; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; RNA, Messenger; Rotation; Substantia Nigra; Sympatholytics; Tachykinins; Tyrosine 3-Monooxygenase | 1999 |
Suppression of serotonin hyperinnervation does not alter the dysregulatory influences of dopamine depletion on striatal neuropeptide gene expression in rodent neonates.
Topics: 5,7-Dihydroxytryptamine; Animals; Animals, Newborn; Chromatography, High Pressure Liquid; Corpus Striatum; Denervation; Dopamine; Dynorphins; Enkephalins; Gene Expression Regulation; In Situ Hybridization; Neuropeptides; Nucleic Acid Hybridization; Oxidopamine; Protein Precursors; Rats; Rats, Sprague-Dawley; RNA, Messenger; Serotonin; Tachykinins | 1999 |
Fenfluramine-induced increase in preproenkephalin mRNA levels in the striatum: interaction between the serotonergic, glutamatergic, and dopaminergic systems.
Topics: 5,7-Dihydroxytryptamine; Adrenergic Agents; Animals; Benzazepines; Corpus Striatum; Dizocilpine Maleate; Enkephalins; Female; Fenfluramine; Oxidopamine; Protein Precursors; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Serotonin Agents | 2000 |
Unilateral 6-hydroxydopamine lesions of nigrostriatal dopaminergic neurons increased CB1 receptor mRNA levels in the caudate-putamen.
Topics: Animals; Corpus Striatum; Enkephalins; Male; Neostriatum; Oxidopamine; Protein Precursors; Rats; Rats, Wistar; Receptors, Cannabinoid; Receptors, Drug; RNA, Messenger; Substantia Nigra | 2000 |
Involvement of the direct striatonigral pathway in levodopa-induced sensitization in 6-hydroxydopamine-lesioned rats.
Topics: Animals; Antiparkinson Agents; Benzazepines; Binding, Competitive; Corpus Striatum; Denervation; Dizocilpine Maleate; Dopamine Agonists; Dopamine Antagonists; Enkephalins; Excitatory Amino Acid Antagonists; Gene Expression; Levodopa; Male; Neural Pathways; Neurons; Opioid Peptides; Oxidopamine; Parkinson Disease, Secondary; Protein Precursors; Rats; Rats, Wistar; Receptors, Dopamine D2; Receptors, Dopamine D3; RNA, Messenger; Substantia Nigra; Sympatholytics; Tachykinins; Tetrahydronaphthalenes; Tritium; Ventral Tegmental Area | 2000 |
Synaptic integration mediated by striatal cholinergic interneurons in basal ganglia function.
Topics: Acetylcholine; Animals; Apomorphine; Basal Ganglia; Choline O-Acetyltransferase; Corpus Striatum; Dopamine; Dopamine Agonists; Down-Regulation; Enkephalins; Immunotoxins; Interneurons; Mice; Mice, Transgenic; Motor Activity; Oxidopamine; Posture; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Glutamate; Substance P; Synapses | 2000 |
Stimulated serotonin release from hyperinnervated terminals subsequent to neonatal dopamine depletion regulates striatal tachykinin, but not enkephalin gene expression.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Animals, Newborn; Cerebral Ventricles; Corpus Striatum; Desipramine; Dopamine; Enkephalins; Gene Expression Regulation; Hydroxyindoleacetic Acid; Injections, Intraventricular; Oxidopamine; p-Chloroamphetamine; Protein Precursors; Rats; Rats, Sprague-Dawley; RNA, Messenger; Serotonin; Tachykinins; Transcription, Genetic | 2000 |
L-DOPA produces strong induction of c-fos messenger RNA in dopamine-denervated cortical and striatal areas of the common marmoset.
Topics: Animals; Benzazepines; Blotting, Western; Callithrix; Cerebral Cortex; Corpus Striatum; Denervation; Disease Models, Animal; Dopamine; Dopamine Agents; Dopamine Antagonists; Enkephalins; Gene Expression; Genes, Immediate-Early; Levodopa; Nerve Degeneration; Oxidopamine; Parkinson Disease; Protein Precursors; Proto-Oncogene Proteins c-fos; Raclopride; Radioligand Assay; Receptors, Dopamine D1; Receptors, Dopamine D2; RNA, Messenger; Substance P; Substantia Nigra; Sympatholytics; Tritium | 2000 |
Unilateral dopamine depletion increases expression of the 2A subunit of the N-methyl-D-aspartate receptor in enkephalin-positive and enkephalin-negative neurons.
Topics: Animals; Autoradiography; Corpus Striatum; Dopamine; Enkephalins; Gene Expression; In Situ Hybridization; Male; Neurons; Oxidopamine; Parkinsonian Disorders; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Sympatholytics | 2001 |
Alterations in cortical and basal ganglia levels of opioid receptor binding in a rat model of l-DOPA-induced dyskinesia.
Topics: Animals; Basal Ganglia; Behavior, Animal; Binding Sites; Cerebral Cortex; Diprenorphine; Disease Models, Animal; Dopamine Agents; Dyskinesia, Drug-Induced; Enkephalins; Female; Levodopa; Narcotic Antagonists; Oxidopamine; Protein Precursors; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; RNA, Messenger; Sympatholytics; Tritium | 2001 |
Coadministration of (-)-OSU6162 with l-DOPA normalizes preproenkephalin mRNA expression in the sensorimotor striatum of primates with unilateral 6-OHDA lesions.
Topics: Animals; Autoradiography; Callithrix; Caudate Nucleus; Corpus Striatum; Disease Models, Animal; Dopamine Agents; Drug Administration Schedule; Drug Therapy, Combination; Enkephalins; Female; In Situ Hybridization; Injections, Subcutaneous; Levodopa; Ligands; Male; Oxidopamine; Parkinson Disease, Secondary; Piperidines; Protein Precursors; Putamen; RNA, Messenger; Tritium | 2001 |
Serotonin 2A receptor regulation of striatal neuropeptide gene expression is selective for tachykinin, but not enkephalin neurons following dopamine depletion.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamines; Animals; Chromatography, High Pressure Liquid; Corpus Striatum; Dopamine; Enkephalins; Gene Expression Regulation; Hydroxyindoleacetic Acid; In Situ Hybridization; Ketanserin; Male; Neurons; Oxidopamine; Protein Precursors; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Ritanserin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Sympatholytics; Tachykinins; Transcription, Genetic | 2001 |
Alterations in GAD67, dynorphin and enkephalin mRNA in striatal output neurons following priming in the 6-OHDA model of Parkinson's disease.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Dopamine Agonists; Down-Regulation; Drug Interactions; Drug Tolerance; Dynorphins; Enkephalins; Gene Expression; Glutamate Decarboxylase; Isoenzymes; Levodopa; Neostriatum; Neurons; Oxidopamine; Parkinsonian Disorders; Quinpirole; Rats; RNA, Messenger; Sympatholytics; Up-Regulation | 2001 |
Relevance between striatal expression of Fos, proenkephalin mRNA, prodynorphin mRNA and rotation induced by l-stepholidine in 6-hydroxydopamine-lesioned rats.
Topics: Animals; Berberine; Dopamine Antagonists; Enkephalins; Gene Expression; Genes, fos; Oxidopamine; Protein Precursors; Rats; Rats, Sprague-Dawley; RNA, Messenger; Rotation | 2000 |
Neonatal dopamine depletion reveals a synergistic mechanism of mRNA regulation that is mediated by dopamine(D1) and serotonin(2) receptors and is targeted to tachykinin neurons of the dorsomedial striatum.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Animals, Newborn; Dopamine; Dopamine Agonists; Dopamine Antagonists; Drug Synergism; Enkephalins; Gene Expression Regulation, Developmental; Male; Movement Disorders; Neostriatum; Neurons; Oxidopamine; Protein Precursors; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Serotonin; RNA, Messenger; Serotonin Antagonists; Serotonin Receptor Agonists; Tachykinins | 2001 |
Persistent changes in striatal gene expression induced by long-term L-DOPA treatment in a rat model of Parkinson's disease.
Topics: Animals; Bromocriptine; Denervation; Disease Models, Animal; Dopamine Agents; Dopamine Agonists; Drug Administration Schedule; Enkephalins; Female; Gene Expression Regulation; Immunohistochemistry; Levodopa; Neostriatum; Oxidopamine; Parkinsonian Disorders; Protein Precursors; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sympatholytics | 2001 |
Unilateral striatal dopamine depletion: time-dependent effects on cortical function and behavioural correlates.
Topics: Animals; Behavior, Animal; DNA-Binding Proteins; Dopamine; Early Growth Response Protein 1; Enkephalins; Functional Laterality; Gene Expression Regulation; Immediate-Early Proteins; Male; Neostriatum; Neural Pathways; Neuronal Plasticity; Neurons; Nucleus Accumbens; Oxidopamine; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; RNA, Messenger; Somatosensory Cortex; Sympatholytics; Time Factors; Transcription Factors; Tyrosine 3-Monooxygenase; Vibrissae | 2001 |
cAMP response element-binding protein is required for dopamine-dependent gene expression in the intact but not the dopamine-denervated striatum.
Topics: Animals; Antiparkinson Agents; Cocaine; Corpus Striatum; Cyclic AMP Response Element-Binding Protein; Denervation; DNA; Dopamine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Administration Routes; Enkephalins; Female; Gene Expression; Levodopa; Oligonucleotides, Antisense; Oxidopamine; Parkinson Disease, Secondary; Protein Precursors; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; RNA, Messenger; Transcription Factor AP-1 | 2001 |
MK-801 alters the effects of priming with L-DOPA on dopamine D1 receptor-induced changes in neuropeptide mRNA levels in the rat striatal output neurons.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Disease Models, Animal; Dizocilpine Maleate; Dopamine Agents; Dopamine Agonists; Drug Interactions; Dynorphins; Dyskinesia, Drug-Induced; Enkephalins; Excitatory Amino Acid Antagonists; Immunohistochemistry; Levodopa; Male; Motor Activity; Neostriatum; Neurons; Neuropeptides; Oxidopamine; Parkinsonian Disorders; Protein Precursors; Rats; Rats, Wistar; Receptors, Dopamine D1; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Tachykinins; Tyrosine 3-Monooxygenase | 2002 |
Regulation of striatal neuropeptide mRNAs: effects of the 5-HT(2) antagonist SR46349B in adult rats with a neonatal 6-hydroxydopamine lesion.
Topics: Animals; Animals, Newborn; Denervation; Dopamine; Down-Regulation; Enkephalins; Fluorobenzenes; Neostriatum; Neurons; Neuropeptides; Oxidopamine; Phenols; Protein Precursors; Rats; Receptors, Serotonin; RNA, Messenger; Serotonin; Serotonin Antagonists; Sympatholytics; Tachykinins; Up-Regulation | 2002 |
High-frequency stimulation of the subthalamic nucleus selectively reverses dopamine denervation-induced cellular defects in the output structures of the basal ganglia in the rat.
Topics: Animals; Basal Ganglia; Behavior, Animal; Corpus Striatum; Dopamine; Electric Stimulation; Electron Transport Complex IV; Enkephalins; Entopeduncular Nucleus; Globus Pallidus; Glutamate Decarboxylase; Isoenzymes; Male; Oxidopamine; Parkinson Disease; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; RNA, Messenger; Substance P; Substantia Nigra; Subthalamic Nucleus | 2002 |
A 6-hydroxydopamine lesion of the mesostriatal dopamine system decreases the expression of corticotropin releasing hormone and neurotensin mRNAs in the amygdala and bed nucleus of the stria terminalis.
Topics: Amygdala; Animals; Cell Count; Corticotropin-Releasing Hormone; Dopamine; Enkephalins; In Situ Hybridization; Male; Neostriatum; Neurotensin; Oxidopamine; Rats; Rats, Sprague-Dawley; RNA, Messenger; Septal Nuclei; Sympathectomy, Chemical; Sympatholytics | 2002 |
L-DOPA-induced dyskinesia in the intrastriatal 6-hydroxydopamine model of parkinson's disease: relation to motor and cellular parameters of nigrostriatal function.
Topics: Afferent Pathways; Animals; Bacterial Proteins; Behavior, Animal; Biomarkers; Brain Mapping; Caudate Nucleus; Corpus Striatum; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Dyskinesia, Drug-Induced; Enkephalins; Female; Image Processing, Computer-Assisted; Levodopa; Motor Activity; Nerve Tissue Proteins; Oxidopamine; Parkinsonian Disorders; Protein Precursors; Proto-Oncogene Proteins c-fos; Putamen; Rats; Rats, Sprague-Dawley; RNA, Messenger; Severity of Illness Index; Substantia Nigra; Sympathectomy, Chemical; Transcription Factors | 2002 |
Transcription factors involved in the pathogenesis of L-DOPA-induced dyskinesia in a rat model of Parkinson's disease.
Topics: Animals; Antiparkinson Agents; Corpus Striatum; Disease Models, Animal; Dyskinesia, Drug-Induced; Enkephalins; Gene Expression Regulation; Levodopa; Oxidopamine; Parkinsonian Disorders; Protein Precursors; Proto-Oncogene Proteins c-fos; Rats; Sympatholytics; Transcription Factors | 2002 |
Naloxone reduces levodopa-induced dyskinesias and apomorphine-induced rotations in primate models of parkinsonism.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Benserazide; Callithrix; Dopamine; Dopamine Agents; Dopamine Antagonists; Dyskinesia, Drug-Induced; Enkephalins; Female; In Situ Hybridization; Levodopa; Male; Motor Activity; Naloxone; Narcotic Antagonists; Oxidopamine; Parkinson Disease, Secondary; Protein Precursors; RNA; Rotation; Stereotyped Behavior; Sympathectomy, Chemical | 2002 |
Distribution of adenosine A(2A) receptor antagonist KW-6002 and its effect on gene expression in the rat brain.
Topics: Administration, Oral; Adrenergic Antagonists; Animals; Carbon Radioisotopes; Corpus Striatum; Enkephalins; Gene Expression; Male; Neurons; Oxidopamine; Parkinsonian Disorders; Protein Precursors; Purinergic P1 Receptor Antagonists; Purines; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; RNA, Messenger; Sympatholytics; Tachykinins; Tissue Distribution | 2002 |
AMPA receptor antagonist LY293558 reverses preproenkephalin mRNA overexpression in the striatum of 6-OHDA-lesioned-rats treated with L-dopa.
Topics: Animals; Disease Models, Animal; Dizocilpine Maleate; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dyskinesia, Drug-Induced; Enkephalins; Excitatory Amino Acid Antagonists; Gene Expression Regulation; Isoquinolines; Levodopa; Male; Membrane Glycoproteins; Membrane Transport Proteins; Neostriatum; Nerve Tissue Proteins; Oxidopamine; Parkinsonian Disorders; Protein Precursors; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Tetrazoles | 2002 |
Cellular and behavioural effects of the adenosine A2a receptor antagonist KW-6002 in a rat model of l-DOPA-induced dyskinesia.
Topics: Animals; Behavior, Animal; Corpus Striatum; Disease Models, Animal; Drug Therapy, Combination; Dyskinesia, Drug-Induced; Enkephalins; Female; Levodopa; Motor Activity; Oxidopamine; Parkinsonian Disorders; Protein Precursors; Proto-Oncogene Proteins c-fos; Purinergic P1 Receptor Antagonists; Purines; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; RNA, Messenger; Treatment Outcome | 2003 |
Regulation of neuropeptide mRNA expression in the basal ganglia by intrastriatal and intranigral transplants in the rat Parkinson model.
Topics: Adrenergic Agents; Animals; Autoradiography; Basal Ganglia; Brain Mapping; Disease Models, Animal; Embryo, Mammalian; Enkephalins; Entopeduncular Nucleus; Female; Fetal Tissue Transplantation; Gene Expression Regulation; Glutamate Decarboxylase; Immunohistochemistry; In Situ Hybridization; Neuropeptides; Oxidopamine; Parkinsonian Disorders; Protein Precursors; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Regression Analysis; RNA, Messenger; Septal Nuclei; Substantia Nigra; Tachykinins | 2003 |
Effect of subthalamic nucleus or entopeduncular nucleus lesion on levodopa-induced neurochemical changes within the basal ganglia and on levodopa-induced motor alterations in 6-hydroxydopamine-lesioned rats.
Topics: Animals; Basal Ganglia; Corpus Striatum; Disease Models, Animal; Electron Transport Complex IV; Enkephalins; Entopeduncular Nucleus; Globus Pallidus; Glutamate Decarboxylase; In Situ Hybridization; Isoenzymes; Levodopa; Male; Motor Activity; Neurons; Oxidopamine; Parkinsonian Disorders; Protein Precursors; Rats; Rats, Sprague-Dawley; RNA, Messenger; Substantia Nigra; Subthalamic Nucleus | 2003 |
Enkephalin, neurotensin, and substance P immunoreactivite neurones of the rat GP following 6-hydroxydopamine lesion of the substantia nigra.
Topics: Animals; Enkephalins; Fluorescent Antibody Technique; Globus Pallidus; Immunohistochemistry; Male; Neurons; Neurotensin; Oxidopamine; Parvalbumins; Rats; Rats, Sprague-Dawley; Substance P; Substantia Nigra; Tyrosine 3-Monooxygenase | 2003 |
Ventral striatopallidal oxytocin and vasopressin V1a receptors in the monogamous prairie vole (Microtus ochrogaster).
Topics: Animals; Arvicolinae; Basal Ganglia; Binding Sites; Dopamine; Enkephalins; Female; Globus Pallidus; Immunohistochemistry; Male; Mice; Neural Pathways; Nucleus Accumbens; Oxidopamine; Oxytocin; Presynaptic Terminals; Protein Precursors; Receptors, Oxytocin; Receptors, Vasopressin; RNA, Messenger; Sex Characteristics; Sexual Behavior, Animal; Substance P; Vasopressins | 2004 |
Ropinirole versus L-DOPA effects on striatal opioid peptide precursors in a rodent model of Parkinson's disease: implications for dyskinesia.
Topics: Animals; Antiparkinson Agents; Behavior, Animal; Corpus Striatum; Disease Models, Animal; Dopamine Agonists; Dyskinesia, Drug-Induced; Enkephalins; Gene Expression; In Situ Hybridization; Indoles; Levodopa; Male; Motor Activity; Opioid Peptides; Oxidopamine; Parkinsonian Disorders; Protein Precursors; Rats; Rats, Sprague-Dawley; RNA, Messenger; Synaptic Transmission | 2004 |
Different responsiveness of striatonigral and striatopallidal neurons to L-DOPA after a subchronic intermittent L-DOPA treatment.
Topics: Analysis of Variance; Animals; Autoradiography; Cell Count; Corpus Striatum; DNA-Binding Proteins; Dopamine Agents; Drug Administration Schedule; Drug Interactions; Dynorphins; Early Growth Response Protein 1; Enkephalins; Gene Expression Regulation; Immediate-Early Proteins; In Situ Hybridization; Levodopa; Male; Neural Pathways; Neurons; Oxidopamine; Rats; Rats, Sprague-Dawley; RNA, Messenger; Substantia Nigra; Transcription Factors; Transcriptional Activation | 2005 |
Neuroprotection induced by the adenosine A2A antagonist CSC in the 6-OHDA rat model of parkinsonism: effect on the activity of striatal output pathways.
Topics: Adenosine A2 Receptor Antagonists; Animals; Caffeine; Cell Count; Dynorphins; Enkephalins; Globus Pallidus; Immunohistochemistry; In Situ Hybridization; Male; Microinjections; Neostriatum; Neural Pathways; Neuroprotective Agents; Oxidopamine; Parkinson Disease, Secondary; Protein Precursors; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; RNA, Messenger; Stereotyped Behavior; Substantia Nigra; Sympatholytics; Tyrosine 3-Monooxygenase | 2005 |
ERK phosphorylation and FosB expression are associated with L-DOPA-induced dyskinesia in hemiparkinsonian mice.
Topics: Animals; Antiparkinson Agents; Behavior, Animal; Blotting, Western; Corpus Striatum; Disease Models, Animal; Dopamine; Drug Administration Schedule; Dyskinesia, Drug-Induced; Dyskinesias; Enkephalins; Extracellular Signal-Regulated MAP Kinases; Gene Expression; Immunohistochemistry; In Situ Hybridization; Levodopa; Locomotion; Male; Mice; Mice, Inbred C57BL; Motor Activity; Oxidopamine; Parkinsonian Disorders; Phosphorylation; Protein Precursors; Proto-Oncogene Proteins c-fos; RNA, Messenger; Statistics, Nonparametric; Time Factors | 2006 |
Partial dopamine loss enhances activated caspase-3 activity: differential outcomes in striatal projection systems.
Topics: Animals; Apoptosis; Caspase 3; Caspases; Corpus Striatum; Disease Models, Animal; Disease Progression; Dopamine; Efferent Pathways; Enkephalins; Enzyme Activation; Male; Mitochondrial Proteins; Nerve Degeneration; Oxidopamine; Parkinsonian Disorders; Rats; Rats, Sprague-Dawley; Substantia Nigra; Sympatholytics; Tyrosine 3-Monooxygenase; Up-Regulation | 2005 |
Dysfunction of the cortico-basal ganglia-cortical loop in a rat model of early parkinsonism is reversed by metabotropic glutamate receptor 5 antagonism.
Topics: Animals; Basal Ganglia; Cerebral Cortex; Denervation; Dopamine Uptake Inhibitors; Electron Transport Complex IV; Enkephalins; Excitatory Amino Acid Antagonists; In Situ Hybridization; Male; Mazindol; Neostriatum; Nerve Net; Neurons; Oxidopamine; Parkinson Disease, Secondary; Protein Precursors; Rats; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; RNA, Messenger; Sympatholytics; Tachykinins; Thalamus | 2005 |
Postnatal administration of D1 dopamine agonist reverses neonatal dopaminergic lesion-induced changes in striatal enkephalin and substance P systems.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; 3,4-Dihydroxyphenylacetic Acid; Adrenergic Agents; Animals; Animals, Newborn; Corpus Striatum; Dopamine; Drug Interactions; Enkephalins; Female; Gene Expression; Humans; Male; Oxidopamine; Pregnancy; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Substance P | 2006 |
Reversion of levodopa-induced motor fluctuations by the A2A antagonist CSC is associated with an increase in striatal preprodynorphin mRNA expression in 6-OHDA-lesioned rats.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adenosine; Adrenergic Agents; Animals; Caffeine; Corpus Striatum; Dynorphins; Dyskinesias; Enkephalins; Immunohistochemistry; In Situ Hybridization; Levodopa; Male; Oxidopamine; Parkinsonian Disorders; Protein Precursors; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; RNA, Messenger | 2006 |
Unilateral 6-hydroxydopamine lesion of dopamine neurons and subchronic L-DOPA administration in the adult rat alters the expression of the vesicular GABA transporter in different subsets of striatal neurons and in the substantia nigra, pars reticulata.
Topics: Animals; Antiparkinson Agents; Corpus Striatum; Dopamine; Down-Regulation; Drug Administration Schedule; Enkephalins; Functional Laterality; gamma-Aminobutyric Acid; Gene Expression Regulation; Levodopa; Male; Neurons; Oxidopamine; Parkinsonian Disorders; Protein Precursors; Rats; Rats, Sprague-Dawley; RNA, Messenger; Substantia Nigra; Synaptic Transmission; Up-Regulation; Vesicular Inhibitory Amino Acid Transport Proteins | 2007 |
Characterization of the antiparkinsonian effects of the new adenosine A2A receptor antagonist ST1535: acute and subchronic studies in rats.
Topics: Adenine; Adenosine A2 Receptor Antagonists; Adrenergic Agents; Animals; Antiparkinson Agents; Behavior, Animal; Corpus Striatum; Dynorphins; Enkephalins; Glutamate Decarboxylase; Isoenzymes; Levodopa; Male; Oxidopamine; Parkinson Disease, Secondary; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tacrine; Tremor; Triazoles | 2007 |
Changes in the prodynorphin gene and DARPP-32 state in 6-OHDA-lesioned rats following long-term treatment with l-dopa.
Topics: Amino Acid Sequence; Animals; Basal Ganglia; Brain Chemistry; Dopamine; Dopamine and cAMP-Regulated Phosphoprotein 32; Drug Administration Schedule; Dyskinesia, Drug-Induced; Enkephalins; Excitatory Amino Acid Antagonists; Female; Gene Expression Regulation; Levodopa; Male; Neural Pathways; Neurotoxins; Oxidopamine; Parkinsonian Disorders; Phosphorylation; Protein Precursors; Rats; Rats, Sprague-Dawley; RNA, Messenger; Threonine; Time | 2007 |
Striatal output markers do not alter in response to circling behaviour in 6-OHDA lesioned rats produced by acute or chronic administration of the monoamine uptake inhibitor BTS 74 398.
Topics: Adrenergic Agents; Animals; Antiparkinson Agents; Behavior, Animal; Chlorobenzenes; Corpus Striatum; Cyclobutanes; Dynorphins; Enkephalins; Gene Expression; In Situ Hybridization; Levodopa; Male; Motor Activity; Oxidopamine; Parkinsonian Disorders; Rats; Rats, Wistar; RNA, Messenger; Substance P; Time | 2008 |
Behavioral and biochemical correlates of the dyskinetic potential of dopaminergic agonists in the 6-OHDA lesioned rat.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Antiparkinson Agents; Corpus Striatum; Dopamine; Dopamine Agonists; Dynorphins; Dyskinesia, Drug-Induced; Enkephalins; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Indoles; Male; Motor Activity; Neural Pathways; Opioid Peptides; Oxidopamine; Parkinsonian Disorders; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; RNA, Messenger | 2008 |
Oral creatine supplementation attenuates L-DOPA-induced dyskinesia in 6-hydroxydopamine-lesioned rats.
Topics: Administration, Oral; Analysis of Variance; Animals; Creatine; Dietary Supplements; Disease Models, Animal; Dyskinesia, Drug-Induced; Energy Metabolism; Enkephalins; Female; In Vitro Techniques; Levodopa; Neostriatum; Neuroprotective Agents; Oxidopamine; Parkinsonian Disorders; Phosphocreatine; Protein Precursors; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; RNA, Messenger; Statistics, Nonparametric | 2009 |
Antagonizing L-type Ca2+ channel reduces development of abnormal involuntary movement in the rat model of L-3,4-dihydroxyphenylalanine-induced dyskinesia.
Topics: Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Cerebrum; Dendritic Spines; Disease Models, Animal; Dose-Response Relationship, Drug; Dyskinesia, Drug-Induced; Enkephalins; Isradipine; Levodopa; Male; Motor Activity; Nimodipine; Oxidopamine; Protein Precursors; Rats; Rats, Wistar; RNA, Messenger; Sympatholytics | 2009 |
Dopamine D3 receptor stimulation underlies the development of L-DOPA-induced dyskinesia in animal models of Parkinson's disease.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Antiparkinson Agents; Benzopyrans; Callithrix; Corpus Striatum; Disease Models, Animal; Dopamine and cAMP-Regulated Phosphoprotein 32; Dopamine Antagonists; Dyskinesia, Drug-Induced; Enkephalins; Female; Levodopa; Male; Oxidopamine; Parkinsonian Disorders; Protein Precursors; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Dopamine D3; RNA, Messenger | 2009 |
Striatal alterations of secretogranin-1, somatostatin, prodynorphin, and cholecystokinin peptides in an experimental mouse model of Parkinson disease.
Topics: Amino Acid Sequence; Animals; Cholecystokinin; Chromogranin B; Disease Models, Animal; Enkephalins; Mice; Molecular Sequence Data; Neostriatum; Oxidopamine; Parkinson Disease; Peptides; Postmortem Changes; Protein Precursors; Reproducibility of Results; Somatostatin; Tissue Extracts; Tyrosine 3-Monooxygenase | 2009 |
Effects of early vs. late initiation of levodopa treatment in hemiparkinsonian rats.
Topics: Animals; Corpus Striatum; Dopamine Plasma Membrane Transport Proteins; Dynorphins; Dyskinesias; Electron Transport Complex IV; Enkephalins; Glutamate Decarboxylase; Immunohistochemistry; In Situ Hybridization; Levodopa; Male; Neurons; Oxidopamine; Parkinson Disease, Secondary; Protein Precursors; Rats; Rats, Sprague-Dawley; RNA, Messenger; Substantia Nigra; Subthalamic Nucleus | 2009 |
Pre-treatment with dopamine agonists influence L-dopa mediated rotations without affecting abnormal involuntary movements in the 6-OHDA lesioned rat.
Topics: Animals; Antiparkinson Agents; Bromocriptine; Corpus Striatum; Dopamine Agonists; Dyskinesia, Drug-Induced; Enkephalins; Female; Indoles; Levodopa; Oxidopamine; Parkinsonian Disorders; Piribedil; Protein Precursors; Rats; Rats, Sprague-Dawley; RNA, Messenger; Rotation; Time Factors | 2010 |
Calcium-permeable AMPA receptors are involved in the induction and expression of l-DOPA-induced dyskinesia in Parkinson's disease.
Topics: Adamantane; Animals; Antiparkinson Agents; Behavior, Animal; Benserazide; Brain; Calcium; Callithrix; Dyskinesia, Drug-Induced; Enkephalins; Levodopa; Male; Motor Activity; Oxidopamine; Parkinson Disease; Protein Precursors; Rats; Rats, Sprague-Dawley; Receptors, AMPA | 2010 |
Deletion of adenosine A₁ or A(₂A) receptors reduces L-3,4-dihydroxyphenylalanine-induced dyskinesia in a model of Parkinson's disease.
Topics: Adrenergic Agents; Animals; Antiparkinson Agents; Caffeine; Corpus Striatum; Disease Models, Animal; Dynorphins; Dyskinesia, Drug-Induced; Enkephalins; Gene Expression Regulation; Levodopa; Mice; Mice, Inbred C57BL; Mice, Knockout; Oxidopamine; Parkinson Disease; Protein Precursors; Purinergic P1 Receptor Antagonists; Receptor, Adenosine A1; Receptor, Adenosine A2A; RNA, Messenger; Statistics, Nonparametric; Time Factors | 2011 |
Adaptive gene expression changes on the healthy side of parkinsonian rats.
Topics: Adaptation, Physiological; Adrenergic Agents; Animals; Cerebral Cortex; Disease Models, Animal; Dopamine Plasma Membrane Transport Proteins; Dynorphins; Enkephalins; Female; Functional Laterality; Gene Expression Profiling; Locomotion; Neostriatum; Nerve Tissue Proteins; Neural Pathways; Oxidopamine; Parkinsonian Disorders; Random Allocation; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; RNA, Messenger; Tyrosine 3-Monooxygenase | 2013 |
A role for Sv2c in basal ganglia functions.
Topics: Animals; Basal Ganglia; Cocaine; Corpus Striatum; Dopaminergic Neurons; Enkephalins; Gene Knockdown Techniques; Locomotion; Male; Maze Learning; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Mice, Knockout; MPTP Poisoning; Nerve Tissue Proteins; Oxidopamine; Tyrosine 3-Monooxygenase | 2013 |
Performance of movement in hemiparkinsonian rats influences the modifications induced by dopamine agonists in striatal efferent dynorphinergic neurons.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Adrenergic Agents; Analysis of Variance; Animals; Apomorphine; Corpus Striatum; Disease Models, Animal; Dopamine Agonists; Dynorphins; Early Growth Response Protein 1; Enkephalins; Functional Laterality; Gene Expression Regulation; Male; Motor Neurons; Movement; Oxidopamine; Parkinson Disease; Rats; Rats, Sprague-Dawley; RNA, Messenger | 2013 |
RGS4 is involved in the generation of abnormal involuntary movements in the unilateral 6-OHDA-lesioned rat model of Parkinson's disease.
Topics: Animals; Antiparkinson Agents; Cells, Cultured; Corpus Striatum; Dyskinesia, Drug-Induced; Enkephalins; Functional Laterality; Gene Expression; Genetic Therapy; Levodopa; Male; Oligonucleotides, Antisense; Oxidopamine; Parkinsonian Disorders; Protein Precursors; Rats, Sprague-Dawley; RGS Proteins; RNA, Messenger; Up-Regulation | 2014 |
From unilateral to bilateral parkinsonism: Effects of lateralization on dyskinesias and associated molecular mechanisms.
Topics: Animals; Antiparkinson Agents; Corpus Striatum; Dynorphins; Dyskinesia, Drug-Induced; Enkephalins; Functional Laterality; Levodopa; Male; Motor Activity; Oxidopamine; Parkinsonian Disorders; Protein Precursors; Rats, Sprague-Dawley; RNA, Messenger | 2015 |
Enkephalin and dynorphin neuropeptides are differently correlated with locomotor hypersensitivity and levodopa-induced dyskinesia in parkinsonian rats.
Topics: Analysis of Variance; Animals; Antiparkinson Agents; Disease Models, Animal; Dynorphins; Dyskinesia, Drug-Induced; Enkephalins; Female; Gene Expression Regulation; Levodopa; Oxidopamine; Parkinson Disease; Protein Precursors; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; RNA, Messenger; Statistics as Topic; Sympatholytics; Tyrosine 3-Monooxygenase | 2016 |
l-DOPA-induced dyskinesia is associated with a deficient numerical downregulation of striatal tyrosine hydroxylase mRNA-expressing neurons.
Topics: Animals; Antiparkinson Agents; Corpus Striatum; Disease Models, Animal; Down-Regulation; Dyskinesia, Drug-Induced; Enkephalins; Levodopa; Male; Medial Forebrain Bundle; Mice, Inbred C57BL; Neuronal Plasticity; Neurons; Oxidopamine; Protein Precursors; RNA, Messenger; Tyrosine 3-Monooxygenase | 2016 |
Selegiline increases on time without exacerbation of dyskinesia in 6-hydroxydopamine-lesioned rats displaying l-Dopa-induced wearing-off and abnormal involuntary movements.
Topics: Animals; Antiparkinson Agents; Benserazide; Cytoskeletal Proteins; Disease Models, Animal; Drug Therapy, Combination; Dyskinesia, Drug-Induced; Enkephalins; Levodopa; Male; Movement; Nerve Tissue Proteins; Oxidopamine; Parkinsonian Disorders; Protein Precursors; Rats, Sprague-Dawley; RNA, Messenger; Selegiline; Time Factors | 2018 |
Diverse serotonin actions of vilazodone reduce l-3,4-dihidroxyphenylalanine-induced dyskinesia in hemi-parkinsonian rats.
Topics: Animals; Antiparkinson Agents; Disease Models, Animal; Dynorphins; Dyskinesia, Drug-Induced; Enkephalins; Gene Expression Regulation; Levodopa; Male; Oxidopamine; Parkinsonian Disorders; Piperazines; Protein Precursors; Proto-Oncogene Proteins c-fos; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; RNA, Messenger; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Time Factors; Vilazodone Hydrochloride | 2018 |