enkephalin, leucine has been researched along with normorphine in 28 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 22 (78.57) | 18.7374 |
| 1990's | 6 (21.43) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Knapp, RJ; Yamamura, HI | 1 |
| LoPresti, D; Porreca, F; Ward, SJ | 1 |
| Baba, A; Doi, M; Inoue, M; Ishida, T; Iwata, H; Katagawa, Y; Kitamura, K; Sadatome, T; Yara, H; Yasuda, M | 1 |
| Leek, BF; Maas, CL | 1 |
| Haaseth, RC; Heyman, JS; Mosberg, HI; Porreca, F; Vaught, JL | 1 |
| Christie, MJ; North, RA; Williams, JT | 2 |
| Nunan, L; Porreca, F; Sheldon, RJ | 1 |
| Illes, P; Ramme, D | 1 |
| Gardner, EL; Tempel, A; Zukin, RS; Zukin, SR | 1 |
| Hayes, AG; Sheehan, MJ; Tyers, MB | 1 |
| Chavkin, C; Goldstein, A; James, IF | 1 |
| Huidobro-Toro, JP; Way, EL; Yoshimura, K | 1 |
| Hagan, RM; Hughes, IE | 1 |
| Williams, J; Zieglgänsberger, W | 1 |
| Huidobro-Toro, JP; Way, EL | 1 |
| Bläsig, J; Brantl, V; Henschen, A; Lottspeich, F; Teschemacher, H | 1 |
| North, RA; Shefner, SA; Zukin, RS | 1 |
| Egan, TM; North, RA | 1 |
| Gintzler, AR; Scalisi, JA | 1 |
| Burks, TF; Galligan, JJ; Gee, K; Hruby, VJ; Hurst, R; Mosberg, HI; Yamamura, HI | 1 |
| Miller, L; Shaw, JS | 1 |
| Ackermann, RF; Caldecott-Hazard, S; Engel, J; Frederickson, RC; Liebeskind, JC; Shavit, Y | 1 |
| Drack, E; Halter, F; Scheurer, U; Varga, L | 1 |
| Henderson, G; Pepper, CM | 1 |
| Osborne, PB; Williams, JT | 1 |
| Magyar, A; Medzihradszky, K; Rónai, AZ | 1 |
| Adapa, ID; Auh, JS; Berzetei-Gurske, IP; Brandt, SR; Craymer, K; Farrington, L; Haggart, D; Kennedy, JM; O'Brien, A; Polgar, WE; Rodriguez, L; Schwartz, RW; Toll, L; White, A | 1 |
28 other study(ies) available for enkephalin, leucine and normorphine
| Article | Year |
|---|---|
[3H][D-Pen2, D-Pen5]enkephalin binding to delta opioid receptors on intact neuroblastoma-glioma (NG 108-15) hybrid cells.
Topics: Animals; Binding, Competitive; Cell Survival; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Hybrid Cells; Kinetics; Mice; Models, Biological; Morphine; Morphine Derivatives; Receptors, Opioid | 1990 |
Opioid agonist affinity in the guinea-pig ileum and mouse vas deferens.
Topics: Animals; Cyclazocine; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Ethylketocyclazocine; Guinea Pigs; Ileum; Male; Methadone; Mice; Morphine; Morphine Derivatives; Naltrexone; Receptors, Opioid; Vas Deferens | 1990 |
An attempt to structurally convert mu-selective morphine toward delta-receptor binding: dimerization based on enkephalin conformation.
Topics: Animals; Binding, Competitive; Brain; Chemical Phenomena; Chemistry, Physical; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; In Vitro Techniques; Male; Mice; Morphine; Morphine Derivatives; Muscle Contraction; Muscle, Smooth; Protein Conformation; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Vas Deferens | 1990 |
Central and local actions of opioids upon reticulo-ruminal motility in sheep.
Topics: Animals; Bradykinin; Enkephalins; Gastrointestinal Motility; In Vitro Techniques; Loperamide; Morphine Derivatives; Muscle Contraction; Naloxone; Narcotics; Prostaglandins E; Reticulum; Rumen; Sheep; Substance P | 1985 |
Modulation of mu-mediated antinociception by delta agonists in the mouse: selective potentiation of morphine and normorphine by [D-Pen2,D-Pen5]enkephalin.
Topics: Animals; Drug Synergism; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Injections, Intraventricular; Male; Mice; Mice, Inbred ICR; Morphine; Morphine Derivatives; Narcotics; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu | 1989 |
Cellular mechanisms of opioid tolerance: studies in single brain neurons.
Topics: Animals; Drug Tolerance; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; In Vitro Techniques; Locus Coeruleus; Male; Membrane Potentials; Morphine; Morphine Derivatives; Naltrexone; Neurons; Potassium; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, mu | 1987 |
U50,488H differentially antagonizes the bladder effects of mu agonists at spinal sites.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Endorphins; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Morphine; Morphine Derivatives; Muscle Contraction; Pyrrolidines; Rats; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Urinary Bladder | 1988 |
Differential effect of stimulation strength in mouse vas deferens on inhibition of neuroeffector transmission by receptor type selective opioids.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Cyclazocine; Dynorphins; Electric Stimulation; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Ethylketocyclazocine; In Vitro Techniques; Male; Mice; Morphine Derivatives; Muscle, Smooth; Neuromuscular Junction; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Synaptic Transmission | 1986 |
Interaction of [3H](-)-SKF-10,047 with brain sigma receptors: characterization and autoradiographic visualization.
Topics: Animals; Autoradiography; Binding, Competitive; Brain; Cell Membrane; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Male; Morphine Derivatives; Narcotics; Phenazocine; Rats; Rats, Inbred Strains; Receptors, Opioid; Tissue Distribution | 1986 |
Irreversible selective blockade of kappa-opioid receptors in the guinea-pig ileum.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Diuresis; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Guinea Pigs; Ileum; In Vitro Techniques; Male; Morphine Derivatives; Naltrexone; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, kappa | 1986 |
Tolerance to opioids in single locus coeruleus neurons of the rat.
Topics: Animals; Drug Tolerance; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; In Vitro Techniques; Locus Coeruleus; Morphine; Morphine Derivatives; Neurons; Rats | 1986 |
Dynorphin is a specific endogenous ligand of the kappa opioid receptor.
Topics: Analgesics, Opioid; Animals; Binding, Competitive; Brain; Cyclazocine; Dynorphins; Endorphins; Enkephalin, Leucine; Enkephalins; Ethylketocyclazocine; Guinea Pigs; In Vitro Techniques; Ligands; Morphine Derivatives; Myenteric Plexus; Naloxone; Peptide Fragments; Receptors, Opioid | 1982 |
Potency of three opiate antagonists to reverse the inhibitory activity of dynorphin, enkephalins and opioid-like alkaloids on the guinea pig ileum.
Topics: Animals; Azocines; Benzomorphans; Cyclazocine; Dynorphins; Endorphins; Enkephalins; Ethylketocyclazocine; Guinea Pigs; Ileum; In Vitro Techniques; Male; Morphine Derivatives; Muscle, Smooth; Naloxone; Narcotic Antagonists | 1982 |
Opioid receptor sub-types involved in the control of transmitter release in cortex of the brain of the rat.
Topics: Animals; beta-Lipotropin; Cerebral Cortex; Clomipramine; Edetic Acid; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Estradiol; In Vitro Techniques; Male; Morphine; Morphine Derivatives; Naloxone; Narcotics; Neurotransmitter Agents; Norepinephrine; Peptide Fragments; Rats; Rats, Inbred Strains; Receptors, Opioid; Serotonin | 1984 |
Mature spinal ganglion cells are not sensitive to opiate receptor mediated actions.
Topics: Action Potentials; Aminopyridines; Animals; Barium; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Enkephalins; gamma-Aminobutyric Acid; Ganglia, Spinal; Iontophoresis; Morphine; Morphine Derivatives; Naloxone; Narcotics; Rats; Receptors, Opioid | 1981 |
Comparative study on the effect of morphine and the opioid-like peptides in the vas deferens of rodents: species and strain differences, evidence for multiple opiate receptors.
Topics: Animals; beta-Endorphin; Endorphins; Enkephalin, Methionine; Enkephalins; Guinea Pigs; Male; Mice; Mice, Inbred ICR; Morphine; Morphine Derivatives; Peptides; Rats; Receptors, Opioid; Species Specificity; Vas Deferens | 1981 |
Opioid activities of beta-casomorphins.
Topics: Animals; Caseins; Endorphins; Enkephalin, Methionine; Enkephalins; Guinea Pigs; Ileum; Male; Morphine Derivatives; Myenteric Plexus; Rats; Receptors, Opioid; Structure-Activity Relationship; Vas Deferens | 1981 |
Opiate effects on rabbit vagus nerve: electrophysiology and radioligand binding.
Topics: Action Potentials; Animals; Endorphins; Enkephalin, Leucine-2-Alanine; Enkephalins; Evoked Potentials; Kinetics; Morphine; Morphine Derivatives; Nodose Ganglion; Rabbits; Receptors, Opioid; Structure-Activity Relationship; Vagus Nerve | 1981 |
Both mu and delta opiate receptors exist on the same neuron.
Topics: Animals; Dihydromorphine; Electric Conductivity; Endorphins; Enkephalin, Leucine-2-Alanine; Enkephalins; Guinea Pigs; Ileum; Morphine Derivatives; Myenteric Plexus; Neurons; Receptors, Opioid | 1981 |
Physiological correlates of multiple subtypes of enteric opiate receptor; functional analysis of myenteric delta receptors.
Topics: Animals; Dose-Response Relationship, Drug; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Enkephalins; Guinea Pigs; Ileum; Morphine; Morphine Derivatives; Myenteric Plexus; Receptors, Opioid; Receptors, Opioid, delta | 1982 |
[D-Pen2, L-Cys5]enkephalinamide and[D-Pen2, D-Cys5] enkephalinamide, conformationally constrained cyclic enkephalinamide analogs with delta receptor specificity.
Topics: Animals; Biological Assay; Brain; Endorphins; Enkephalins; Female; Guinea Pigs; Ileum; Male; Mice; Morphine Derivatives; Muscle Contraction; Rats; Rats, Inbred Strains; Receptors, Opioid; Structure-Activity Relationship; Vas Deferens | 1982 |
Multiple opiate receptors in the mouse vas deferens.
Topics: Animals; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; In Vitro Techniques; Male; Mice; Morphine Derivatives; Muscle, Smooth; Receptors, Opioid; Temperature; Vas Deferens | 1983 |
Behavioral and electrographic effects of opioids on kindled seizures in rats.
Topics: Animals; Behavior, Animal; Drug Tolerance; Enkephalins; Guinea Pigs; Humans; Kindling, Neurologic; Male; Mice; Morphine; Morphine Derivatives; Naloxone; Narcotics; Rats; Rats, Inbred Strains; Seizures; Substance Withdrawal Syndrome; Vas Deferens | 1982 |
Morphine-like action of enkephalin analog FK 33-824 on motility of the isolated rat colon.
Topics: Animals; Colon; D-Ala(2),MePhe(4),Met(0)-ol-enkephalin; Drug Interactions; Endorphins; Enkephalins; Gastrointestinal Motility; In Vitro Techniques; Male; Morphine Derivatives; Narcotic Antagonists; Pressure; Rats; Rats, Inbred Strains; Tetrodotoxin | 1981 |
Opiates and opioid peptides hyperpolarize locus coeruleus neurons in vitro.
Topics: Animals; Endorphins; Enkephalin, Methionine; Enkephalins; Guinea Pigs; Locus Coeruleus; Membrane Potentials; Morphine Derivatives; Naloxone; Neurons | 1980 |
Characterization of acute homologous desensitization of mu-opioid receptor-induced currents in locus coeruleus neurones.
Topics: Animals; Brain; Dose-Response Relationship, Drug; Drug Tolerance; Enkephalins; Enzyme Inhibitors; Locus Coeruleus; Male; Microcystins; Morphine Derivatives; Patch-Clamp Techniques; Peptides, Cyclic; Rats; Rats, Wistar; Receptors, Opioid, mu; Time Factors | 1995 |
Kinetic parameters of antagonism by the delta opioid receptor selective peptide antagonist Boc-Tyr-Pro-Gly-Phe-Leu-Thr against selective and non-selective agonists in the mouse vas deferens.
Topics: Analgesics; Animals; Anticonvulsants; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Enkephalins; In Vitro Techniques; Kinetics; Male; Mice; Mice, Inbred Strains; Morphine Derivatives; Naltrexone; Oligopeptides; Pyrroles; Receptors, Opioid, delta; Thiophenes; Vas Deferens | 1993 |
Standard binding and functional assays related to medications development division testing for potential cocaine and opiate narcotic treatment medications.
Topics: Animals; Aorta, Thoracic; Cocaine; Cyclic AMP; Electric Stimulation; Guinea Pigs; Humans; Ileum; In Vitro Techniques; Male; Mice; Muscle, Smooth; Opioid-Related Disorders; Rats; Receptors, Dopamine; Receptors, Opioid; Receptors, Serotonin; Substance-Related Disorders | 1998 |